Frédéric Martinon

Summary

Country: France

Publications

  1. ncbi request reprint Improved protection against simian immunodeficiency virus mucosal challenge in macaques primed with a DNA vaccine and boosted with the recombinant modified vaccinia virus Ankara and recombinant Semliki Forest virus
    Frédéric Martinon
    CEA, Service d Immuno Virologie, DSV, iMETI, 18 route du Panorama, Fontenay aux Roses, France
    Vaccine 26:532-45. 2008
  2. doi request reprint Persistent immune responses induced by a human immunodeficiency virus DNA vaccine delivered in association with electroporation in the skin of nonhuman primates
    Frédéric Martinon
    Division of ImmunoVirology, Life Sciences Program DSV, Institute for Emerging Diseases and Innovative Therapies, Atomic Energy Commission CEA, Fontenay aux Roses, France
    Hum Gene Ther 20:1291-307. 2009
  3. doi request reprint Cynomolgus macaques immunized with two HIV-1 Tat stabilized proteins raise strong and long-lasting immune responses with a pattern of Th1/Th2 response differing from that in mice
    Sabrina Turbant
    CEA, DSV, iBiTec S, SPI, LIAS, Gif sur Yvette, F 91191 France
    Vaccine 27:5349-56. 2009
  4. pmc Macrophage- and Neutrophil-Derived TNF-α Instructs Skin Langerhans Cells To Prime Antiviral Immune Responses
    Olivier Epaulard
    French Alternative Energies and Atomic Energy Commission, Division of Immuno Virology, Institute for Emerging Diseases and Innovative Therapies, Infectious Diseases Models for Innovative Therapies Center, 92265 Fontenay aux Roses, France Unité Mixte de Recherche E1, Universite Paris Sud, 91405 Orsay, France Vaccine Research Institute, 94010 Creteil, France Infectious Diseases Unit, Grenoble University Hospital, 38043 Grenoble, France
    J Immunol 193:2416-26. 2014
  5. ncbi request reprint Electroporation-mediated intradermal delivery of DNA vaccines in nonhuman primates
    Lucille Adam
    Division of Immuno Virology, CEA, Institute for Emerging Diseases and Innovative Therapies iMETI, Fontenay aux Roses, France
    Methods Mol Biol 1121:309-13. 2014
  6. pmc CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates
    Gabrielle Romain
    CEA, Division of Immuno Virology, Institute for Emerging Diseases and Innovative Therapies, DSV, Fontenay aux Roses, France
    Eur J Immunol 42:2019-30. 2012

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Improved protection against simian immunodeficiency virus mucosal challenge in macaques primed with a DNA vaccine and boosted with the recombinant modified vaccinia virus Ankara and recombinant Semliki Forest virus
    Frédéric Martinon
    CEA, Service d Immuno Virologie, DSV, iMETI, 18 route du Panorama, Fontenay aux Roses, France
    Vaccine 26:532-45. 2008
    ..These results highlight the power of live attenuated virus vectors for vaccination strategies...
  2. doi request reprint Persistent immune responses induced by a human immunodeficiency virus DNA vaccine delivered in association with electroporation in the skin of nonhuman primates
    Frédéric Martinon
    Division of ImmunoVirology, Life Sciences Program DSV, Institute for Emerging Diseases and Innovative Therapies, Atomic Energy Commission CEA, Fontenay aux Roses, France
    Hum Gene Ther 20:1291-307. 2009
    ..This strategy is an attractive approach for vaccination in humans because of its high efficacy and the possible use of newly developed devices for EP...
  3. doi request reprint Cynomolgus macaques immunized with two HIV-1 Tat stabilized proteins raise strong and long-lasting immune responses with a pattern of Th1/Th2 response differing from that in mice
    Sabrina Turbant
    CEA, DSV, iBiTec S, SPI, LIAS, Gif sur Yvette, F 91191 France
    Vaccine 27:5349-56. 2009
    ....
  4. pmc Macrophage- and Neutrophil-Derived TNF-α Instructs Skin Langerhans Cells To Prime Antiviral Immune Responses
    Olivier Epaulard
    French Alternative Energies and Atomic Energy Commission, Division of Immuno Virology, Institute for Emerging Diseases and Innovative Therapies, Infectious Diseases Models for Innovative Therapies Center, 92265 Fontenay aux Roses, France Unité Mixte de Recherche E1, Universite Paris Sud, 91405 Orsay, France Vaccine Research Institute, 94010 Creteil, France Infectious Diseases Unit, Grenoble University Hospital, 38043 Grenoble, France
    J Immunol 193:2416-26. 2014
    ..Understanding the importance of local immune networks will help us to design new and effective vaccines against microbial pathogens. ..
  5. ncbi request reprint Electroporation-mediated intradermal delivery of DNA vaccines in nonhuman primates
    Lucille Adam
    Division of Immuno Virology, CEA, Institute for Emerging Diseases and Innovative Therapies iMETI, Fontenay aux Roses, France
    Methods Mol Biol 1121:309-13. 2014
    ..Here we describe a method for the EP-mediated intradermal delivery of DNA vaccines in nonhuman primates, as a model for preclinical development of human vaccines, using noninvasive needleless electrodes. ..
  6. pmc CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates
    Gabrielle Romain
    CEA, Division of Immuno Virology, Institute for Emerging Diseases and Innovative Therapies, DSV, Fontenay aux Roses, France
    Eur J Immunol 42:2019-30. 2012
    ..In high responding animals, the numbers of polyfunctional CD8(+) T cells increased with the number of booster injections. This DC-based vaccine strategy elicited immune responses relevant to the DC subsets generated in vitro...