Research Topics
| Y MikaeloffSummaryCountry: France Publications
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Detail Information
Publications
[Optic pathway gliomas in neurofibromatosis type I. Longitudinal study of 30 cases in two multidisciplinary practices]Y Mikaeloff
Service de Neuropediatrie, Hopital Saint Vincent de Paul, 82, avenue Denfert Rochereau, 75674 Paris, France
Arch Pediatr 9:797-804. 2002..The aim of this study was to analyse the outcome of optic pathway gliomas in 30 children with neurofibromatosis type 1, the indications of treatment, and the follow-up and screening protocol...
Topiramate: efficacy and tolerability in children according to epilepsy syndromesYann Mikaeloff
Neuropediatric Department, Cochin Saint Vincent de Paul University Hospital, 82 Bd Denfert Rochereau, 75014 Paris, France
Epilepsy Res 53:225-32. 2003..Use of TPM should be considered in children under 4 years of age, and slow and progressive titration is important...
First episode of acute CNS inflammatory demyelination in childhood: prognostic factors for multiple sclerosis and disabilityYann Mikaeloff
Service de Neurologie Pediatrique, Hopital Roger Salengro, Lille, France
J Pediatr 144:246-52. 2004..To evaluate prognostic factors for second attack and for disability in children presenting with an initial episode of central nervous system (CNS) demyelination...
MRI prognostic factors for relapse after acute CNS inflammatory demyelination in childhoodYann Mikaeloff
Service de Neurologie Pediatrique, CHU, Angers, France
Brain 127:1942-7. 2004..Their low sensitivity, however, shows that this prediction remains difficult...
Clinical and EEG video-polygraphic features of epileptic spasms in a child with dihydropteridine reductase deficiency. Efficiency of hydrocortisoneY Mikaeloff
Service de Neuropediatrie, Hopital Saint Vincent de Paul, 82, avenue Denfert Rochereau, 75014 Paris, France
Epileptic Disord 2:213-7. 2000..A beneficial effect from hydrocortisone was then observed, with control of spasms and improvement of psychomotor delay...
Clinically observed chickenpox and the risk of childhood-onset multiple sclerosisYann Mikaeloff
Service de Neurologie Pediatrique, CHU Bicetre, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre Cedex, France
Am J Epidemiol 169:1260-6. 2009..58 (95% confidence interval: 0.36, 0.92). The authors concluded that clinically observed chickenpox was associated with a lower risk of childhood-onset MS in a French population...
Devastating epileptic encephalopathy in school-aged children (DESC): a pseudo encephalitisY Mikaeloff
Neuropediatric Department, University Hospital, Bicetre, France
Epilepsy Res 69:67-79. 2006....
Topiramate pharmacokinetics in children with epilepsy aged from 6 months to 4 yearsYann Mikaeloff
Neuropediatric Department, University Hospital, Angers, France
Epilepsia 45:1448-52. 2004..To study the pharmacokinetics of topiramate (TPM) at steady state in children younger than 4 years comedicated with other antiepileptic drugs (AEDs)...
Multiple sclerosis in children: clinical diagnosis, therapeutic strategies, and future directionsBrenda Banwell
Department of Paediatrics, Division of Neurology, The Hospital for Sick Children, University of Toronto, Toronto, Canada
Lancet Neurol 6:887-902. 2007..Understanding the immunological consequences of these putative exposures will shed light on the early pathological changes in MS...
Effectiveness of early beta interferon on the first attack after confirmed multiple sclerosis: a comparative cohort studyYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie, Pédiatrique, Hopital Bicetre, INSERM U802, Universite Paris Sud 11, Le Kremlin Bicetre, France
Eur J Paediatr Neurol 12:205-9. 2008..In the absence of randomized controlled trials to support therapeutic decisions in pediatric MS (multiple sclerosis), comparative observational studies based on the real practice of physicians are important tools...
Hepatitis B vaccine and risk of relapse after a first childhood episode of CNS inflammatory demyelinationYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie Pediatrique, Hopital Bicetre, INSERM U802, Universite Paris Sud 11, Le Kremlin Bicetre, France
Brain 130:1105-10. 2007....
Natural history of multiple sclerosis with childhood onsetChristel Renoux
Hopital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France
N Engl J Med 356:2603-13. 2007..The course and prognosis of childhood-onset multiple sclerosis have not been well described...
What is acute disseminated encephalomyelitis (ADEM)?Marc Tardieu
Neurologie pédiatrique, Hopital Bicetre, Assistance Publique, Hopitaux de Paris, 78 rue du General Leclerc, 94275 Le Kremlin Bicetre cedex, France
Eur J Paediatr Neurol 8:239-42. 2004..Macrophage activation syndrome and different types of angiitis may mimic ADEM, because they can occur in the absence of the usual non neurological symptoms. Both entities require specific treatments...
Acute disseminated encephalomyelitis cohort study: prognostic factors for relapseYann Mikaeloff
Service de Neurologie Pediatrique, Assistance Publique Hopitaux de Paris, Hopital Bicetre, INSERM U 802 and Université Paris Sud 11, Le Kremlin Bicetre, France
Eur J Paediatr Neurol 11:90-5. 2007..12) and no neurological sequelae after first attack (3.79; 1.12-12.85). Clinical and MRI prognostic factors for relapse in ADEM may contribute to an early distinction between monophasic and relapsing disease, which may be related to MS...
Prognostic factors for early severity in a childhood multiple sclerosis cohortYann Mikaeloff
Service de Neurologie Pediatrique, Hopital Bicetre, Assistance Publique Hopitaux de Paris, INSERM U802, Paris, France
Pediatrics 118:1133-9. 2006..The goal was to identify prognostic factors for an early severe course in a cohort of patients with childhood-onset multiple sclerosis, for the construction of a predictive tool...
Infant and toddler disease score was useful for risk of hospitalization based on data from administrative claimsYann Mikaeloff
INSERM, UMR S149, Paris, France
J Clin Epidemiol 60:680-5. 2007..To develop the infant and toddler disease score (IDS), a population-based predictive tool of morbidity status in infants and toddlers, based on data from administrative claims...
Hepatitis B vaccination and the risk of childhood-onset multiple sclerosisYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie Pediatrique, Hopital Bicetre, INSERM U802, Universite Paris Sud XI, 78 Avenue du General LeClerc, 94275 Le Kremlin Bicetre cedex, France
Arch Pediatr Adolesc Med 161:1176-82. 2007..To investigate whether vaccination against hepatitis B (HB) increases the risk of incident multiple sclerosis (MS) in childhood in the short and long terms...
Nonsteroidal anti-inflammatory drug use and the risk of severe skin and soft tissue complications in patients with varicella or zoster diseaseYann Mikaeloff
Pediatric Department, Assistance Publique Hopitaux de Paris, Bicetre University Hospital, Le Kremlin Bicetre, France
Br J Clin Pharmacol 65:203-9. 2008..The use of NSAIDs is also associated with a small increased risk of such complications in zoster disease in adults and the elderly. This study supports the limited prescription of NSAIDs in VZV infection...
[Multiple sclerosis in children: environmental risk factors]Marc Tardieu
Neurologie pédiatrique, Hopital Bicetre, 78 rue du General Leclerc, 94275 Kremlin Bicêtre Inserm U802
Bull Acad Natl Med 192:507-9; discussion 509-10. 2008..The risk of MS was not increased by HBV vaccination, but was increased by passive smoking at home...
Parental smoking at home and the risk of childhood-onset multiple sclerosis in childrenYann Mikaeloff
Assistance Publique Hopitaux de Paris, Service de Neurologie Pediatrique, Hopital Bicetre, INSERM U802, Universite Paris Sud 11, Le Kremlin Bicetre, France
Brain 130:2589-95. 2007..49 (1.53-4.08)-than in younger cases. Children exposed to parent smoking have a higher MS risk. The duration of exposure also affects the level of risk...
