Research Topics
| Yann MikaeloffSummaryCountry: France Publications
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Detail Information
Publications
Hepatitis B vaccination and the risk of childhood-onset multiple sclerosisYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie Pediatrique, Hopital Bicetre, INSERM U802, Universite Paris Sud XI, 78 Avenue du General LeClerc, 94275 Le Kremlin Bicetre cedex, France
Arch Pediatr Adolesc Med 161:1176-82. 2007..To investigate whether vaccination against hepatitis B (HB) increases the risk of incident multiple sclerosis (MS) in childhood in the short and long terms...
Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort studyPierre Ernst
Center for Clinical Epidemiology, Lady Davis Research Institute, Jewish General Hospital, Montreal, Canada
BMC Pulm Med 11:59. 2011..We hypothesised that inhaled corticosteroids (ICS) are a risk factor for herpes zoster especially among users of inhibitors of cytochrome P450 enzymes involved in their metabolism...
School performance in a cohort of children with CNS inflammatory demyelinationYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie Pédiatrique and Centre de Référence National des Maladies Inflammatoires du cerveau de l Enfant, Hopital Bicetre, Universite Paris Sud 11, Le Kremlin Bicetre, France
Eur J Paediatr Neurol 14:418-24. 2010..Acute CNS inflammatory demyelination in childhood may induce permanent cognitive impairment. However, there has been no epidemiological assessment of prognostic factors for school performance in a cohort of children with such a disease...- Clinically observed chickenpox and the risk of childhood-onset multiple sclerosisYann Mikaeloff
Service de Neurologie Pediatrique, CHU Bicetre, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre Cedex, France
Am J Epidemiol 169:1260-6. 2009..58 (95% confidence interval: 0.36, 0.92). The authors concluded that clinically observed chickenpox was associated with a lower risk of childhood-onset MS in a French population... - Hepatitis B vaccine and the risk of CNS inflammatory demyelination in childhoodYann Mikaeloff
Service de Neurologie Pediatrique, CHU Bicetre, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre Cedex, France
Neurology 72:873-80. 2009..The risk of CNS inflammatory demyelination associated with hepatitis B (HB) vaccine is debated, with studies reporting conflicting findings... - Effectiveness of early beta interferon on the first attack after confirmed multiple sclerosis: a comparative cohort studyYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie, Pédiatrique, Hopital Bicetre, INSERM U802, Universite Paris Sud 11, Le Kremlin Bicetre, France
Eur J Paediatr Neurol 12:205-9. 2008..In the absence of randomized controlled trials to support therapeutic decisions in pediatric MS (multiple sclerosis), comparative observational studies based on the real practice of physicians are important tools... - Parental smoking at home and the risk of childhood-onset multiple sclerosis in childrenYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie Pediatrique, Hopital Bicetre, INSERM U802, Universite Paris Sud 11, Le Kremlin Bicetre, France
Brain 130:2589-95. 2007..49 (1.53-4.08)-than in younger cases. Children exposed to parent smoking have a higher MS risk. The duration of exposure also affects the level of risk... - Infant and toddler disease score was useful for risk of hospitalization based on data from administrative claimsYann Mikaeloff
INSERM, UMR S149, Paris, France
J Clin Epidemiol 60:680-5. 2007..To develop the infant and toddler disease score (IDS), a population-based predictive tool of morbidity status in infants and toddlers, based on data from administrative claims... - Hepatitis B vaccine and risk of relapse after a first childhood episode of CNS inflammatory demyelinationYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie Pediatrique, Hopital Bicetre, INSERM U802, Universite Paris Sud 11, Le Kremlin Bicetre, France
Brain 130:1105-10. 2007.... - Acute disseminated encephalomyelitis cohort study: prognostic factors for relapseYann Mikaeloff
Service de Neurologie Pediatrique, Assistance Publique Hopitaux de Paris, Hopital Bicetre, INSERM U 802 and Université Paris Sud 11, Le Kremlin Bicetre, France
Eur J Paediatr Neurol 11:90-5. 2007..12) and no neurological sequelae after first attack (3.79; 1.12-12.85). Clinical and MRI prognostic factors for relapse in ADEM may contribute to an early distinction between monophasic and relapsing disease, which may be related to MS... - Prognostic factors for early severity in a childhood multiple sclerosis cohortYann Mikaeloff
Service de Neurologie Pediatrique, Hopital Bicetre, Assistance Publique Hopitaux de Paris, INSERM U802, Paris, France
Pediatrics 118:1133-9. 2006..The goal was to identify prognostic factors for an early severe course in a cohort of patients with childhood-onset multiple sclerosis, for the construction of a predictive tool... - MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhoodYann Mikaeloff
Service de Neurologie Pediatrique, CHU, Angers, France
Brain 127:1942-7. 2004..Their low sensitivity, however, shows that this prediction remains difficult... - First episode of acute CNS inflammatory demyelination in childhood: prognostic factors for multiple sclerosis and disabilityYann Mikaeloff
Service de Neurologie Pediatrique, Hopital Roger Salengro, Lille, France
J Pediatr 144:246-52. 2004..To evaluate prognostic factors for second attack and for disability in children presenting with an initial episode of central nervous system (CNS) demyelination... - Nonsteroidal anti-inflammatory drug use and the risk of severe skin and soft tissue complications in patients with varicella or zoster diseaseYann Mikaeloff
Pediatric Department, Assistance Publique Hopitaux de Paris, Bicetre University Hospital, Le Kremlin Bicetre, France
Br J Clin Pharmacol 65:203-9. 2008..The use of NSAIDs is also associated with a small increased risk of such complications in zoster disease in adults and the elderly. This study supports the limited prescription of NSAIDs in VZV infection... - What is acute disseminated encephalomyelitis (ADEM)?Marc Tardieu
Neurologie pédiatrique, Hopital Bicetre, Assistance Publique, Hopitaux de Paris, 78 rue du General Leclerc, 94275 Le Kremlin Bicetre cedex, France
Eur J Paediatr Neurol 8:239-42. 2004..Macrophage activation syndrome and different types of angiitis may mimic ADEM, because they can occur in the absence of the usual non neurological symptoms. Both entities require specific treatments... - Incidence and natural history of mucopolysaccharidosis type III in France and comparison with United Kingdom and GreeceBenedicte Heron
Hopital Trousseau, Centre de référence des maladies lysosomales, Paris, France
Am J Med Genet A 155:58-68. 2011..Notwithstanding the rapidity of further clinical deterioration, all MPSIII patients suffer early onset devastating neurological manifestations that deserve early treatment when available... - Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directionsBrenda Banwell
Department of Paediatrics, Division of Neurology, The Hospital for Sick Children, University of Toronto, Toronto, Canada
Lancet Neurol 6:887-902. 2007..Understanding the immunological consequences of these putative exposures will shed light on the early pathological changes in MS... - [Multiple sclerosis in children: environmental risk factors]Marc Tardieu
Neurologie pédiatrique, Hopital Bicetre, 78 rue du General Leclerc, 94275 Kremlin Bicêtre Inserm U802
Bull Acad Natl Med 192:507-9; discussion 509-10. 2008..The risk of MS was not increased by HBV vaccination, but was increased by passive smoking at home... - Natural history of multiple sclerosis with childhood onsetChristel Renoux
Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France
N Engl J Med 356:2603-13. 2007..The course and prognosis of childhood-onset multiple sclerosis have not been well described... - Severe memory impairment in a child with bihippocampal injury after status epilepticusIsabelle Jambaque
Laboratoire Cognition et Developpement, Institut de Psychologie, Universite Paris Descartes, Paris V, CNRS UMR 8605, 92774 Boulogne Billancourt, France
Dev Med Child Neurol 48:223-6. 2006..In contrast with children who develop such damage after anoxia, this may result in general cognitive impairment but also in more severe episodic memory deficit... - Topiramate pharmacokinetics in children with epilepsy aged from 6 months to 4 yearsYann Mikaeloff
Neuropediatric Department, University Hospital, Angers, France
Epilepsia 45:1448-52. 2004..To study the pharmacokinetics of topiramate (TPM) at steady state in children younger than 4 years comedicated with other antiepileptic drugs (AEDs)...