Pierre Meneton

Summary

Country: France

Publications

  1. pmc Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice
    P Meneton
    Institut National de la Santé et de la Recherche Médicale INSERM U367, 17 Rue du Fer a Moulin, 75005 Paris, France
    Proc Natl Acad Sci U S A 98:2634-9. 2001
  2. ncbi Comparative roles of the renal apical sodium transport systems in blood pressure control
    P Meneton
    INSERM U367, Paris, France
    J Am Soc Nephrol 11:S135-9. 2000
  3. ncbi Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases
    Pierre Meneton
    Institut National de la Santé et de la Recherche Médicale U367, Département de Santé Publique et d Informatique Médicale, Faculté de Médecine Broussais Hôtel Dieu, Paris, France
    Physiol Rev 85:679-715. 2005
  4. ncbi Sodium and potassium handling by the aldosterone-sensitive distal nephron: the pivotal role of the distal and connecting tubule
    Pierre Meneton
    Unité 367 de l Institut National de la Santé et de la Recherche Médicale, 75005 Paris, France
    Am J Physiol Renal Physiol 287:F593-601. 2004
  5. ncbi Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors
    Sonia Bergaya
    Institut National de la Sante et de la Recherche Medicale, Unit 541, Hopital Lariboisiere, Paris, France
    Circ Res 94:1623-9. 2004
  6. ncbi Pendrin regulation in mouse kidney primarily is chloride-dependent
    Marion Vallet
    INSERM U652, IFR58, Institut des Cordeliers, Paris, France
    J Am Soc Nephrol 17:2153-63. 2006
  7. ncbi Inactivation of the Na-Cl co-transporter (NCC) gene is associated with high BMD through both renal and bone mechanisms: analysis of patients with Gitelman syndrome and Ncc null mice
    Laurence Nicolet-Barousse
    Departement de Physiologie, Hôpital Européen George Pompidou, Institut National de la Santé et de la Recherche Médicale INSERM U 652, IFR 58, Universite Paris V, Paris, France
    J Bone Miner Res 20:799-808. 2005
  8. ncbi Tissue kallikrein-deficient mice display a defect in renal tubular calcium absorption
    Nicolas Picard
    INSERM, Unité 652, and Institut Fédératif de Recherche 58, Paris, France
    J Am Soc Nephrol 16:3602-10. 2005
  9. ncbi Defective ENaC processing and function in tissue kallikrein-deficient mice
    Nicolas Picard
    INSERM U872 Centre de Recherche des Cordeliers, Universite Paris 5, Faculté de Médecine René Descartes, and Département de Physiologie, Hopital Necker Enfants Malades, F 75015, Paris, France
    J Biol Chem 283:4602-11. 2008
  10. ncbi Arterial stiffness and angiotensinogen gene in hypertensive patients and mutant mice
    Erwan Bozec
    Department of Pharmacology, Hôpital Européen Georges Pompidou and Institut National de la Santé et de la Recherche Médicale EMI 0107, Paris, France
    J Hypertens 22:1299-307. 2004

Collaborators

Detail Information

Publications34

  1. pmc Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice
    P Meneton
    Institut National de la Santé et de la Recherche Médicale INSERM U367, 17 Rue du Fer a Moulin, 75005 Paris, France
    Proc Natl Acad Sci U S A 98:2634-9. 2001
    ..They suggest that the kallikrein-kinin system could be involved in the development or progression of cardiovascular diseases...
  2. ncbi Comparative roles of the renal apical sodium transport systems in blood pressure control
    P Meneton
    INSERM U367, Paris, France
    J Am Soc Nephrol 11:S135-9. 2000
    ..The overall effect of NHE3 inactivation on BP may also involve absorptive defects in the intestine and colon, where the exchanger normally reabsorbs significant amounts of Na(+) and water...
  3. ncbi Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases
    Pierre Meneton
    Institut National de la Santé et de la Recherche Médicale U367, Département de Santé Publique et d Informatique Médicale, Faculté de Médecine Broussais Hôtel Dieu, Paris, France
    Physiol Rev 85:679-715. 2005
    ..Thus chronic exposure to a high-salt diet appears to be a major factor involved in the frequent occurrence of hypertension and cardiovascular diseases in human populations...
  4. ncbi Sodium and potassium handling by the aldosterone-sensitive distal nephron: the pivotal role of the distal and connecting tubule
    Pierre Meneton
    Unité 367 de l Institut National de la Santé et de la Recherche Médicale, 75005 Paris, France
    Am J Physiol Renal Physiol 287:F593-601. 2004
    ....
  5. ncbi Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors
    Sonia Bergaya
    Institut National de la Sante et de la Recherche Medicale, Unit 541, Hopital Lariboisiere, Paris, France
    Circ Res 94:1623-9. 2004
    ..In conclusion, this study demonstrates that the presence of functional AT2 receptors is necessary to observe the contribution of the vascular kinin-kallikrein system to flow-dependent dilation...
  6. ncbi Pendrin regulation in mouse kidney primarily is chloride-dependent
    Marion Vallet
    INSERM U652, IFR58, Institut des Cordeliers, Paris, France
    J Am Soc Nephrol 17:2153-63. 2006
    ..These results suggest that factors that are associated with changes in distal chloride delivery govern pendrin expression in the connecting tubule and cortical collecting duct...
  7. ncbi Inactivation of the Na-Cl co-transporter (NCC) gene is associated with high BMD through both renal and bone mechanisms: analysis of patients with Gitelman syndrome and Ncc null mice
    Laurence Nicolet-Barousse
    Departement de Physiologie, Hôpital Européen George Pompidou, Institut National de la Santé et de la Recherche Médicale INSERM U 652, IFR 58, Universite Paris V, Paris, France
    J Bone Miner Res 20:799-808. 2005
    ....
  8. ncbi Tissue kallikrein-deficient mice display a defect in renal tubular calcium absorption
    Nicolas Picard
    INSERM, Unité 652, and Institut Fédératif de Recherche 58, Paris, France
    J Am Soc Nephrol 16:3602-10. 2005
    ..TK deficiency had no effect on the renal abundance of distal Ca transporter mRNA. These data suggest that TK may be a physiologic regulator of RTCa transport, acting through a non-kinin-mediated mechanism...
  9. ncbi Defective ENaC processing and function in tissue kallikrein-deficient mice
    Nicolas Picard
    INSERM U872 Centre de Recherche des Cordeliers, Universite Paris 5, Faculté de Médecine René Descartes, and Département de Physiologie, Hopital Necker Enfants Malades, F 75015, Paris, France
    J Biol Chem 283:4602-11. 2008
    ..The results demonstrate that TK, like several other proteases, can activate ENaC in the kidney and the colon...
  10. ncbi Arterial stiffness and angiotensinogen gene in hypertensive patients and mutant mice
    Erwan Bozec
    Department of Pharmacology, Hôpital Européen Georges Pompidou and Institut National de la Santé et de la Recherche Médicale EMI 0107, Paris, France
    J Hypertens 22:1299-307. 2004
    ....
  11. doi Tissue kallikrein deficiency aggravates cardiac remodelling and decreases survival after myocardial infarction in mice
    Sandrine Pons
    INSERM U 652 872, CRC, IFR 58, Paris, France
    Eur J Heart Fail 10:343-51. 2008
    ..TK is involved in cardioprotection in the setting of acute myocardial ischaemia but its role in post-ischaemic heart failure (HF), a major cause of delayed mortality after myocardial infarction (MI), is unknown...
  12. doi Chronic potassium depletion increases adrenal progesterone production that is necessary for efficient renal retention of potassium
    Boutaïna Elabida
    UPMC Univ Paris 6 INSERM CNRS, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, Centre de Recherche des Cordeliers, Paris, France
    Kidney Int 80:256-62. 2011
    ..Thus, in males, a specific progesterone concentration profile induced by chronic potassium restriction regulates potassium balance...
  13. doi Evaluation of the agreement between guidelines and initial antihypertensive drug treatment using a national health care reimbursement database
    Pierre Meneton
    Institut National de la Sante et de la Recherche Medicale, Centre de Recherche des Cordeliers, Paris, France
    J Eval Clin Pract 18:623-9. 2012
    ....
  14. ncbi Role of tissue kallikrein in response to flow in mouse resistance arteries
    Sonia Bergaya
    Institut National de la Sante et de la Recherche Medicale INSERM, Unit 541, Hôpital Lariboisière and Inserm Unit 367, 17 Rue du Fer a Moulin, Paris, France
    J Hypertens 22:745-50. 2004
    ..We hypothesized that the vascular kinin-kallikrein system may be involved in shear stress signalling in small resistance arteries, which have a key role in the systemic regulation of blood pressure...
  15. ncbi Decreased flow-dependent dilation in carotid arteries of tissue kallikrein-knockout mice
    S Bergaya
    Institut National de la Sante et de la Recherche Medicale, Unit 541 Hôpital Lariboisière, Paris, France
    Circ Res 88:593-9. 2001
    ..This study demonstrates the active contribution of the vascular kallikrein-kinin system to one-third of the flow-dependent dilation response via activation of B(2) receptors coupled to endothelial NO release...
  16. doi Distinctive unhealthy eating pattern in free-living middle-aged hypertensives when compared with dyslipidemic or overweight patients
    Pierre Meneton
    Inserm U872, Centre de Recherche des Cordeliers, Paris, France
    J Hypertens 31:1554-63. 2013
    ..To evaluate habitual dietary intakes in patients with established hypertension, dyslipidemia and/or overweight...
  17. doi Health insurance coverage is the single most prominent socioeconomic factor associated with cardiovascular drug delivery in the French population
    Pierre Meneton
    Institut National de la Sante et de la Recherche Medicale, Unite 872, Centre de Recherche des Cordeliers, Paris, France
    J Hypertens 30:617-23. 2012
    ....
  18. ncbi Bone mineral measurements in mice: comparison of two devices
    Sami Kolta
    Rheumatology Department, Cochin Hospital, Assistance Publique, Hôpitaux de Paris René Descartes University, Paris, France
    J Clin Densitom 6:251-8. 2003
    ..We concluded that bone density and bone-density changes in mice can be measured precisely in vivo using the Hologic and Piximus devices; the latter being able to measure the whole body BMD with good precision...
  19. ncbi Altered renin synthesis and secretion in the kidneys of heterozygous mice with a null mutation in the TGF-beta(2) gene
    Laurence Pietri
    INSERM U367, Hopital Broussais, Paris, France
    Exp Nephrol 10:374-82. 2002
    ..These data suggest that TGF-beta(2) exerts an inhibitory effect on renin synthesis and release from the juxtaglomerular apparatuses...
  20. ncbi Genetic renal tubular disorders of renal ion channels and transporters
    P Meneton
    INSERM U367, Paris, France
    Semin Nephrol 21:81-93. 2001
    ....
  21. pmc Genetically increased angiotensin I-converting enzyme level and renal complications in the diabetic mouse
    W Huang
    Institut National de la Sante et de la Recherche Medicale, Unit 367, 17 Rue du Fer a Moulin, 75005 Paris, France
    Proc Natl Acad Sci U S A 98:13330-4. 2001
    ..Proteinuria was correlated to plasma ACE level in the three-copy diabetic mice. Thus, a modest genetic increase in ACE levels is sufficient to cause nephropathy in diabetic mice...
  22. doi High plasma aldosterone and low renin predict blood pressure increase and hypertension in middle-aged Caucasian populations
    P Meneton
    Inserm U872, Centre de Recherche des Cordeliers, Paris, France
    J Hum Hypertens 22:550-8. 2008
    ..03 and 0.05). These results reinforce the hypothesis that high plasma aldosterone and low plasma renin levels precede blood pressure increase and the occurrence of hypertension in middle-aged Caucasian populations...
  23. ncbi Cardiovascular phenotypes of kinin B2 receptor- and tissue kallikrein-deficient mice
    Fabien Trabold
    Departement de Pharmacologie, Faculte de Medecine Paris Sud, INSERM 00 01, Le Kremlin Bicetre, France
    Hypertension 40:90-5. 2002
    ..The phenotypic differences observed between TK-/- and B2-/- mice could be underlain by tissue kallikrein kinin-independent effect and/or kinin B1 receptor activation...
  24. ncbi Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome
    Johannes Loffing
    Department of Pharmacology and Toxicology, University of Lausanne, Rue du Bugnon 27, CH 1005 Lausanne
    J Am Soc Nephrol 15:2276-88. 2004
    ..Thus, loss of NCC leads to major structural remodeling of the renal distal tubule that goes along with marked changes in glomerular and tubular function, which may explain some of the clinical features of Gitelman's syndrome...
  25. doi Genetic deficiency in tissue kallikrein activity in mouse and man: effect on arteries, heart and kidney
    Anne Pizard
    INSERM U652 U872, Centre de Recherche des Cordeliers, 15 rue de l Ecole de Medecine, F 75006 Paris, France
    Biol Chem 389:701-6. 2008
    ..Potential clinical and therapeutic developments are discussed...
  26. ncbi Change in salt intake affects blood pressure of chimpanzees: implications for human populations
    Paul Elliott
    Department of Epidemiology and Public Health, Imperial College London, Faculty of Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
    Circulation 116:1563-8. 2007
    ..Effects of more modest alterations to sodium intakes in chimpanzees, akin to current efforts to lower sodium intakes in the human population, are unknown...
  27. ncbi Tissue kallikrein is involved in the cardioprotective effect of AT1-receptor blockade in acute myocardial ischemia
    Erij Messadi-Laribi
    INSERM U652 872, 15 rue de l Ecole de Medecine, 75270 Paris, France
    J Pharmacol Exp Ther 323:210-6. 2007
    ..Our results support the hypothesis of a coupling between AT2 receptors and kallikrein during AT1 receptor blockade, which plays a major role in cardioprotection...
  28. ncbi A second expressed kininogen gene in mice
    Edward G Shesely
    Hypertension and Vascular Research, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Physiol Genomics 26:152-7. 2006
    ..Conversely, in the kidney K2 is strongly expressed as both HMWK and LMWK, whereas K1 is not expressed as HMWK and expressed only very weakly as LMWK...
  29. ncbi Uterine artery structural and functional changes during pregnancy in tissue kallikrein-deficient mice
    Rob H P Hilgers
    Department of Pharmacology and Toxicology, Cardiovascular Research Institute Maastricht, Universiteit Maastricht, Netherlands
    Arterioscler Thromb Vasc Biol 23:1826-32. 2003
    ..We investigated whether TK deficiency blunts FID and alters chronic flow-related arterial structural and functional changes in resistance-sized muscular arteries...
  30. ncbi Transforming growth factor beta in cardiovascular development and function
    Mohamad Azhar
    Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    Cytokine Growth Factor Rev 14:391-407. 2003
    ..The evidence for TGFbeta activities during cardiovascular development and physiologic function will be given and areas which need further investigation will be discussed...
  31. ncbi Renin and kallikrein in connecting tubule of mouse
    Andreas Rohrwasser
    Department of Human Genetics, University of Utah, Health Sciences Center, Salt Lake City, Utah 84112, USA
    Kidney Int 64:2155-62. 2003
    ..Are the genes expressed in the same or in different cells of connecting tubule? Does this topography support the hypothesis that KLK-1 activates prorenin or is it more likely that it affords coordinated gene regulation?..
  32. ncbi Protective effects of high dietary potassium: nutritional and metabolic aspects
    Christian Demigne
    Metabolic Diseases and Micronutriments Unit, INRA Theix CRNH Clermont Ferrand, 63122 St Genes Champanelle, France
    J Nutr 134:2903-6. 2004
    ..The need to ensure a 2.5- to 3.5-g daily K+ supply from fruits and vegetables represents a strong rationale for the "5-10 servings per day" recommendations...
  33. pmc Proximal renal tubular acidosis in TASK2 K+ channel-deficient mice reveals a mechanism for stabilizing bicarbonate transport
    Richard Warth
    Institute of Physiology, Universitatsstrasse 31, 93053 Regensburg, Germany
    Proc Natl Acad Sci U S A 101:8215-20. 2004
    ..The consequences of the task2 gene inactivation in mice are reminiscent of the clinical manifestations seen in human proximal renal tubular acidosis syndrome...
  34. ncbi The sequential cleavage of membrane anchored pro-EGF requires a membrane serine protease other than kallikrein in rat kidney
    Sylvain M Le Gall
    Institut de Biochimie et Biophysique Moléculaire et Cellulaire CNRS UMR 8619, Université Paris XI Bât 430, 91405 Orsay Cedex, France
    Regul Pept 122:119-29. 2004
    ..By use of wild-type and knockout mice urines, we found that tissue kallikrein (TK) was not involved in the regulation of this processing...