Research Topics
| C MinierSummaryCountry: France Publications
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Publications
Rhodamine exclusion activity in primary cultured turbot (Scophthalmus maximus) hepatocytesRenaud Tutundjian
Laboratoire d Ecotoxicologie, UPRES EA 3222, Universite du Havre, France
Mar Environ Res 54:443-7. 2002..Rhodamine B accumulated in the whole cytoplasm, with more concentrated areas that might correspond to the lysosomal compartment and the cell membrane...
Expression and activity of a multixenobiotic resistance system in the Pacific oyster Crassostrea gigasC Minier
LEMA, UPRES EA 3222, University of Le Havre, France
Mar Environ Res 54:455-9. 2002..The oyster MXR system is thus becoming active in adult oyster and could be of importance in environmentally contaminated areas...
In vitro study of the effects of cadmium on the activation of the estrogen response element using the YES screenXavier Denier
Laboratory of Ecotoxicology, University of Le Havre, BP 540, 76058 Le Havre, France
Mar Environ Res 66:108-10. 2008..A maximal effect was observed at 0.5 microM with a ten fold reduction of the 17beta-estradiol EC50...
Flounder health status in the Seine Bay. A multibiomarker studyC Minier
Laboratory of Ecotoxicology, University of Le Havre, 2BP540, 25 rue Philippe Lebon, F 76058 Le Havre, France
Mar Environ Res 50:373-7. 2000....
Multixenobiotic resistance, acetyl-choline esterase activity and total oxyradical scavenging capacity of the Arctic spider crab, Hyasaraneus, following exposure to bisphenol A, tetra bromo diphenyl ether and diallyl phthalateChristophe Minier
LEMA, EA 3222, Universite du Havre, 25, rue Philippe Lebon, BP540, F 76058 Le Havre, France
Mar Pollut Bull 56:1410-5. 2008..05, n=5). These results thus suggest the potential detrimental effects of DPA even at concentration as low as 50 microg/L on H. araneus...
A pollution-monitoring pilot study involving contaminant and biomarker measurements in the Seine Estuary, France, using zebra mussels (Dreissena polymorpha)Christophe Minier
Laboratory of Ecotoxicology LEMA, EA 3222, Universite du Havre, 25 rue Philippe Lebon, BP 540, 76058 Le Havre, France
Environ Toxicol Chem 25:112-9. 2006..This study also shows that chemical and biological measurements bring different but complementary results that can help diagnose environmental health...
Genetic and immunological characterisation of a multixenobiotic resistance system in the turbot (Scophthalmus maximus)Renaud Tutundjian
Laboratoire d Ecotoxicologie, UPRES EA 3222, Universite du Havre, 25 rue Philippe Lebon, BP 540, 76058 Le Havre, France
Comp Biochem Physiol B Biochem Mol Biol 132:463-71. 2002..This tissue specific expression suggests a role for the identified mechanism in protection against endogenous or exogenous toxic compounds...
Endocrine effects of the tapeworm Ligula intestinalis in its teleost host, the roach ( Rutilus rutilus)P Geraudie
Laboratory of Ecotoxicology, University of Le Havre, BP 540, 76058 Le Havre, France
Parasitology 137:697-704. 2010..These results demonstrate significant negative effects on the reproductive function of wild roach infected by the tapeworm L. intestinalis collected from a site with low contamination...
Ligula intestinalis infection is associated with alterations of both brain and gonad aromatase expression in roach (Rutilus rutilus)C Boulangé-Lecomte
Laboratory of Ecotoxicology, University of Le Havre, BP 540, Le Havre, France
J Helminthol 85:339-44. 2011..Finally, quantitative PCR was confirmed as a sensitive approach, enabling aromatase status to be defined in the poorly developed gonads of ligulosed individuals...
A new in vitro screening bioassay for the ecotoxicological evaluation of the estrogenic responses of environmental chemicals using roach (Rutilus rutilus) liver explant cultureMarie Gerbron
Laboratory of Ecotoxicology, UPRES EA 3222, University of Le Havre, BP 540, 76058 Le Havre, France
Environ Toxicol 25:510-6. 2010..Overall, this study shows that the bioassay could provide valuable information on endocrine disrupting chemicals including metabolites and mixtures of compounds...
Seasonal variations and alterations of sex steroid levels during the reproductive cycle of male roach (Rutilus rutilus)Perrine Geraudie
Laboratory of Ecotoxicology, University of Le Havre, Le Havre, France
Mar Environ Res 69:S53-5. 2010..Contrary to the E2 and 11-KT sex steroids, plasma P concentration was not significantly affected in fish inhabiting impacted areas...
Impact of endocrine toxicants on survival, development, and reproduction of the estuarine copepod Eurytemora affinis (Poppe)Joëlle Forget-Leray
Laboratory of Ecotoxicology, UPRES EA 3222, UFR de Sciences et Techniques, Universite du Havre, 25 rue Philippe Lebon, BP 540, 76058 Le Havre Cedex, France
Ecotoxicol Environ Saf 60:288-94. 2005..The results suggest that endocrine disruption could occur in copepods following exposure to estrogenic compounds, especially if they are exposed starting from embryonic development...
Roach (Rutilus rutilus) reproductive cycle: a study of biochemical and histological parameters in a low contaminated sitePerrine Geraudie
Laboratory of Ecotoxicology, University of Le Havre, Le Havre, France
Fish Physiol Biochem 36:767-77. 2010..Conversely, elevated temperatures during the winter lead to an earlier gonad maturation...
Detection of environmental mutagens using the FACIM assayJ Couteau
LEMA, EA 3222, IFRMP 23, University of Le Havre, 76058 Le Havre Cedex, France
Mar Environ Res 66:62-3. 2008..The present assay named FACIM II (Functional Analysis of Chemical-Induced TP53 Mutations) is more convenient than the FACIM I and more inducible than the SOS Chromotest to detect direct-acting mutagens in the environment...
Estrogenic activity of cadmium, copper and zinc in the yeast estrogen screenXavier Denier
Laboratory of Ecotoxicology, University of Le Havre, BP 540, 76058 Le Havre, France
Toxicol In Vitro 23:569-73. 2009..Maximum response led to decrease of the estradiol EC50 by a factor 10. This study indicates that cadmium, copper and zinc can act as potential endocrine disrupters by modulating the estrogenic activity of endogenous hormones...
Evidence of endocrine alteration in the red mullet, Mullus barbatus from the NW MediterraneanRebeca Martin-Skilton
Department of Environmental Chemistry, IIQAB-CSIC, Jordi Girona 18, 08034 Barcelona, Spain
Environ Pollut 141:60-8. 2006..Overall, this work provides first evidences of significant alterations in the endocrine system of red mullet from highly impacted areas in the NW Mediterranean...
Endocrine-related reproductive effects in molluscsImen Ketata
Ecotoxicologie Marine, UR 09 03, Universite de Sfax, IPEIS, BP 805, 3018 Sfax, Tunisia
Comp Biochem Physiol C Toxicol Pharmacol 147:261-70. 2008..This diversity constitutes an important opportunity to examine and understand new and alternative mechanisms for endocrine disruption...
Identification of the steroid fatty acid ester conjugates formed in vivo in Mytilus edulis as a result of exposure to estrogensPierre Labadie
Centre for Environmental Research, School of Life Sciences, University of Sussex, Brighton BN1 9QJ, UK
Steroids 72:41-9. 2007..edulis...
