Genomes and Genes
- [Intracellular signaling pathways, apoptosis and neurodegenerative diseases]Anne Marcilhac
Laboratoire EPHE de motilité cellulaire, UMR5539, Université des sciences, Montpellier II
Psychol Neuropsychiatr Vieil 2:203-14. 2004..This article reviews our understanding of intracellular signaling pathways which lead to apoptosis in the nervous system, concentrating on its possible roles in chronic neurodegenerative disorders...
- Detection and localization of calpain 3-like protease in a neuronal cell line: possible regulation of apoptotic cell death through degradation of nuclear IkappaBalphaA Marcilhac
EPHE UMR 5539, University of Montpellier II, cc107, Place Eugene Bataillon, 34000 Montpellier, France
Int J Biochem Cell Biol 38:2128-40. 2006..These data suggest a new mechanism by which calpain 3 activation is able to regulate the IkappaBalpha/NF-kappaB pathway and thus neurodegenerative processes...
- Calpain 1-gamma filamin interaction in muscle cells: a possible in situ regulation by PKC-alphaFabrice Raynaud
UMR5539, EPHE CNRS UM2, cc107, Universite Montpellier II, Place E Bataillon, 34095 Montpellier Cedex 5, France
Int J Biochem Cell Biol 38:404-13. 2006..Stimulation of PKC activity in myotubes, prevented gamma-filamin proteolysis by calpain and resulted in an increase in myotube adhesion...
- Regenerating islet-derived 1α (Reg-1α) protein is new neuronal secreted factor that stimulates neurite outgrowth via exostosin Tumor-like 3 (EXTL3) receptorIsabelle Acquatella-Tran Van Ba
University Montpellier 2, F 34095 Montpellier, France, INSERM, U710, F 34095 Montpellier, France
J Biol Chem 287:4726-39. 2012..Our findings indicate that Reg-1α regulates neurite outgrowth and suggest that this effect is mediated by its receptor EXTL3...
- Calpain 2 expression pattern and sub-cellular localization during mouse embryogenesisFabrice Raynaud
Laboratory Cellular Motility EPHE CNRS UMR 5539, University Montpellier, Montpellier, France
Int J Dev Biol 52:383-8. 2008..Thus, these data indicate that CAPN2 may represent a key factor in development from the first cell division...