Eve Maubec

Summary

Country: France

Publications

  1. doi request reprint Familial melanoma: clinical factors associated with germline CDKN2A mutations according to the number of patients affected by melanoma in a family
    Eve Maubec
    INSERM Institut National de Santé et de Recherche Médicale, Genetic Variation and Human Diseases Unit U946, Paris, France
    J Am Acad Dermatol 67:1257-64. 2012
  2. doi request reprint Characteristics of the coexistence of melanoma and renal cell carcinoma
    Eve Maubec
    National Institute of Health and Medical Research, Paris, France
    Cancer 116:5716-24. 2010
  3. ncbi request reprint Mixed nonseminomatous germ cell tumor presenting as a subcutaneous tissue mass
    Eve Maubec
    Institut Gustave Roussy, Villejuif, Paris, France
    Am J Dermatopathol 28:523-5. 2006
  4. ncbi request reprint F-18 fluorodeoxy-D-glucose positron emission tomography scan in the initial evaluation of patients with a primary melanoma thicker than 4 mm
    Eve Maubec
    Department of Dermatology, Institut Gustave Roussy, Villejuif Cedex, France
    Melanoma Res 17:147-54. 2007
  5. doi request reprint Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin
    Eve Maubec
    Hopital Bichat, Service de Dermatologie, 46 rue Henri Huchard, Paris, cedex 75877, France
    J Clin Oncol 29:3419-26. 2011
  6. pmc Pregnancy promotes melanoma metastasis through enhanced lymphangiogenesis
    Kiarash Khosrotehrani
    Universite Pierre et Marie Curie, University Paris 06, Paris, France
    Am J Pathol 178:1870-80. 2011
  7. ncbi request reprint Mature cytotoxic CD56(bright)/CD16(+) natural killer cells can infiltrate lymph nodes adjacent to metastatic melanoma
    Meriem Messaoudene
    Authors Affiliations Inserm U1016, CNRS UMR 8104, Institut Cochin APHP, Department of Dermatology, Hospital Cochin, University Paris Descartes APHP, Department of Dermatology APHP, Department of Surgery, Hospital Bichat, University Paris Diderot Surgery Department, Institut Curie, rue d Ulm Paris Hospital Foch, Suresnes Centre de Recherche des Cordeliers, 15 rue de l école de médecine and INSERM U1015 INSERM, Institut Gustave Roussy, Villejuif, Paris, France
    Cancer Res 74:81-92. 2014
  8. doi request reprint Progressive upregulation of PD-1 in primary and metastatic melanomas associated with blunted TCR signaling in infiltrating T lymphocytes
    Maxime Chapon
    Institut Cochin, INSERM, U1016, Paris, France
    J Invest Dermatol 131:1300-7. 2011
  9. pmc Distinct merkel cell polyomavirus molecular features in tumour and non tumour specimens from patients with merkel cell carcinoma
    Hélène C Laude
    Universite Paris Descartes, EA1833, Paris, France
    PLoS Pathog 6:e1001076. 2010
  10. doi request reprint Sentinel lymph node biopsy or nodal observation in melanoma: a prospective study of patient choices
    Florent Grange
    Service de Dermatologie, Hopital Robert Debre, Reims, France
    Dermatol Surg 37:199-206. 2011

Collaborators

Detail Information

Publications20

  1. doi request reprint Familial melanoma: clinical factors associated with germline CDKN2A mutations according to the number of patients affected by melanoma in a family
    Eve Maubec
    INSERM Institut National de Santé et de Recherche Médicale, Genetic Variation and Human Diseases Unit U946, Paris, France
    J Am Acad Dermatol 67:1257-64. 2012
    ..However, in families with 2 patients with CM, which represent the majority of familial melanoma, these factors have been rarely studied...
  2. doi request reprint Characteristics of the coexistence of melanoma and renal cell carcinoma
    Eve Maubec
    National Institute of Health and Medical Research, Paris, France
    Cancer 116:5716-24. 2010
    ..The objective of the current study was to analyze a series of 42 patients with both MM and RCC to identify clinical and pathologic features as well as risk factors of this association...
  3. ncbi request reprint Mixed nonseminomatous germ cell tumor presenting as a subcutaneous tissue mass
    Eve Maubec
    Institut Gustave Roussy, Villejuif, Paris, France
    Am J Dermatopathol 28:523-5. 2006
    ..They mainly consist of mature teratomas in children. Only 2 cases have been reported in adults...
  4. ncbi request reprint F-18 fluorodeoxy-D-glucose positron emission tomography scan in the initial evaluation of patients with a primary melanoma thicker than 4 mm
    Eve Maubec
    Department of Dermatology, Institut Gustave Roussy, Villejuif Cedex, France
    Melanoma Res 17:147-54. 2007
    ..Sentinel lymph node biopsy remains the technique of choice for the most accurate initial staging...
  5. doi request reprint Phase II study of cetuximab as first-line single-drug therapy in patients with unresectable squamous cell carcinoma of the skin
    Eve Maubec
    Hopital Bichat, Service de Dermatologie, 46 rue Henri Huchard, Paris, cedex 75877, France
    J Clin Oncol 29:3419-26. 2011
    ..To evaluate the efficacy and safety of cetuximab, a monoclonal antibody that inhibits the epidermal growth factor receptor (EGFR), as a first-line monotherapy in patients with unresectable squamous cell carcinoma of the skin (SCCS)...
  6. pmc Pregnancy promotes melanoma metastasis through enhanced lymphangiogenesis
    Kiarash Khosrotehrani
    Universite Pierre et Marie Curie, University Paris 06, Paris, France
    Am J Pathol 178:1870-80. 2011
    ..In conclusion, pregnancy results in increased lymphangiogenesis and subsequent metastasis. Caution should be applied in the management of patients with advanced-stage melanoma during gestation...
  7. ncbi request reprint Mature cytotoxic CD56(bright)/CD16(+) natural killer cells can infiltrate lymph nodes adjacent to metastatic melanoma
    Meriem Messaoudene
    Authors Affiliations Inserm U1016, CNRS UMR 8104, Institut Cochin APHP, Department of Dermatology, Hospital Cochin, University Paris Descartes APHP, Department of Dermatology APHP, Department of Surgery, Hospital Bichat, University Paris Diderot Surgery Department, Institut Curie, rue d Ulm Paris Hospital Foch, Suresnes Centre de Recherche des Cordeliers, 15 rue de l école de médecine and INSERM U1015 INSERM, Institut Gustave Roussy, Villejuif, Paris, France
    Cancer Res 74:81-92. 2014
    ..Taken together, the results offer evidence that adjuvant immunotherapy that targets NK cells in M-LN for activation may improve treatment of patients with sentinel lymph node-positive melanoma...
  8. doi request reprint Progressive upregulation of PD-1 in primary and metastatic melanomas associated with blunted TCR signaling in infiltrating T lymphocytes
    Maxime Chapon
    Institut Cochin, INSERM, U1016, Paris, France
    J Invest Dermatol 131:1300-7. 2011
    ....
  9. pmc Distinct merkel cell polyomavirus molecular features in tumour and non tumour specimens from patients with merkel cell carcinoma
    Hélène C Laude
    Universite Paris Descartes, EA1833, Paris, France
    PLoS Pathog 6:e1001076. 2010
    ..We conclude that MCPyV molecular features in primary MCC tumour and PBMC may help to predict the course of the disease...
  10. doi request reprint Sentinel lymph node biopsy or nodal observation in melanoma: a prospective study of patient choices
    Florent Grange
    Service de Dermatologie, Hopital Robert Debre, Reims, France
    Dermatol Surg 37:199-206. 2011
    ..There is no consensus regarding the therapeutic utility of sentinel lymph node biopsy (SLNB) versus that of nodal observation (NO) in melanoma...
  11. pmc Fetal microchimeric cells participate in tumour angiogenesis in melanomas occurring during pregnancy
    Sau Nguyen Huu
    Laboratoire de Physiopathologie du Developpement, Universite Pierre et Marie Currie University of Paris 06, EA4053, Paris, France
    Am J Pathol 174:630-7. 2009
    ..Further studies are needed to assess whether the fetal contribution to lymphangiogenesis may alter the prognosis of the maternal tumor...
  12. ncbi request reprint Immunohistochemical analysis of EGFR and HER-2 in patients with metastatic squamous cell carcinoma of the skin
    Eve Maubec
    Department of Dermatology, Hopital Bichat, Paris, France
    Anticancer Res 25:1205-10. 2005
    ..Overexpression of EGFR and of HER-2 proteins has been reported. The purpose of this study was to investigate the expression of EGFR and HER-2 in a series of metastatic SCC of the skin...
  13. ncbi request reprint Imatinib mesylate as a preoperative therapy in dermatofibrosarcoma: results of a multicenter phase II study on 25 patients
    Delphine Kerob
    AP HP Department of Dermatology, Hopital Saint Louis, Universite Paris 7 Denis Diderot, Paris, France
    Clin Cancer Res 16:3288-95. 2010
    ..The secondary aims were to determine tolerance, objective response from imaging results (ultrasound and magnetic resonance imaging), and pathologic responses observed in sequential tissue specimens...
  14. doi request reprint Clinical activity of lenalidomide in visceral human immunodeficiency virus-related Kaposi sarcoma
    Maud Steff
    Service de Dermatologie, Hopital Bichat, Assistance Publique Hopitaux de Paris, Paris, France2Université Paris Diderot Sorbonne Paris Cité, Paris, France
    JAMA Dermatol 149:1319-22. 2013
    ..This engenders interest in evaluating thalidomide analogues such as lenalidomide with better toxicity profiles. To our knowledge, we describe for the first time a patient with visceral KS successfully treated with lenalidomide...
  15. pmc Phenotypic and functional characteristics of blood natural killer cells from melanoma patients at different clinical stages
    Giulia Fregni
    Cochin Institute, Institut National de la Santé et de la Recherche Médicale INSERM U1016, Centre National de la Recherche Scientifique Unite Mixte de Recherche 8104, University Paris Descartes, Paris, France
    PLoS ONE 8:e76928. 2013
    ..Finally, we showed that NK cells infiltrated primary melanomas and displayed a predominant peritumoral distribution. These results are new arguments for the development of NK-based therapies in melanoma patients. ..
  16. ncbi request reprint Primary cutaneous diffuse large B-cell lymphoma, leg type: clinicopathologic features and prognostic analysis in 60 cases
    Florent Grange
    Department of Dermatology, Hopital Robert Debre, avenue du Général Koenig, Reims 51100, France
    Arch Dermatol 143:1144-50. 2007
    ....
  17. pmc The contribution of large genomic deletions at the CDKN2A locus to the burden of familial melanoma
    F Lesueur
    Groupe Mélanome, Institut Gustave Roussy, FRE2939 CNRS Université Paris Sud, Villejuif, France
    Br J Cancer 99:364-70. 2008
    ..1% of total mutations in this series (1 of 48), confirming that they explain a very small proportion of CMM susceptibility. In addition, we excluded a new gene on 9p21, KLHL9, as being a major CMM gene...
  18. doi request reprint Minocycline-induced DRESS: evidence for accumulation of the culprit drug
    Eve Maubec
    Department of Dermatology, Hopital Henri Mondor, Assistance Publique Hopitaux de Paris, Creteil, France
    Dermatology 216:200-4. 2008
    ..Minocycline-induced drug rash with eosinophilia and systemic symptoms (DRESS) may have a prolonged course, especially in African and African-American patients...
  19. pmc Early T cell signalling is reversibly altered in PD-1+ T lymphocytes infiltrating human tumors
    Shu Fang Wang
    INSERM, U1016, Institut Cochin, Paris, France
    PLoS ONE 6:e17621. 2011
    ..This work highlights some of the molecular modifications contributing to functional defects of human TIL...
  20. doi request reprint The mineralocorticoid receptor as a novel player in skin biology: beyond the renal horizon?
    Nicolette Farman
    INSERM U 872, Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie, Paris, France
    Exp Dermatol 19:100-7. 2010
    ..Because its activating ligand also includes glucocorticoids, that are widely used in dermatology, we propose that the MR may be also involved in the side-effects of corticoids, opening novel options for therapeutical intervention...