Michel Marre

Summary

Country: France

Publications

  1. ncbi Before oral agents fail: the case for starting insulin early
    M Marre
    Service de diabétologie endocrinologie, Hopital Bichat Claude Bernard, Paris, France
    Int J Obes Relat Metab Disord 26:S25-30. 2002
  2. ncbi Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity
    Nabila Bouatia-Naji
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    BMC Med Genet 8:44. 2007
  3. ncbi The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies
    Stephane Cauchi
    CNRS UMR8090, Institut de Biologie de Lille, Génomique et Physiologie Moléculaire des Maladies Métaboliques, Lille, France
    BMC Med Genet 9:45. 2008
  4. ncbi Analysis of KLF transcription factor family gene variants in type 2 diabetes
    Ruth Gutierrez-Aguilar
    UMR8090, CNRS, Institute of Biologie Institute Pasteur de Lille, Lille, France
    BMC Med Genet 8:53. 2007
  5. ncbi Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population
    Claire Cheyssac
    CNRS UMR 8090, Institut de Biologie de Lille, Institut Pasteur, 59019 Lille, France
    BMC Med Genet 7:44. 2006
  6. ncbi Evaluating the association of common PBX1 variants with type 2 diabetes
    Konsta Duesing
    Genomic Medicine, Imperial College London, Hammersmith Campus, Du Cane Rd, London W12 0NN, UK
    BMC Med Genet 9:14. 2008
  7. ncbi Evaluating the association of common APOA2 variants with type 2 diabetes
    Konsta Duesing
    Genomic Medicine, Imperial College London, Hammersmith Campus, Du Cane Rd, London, W12 0NN, UK
    BMC Med Genet 10:13. 2009
  8. ncbi Nephropathy in type 1 diabetes
    Michel Marre
    Service d Endocrinologie Diabétologie Métabolisme Nutrition, Centre Hospitalier Universitaire Bichat Claude Bernard, Paris, France
    Semin Vasc Med 2:97-107. 2002
  9. ncbi Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study
    Michel Marre
    Hopital Bichat, Service de Diabétologie et d Endocrinologie, Paris, France
    J Hypertens 22:1613-22. 2004
  10. ncbi Nateglinide improves glycaemic control when added to metformin monotherapy: results of a randomized trial with type 2 diabetes patients
    M Marre
    Department of Diabetology, Hospital Bichat Claude Bernard, Paris, France
    Diabetes Obes Metab 4:177-86. 2002

Collaborators

Detail Information

Publications88

  1. ncbi Before oral agents fail: the case for starting insulin early
    M Marre
    Service de diabétologie endocrinologie, Hopital Bichat Claude Bernard, Paris, France
    Int J Obes Relat Metab Disord 26:S25-30. 2002
    ..In this context, the use of premixed insulin analogues in combination with OHAs allows effective postprandial glucose control, a twice-daily injection regimen and a short meal-injection interval...
  2. ncbi Secretory granule neuroendocrine protein 1 (SGNE1) genetic variation and glucose intolerance in severe childhood and adult obesity
    Nabila Bouatia-Naji
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    BMC Med Genet 8:44. 2007
    ..The aim of this study is to analyze associations of SGNE1 genetic variation with obesity and metabolism related quantitative traits...
  3. ncbi The genetic susceptibility to type 2 diabetes may be modulated by obesity status: implications for association studies
    Stephane Cauchi
    CNRS UMR8090, Institut de Biologie de Lille, Génomique et Physiologie Moléculaire des Maladies Métaboliques, Lille, France
    BMC Med Genet 9:45. 2008
    ....
  4. ncbi Analysis of KLF transcription factor family gene variants in type 2 diabetes
    Ruth Gutierrez-Aguilar
    UMR8090, CNRS, Institute of Biologie Institute Pasteur de Lille, Lille, France
    BMC Med Genet 8:53. 2007
    ..Moreover, several of these proteins have been implicated in glucose homeostasis, making them candidate genes for involvement in type 2 diabetes (T2D)...
  5. ncbi Analysis of common PTPN1 gene variants in type 2 diabetes, obesity and associated phenotypes in the French population
    Claire Cheyssac
    CNRS UMR 8090, Institut de Biologie de Lille, Institut Pasteur, 59019 Lille, France
    BMC Med Genet 7:44. 2006
    ....
  6. ncbi Evaluating the association of common PBX1 variants with type 2 diabetes
    Konsta Duesing
    Genomic Medicine, Imperial College London, Hammersmith Campus, Du Cane Rd, London W12 0NN, UK
    BMC Med Genet 9:14. 2008
    ..PBX1 is a biological candidate gene for type 2 diabetes at the 1q21-q24 susceptibility locus. The aim of this study was to evaluate the association of common PBX1 variants with type 2 diabetes in French Caucasian subjects...
  7. ncbi Evaluating the association of common APOA2 variants with type 2 diabetes
    Konsta Duesing
    Genomic Medicine, Imperial College London, Hammersmith Campus, Du Cane Rd, London, W12 0NN, UK
    BMC Med Genet 10:13. 2009
    ..The aim of this study was to examine if HapMap phase II tag SNPs in APOA2 are associated with type 2 diabetes and quantitative traits in French Caucasian subjects...
  8. ncbi Nephropathy in type 1 diabetes
    Michel Marre
    Service d Endocrinologie Diabétologie Métabolisme Nutrition, Centre Hospitalier Universitaire Bichat Claude Bernard, Paris, France
    Semin Vasc Med 2:97-107. 2002
    ..Blocking the course of nephropathy by blockers of the renin-angiotensin system relies on solid pathophysiological hypotheses and has proved to be efficacious for improving the prognosis of type 1 diabetes nephropathy...
  9. ncbi Equivalence of indapamide SR and enalapril on microalbuminuria reduction in hypertensive patients with type 2 diabetes: the NESTOR Study
    Michel Marre
    Hopital Bichat, Service de Diabétologie et d Endocrinologie, Paris, France
    J Hypertens 22:1613-22. 2004
    ....
  10. ncbi Nateglinide improves glycaemic control when added to metformin monotherapy: results of a randomized trial with type 2 diabetes patients
    M Marre
    Department of Diabetology, Hospital Bichat Claude Bernard, Paris, France
    Diabetes Obes Metab 4:177-86. 2002
    ..This study evaluated the addition of nateglinide, a d-phenylalanine derivative that restores early phase insulin release, to metformin in type 2 diabetes patients stabilized on high-dose metformin...
  11. ncbi Liraglutide, a once-daily human GLP-1 analogue, added to a sulphonylurea over 26 weeks produces greater improvements in glycaemic and weight control compared with adding rosiglitazone or placebo in subjects with Type 2 diabetes (LEAD-1 SU)
    M Marre
    Service d Endocrinologie Diabétologie Nutrition, Groupe Hospitalier Bichat Claude Bernard, Paris, France
    Diabet Med 26:268-78. 2009
    ..To compare the effects of combining liraglutide (0.6, 1.2 or 1.8 mg/day) or rosiglitazone 4 mg/day (all n >or= 228) or placebo (n = 114) with glimepiride (2-4 mg/day) on glycaemic control, body weight and safety in Type 2 diabetes...
  12. ncbi Effects of low dose ramipril on cardiovascular and renal outcomes in patients with type 2 diabetes and raised excretion of urinary albumin: randomised, double blind, placebo controlled trial (the DIABHYCAR study)
    Michel Marre
    Endocrinologie Diabétologie Nutrition, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique des Hopitaux de Paris, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    BMJ 328:495. 2004
    ..To investigate whether a low dose of the angiotensin converting enzyme (ACE) inhibitor ramipril lowers cardiovascular and renal events in patients with type 2 diabetes who have microalbuminuria or proteinuria...
  13. ncbi Effect of indapamide SR on microalbuminuria--the NESTOR study (Natrilix SR versus Enalapril Study in Type 2 diabetic hypertensives with micrOalbuminuRia)--rationale and protocol for the main trial
    M Marre
    Hopital Bichat, Paris, France
    J Hypertens Suppl 21:S19-24. 2003
    ..This study will complete the knowledge of the efficacy of indapamide SR in hypertension and target organ damage and will provide valuable information on the management of type 2 diabetic hypertensives with microalbuminuria...
  14. ncbi [Prediction, screening and treatment of renal complications of diabetes]
    M Marre
    Service de diabétologie endocrinologie nutrition Groupe hospitalier Bichat Claude Bernard 75877 Paris
    Rev Prat 51:1769-75. 2001
    ..Treatment relies up on early and liberal use of several antihypertensive agents. Among them, angiotensin I converting enzyme inhibitors rank first, because of their efficacy...
  15. ncbi Hereditary factors in the development of diabetic renal disease
    M Marre
    Diabetes Departments, Hopital Bichat, Paris, France
    Diabetes Metab 26:30-6. 2000
    ..The role of angiotensin-I-converting enzyme (ACE) insertion/deletion (I/D) polymorphism has been suspected for several years. Evidence of its possible role in the development and progression of diabetic renal disease is presented here...
  16. ncbi A KQ121 variant in the PC-1 gene and diabetic nephropathy: discrepant results between North and South Europe
    Michel Marre
    , Centre Hospitalier Universitaire BICHAT - Claude BERNARD, Paris, France
    Nephrol Dial Transplant 17:1546-7. 2002
  17. ncbi Determinants of elevated urinary albumin in the 4,937 type 2 diabetic subjects recruited for the DIABHYCAR Study in Western Europe and North Africa
    M Marre
    Service d endocrinologie, Diabetologie, Maladies Metaboliques, Hopital Bichat, Paris, France
    Diabetes Care 23:B40-8. 2000
    ..In this article, we report the characteristics of the randomized patients...
  18. ncbi [What allows a type 1 diabetic to be well controlled]
    M Marre
    Service de Diabetologie, Endocrinologie, Metabolisme, Groupe Hospitalier Bichat Claude Bernard, Paris, France
    Diabetes Metab 28:2S7-2S14. 2002
    ..Information tools (from oral information to website) and strategies (from usual educational courses by the diabetes care team to general public information) remain to be fully evaluated...
  19. ncbi Association of ADIPOQ genetic variants and plasma adiponectin isoforms with the risk of incident renal events in type 2 diabetes
    Riphed Jaziri
    INSERM, U695, Genetic Determinants for Type 2 Diabetes and Its Vascular Complications, Paris, France
    Nephrol Dial Transplant 25:2231-7. 2010
    ..We investigated the possible association of polymorphisms in the adiponectin gene and baseline adiponectin levels with the incidence of renal events in subjects with type 2 diabetes...
  20. ncbi Hyperadiponectinemia is independent of kidney function, diabetes duration, and control in type 1 diabetic patients without microangiopathy
    Charbel Abi Khalil
    Service de Diabétologie Endocrinologie Nutrition, Hopital Bichat, Assistance Publique des Hopitaux de Paris, 75877 Paris, France
    J Clin Endocrinol Metab 96:E485-7. 2011
    ..We studied whether ADPN and its specific isoforms were elevated in T1D without microangiopathy and whether they were related to kidney function...
  21. ncbi Allelic variations in superoxide dismutase-1 (SOD1) gene are associated with increased risk of diabetic nephropathy in type 1 diabetic subjects
    Kamel Mohammedi
    INSERM, Research Unit 695, Paris, France
    Mol Genet Metab 104:654-60. 2011
    ..We investigated associations of allelic variations in SOD1 gene with nephropathy in patients with type 1 diabetes...
  22. ncbi G/T substitution in intron 1 of the UNC13B gene is associated with increased risk of nephropathy in patients with type 1 diabetes
    David Alexandre Tregouet
    INSERM, Paris, France, and Pierre and Marie Curie Paris VI University, Paris, France
    Diabetes 57:2843-50. 2008
    ..The objective of the European Rational Approach for the Genetics of Diabetic Complications (EURAGEDIC) study is to identify nephropathy susceptibility genes. We report molecular genetic studies for 127 candidate genes for nephropathy...
  23. ncbi Associations of the -344 T>C and the 3097 G>A polymorphisms of CYP11B2 gene with hypertension, type 2 diabetes, and metabolic syndrome in a French population
    Naïma Muñoz Bellili
    Institut National de la Santé et de la Recherche Médicale INSERM U695, Déterminants Génétiques du Diabète de Type 2 et de ses Complications Cardiovasculaires, Faculte Xavier Bichat, Universite Denis Diderot Paris 7, Paris, France
    Am J Hypertens 23:660-7. 2010
    ..We assessed the association of two polymorphisms -344 T>C and the 3097 G>A in the aldosterone synthase gene (CYP11B2) with prevalent and incident hypertension (HT), type 2 diabetes (T2D), and the metabolic syndrome (MetS)...
  24. ncbi Allelic variations in superoxide dismutase-1 (SOD1) gene and renal and cardiovascular morbidity and mortality in type 2 diabetic subjects
    Ana Luísa Neves
    INSERM, Research Unit 695, Paris, France
    Mol Genet Metab 106:359-65. 2012
    ..We investigated associations of allelic variations in SOD1 gene with nephropathy and cardiovascular complications in patients with type 2 diabetes...
  25. ncbi Low water intake and risk for new-onset hyperglycemia
    Ronan Roussel
    Universite Paris Diderot, Paris 7, Paris, France
    Diabetes Care 34:2551-4. 2011
    ..Water intake alters vasopressin secretion. Recent findings reveal an independent association between plasma copeptin, a surrogate for vasopressin, and risk of diabetes...
  26. ncbi Association of common variants in NPPA and NPPB with blood pressure does not translate into kidney damage in a general population study
    Suliya Maimaitiming
    INSERM, U695, Paris, France
    J Hypertens 28:1230-3. 2010
    ....
  27. ncbi Dairy consumption and the incidence of hyperglycemia and the metabolic syndrome: results from a french prospective study, Data from the Epidemiological Study on the Insulin Resistance Syndrome (DESIR)
    Frederic Fumeron
    1INSERM U695, Paris, France
    Diabetes Care 34:813-7. 2011
    ..We assess the influence of dairy products on 9-year incident MetS and on impaired fasting glycemia and/or type 2 diabetes (IFG/T2D)...
  28. ncbi Cause-specific mortality in diabetes: recent changes in trend mortality
    Charbel Abi Khalil
    Diabetology, Endocrinology and Nutrition Department, Hopital Bichat Claude Bernard, Paris, France
    Eur J Prev Cardiol 19:374-81. 2012
    ..This counteracts the diminution of diabetes-related mortality that would move forward on an ascending slope in the next decades...
  29. ncbi The common -866G>A variant in the promoter of UCP2 is associated with decreased risk of coronary artery disease in type 2 diabetic men
    Nadir Cheurfa
    Institut National de la Sante et de la Recherche Medicale, Research Unit 695, Paris, France
    Diabetes 57:1063-8. 2008
    ..We investigated association of this variant with coronary artery disease (CAD) in two cohorts of type 2 diabetic subjects...
  30. ncbi The CETP TaqIB polymorphism is associated with the risk of sudden death in type 2 diabetic patients
    Isabelle Porchay-Baldérelli
    Institut National de la Sante et de la Recherche Medicale, U695, Genetic Determinants for Type 2 Diabetes and Its Vascular Complications, Paris, France
    Diabetes Care 30:2863-7. 2007
    ..We investigated the association of the CETP TaqIB polymorphism with CHD, and sudden death in particular, in a prospective cohort of type 2 diabetic patients...
  31. ncbi Improved glycaemic control with metformin-glibenclamide combined tablet therapy (Glucovance) in Type 2 diabetic patients inadequately controlled on metformin
    Michel Marre
    Diabetology-Endocrinology-Metabolism Unit, Hospital of Xavier Bichat, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Diabet Med 19:673-80. 2002
    ....
  32. ncbi Fetal exposure to maternal type 1 diabetes is associated with renal dysfunction at adult age
    Charbel Abi Khalil
    Diabetes Department, Groupe Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Diabetes 59:2631-6. 2010
    ..We tested whether this observation translates into renal dysfunction in humans by studying renal functional reserve in adult offspring exposed in utero to maternal type 1 diabetes...
  33. ncbi ABCA1 single nucleotide polymorphisms on high-density lipoprotein-cholesterol and overweight: the D.E.S.I.R. study
    Isabelle Porchay
    Institut National de la Sante et de la Recherche Medicale, Unité 695, Xavier Bichat School of Medicine, Paris, France
    Obesity (Silver Spring) 14:1874-9. 2006
    ..This study suggests that ABCA1 gene polymorphisms modulate HDL-C concentrations, in interaction with BMI, and, thus, they might influence cardiovascular risk in the general population...
  34. ncbi Association between angiotensin-converting enzyme gene polymorphisms and diabetic nephropathy: case-control, haplotype, and family-based study in three European populations
    Samy Hadjadj
    CHU de Poitiers, Department of Diabetology, Poitiers University Hospital, Poitiers, France
    J Am Soc Nephrol 18:1284-91. 2007
    ..This study population is suitable to search for additional candidate genes for DN...
  35. ncbi Investigation of the human ANP gene in type 1 diabetic nephropathy: case-control and follow-up studies
    Ronan Roussel
    Diabetologie, Hopital Bichat, Assistance Publique Hopitaux de Paris, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Diabetes 53:1394-8. 2004
    ..93, 95% CI 1.15-3.24; P = 0.012) was further confirmed by the haplotype analysis, suggesting that the 2238C allele of PND may affect the course of nephropathy in inadequately controlled type 1 diabetic patients...
  36. ncbi Reducing cardiovascular risk in diabetes
    Michel Marre
    Groupe Hospitalier Bichat Claude Bernard, , Paris, France
    J Hypertens Suppl 25:S19-22. 2007
    ..This new understanding of the pathophysiology of cardiovascular disease in patients with diabetes may help in addressing the underlying processes at an earlier stage of disease...
  37. ncbi Kallikrein protects against microalbuminuria in experimental type I diabetes
    Sophie Bodin
    INSERM UMR 872, Centre de Recherche des Cordeliers, Paris, France
    Kidney Int 76:395-403. 2009
    ....
  38. ncbi Polymorphisms of the lamina maturation pathway and their association with the metabolic syndrome: the DESIR prospective study
    Bénédicte Fontaine-Bisson
    INSERM, UMR_S 937, 75013, Paris, France
    J Mol Med (Berl) 88:193-201. 2010
    ..No robust interaction between SNPs located in different genes on the risk of MS was identified. In conclusion, we did not observe any convincing evidence that common polymorphisms of the lamina pathway could modulate the risk of MS...
  39. ncbi Metformin use and mortality among patients with diabetes and atherothrombosis
    Ronan Roussel
    INSERM, Department of Diabetology, Bichat Hospital, Paris, France
    Arch Intern Med 170:1892-9. 2010
    ..However, metformin is often not considered in patients with cardiovascular conditions because of concerns about its safety...
  40. ncbi Hemoglobin A1c and fasting plasma glucose levels as predictors of retinopathy at 10 years: the French DESIR study
    Pascale Massin
    Ophthalmology Department, Assistance Publique Hopitaux de Paris, Hopital Lariboisiere, Paris, France
    Arch Ophthalmol 129:188-95. 2011
    ..To evaluate the predictive values of hemoglobin A(1c) (HbA(1c)) and fasting plasma glucose (FPG) for retinopathy 10 years after the baseline examination...
  41. ncbi Effects of perindopril in hypertensive patients with or without type 2 diabetes mellitus, and with altered insulin sensitivity
    Michel Marre
    Service d Endocrinologie Diabétologie Nutrition, Groupe Hospitalier Bichat Claude Bernard, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Diab Vasc Dis Res 4:163-73. 2007
    ....
  42. ncbi Benefits of Ophdiat, a telemedical network to screen for diabetic retinopathy: a retrospective study in five reference hospital centres
    A Chabouis
    Assistance Publique Hopitaux de Paris, Paris, France
    Diabetes Metab 35:228-32. 2009
    ..The aim of this study was to evaluate the benefits of this programme in a hospital setting...
  43. ncbi Transforming growth factor-beta 1 production is correlated with genetically determined ACE expression in congenic rats: a possible link between ACE genotype and diabetic nephropathy
    Maria E Pueyo
    INSERM U460, and Service de Diabetologie, CHU Bichat, Paris, France
    Diabetes 53:1111-8. 2004
    ..These results show that TGF-beta 1 expression is correlated with ACE expression and suggest that this growth factor could be a link between ACE gene polymorphism and diabetic vascular complications...
  44. ncbi Type B insulin resistance syndrome associated with an immune reconstitution inflammatory syndrome in an HIV-infected woman
    Kamel Mohammedi
    Groupe Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Service d endocrinologie, Diabetologie, et Nutrition, 46 rue Henri Huchard, 75877 Paris, France
    J Clin Endocrinol Metab 96:E653-7. 2011
    ..Type B insulin resistance syndrome is a rare condition characterized by the presence of autoantibodies directed against the insulin receptor. It has been reported in association with autoimmune diseases such as systemic lupus erythematosus...
  45. ncbi Screening for diabetic retinopathy: the first telemedical approach in a primary care setting in France
    P Massin
    Departement d Ophtalmologie, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, Paris, France
    Diabetes Metab 30:451-7. 2004
    ..Fundus photography is a sensitive alternative to ophthalmoscopy for DR screening. The aim of our study was to report the first telemedical approach to this screening in a primary care setting in France...
  46. ncbi [Insulin sensitivity, blood pressure and cardiovascular diseases]
    M Marre
    Diabetologie, Endocrinologie, Metabolisme, Groupe Hospitalier Bichat, Claude Bernard, Paris, France
    Diabetes Metab 27:229-32. 2001
    ..In this study, this relationship is explored through the data of currently available clinical trials...
  47. ncbi Angiotensin-I-converting enzyme insertion/deletion polymorphism and high urinary albumin concentration in French Type 2 diabetes patients
    S Hadjadj
    Service de Medecine Interne, Endocrinologie, University Hospital, Poitiers, France
    Diabet Med 20:677-82. 2003
    ..We assessed the association between high urinary albumin concentration and ACE insertion/deletion (I/D) polymorphism, in French Type 2 diabetes patients...
  48. ncbi [IV. Management of diabetic neuropathy]
    M Marre
    Service d'Endocrinologie, , 46 rue Henri Huchard, 75018 Paris
    J Mal Vasc 27:274-5. 2002
  49. ncbi Evaluation of a new non-mydriatic digital camera for detection of diabetic retinopathy
    P Massin
    Department of Ophthalmology, Hopital Lariboisiere, Assistance Publique Hopitaux de Paris, France
    Diabet Med 20:635-41. 2003
    ....
  50. ncbi Vasopressin increases urinary albumin excretion in rats and humans: involvement of V2 receptors and the renin-angiotensin system
    Pascale Bardoux
    , , Paris, France
    Nephrol Dial Transplant 18:497-506. 2003
    ..These results bring additional support for an involvement of vasopressin in the albuminuria observed in pathological states such as diabetes mellitus or hypertension...
  51. ncbi [Prevention of cardiovascular risk in diabetes]
    Michel Marre
    Service d Endocrinologie Diabétologie Nutrition, Groupe Hospitalier Bichat Claude Bernard, Paris
    Rev Prat 57:1423-30. 2007
    ..A multiple intervention strategy was shown to be effective in type 2 diabetic subjects with microalbuminuria. Clinical trials aimed at normalizing blood glucose to reduce CV events will be available within 5 years...
  52. ncbi Prognostic value of angiotensin-I converting enzyme I/D polymorphism for nephropathy in type 1 diabetes mellitus: a prospective study
    S Hadjadj
    Medecine B, Centre Hospitalier Universitaire, Angers, Paris, France
    J Am Soc Nephrol 12:541-9. 2001
    ..The AGT M235T polymorphism was not associated with renal events. The D allele of the ACE I/D polymorphism is an independent risk factor for both the onset and the progression of diabetic nephropathy in type 1 diabetes mellitus patients...
  53. ncbi Hyperglycemia-induced defects in angiogenesis in the chicken chorioallantoic membrane model
    Etienne Larger
    INSERM U36, Chaire de Médecine Expérimentale, College de France, Paris, France
    Diabetes 53:752-61. 2004
    ..Hyperglycemia can therefore impair angiogenesis without altering the expression level of vascular growth factors through induction of apoptosis and decreased proliferation of endothelial cells...
  54. ncbi Adiponectin gene polymorphisms and adiponectin levels are independently associated with the development of hyperglycemia during a 3-year period: the epidemiologic data on the insulin resistance syndrome prospective study
    Frederic Fumeron
    EA 3516, Interactions Gènes Environnement dans les Pathologies Métaboliques à Risque Cardiovasculaire, Faculte Xavier Bichat, Paris, France
    Diabetes 53:1150-7. 2004
    ..Adiponectin gene SNPs may have several phenotypic effects that co-occur with the development of the metabolic syndrome...
  55. ncbi Reducing cardiovascular risk in diabetes
    Michel Marre
    Groupe Hospitalier Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    J Hypertens Suppl 25:S19-22. 2007
    ..This new understanding of the pathophysiology of cardiovascular disease in patients with diabetes may help in addressing the underlying processes at an earlier stage of disease...
  56. ncbi Normal and abnormal day-to-day variability of urinary albumin excretion in control and diabetic subjects
    N P Chau
    Equipe Biostat Biomath, INSERM U444, université Paris VII Denis Diderot, Paris, France
    Diabetes Metab 26:36-41. 2000
    ..It is remarkable that the day-to-day variability of UAE collapses when UAE crosses the level which has been used to define microalbuminuria...
  57. ncbi [Can coronary risks be further reduced?]
    A Tedgu
    INSERM U541, Hopital Lariboisiere, Paris, France
    Presse Med 33:1138-40. 2004
  58. ncbi GLP-1 receptor agonists today
    Michel Marre
    Department of Endocrinology, Diabetology and Nutrition, Bichat Hospital, Assistance Publique des Hopitaux de Paris, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
    Diabetes Res Clin Pract 93:317-27. 2011
    ..It also concentrates on the physiological basis for early use of GLP-1 receptor agonists, their use as an alternative to insulin therapy, the rationale for combining them with insulin and their cost-effectiveness...
  59. ncbi Analysis of 14 candidate genes for diabetic nephropathy on chromosome 3q in European populations: strongest evidence for association with a variant in the promoter region of the adiponectin gene
    Nathalie Vionnet
    INSERM U525, Centre National de Genotypage, 2, rue Gaston Crémieux, 91006 Evry Cedex, France
    Diabetes 55:3166-74. 2006
    ..50 [0.27-0.92], P = 0.026). The overall significance for this variant (nominal P = 0.011) suggests that ADIPOQ might be involved in the development of diabetic nephropathy...
  60. ncbi Efficacy of indapamide SR compared with enalapril in elderly hypertensive patients with type 2 diabetes
    Juan Garcia Puig
    Servicio de Medicina Interna, Hospital La Paz, Paseo de la Castellana 261, 28046 Madrid, Spain
    Am J Hypertens 20:90-7. 2007
    ....
  61. ncbi Assessment of patients' and physicians' compliance to an ACE inhibitor treatment based on urinary N-acetyl Ser-Asp-Lys-Pro determination in the Noninsulin-Dependent Diabetes, Hypertension, Microalbuminuria, Proteinuria, Cardiovascular Events, and Ramipril
    Michel Azizi
    Centre d Investigations Cliniques, Hopital Europeen Georges Pompidou, 20 40 rue Leblanc, 75908 Paris Cedex 15, France
    Diabetes Care 29:1331-6. 2006
    ..25 mg o.d.) with placebo in 4,912 patients with type 2 diabetes and microalbuminuria/proteinuria...
  62. ncbi Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-Protect 2): a randomised placebo-controlled trial
    Anne Katrin Sjølie
    Department of Ophthalmology, Odense University Hospital, Odense, Denmark
    Lancet 372:1385-93. 2008
    ..Diabetic retinopathy remains a leading cause of visual loss in people of working age. We examined whether candesartan treatment could slow the progression and, secondly, induce regression of retinopathy in people with type 2 diabetes...
  63. ncbi Effect of candesartan on prevention (DIRECT-Prevent 1) and progression (DIRECT-Protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials
    Nish Chaturvedi
    International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College Healthcare NHS Trust, London, UK
    Lancet 372:1394-402. 2008
    ..We therefore designed the DIabetic REtinopathy Candesartan Trials (DIRECT) Programme to assess whether candesartan could reduce the incidence and progression of retinopathy in type 1 diabetes...
  64. ncbi The common P446L polymorphism in GCKR inversely modulates fasting glucose and triglyceride levels and reduces type 2 diabetes risk in the DESIR prospective general French population
    Martine Vaxillaire
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    Diabetes 57:2253-7. 2008
    ..We evaluated, in a general French population, the contribution of the GCKR rs1260326-P446L polymorphism to quantitative metabolic parameters and to dyslipidemia and hyperglycemia risk...
  65. ncbi Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes
    Anushka Patel
    N Engl J Med 358:2560-72. 2008
    ..5% yielded a 10% relative reduction in the combined outcome of major macrovascular and microvascular events, primarily as a consequence of a 21% relative reduction in nephropathy. (ClinicalTrials.gov number, NCT00145925.)..
  66. ncbi Prognostic value of the insertion/deletion polymorphism of the ACE gene in type 2 diabetic subjects: results from the Non-insulin-dependent Diabetes, Hypertension, Microalbuminuria or Proteinuria, Cardiovascular Events, and Ramipril (DIABHYCAR), Diabete d
    Samy Hadjadj
    Centre Hospitalier Universitaire Poitiers, Endocrinology, Diabetology, Poitiers, France
    Diabetes Care 31:1847-52. 2008
    ..We tested whether determination of the ACE insertion/deletion polymorphism is useful for renal and cardiovascular prognoses of type 2 diabetic subjects...
  67. ncbi Modulation of the renal response to ACE inhibition by ACE insertion/deletion polymorphism during hyperglycemia in normotensive, normoalbuminuric type 1 diabetic patients
    Laurent Weekers
    Department of Medicine, Centre Hospitalier Universitaire du Sart Tilman, Liege, Belgium
    Diabetes 54:2961-7. 2005
    ..018; MAP, 0.018; and total renal resistances, 0.055). These results provide a basis to different renal responses to ACE inhibition according to ACE genotype in type 1 diabetes...
  68. ncbi A polymorphism within the G6PC2 gene is associated with fasting plasma glucose levels
    Nabila Bouatia-Naji
    CNRS UMR 8090 Institute of Biology, Pasteur Institute of Lille and Lille 2 Droit et Santé University, 59019 Lille, France
    Science 320:1085-8. 2008
    ..We speculate that G6PC2 regulates FPG by modulating the set point for glucose-stimulated insulin secretion in pancreatic beta cells...
  69. ncbi Different patterns of insulin resistance in relatives of type 1 diabetic patients with retinopathy or nephropathy: the Genesis France-Belgium Study
    Samy Hadjadj
    Department of Endocrinology and Diabetology, University Hospital, Poitiers, France
    Diabetes Care 27:2661-8. 2004
    ..CONCLUSIONS: Familial insulin resistance segregates with diabetic complications: lipid disorders and obesity segregate with diabetic nephropathy, whereas arterial hypertension and obesity segregate with diabetic retinopathy...
  70. ncbi Implications of diabetes in patients with acute coronary syndromes. The Global Registry of Acute Coronary Events
    Kristen Franklin
    Department of Medicine, Division of Cardiovascular Medicine, University of Massachusetts Medical School, Worcester 01655, USA
    Arch Intern Med 164:1457-63. 2004
    ..There are limited data describing the presenting characteristics, management, and outcomes of diabetic and nondiabetic patients with an acute coronary syndrome (ACS)...
  71. ncbi TCF7L2 variation predicts hyperglycemia incidence in a French general population: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study
    Stephane Cauchi
    Imperial College, Section of Genomic Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, W12 0NN, UK
    Diabetes 55:3189-92. 2006
    ..We conclude that the TCF7L2 T at-risk allele variation (rs7903146) predicts hyperglycemia incidence in a general French population, possibly through a deleterious effect on insulin secretion...
  72. ncbi Ferritin and transferrin are both predictive of the onset of hyperglycemia in men and women over 3 years: the data from an epidemiological study on the Insulin Resistance Syndrome (DESIR) study
    Frederic Fumeron
    INSERM U695, Xavier Bichat Medical School, BP 416, 16 rue Henri Huchard, 75870 Paris Cedex 18, France
    Diabetes Care 29:2090-4. 2006
    ....
  73. ncbi Waist circumference and the metabolic syndrome predict the development of elevated albuminuria in non-diabetic subjects: the DESIR Study
    Fabrice Bonnet
    Department of Diabetology Endocrinology, CRNH, Hospital Edouard Herriot, INSERM U 449, Lyon, France
    J Hypertens 24:1157-63. 2006
    ..We investigated in both sexes whether an elevated waist circumference (WC) or the presence of the metabolic syndrome (MetS) predict the development of elevated albuminuria at 6 years...
  74. ncbi Comment on "A common genetic variant is associated with adult and childhood obesity"
    Christian Dina
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    Science 315:187; author reply 187. 2007
    ..We attempted to replicate this result in 10,265 Caucasian individuals, combining family-based, case-control, and general population studies, but found no support for a major role of this variant in obesity...
  75. ncbi NMR-based prediction of cardiovascular risk in diabetes
    Ronan Roussel
    Nat Med 13:399-400. 2007
  76. ncbi Ferritin and transferrin are associated with metabolic syndrome abnormalities and their change over time in a general population: Data from an Epidemiological Study on the Insulin Resistance Syndrome (DESIR)
    Istvan S Vari
    Institut National de la Sante et de la Recherche Medicale, unité 780 IFR69, Epidemiological and Biostatistical Research, Villejuif, France
    Diabetes Care 30:1795-801. 2007
    ..The aim of this work was to study cross-sectional and longitudinal relations between iron stocks (ferritin) and the iron transport protein (transferrin) with the metabolic syndrome and its abnormalities...
  77. ncbi Analysis of novel risk loci for type 2 diabetes in a general French population: the D.E.S.I.R. study
    Stephane Cauchi
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    J Mol Med (Berl) 86:341-8. 2008
    ..E.S.I.R. prospective cohort. However, in contrast to TCF7L2, the contribution of novel loci to T2D incidence seems only modest in the general middle-aged French population and should be replicated in larger cohorts...
  78. ncbi Does PERISCOPE provide a new perspective on diabetic treatment?
    Philippe Gabriel Steg
    JAMA 299:1603-4. 2008
  79. ncbi Evaluation of the association of IGF2BP2 variants with type 2 diabetes in French Caucasians
    Konsta Duesing
    Section of Genomic Medicine, Imperial College London, Hammersmith Campus, London, U K
    Diabetes 57:1992-6. 2008
    ....
  80. ncbi Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value
    Stephane Cauchi
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    PLoS ONE 3:e2031. 2008
    ..Our aims were to validate these markers in other European and non-European populations, then to assess their combined effect in a large French study comparing T2D and normal glucose tolerant (NGT) individuals...
  81. ncbi Retinal vascular lesions in patients of Caucasian and Asian origin with type 2 diabetes: baseline results from the ADVANCE Retinal Measurements (AdRem) study
    Ronald P Stolk
    Department of Epidemiology, University Medical Center Groningen, P O Box 30 001, 9700RB Groningen, The Netherlands
    Diabetes Care 31:708-13. 2008
    ....
  82. ncbi [Diabetes complications. Strict blood glucose controls and beyond]
    Michel Marre
    , groupe hospitalier Bichat-Claude-Bernard, Paris
    Rev Prat 57:1409-10. 2007
  83. ncbi Urinary albumin excretion is a risk factor for diabetes mellitus in men, independently of initial metabolic profile and development of insulin resistance. The DESIR Study
    Jean Michel Halimi
    Francois Rabelais University, CHRU Tours, Service de néphrologie immunologie clinique, Tours, France
    J Hypertens 26:2198-206. 2008
    ..Whether UAE predicts the development of diabetes mellitus, independently of the presence or the development of the metabolic syndrome, is unclear, in particular, in women...
  84. ncbi Impact of common type 2 diabetes risk polymorphisms in the DESIR prospective study
    Martine Vaxillaire
    UMR8090 and Institute of Biology, Lille 2 University, CNRS and Pasteur Institute, Lille, France
    Diabetes 57:244-54. 2008
    ..However, the relevance of these genes for disease prediction has not been extensively tested...
  85. ncbi European rational approach for the genetics of diabetic complications--EURAGEDIC: patient populations and strategy
    Lise Tarnow
    Steno Diabetes Center, Copenhagen, Denmark
    Nephrol Dial Transplant 23:161-8. 2008
    ..The main objective of the EURAGEDIC study was to address these problems...
  86. ncbi Effects of TCF7L2 polymorphisms on obesity in European populations
    Stephane Cauchi
    Centre National de la Recherche Scientifique 8090, Institute of Biology, Pasteur Institute, Lille, France
    Obesity (Silver Spring) 16:476-82. 2008
    ..Furthermore, our data suggest that the rs7903146 T allele may be possibly functional and associated with a nominal decrease in TCF7L2 expression in adipose tissue of individuals under calorie restriction...
  87. ncbi Variation in FTO contributes to childhood obesity and severe adult obesity
    Christian Dina
    CNRS 8090 Institute of Biology, Pasteur Institute, Lille, France
    Nat Genet 39:724-6. 2007
    ..The at-risk haplotype yields a proportion of attributable risk of 22% for common obesity. We conclude that FTO contributes to human obesity and hence may be a target for subsequent functional analyses...
  88. ncbi [New trails in diabetology]
    Michel Marre
    Med Sci (Paris) 19:771-2. 2003