Elie Azoulay

Summary

Affiliation: Medical ICU
Country: France

Publications

  1. doi request reprint Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality
    Jean Ralph Zahar
    Infection Control Unit, Necker University Hospital Paris, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 39:1886-95. 2011
  2. ncbi request reprint Decisions to forgo life-sustaining therapy in ICU patients independently predict hospital death
    Elie Azoulay
    Saint Louis Teaching Hospital, Medical ICU Department, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 29:1895-901. 2003
  3. ncbi request reprint Candida colonization of the respiratory tract and subsequent pseudomonas ventilator-associated pneumonia
    Elie Azoulay
    Medical ICU, Saint Louis Teaching Hospital, 1 Ave Claude Vellefaux, 75010 Paris, France
    Chest 129:110-7. 2006
  4. doi request reprint Postintensive care unit psychological burden in patients with chronic obstructive pulmonary disease and informal caregivers: A multicenter study
    Sandra De Miranda
    AP HP, Hopital Saint Louis, Medical ICU and Biostatistics Department, Paris, France
    Crit Care Med 39:112-8. 2011
  5. ncbi request reprint Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU stays
    Delphine Moreau
    Medical ICU, Saint Louis Teaching Hospital, 1 Ave Claude Vellefaux, 75010 Paris, France
    Chest 131:1735-41. 2007
  6. doi request reprint Molecular detection of respiratory viruses in immunocopromised ICU patients: incidence and meaning
    David Schnell
    AP HP, Hopital Saint Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France
    Respir Med 106:1184-91. 2012
  7. ncbi request reprint The prognosis of acute respiratory failure in critically ill cancer patients
    Elie Azoulay
    Medical Intensive Care Unit, Biostatistics Department, Saint Louis Hospital and Paris 7 University, Paris, France
    Medicine (Baltimore) 83:360-70. 2004
  8. ncbi request reprint Risk of post-traumatic stress symptoms in family members of intensive care unit patients
    Elie Azoulay
    Service de Reanimation Medicale, Hopital Saint Louis, Paris, France
    Am J Respir Crit Care Med 171:987-94. 2005
  9. ncbi request reprint Time course of organ dysfunction in thrombotic microangiopathy patients receiving either plasma perfusion or plasma exchange
    Michael Darmon
    Medical Intensive Care Unit, Assistance Publique Hopitaux de Paris, Saint Louis University Hospital, Paris, France
    Crit Care Med 34:2127-33. 2006
  10. doi request reprint Assessing burden in families of critical care patients
    Nancy Kentish-Barnes
    Medical Intensive Care Unit Department, AP HP, Hopital Saint Louis, Paris, France
    Crit Care Med 37:S448-56. 2009

Detail Information

Publications115 found, 100 shown here

  1. doi request reprint Outcomes in severe sepsis and patients with septic shock: pathogen species and infection sites are not associated with mortality
    Jean Ralph Zahar
    Infection Control Unit, Necker University Hospital Paris, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 39:1886-95. 2011
    ..We evaluated the respective influence of the causative pathogen and infection site on hospital mortality from severe sepsis related to community-, hospital-, and intensive care unit-acquired infections...
  2. ncbi request reprint Decisions to forgo life-sustaining therapy in ICU patients independently predict hospital death
    Elie Azoulay
    Saint Louis Teaching Hospital, Medical ICU Department, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 29:1895-901. 2003
    ..The objectives of this study were to describe the factors and mortality associated with DFLSTs and to evaluate the potential independent impact of DFLSTs on hospital mortality...
  3. ncbi request reprint Candida colonization of the respiratory tract and subsequent pseudomonas ventilator-associated pneumonia
    Elie Azoulay
    Medical ICU, Saint Louis Teaching Hospital, 1 Ave Claude Vellefaux, 75010 Paris, France
    Chest 129:110-7. 2006
    ..However, interactions between Candida and bacteria, particularly Pseudomonas, have been reported. Thus, Candida colonization of the respiratory tract may predispose to bacterial ventilator-associated pneumonia (VAP)...
  4. doi request reprint Postintensive care unit psychological burden in patients with chronic obstructive pulmonary disease and informal caregivers: A multicenter study
    Sandra De Miranda
    AP HP, Hopital Saint Louis, Medical ICU and Biostatistics Department, Paris, France
    Crit Care Med 39:112-8. 2011
    ....
  5. ncbi request reprint Platelet count decline: an early prognostic marker in critically ill patients with prolonged ICU stays
    Delphine Moreau
    Medical ICU, Saint Louis Teaching Hospital, 1 Ave Claude Vellefaux, 75010 Paris, France
    Chest 131:1735-41. 2007
    ..Thrombocytopenia is common in ICU patients. The objective of this study was to evaluate possible links between declining platelet counts early in the ICU stay and survival...
  6. doi request reprint Molecular detection of respiratory viruses in immunocopromised ICU patients: incidence and meaning
    David Schnell
    AP HP, Hopital Saint Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France
    Respir Med 106:1184-91. 2012
    ..Prospective single-center study to assess the sensitivity and clinical relevance of molecular testing for respiratory viruses in critically ill immunocompromised patients with acute respiratory failure (ARF)...
  7. ncbi request reprint The prognosis of acute respiratory failure in critically ill cancer patients
    Elie Azoulay
    Medical Intensive Care Unit, Biostatistics Department, Saint Louis Hospital and Paris 7 University, Paris, France
    Medicine (Baltimore) 83:360-70. 2004
    ..The impact of conventional mechanical ventilation on survival depends on the time from ICU admission to conventional mechanical ventilation and on the patient's response to noninvasive mechanical ventilation...
  8. ncbi request reprint Risk of post-traumatic stress symptoms in family members of intensive care unit patients
    Elie Azoulay
    Service de Reanimation Medicale, Hopital Saint Louis, Paris, France
    Am J Respir Crit Care Med 171:987-94. 2005
    ..Intensive care unit (ICU) admission of a relative is a stressful event that may cause symptoms of post-traumatic stress disorder (PTSD)...
  9. ncbi request reprint Time course of organ dysfunction in thrombotic microangiopathy patients receiving either plasma perfusion or plasma exchange
    Michael Darmon
    Medical Intensive Care Unit, Assistance Publique Hopitaux de Paris, Saint Louis University Hospital, Paris, France
    Crit Care Med 34:2127-33. 2006
    ..Few studies have investigated adults with thrombotic microangiopathy (TMA) requiring intensive care unit (ICU) admission, and the treatment remains controversial...
  10. doi request reprint Assessing burden in families of critical care patients
    Nancy Kentish-Barnes
    Medical Intensive Care Unit Department, AP HP, Hopital Saint Louis, Paris, France
    Crit Care Med 37:S448-56. 2009
    ..To provide critical care clinicians with information on validated instruments for assessing burden in families of critical care patients...
  11. ncbi request reprint Half the family members of intensive care unit patients do not want to share in the decision-making process: a study in 78 French intensive care units
    Elie Azoulay
    Intensive Care Unit of the Saint Louis Teaching Hospital and University of Paris 7, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 32:1832-8. 2004
    ....
  12. doi request reprint Unresponsive thrombotic thrombocytopenic purpura in critically ill adults
    Eric Mariotte
    Medical ICU, Saint Louis Hospital and Université Paris Diderot, Sorbonne Paris Cité, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 39:1272-81. 2013
    ..However, unresponsive thrombotic thrombocytopenic purpura (Un-TTP) still carries high morbidity and mortality rates, indicating a need for early specific treatments...
  13. ncbi request reprint One-day quantitative cross-sectional study of family information time in 90 intensive care units in France
    Thomas Fassier
    Intensive Care Unit of the Saint Louis Teaching Hospital and University of Paris 7, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 35:177-83. 2007
    ..Time spent informing families has been associated with effectiveness of information but has not been measured in specifically designed studies...
  14. ncbi request reprint Outcome of critically ill allogeneic hematopoietic stem-cell transplantation recipients: a reappraisal of indications for organ failure supports
    Frédéric Pène
    Medical Intensive Care Unit, Cochin Hospital, AP HP, Paris, France
    J Clin Oncol 24:643-9. 2006
    ....
  15. doi request reprint Survival in neutropenic patients with severe sepsis or septic shock
    Matthieu Legrand
    Medical Intensive Care Unit, AP HP, Saint Louis Hospital, Assistance Publique Hopitaux de Paris, and University of Paris, Paris, France
    Crit Care Med 40:43-9. 2012
    ..To determine whether the survival gains achieved in critically ill cancer patients in recent years exist in the subset with neutropenia and severe sepsis or septic shock...
  16. pmc Survival trends in critically ill HIV-infected patients in the highly active antiretroviral therapy era
    Isaline Coquet
    Service de Reanimation Medicale, AP HP, Hopital Saint Louis, 1 avenue Claude Vellefaux, Université Paris 7 Paris Diderot, UFR de Medecine, 75010 Paris, France
    Crit Care 14:R107. 2010
    ..Our objective was to assess whether highly active ART was associated with improved survival in critically ill HIV-infected patients...
  17. doi request reprint Predictors of noninvasive ventilation failure in patients with hematologic malignancy and acute respiratory failure
    Mélanie Adda
    AP HP, Hopital Saint Louis, Medical ICU, Paris, France
    Crit Care Med 36:2766-72. 2008
    ..However, failure of noninvasive ventilation may lead to an increased mortality...
  18. ncbi request reprint The ICU trial: a new admission policy for cancer patients requiring mechanical ventilation
    Lucien Lecuyer
    AP HP, Saint Louis Hospital, Medical ICU, Paris 7 University, Paris, France
    Crit Care Med 35:808-14. 2007
    ..Cancer patients requiring mechanical ventilation are widely viewed as poor candidates for intensive care unit (ICU) admission. We designed a prospective study evaluating a new admission policy titled The ICU Trial...
  19. doi request reprint Clinical assessment for identifying causes of acute respiratory failure in cancer patients
    David Schnell
    Medical Intensive Care Unit, Hoˆpital Saint Louis, Paris, France
    Eur Respir J 42:435-43. 2013
    ....
  20. ncbi request reprint Practices in non-neutropenic ICU patients with Candida-positive airway specimens
    Elie Azoulay
    Intensive Care Unit, Saint Louis Teaching Hospital, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 30:1384-9. 2004
    ..Design : Closed-item questionnaire with a clinical vignette...
  21. doi request reprint Prognostic contributions of the underlying inflammatory disease and acute organ dysfunction in critically ill patients with systemic rheumatic diseases
    Stanislas Faguer
    AP HP, Hopital Saint Louis, Medical ICU, Paris, France
    Eur J Intern Med 24:e40-4. 2013
    ..Knowledge about the clinical features, outcomes and predictors of short-term mortality in critically ill patients with systemic rheumatic disease (SRD) requires further characterization...
  22. pmc Acute kidney injury in patients with newly diagnosed high-grade hematological malignancies: impact on remission and survival
    Emmanuel Canet
    Medical Intensive Care Unit, Saint Louis University Hospital, Paris, France
    PLoS ONE 8:e55870. 2013
    ..Optimal chemotherapy with minimal toxicity is the main determinant of complete remission in patients with newly diagnosed hematological malignancies. Acute organ dysfunctions may impair the patient's ability to receive optimal chemotherapy...
  23. doi request reprint Increased nonbeneficial care in patients spending their birthday in the ICU
    Elie Azoulay
    Medical ICU, AP HP, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 38:1169-76. 2012
    ..Previous studies identified substantial subjective biases during end-of-life decision-making. We evaluated whether in-ICU patient's birthday influenced management decisions...
  24. ncbi request reprint Outcome of cancer patients considered for intensive care unit admission: a hospital-wide prospective study
    Guillaume Thiery
    Medical Intensive Care Unit, Saint Louis Teaching Hospital, 1 rue Claude Vellefaux, 75010 Paris, France
    J Clin Oncol 23:4406-13. 2005
    ..To evaluate the outcome of cancer patients considered for admission to the intensive care unit (ICU)...
  25. doi request reprint Important questions asked by family members of intensive care unit patients
    Vincent Peigne
    AP HP, Hopital Saint Louis, Medical ICU, Paris, France
    Crit Care Med 39:1365-71. 2011
    ..We aimed to develop a list of questions important for relatives of patients in the intensive care unit...
  26. doi request reprint Diagnostic strategy for hematology and oncology patients with acute respiratory failure: randomized controlled trial
    Elie Azoulay
    Medical Intensive Care Unit, Saint Louis Teaching Hospital, 75010 Paris, France
    Am J Respir Crit Care Med 182:1038-46. 2010
    ..Fiberoptic bronchoscopy with bronchoalveolar lavage (FO-BAL) is an invasive test that may cause respiratory deterioration. Recent noninvasive diagnostic tests may have modified the risk/benefit ratio of FO-BAL...
  27. doi request reprint Impact of adverse events on outcomes in intensive care unit patients
    Maite Garrouste Orgeas
    Medical Surgical ICU, Saint Joseph Hospital Network, Paris, France
    Crit Care Med 36:2041-7. 2008
    ..To examine the association between predefined adverse events (AE) (including nosocomial infections) and intensive care unit (ICU) mortality, controlling for multiple adverse events in the same patient and confounding variables...
  28. ncbi request reprint Family-physician interactions in the intensive care unit
    Elie Azoulay
    Medical ICU, Saint Louis Teaching Hospital, and Paris 7 University Paris, France
    Crit Care Med 32:2323-8. 2004
    ....
  29. doi request reprint Association between hypernatraemia acquired in the ICU and mortality: a cohort study
    Michael Darmon
    Medical Intensive Care Unit, Saint Louis University Hospital, APHP, 1 avenue Claude Vellefaux, Paris, France
    Nephrol Dial Transplant 25:2510-5. 2010
    ..The aim of this study is to describe the prevalence and outcomes of intensive care unit (ICU)-acquired hypernatraemia (IAH)...
  30. doi request reprint Health-related quality of life in family members of intensive care unit patients
    Virginie Lemiale
    FAMIREA Group Study, Saint Louis Teaching Hospital, Medical Intensive Care Unit and Biostatistics Department, Paris 7 University, Assistance Publique Hopitaux de Paris, France
    J Palliat Med 13:1131-7. 2010
    ..The objective of this study was to evaluate health-related quality of life (HRQOL) in relatives of patients 90 days after ICU discharge or death...
  31. doi request reprint Safety of intrahospital transport in ventilated critically ill patients: a multicenter cohort study*
    Carole Schwebel
    Medical ICU, Albert Michallon Teaching Hospital, University Joseph Fourier, Grenoble, France
    Crit Care Med 41:1919-28. 2013
    ..To describe intrahospital transport complications in critically ill patients receiving invasive mechanical ventilation...
  32. ncbi request reprint Outcomes of critically ill patients with hematologic malignancies: prospective multicenter data from France and Belgium--a groupe de recherche respiratoire en réanimation onco-hématologique study
    Elie Azoulay
    Hopital Saint Louis, Medical ICU, Paris, France
    J Clin Oncol 31:2810-8. 2013
    ..CONCLUSION Critically ill patients with hematologic malignancies have good survival, disease control, and post-ICU HRQOL. Earlier ICU admission is associated with better survival. ..
  33. ncbi request reprint Junior versus senior physicians for informing families of intensive care unit patients
    Delphine Moreau
    Service de Reanimation Medicale, Hopital Saint Louis, Paris, France
    Am J Respir Crit Care Med 169:512-7. 2004
    ..9 vs. 34.4%, p = 0.004). Specialty residents, if given opportunities for acquiring experience, can become proficient in communicating with families and share this task with senior physicians...
  34. ncbi request reprint Outcomes in critically ill cancer patients with septic shock of pulmonary origin
    Etienne de Montmollin
    Medical Intensive Care Unit, Saint Louis Teaching Hospital, Paris, France
    Shock 39:250-4. 2013
    ..Delayed ICU management is an independent predictor of death. Studies assessing survival benefits from early ICU management are warranted...
  35. doi request reprint Impact of a recent chemotherapy on the duration and intensity of the norepinephrine support during septic shock
    David Schnell
    Medical ICU, AP HP, Hôpital Saint Louis and UFR de Médecine, University Paris 7 Paris Diderot, Paris, France
    Shock 39:138-43. 2013
    ..Mortality was not different in cancer and noncancer patients with septic shock...
  36. pmc Diagnostic accuracy of procalcitonin in critically ill immunocompromised patients
    Nicolas Bele
    AP HP, Hopital Saint Louis, Medical ICU Department, 75010 Paris, France
    BMC Infect Dis 11:224. 2011
    ..Recognizing infection is crucial in immunocompromised patients with organ dysfunction. Our objective was to assess the diagnostic accuracy of procalcitonin (PCT) in critically ill immunocompromised patients...
  37. doi request reprint Prognostic significance of acute renal injury in acute tumor lysis syndrome
    Michael Darmon
    Assistance Publique des Hopitaux de Paris, Medical Intensive Care Unit, Saint Louis University Hospital, Paris, France
    Leuk Lymphoma 51:221-7. 2010
    ..64-54.66; p = 0.006), compared to patients without renal injury. Our study suggests that in patients with ATLS, ICU management when acute renal injury is present is associated with higher short- and long-term mortality...
  38. ncbi request reprint Management and treatment results in patients with acute promyelocytic leukaemia (APL) not enrolled in clinical trials
    Jean Baptiste Micol
    Department of Hematology and EA3518, Hopital Saint Louis Assistance Publique Hopitaux de Paris, University Paris Diderot, Paris, France
    Eur J Cancer 50:1159-68. 2014
    ..To address this issue, we reviewed all APL patients referred to the Hospital Saint-Louis within the 2000-2010 period, with a special focus on inclusion in recruiting trials...
  39. doi request reprint Noninvasive mechanical ventilation in patients having declined tracheal intubation
    Elie Azoulay
    Medical ICU, Saint Louis Hospital AP HP, Medical ICU, Faculte de Medecine, Universite Paris Diderot, Sorbonne Paris Cité, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 39:292-301. 2013
    ..The aim of our study was to report outcomes after NIV in patients with a do-not-intubate (DNI) order...
  40. doi request reprint Causes and risk factors of death in patients with thrombotic microangiopathies
    Vincent Peigne
    AP HP, Hôpital Saint Louis Medical ICU, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 38:1810-7. 2012
    ..Although plasma therapy of thrombotic micro-angiopathies (TMAs) has dramatically improved survival, the outcome remains fatal in up to 15 % of patients. We investigated the causes and risk factors of death in patients with TMA...
  41. ncbi request reprint Family participation in care to the critically ill: opinions of families and staff
    Elie Azoulay
    Service de Reanimation Medicale, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 29:1498-504. 2003
    ..Allowing family members to participate in the care of patients in intensive care units (ICUs) may improve the quality of their experience. No previous study has investigated opinions about family participation in ICUs...
  42. ncbi request reprint Opinions about surrogate designation: a population survey in France
    Elie Azoulay
    The French Famirea Study Group, Intensive Care Unit of the Saint Louis Teaching Hospital, University Paris 7, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 31:1711-4. 2003
    ..The objective of this study was to determine whether people who are not yet ill are ready to accept surrogate designation. Attitudes toward family participation in care were explored also...
  43. ncbi request reprint Should dialysis be offered to cancer patients with acute kidney injury?
    Michael Darmon
    Medical Intensive Care Unit, Saint Louis University Hospital, Assistance Publique des Hôpitaux de Paris and Paris VII University, 1 av Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 33:765-72. 2007
    ....
  44. doi request reprint Continued survival gains in recent years among critically ill myeloma patients
    Vincent Peigne
    Medical ICU, AP HP, Hopital Saint Louis, Paris, France
    Intensive Care Med 35:512-8. 2009
    ..Therapeutic advances have improved survival in patients with myeloma (MM) over the past decade. We investigated whether survival has also improved in critically ill myeloma patients...
  45. ncbi request reprint Prevalence and factors of intensive care unit conflicts: the conflicus study
    Elie Azoulay
    AP HP, Hopital Saint Louis, Medical ICU, University Paris 7 Paris Diderot, UFR de Medecine, 1 avenue Claude Vellefaux, 75010 Paris, France
    Am J Respir Crit Care Med 180:853-60. 2009
    ..Many sources of conflict exist in intensive care units (ICUs). Few studies recorded the prevalence, characteristics, and risk factors for conflicts in ICUs...
  46. doi request reprint End-of-life practices in 282 intensive care units: data from the SAPS 3 database
    Elie Azoulay
    Service de Reanimation Medicale, Hôpital Saint Louis et Université Paris 7, Assistance Publique, Hopitaux de Paris, Paris, France
    Intensive Care Med 35:623-30. 2009
    ..To report incidence and characteristics of decisions to forgo life-sustaining therapies (DFLSTs) in the 282 ICUs who contributed to the SAPS3 database...
  47. doi request reprint Surrogate decision makers for incompetent ICU patients: a European perspective
    Alexandre Lautrette
    Services de Réanimation Médicale, Hopital Saint Louis, Paris, France
    Curr Opin Crit Care 14:714-9. 2008
    ..Even though legitimacy of surrogates is now recognized by physicians, patients' management must take into account new legislations emphasizing patients' autonomy all over Europe...
  48. ncbi request reprint Determinants of postintensive care unit mortality: a prospective multicenter study
    Elie Azoulay
    Medical ICU, Hopital Saint Louis, Paris, France
    Crit Care Med 31:428-32. 2003
    ..We investigated determinants of post-ICU mortality, with special attention to this factor...
  49. ncbi request reprint Acute monocytic leukemia presenting as acute respiratory failure
    Elie Azoulay
    Medical Intensive Care Unit, Hematology Department, Saint Louis Teaching Hospital, Paris 7 University, France
    Am J Respir Crit Care Med 167:1329-33. 2003
    ....
  50. ncbi request reprint Ability of family members to predict patient's consent to critical care research
    Magali Ciroldi
    Medical Intensive Care Unit, AP HP, Saint Louis Teaching Hospital, Paris 7 University, Paris, France
    Intensive Care Med 33:807-13. 2007
    ..The accuracy with which surrogates consent to research on behalf of patients has not been evaluated in the intensive care unit (ICU)...
  51. ncbi request reprint Improved survival of critically ill cancer patients with septic shock
    Jérôme Larché
    Medical ICU of the Saint Louis Teaching Hospital and Paris 7 University, Assistance Publique Hopitaux de Paris, 1 av Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 29:1688-95. 2003
    ..To identify predictors of 30-day mortality in critically ill cancer patients with septic shock...
  52. doi request reprint Renal perfusion assessment by renal Doppler during fluid challenge in sepsis
    David Schnell
    Réanimation Médicale, Hopital Saint Louis, Assistance Publique Hopitaux de Paris, Paris, France
    Crit Care Med 41:1214-20. 2013
    ..To assess renal resistive index variations in response to fluid challenge...
  53. ncbi request reprint Post-ICU mortality in critically ill infected patients: an international study
    Elie Azoulay
    Intensive Care Unit, Saint Louis Hospital, Paris 7 University, 1 Avenue Claude, Vellefaux, 75010 Paris, France
    Intensive Care Med 31:56-63. 2005
    ..To determine the incidence and risk factors for post-ICU mortality in patients with infection...
  54. doi request reprint Central neurological complications in critically ill patients with malignancies
    Stephane Legriel
    Medical Intensive Care Unit, AP HP, Hopital Saint Louis, 75010 Paris, France
    Intensive Care Med 36:232-40. 2010
    ..To determine outcomes in critically ill patients hospitalized in the ICU for central neurological complications of cancer...
  55. doi request reprint Risk factors for pneumonia in immunocompromised patients with influenza
    David Schnell
    AP HP, Hopital Saint Louis, Medical ICU, 1 avenue Claude Vellefaux, 75010 Paris, France
    Respir Med 104:1050-6. 2010
    ..Immunocompromised patients with influenza are at higher risk of pneumonia and death. However, risk factors for progression to pneumonia still need evaluation...
  56. ncbi request reprint Diagnostic bronchoscopy in hematology and oncology patients with acute respiratory failure: prospective multicenter data
    Elie Azoulay
    Intensive Care Unit, Saint Louis Teaching Hospital, Paris, France
    Crit Care Med 36:100-7. 2008
    ..To describe the diagnostic yields of test strategies with and without fiberoptic bronchoscopy and bronchoalveolar lavage (FO-BAL), as well as outcomes, in cancer patients with acute respiratory failure (ARF)...
  57. ncbi request reprint Outcomes in critically ill chronic lymphocytic leukemia patients
    Aliénor Xhaard
    Bone Marrow Transplant Unit, AP HP, Saint Louis University Hospital, Paris, France
    Support Care Cancer 21:1885-91. 2013
    ..The aims of this study were to assess the prognosis of critically ill patients with chronic lymphocytic leukemia (CLL) and to evaluate risk factors for hospital mortality...
  58. ncbi request reprint Norepinephrine plus dobutamine versus epinephrine alone for management of septic shock: a randomised trial
    Djillali Annane
    Raymond Poincaré Hospital AP HP, University of Versailles Saint Quentin, PRES UniverSud, Paris, France
    Lancet 370:676-84. 2007
    ..However, no large comparative trial has yet been done. We aimed to compare the efficacy and safety of norepinephrine plus dobutamine (whenever needed) with those of epinephrine alone in septic shock...
  59. doi request reprint Intensive care unit management of patients with newly diagnosed acute myeloid leukemia with no organ failure
    Etienne Lengline
    Medical ICU, Hopital Saint Louis, AP HP and UFR de Médecine, University Paris 7 Paris Diderot, Paris, France
    Leuk Lymphoma 53:1352-9. 2012
    ..5 [2-9] days) and decreased ICU survival (65% vs. 79%). Direct admission to the ICU of patients with high-risk AML with physiological disturbances but no organ dysfunction is associated with improved outcomes...
  60. doi request reprint Systemic antifungal therapy in critically ill patients without invasive fungal infection*
    Elie Azoulay
    Paris 7 University, EA, Saint Louis Hospital, Paris, France
    Crit Care Med 40:813-22. 2012
    ..To determine the number of adult or pediatric intensive care unit patients without documented invasive fungal infection who receive systemic antifungal therapy...
  61. doi request reprint Efficacy and safety of first-line rituximab in severe, acquired thrombotic thrombocytopenic purpura with a suboptimal response to plasma exchange. Experience of the French Thrombotic Microangiopathies Reference Center
    Antoine Froissart
    Service d Hématologie Clinique et de Thérapie Cellulaire, AP HP, Groupe Hospitalier Pitie Salpetriere, UPMC Univ Paris 6, Paris, France
    Crit Care Med 40:104-11. 2012
    ..To assess the efficacy and safety of rituximab in adults responding poorly to standard treatment for severe autoimmune thrombotic thrombocytopenic purpura...
  62. doi request reprint Qualitative research: adding drive and dimension to clinical research
    Katerina Rusinová
    FAMIREA Study Group, Assistance Publique Hopitaux de Paris, Saint Louis Teaching Hospital, Medical Intensive Care Unit, Paris, France
    Crit Care Med 37:S140-6. 2009
    ..To illustrate the effectiveness of combining different research methods, we will refer to recent qualitative studies conducted in the intensive care unit...
  63. doi request reprint Use of N-terminal pro-brain natriuretic peptide to detect cardiac origin in critically ill cancer patients with acute respiratory failure
    Aurélie Lefebvre
    Service de Reanimation Medicale, Hopital Saint Louis, AP HP, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 34:833-9. 2008
    ..To assess the accuracy of plasma N-terminal-pro-B-type natriuretic peptide concentrations (NT-proBNP) as a diagnostic tool to recognize acute respiratory failure (ARF) of cardiac origin...
  64. ncbi request reprint Burnout syndrome in critical care nursing staff
    Marie Cecile Poncet
    Medical ICU, Saint Louis Hospital and Paris 7 University, Assistance Publique, Hopitaux de Paris, Paris, France
    Am J Respir Crit Care Med 175:698-704. 2007
    ..Burnout syndrome (BOS) associated with stress has been documented in health care professionals in many specialties. The intensive care unit (ICU) is a highly stressful environment. Little is known about BOS in critical care nursing staff...
  65. ncbi request reprint Having a loved one in the ICU: the forgotten family
    Matthieu Schmidt
    Universite Paris 6 Pierre et Marie Curie, Paris, France
    Curr Opin Crit Care 18:540-7. 2012
    ..An appreciation of the post-ICU burden for family members, as well as the ways to prevent and minimize their symptoms of stress, anxiety, and depression...
  66. doi request reprint The spectrum of lung involvement in collagen vascular-like diseases following allogeneic hematopoietic stem cell transplantation: report of 6 cases and review of the literature
    Anne Bergeron
    Service de Pneumologie, Hopital Saint Louis, Universite Paris 7, UFR Denis Diderot, Paris, France
    Medicine (Baltimore) 90:146-57. 2011
    ..These lung manifestations had poor prognoses. Further studies are needed to determine the optimal therapy for these complications...
  67. pmc Clinical features of H1N1 2009 infection in critically ill immunocompromised patients
    Laurent Camous
    Medical Intensive Care Unit, Saint Louis University Hospital, APHP, 1 avenue Claude Vellefaux, Paris, France
    Crit Care 14:139. 2010
    ..Half of the patients received long-term steroid therapy. Disease was characterized by a clinical picture similar to that of non-immunocompromised patients but with prolonged course and higher mortality...
  68. ncbi request reprint Care at the end of life in critically ill patients: the European perspective
    Thomas Fassier
    Medical Intensive Care Unit, Saint Louis Teaching Hospital and Paris 7 University, Paris, France
    Curr Opin Crit Care 11:616-23. 2005
    ..The aim of this review is to provide insight into the decisions to forego life sustaining therapies and end-of-life care in Europe...
  69. ncbi request reprint Clinical picture of Pneumocystis jiroveci pneumonia in cancer patients
    Guillaume Bollée
    Medical Intensive Care Unit, Assistance Publique, Hopitaux de Paris, Saint Louis Teaching Hospital, Paris, France
    Chest 132:1305-10. 2007
    ..Pneumocystis pneumonia (PCP) is common in patients with HIV infection but may also occur in patients with other causes of immunodeficiency, including hematologic and solid malignancies...
  70. ncbi request reprint Impact of neutropenia duration on short-term mortality in neutropenic critically ill cancer patients
    Michael Darmon
    Medical Intensive Care Unit, Saint Louis University Hospital and Paris 7 University, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 28:1775-80. 2002
    ..To identify predictors of 30-day mortality and to assess the impact of neutropenia recovery (NR) on 30-day mortality in critically ill cancer patients (CICPs)...
  71. doi request reprint Outcomes of mechanically ventilated hematology patients with invasive pulmonary aspergillosis
    Gaston Burghi
    AP HP, Hopital Saint Louis, Medical ICU, University Paris 7 Paris Diderot, UFR de Medecine, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 37:1605-12. 2011
    ..We report outcomes in hematology patients given mechanical ventilation (MV) with IPA...
  72. ncbi request reprint Polymerase chain reaction for diagnosing pneumocystis pneumonia in non-HIV immunocompromised patients with pulmonary infiltrates
    Elie Azoulay
    Service de Reanimation Medicale, Hopital Saint Louis, 1 avenue Claude Vellefaux, Paris, France
    Chest 135:655-61. 2009
    ..Pneumocystis jiroveci polymerase chain reaction (PCR) has higher sensitivity than conventional stains but cannot distinguish colonization from infection...
  73. pmc Acute respiratory failure in kidney transplant recipients: a multicenter study
    Emmanuel Canet
    Medical Intensive Care Unit and Biostatistics Departments, Saint Louis Teaching Hospital, 1 avenue Claude Vellefaux, Paris F 75010, France
    Crit Care 15:R91. 2011
    ..Data on pulmonary complications in renal transplant recipients are scarce. The aim of this study was to evaluate acute respiratory failure (ARF) in renal transplant recipients...
  74. ncbi request reprint Is methicillin resistance associated with a worse prognosis in Staphylococcus aureus ventilator-associated pneumonia?
    Jean Ralph Zahar
    Department of Microbiology, Necker Teaching Hospital, Paris, France
    Clin Infect Dis 41:1224-31. 2005
    ....
  75. pmc Evaluating mortality in intensive care units: contribution of competing risks analyses
    Matthieu Resche-Rigon
    Biostatistics Department, Saint Louis Teaching Hospital Assistance Publique Hôpitaux de Paris, 1 avenue Claude Vellefaux, Paris, 75010, France
    Crit Care 10:R5. 2006
    ..To address these issues, we exemplified the usefulness of standard competing risks methods; namely, cumulative incidence function (CIF) curves and the Fine and Gray model...
  76. doi request reprint Human immunodeficiency virus-associated thrombotic microangiopathies: clinical characteristics and outcome according to ADAMTS13 activity
    S Malak
    Service d Hématologie et de Thérapie Cellulaire, AP HP, Hôpital Saint Antoine and UPMC Université Paris 06, Paris, France
    Scand J Immunol 68:337-44. 2008
    ..04). In conclusion, HIV-associated TMA with severe ADAMTS13 deficiency have less AIDS-related complications and a higher CD4(+) T cell count. TMA prognosis is better and comparable to this of idiopathic forms...
  77. ncbi request reprint Infectious diseases as a trigger in thrombotic microangiopathies in intensive care unit (ICU) patients?
    Paul Coppo
    Department of Critical Care Medicine, Hôpital Saint Louis and University of Paris VII, 1 rue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 29:564-9. 2003
    ..We conducted a descriptive, retrospective study including all TMA adult patients admitted to our ICU, with a particular interest in infectious episodes as a trigger of TMA...
  78. doi request reprint Etiologies and outcome of acute respiratory failure in HIV-infected patients
    Francois Barbier
    Medical ICU and Infectious Disease Department, AP HP, Hopital Saint Louis, 1 avenue Claude Vellefaux, 75010, Paris, France
    Intensive Care Med 35:1678-86. 2009
    ..To assess the etiologies and outcome of acute respiratory failure (ARF) in HIV-infected patients over the first decade of combination antiretroviral therapy (ART) use...
  79. ncbi request reprint Diagnostic strategy in cancer patients with acute respiratory failure
    Elie Azoulay
    Service de Reanimation Medicale, Hôpital Saint Louis et Université Paris 7, Paris, France
    Intensive Care Med 32:808-22. 2006
    ..The most recent literature is reviewed, and emphasis is placed on current controversies, most notably the risk/benefit ratio of fiberoptic bronchoscopy and BAL in patients with severe hypoxemia...
  80. ncbi request reprint Communication with family members of patients dying in the intensive care unit
    Elie Azoulay
    Service de Réanimation Médicale Hôpital Saint Louis, Paris, France
    Curr Opin Crit Care 9:545-50. 2003
    ..The need for family-centered care and for a better communication within the patient-family-caregiver trio is also highlighted...
  81. ncbi request reprint Impact of unplanned extubation and reintubation after weaning on nosocomial pneumonia risk in the intensive care unit: a prospective multicenter study
    Arnaud de Lassence
    Medical ICU, Avicenne Hospital, Bobigny, France
    Anesthesiology 97:148-56. 2002
    ....
  82. pmc Clinical review: specific aspects of acute renal failure in cancer patients
    Michael Darmon
    Assistance Publique des Hopitaux de Paris, Saint Louis University Hospital, Medical ICU, Paris, France
    Crit Care 10:211. 2006
    ....
  83. ncbi request reprint Influence of gender on the outcome of severe sepsis: a reappraisal
    Christophe Adrie
    Medical Surgical ICU, Hopital Delafontaine, 2, rue du Dr Delafontaine, 93205 Sant Denis, France
    Chest 132:1786-93. 2007
    ..The influence of gender on survival of patients with severe sepsis is unclear. Earlier studies suggested better survival in women, possibly related to the sex-steroid profile...
  84. pmc Model for predicting short-term mortality of severe sepsis
    Christophe Adrie
    Medical Surgical Intensive Care Unit, Delafontaine Hospital, 93205 Saint Denis, France
    Crit Care 13:R72. 2009
    ..To establish a prognostic model for predicting 14-day mortality in ICU patients with severe sepsis overall and according to place of infection acquisition and to sepsis episode number...
  85. doi request reprint Selected medical errors in the intensive care unit: results of the IATROREF study: parts I and II
    Maite Garrouste-Orgeas
    Service de Réanimation medico chirurgicale, Groupe Hospitalier Paris Saint Joseph, 185 rue Raymond Losserand, 75014 Paris, France
    Am J Respir Crit Care Med 181:134-42. 2010
    ..Identifying medical errors (MEs) that serve as indicators for iatrogenic risk is crucial for purposes of reporting and prevention...
  86. ncbi request reprint Impact of a family information leaflet on effectiveness of information provided to family members of intensive care unit patients: a multicenter, prospective, randomized, controlled trial
    Elie Azoulay
    Intensive Care Department, Saint Louis Teaching Hospital, Paris 7 University, France
    Am J Respir Crit Care Med 165:438-42. 2002
    ..01). These results indicate that ICU caregivers should consider using an FIL to improve the effectiveness of the information they impart to families...
  87. doi request reprint Critical care management of cancer patients: cause for optimism and need for objectivity
    Michael Darmon
    Medical ICU, Saint Louis University Hospital, APHP, Paris, France
    Curr Opin Oncol 21:318-26. 2009
    ..This review discusses current outcomes of critically ill cancer patients and recent insights into prognostic factors. Persistent areas of uncertainty are emphasized...
  88. ncbi request reprint Is there a place for granulocyte colony-stimulating factor in non-neutropenic critically ill patients?
    Elie Azoulay
    Intensive Care Unit, Saint Louis Teaching Hospital, 1 avenue Claude Vellefaux, 75010 Paris, France
    Intensive Care Med 30:10-7. 2004
    ..This variability should be taken into account when designing studies on the use of G-CSF in ICU-patients. Studies are still needed to identify the subset of patients who may benefit from G-CSF therapy...
  89. ncbi request reprint Palivizumab treatment of respiratory syncytial virus infection after allogeneic hematopoietic stem cell transplantation
    Flore Sicre de Fontbrune
    Hematologie Greffe, Universite Paris 7, Assistance Publique Hopitaux de Paris, Hopital Saint Louis, Paris, France
    Clin Infect Dis 45:1019-24. 2007
    ..Palivizumab did not prevent progression to lower respiratory infection and had no impact on the overall survival rate...
  90. ncbi request reprint Clinically documented pleural effusions in medical ICU patients: how useful is routine thoracentesis?
    Muriel Fartoukh
    Medical and Respiratory Intensive Care Unit, Antoine Béclère Teaching Hospital, Paris, France
    Chest 121:178-84. 2002
    ..To assess the impact of routine thoracentesis on diagnostic assessment and therapeutic measures in patients with clinically documented pleural effusions...
  91. ncbi request reprint Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count, and mild renal involvement
    Paul Coppo
    Service d Hématologie et Faculté de Médecine, Hopital Saint Antoine, Paris, France
    Medicine (Baltimore) 83:233-44. 2004
    ..Indeed, apparently idiopathic thrombotic thrombocytopenic purpura may be considered a specific autoimmune disease...
  92. ncbi request reprint Excess risk of death from intensive care unit-acquired nosocomial bloodstream infections: a reappraisal
    Maite Garrouste-Orgeas
    Medical Surgical Intensive Care Unit, Saint Joseph Hospital, Paris, France corrected
    Clin Infect Dis 42:1118-26. 2006
    ..We investigated whether ICU-acquired BSI increased mortality (by > or = 10%) after adjustment for severity of infection at ICU admission and during the pre-BSI stay...
  93. ncbi request reprint Burnout syndrome among critical care healthcare workers
    Nathalie Embriaco
    Intensive Care Unit, Saint Louis and Sainte Marguerite Teaching Hospitals, Assistance Publique Hopitaux de Paris, University Paris 7, Paris and Assistance Publique, Hopitaux de Marseille, Marseille, France
    Curr Opin Crit Care 13:482-8. 2007
    ..Because ICUs are characterized by a high level of work-related stress, a factor known to increase the risk of burnout syndrome, we sought to review the available literature on burnout syndrome in ICU healthcare workers...
  94. ncbi request reprint Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock
    Djillali Annane
    Service de Reanimation Medicale, Hopital Raymond Poincare, 104 Blvd Raymond Poincaré, 92380 Garches, France
    JAMA 288:862-71. 2002
    ..Septic shock may be associated with relative adrenal insufficiency. Thus, a replacement therapy of low doses of corticosteroids has been proposed to treat septic shock...
  95. ncbi request reprint Tracheostomy does not improve the outcome of patients requiring prolonged mechanical ventilation: a propensity analysis
    Christophe Clec'h
    Intensive Care Unit, Avicenne Teaching Hospital, 125 route de Stalingrad, 93000 Bobigny, France
    Crit Care Med 35:132-8. 2007
    ..To examine the association between the performance of a tracheostomy and intensive care unit and postintensive care unit mortality, controlling for treatment selection bias and confounding variables...
  96. ncbi request reprint Prognosis of lung cancer patients with life-threatening complications
    Marcio Soares
    Instituto Nacional de Cancer, Centro de Tratamento Intensivo, 10 Andar Pça Cruz Vermelha, 23, Rio de Janeiro, Brazil
    Chest 131:840-6. 2007
    ..The aims of this study were to determine hospital mortality and to identify risk factors for death in a large cohort of critically ill patients...
  97. ncbi request reprint Does catheter-associated urinary tract infection increase mortality in critically ill patients?
    Christophe Clec'h
    Medical Surgical Intensive Care Unit, Avicenne Teaching Hospital, Bobigny, France
    Infect Control Hosp Epidemiol 28:1367-73. 2007
    ..To produce an accurate estimate of the association between catheter-associated urinary tract infection (UTI) and intensive care unit (ICU) and hospital mortality, controlling for major confounding factors...
  98. ncbi request reprint Body mass index. An additional prognostic factor in ICU patients
    Maite Garrouste-Orgeas
    Service de Reanimation Polyvalente, Hopital Saint Joseph, 185 rue Raymond Losserand, 75014 Paris, France
    Intensive Care Med 30:437-43. 2004
    ..To examine the association between body mass index (BMI) and mortality in adult intensive care unit (ICU) patients. DESIGN. A prospective multi-center study...
  99. ncbi request reprint Pneumothorax in the intensive care unit: incidence, risk factors, and outcome
    Arnaud de Lassence
    Medical Intensive Care Unit, Assistance Publique Hopitaux de Paris, Louis Mourier Teaching Hospital, Colombes, France
    Anesthesiology 104:5-13. 2006
    ..The risk factors and outcomes of critically ill patients with iatrogenic pneumothorax (IP) have not been studied in a large unselected intensive care unit (ICU) population...
  100. ncbi request reprint Epidemiology and economic evaluation of severe sepsis in France: age, severity, infection site, and place of acquisition (community, hospital, or intensive care unit) as determinants of workload and cost
    Christophe Adrie
    Medical Surgical ICU, Delafontaine Hospital, Saint Denis, France
    J Crit Care 20:46-58. 2005
    ..Severe sepsis is a leading cause of death in critically ill patients. We evaluated cost and workload according to infection site, place and time of acquisition, and severity...
  101. ncbi request reprint Intensive care in patients with newly diagnosed malignancies and a need for cancer chemotherapy
    Michael Darmon
    Medical Intensive Care Unit, Saint Louis University Hospital and Paris 7 University, France
    Crit Care Med 33:2488-93. 2005
    ..Patients with newly diagnosed cancer responsible for organ failures may require intensive care unit (ICU) admission and immediate chemotherapy. Outcomes in this population have not been studied...