Jean Michel Mansuy

Summary

Country: France

Publications

  1. doi request reprint Performance of a rapid molecular multiplex assay for the detection of influenza and picornaviruses
    Jean Michel Mansuy
    CHU de Toulouse, Hopital Purpan, Laboratoire de Virologie, Toulouse, France
    Scand J Infect Dis 44:963-8. 2012
  2. ncbi request reprint High prevalence of anti-hepatitis E virus antibodies in blood donors from South West France
    Jean Michel Mansuy
    Virology Laboratory, Purpan University Hospital, Toulouse Cedex 9, France
    J Med Virol 80:289-93. 2008
  3. pmc Immunologically silent autochthonous acute hepatitis E virus infection in France
    Jean Michel Mansuy
    Virology Laboratory, Purpan University Hospital, 31059 Toulouse, France
    J Clin Microbiol 42:912-3. 2004
  4. ncbi request reprint Hepatitis E in the south west of France in individuals who have never visited an endemic area
    Jean Michel Mansuy
    Virology Laboratory, Purpan University Hospital, Place du Dr Baylac TSA 40031, 31059, Toulouse, France
    J Med Virol 74:419-24. 2004
  5. doi request reprint Three-month pegylated interferon-alpha-2a therapy for chronic hepatitis E virus infection in a haemodialysis patient
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, Toulouse Cedex 9, France
    Nephrol Dial Transplant 25:2792-5. 2010
  6. ncbi request reprint Liver histology in patients with sporadic acute hepatitis E: a study of 11 patients from South-West France
    Jean Marie Peron
    Service d Hepato gastro enterologie, CHU Purpan and INSERM U 531, Universite Paul Sabatier, Toulouse, 31400, France
    Virchows Arch 450:405-10. 2007
  7. pmc Hepatitis E virus antibodies in blood donors, France
    Jean Michel Mansuy
    Hopital Purpan, Toulouse, France
    Emerg Infect Dis 17:2309-12. 2011
  8. doi request reprint [Hepatitis E virus: A new entity]
    Janick Selves
    CHU Purpan, Toulouse, France
    Ann Pathol 30:432-8. 2010
  9. pmc Hepatitis E virus infection without reactivation in solid-organ transplant recipients, France
    Florence Legrand-Abravanel
    Institut National de la Sante et de la Recherche Medicale, Toulouse, France
    Emerg Infect Dis 17:30-7. 2011
  10. pmc Good performance of immunoglobulin M assays in diagnosing genotype 3 hepatitis E virus infections
    Florence Legrand-Abravanel
    Laboratoire de Virologie, Institut Fédératif de Biologie, TSA 40031, CHU Toulouse Purpan, Toulouse Cedex, France
    Clin Vaccine Immunol 16:772-4. 2009

Collaborators

Detail Information

Publications24

  1. doi request reprint Performance of a rapid molecular multiplex assay for the detection of influenza and picornaviruses
    Jean Michel Mansuy
    CHU de Toulouse, Hopital Purpan, Laboratoire de Virologie, Toulouse, France
    Scand J Infect Dis 44:963-8. 2012
    ..This study evaluated the performance of the Luminex xTAG Respiratory Viral Panel (RVP) Fast assay with reference to 2 real-time PCR assays for detecting type A influenza H1 viruses and human enteroviruses and rhinoviruses...
  2. ncbi request reprint High prevalence of anti-hepatitis E virus antibodies in blood donors from South West France
    Jean Michel Mansuy
    Virology Laboratory, Purpan University Hospital, Toulouse Cedex 9, France
    J Med Virol 80:289-93. 2008
    ..As the risk factors for HEV infection in industrialized countries are still unknown, further studies are needed to clarify the epidemiology of HEV infection in the Midi-Pyrénées region...
  3. pmc Immunologically silent autochthonous acute hepatitis E virus infection in France
    Jean Michel Mansuy
    Virology Laboratory, Purpan University Hospital, 31059 Toulouse, France
    J Clin Microbiol 42:912-3. 2004
    ..We report on an autochthonous case in southwestern France in which the diagnosis was based on molecular tools rather than serological testing...
  4. ncbi request reprint Hepatitis E in the south west of France in individuals who have never visited an endemic area
    Jean Michel Mansuy
    Virology Laboratory, Purpan University Hospital, Place du Dr Baylac TSA 40031, 31059, Toulouse, France
    J Med Virol 74:419-24. 2004
    ....
  5. doi request reprint Three-month pegylated interferon-alpha-2a therapy for chronic hepatitis E virus infection in a haemodialysis patient
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, Toulouse Cedex 9, France
    Nephrol Dial Transplant 25:2792-5. 2010
    ....
  6. ncbi request reprint Liver histology in patients with sporadic acute hepatitis E: a study of 11 patients from South-West France
    Jean Marie Peron
    Service d Hepato gastro enterologie, CHU Purpan and INSERM U 531, Universite Paul Sabatier, Toulouse, 31400, France
    Virchows Arch 450:405-10. 2007
    ..Characteristic pathological signs of acute hepatitis E were severe intralobular necrosis, polymorph inflammation, and acute cholangitis with numerous neutrophils...
  7. pmc Hepatitis E virus antibodies in blood donors, France
    Jean Michel Mansuy
    Hopital Purpan, Toulouse, France
    Emerg Infect Dis 17:2309-12. 2011
    ..5% of voluntary blood donors in southwestern France. This finding suggests HEV is highly endemic to this region. The high HEV prevalence may reflect local dietary practices, such as eating uncooked pork and game products...
  8. doi request reprint [Hepatitis E virus: A new entity]
    Janick Selves
    CHU Purpan, Toulouse, France
    Ann Pathol 30:432-8. 2010
    ..Histologic lesions of chronic hepatitis E are similar to those observed in patients chronically infected with hepatitis C virus with dense lymphocytic portal infiltrate, constant peacemeal necrosis and fibrosis...
  9. pmc Hepatitis E virus infection without reactivation in solid-organ transplant recipients, France
    Florence Legrand-Abravanel
    Institut National de la Sante et de la Recherche Medicale, Toulouse, France
    Emerg Infect Dis 17:30-7. 2011
    ..Effective prophylactic measures that include those for potential zoonotic infections should reduce the risk for HEV transmission in this population...
  10. pmc Good performance of immunoglobulin M assays in diagnosing genotype 3 hepatitis E virus infections
    Florence Legrand-Abravanel
    Laboratoire de Virologie, Institut Fédératif de Biologie, TSA 40031, CHU Toulouse Purpan, Toulouse Cedex, France
    Clin Vaccine Immunol 16:772-4. 2009
    ..0, and the Assure HEV IgM rapid test (MP Diagnostics), for the routine detection of acute genotype 3 HEV. Their sensitivities were fairly good (90%, 88%, and 82%), and their specificities were excellent (100%, 99.5%, and 100%)...
  11. pmc Hepatitis E virus genotype 3 diversity, France
    Florence Legrand-Abravanel
    Institut National de la Sante et de la Recherche Medicale, Toulouse, France
    Emerg Infect Dis 15:110-4. 2009
    ..These strains are closely related to swine strains in Europe, which suggests zoonotic transmission of HEV in France...
  12. ncbi request reprint Hepatitis E is an autochthonous disease in industrialized countries. Analysis of 23 patients in South-West France over a 13-month period and comparison with hepatitis A
    Jean Marie Peron
    Service d Hepato gastro enterologie, Fédération Digestive Fédération Digestive, CHU Toulouse, Hopital Purpan, Toulouse
    Gastroenterol Clin Biol 30:757-62. 2006
    ..The aim of this study was to describe patients with acute hepatitis E in South West France and compare them with patients with acute hepatitis A...
  13. doi request reprint Pegylated interferon-alpha for treating chronic hepatitis E virus infection after liver transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, Centre Hospitalier Universitaire, Toulouse, France
    Clin Infect Dis 50:e30-3. 2010
    ..A virological response was sustained for 6 and 5 months in 2 patients after Peg-IFN-alpha-2a therapy was completed. A relapse was observed in the third patient...
  14. doi request reprint Hepatitis E virus excretion can be prolonged in patients with hematological malignancies
    Suzanne Tavitian
    Service d Hematologie, CHU de Toulouse, Hopital Purpan, Place du Dr Baylac, 31059 Toulouse Cedex, France
    J Clin Virol 49:141-4. 2010
    ..Chronic hepatitis E virus infections have been recently described in solid organ transplant recipients. There is little data on the evolution of hepatitis E in patients immunocompromised for other reasons...
  15. pmc Hepatitis E virus and neurologic disorders
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, Centre Hospitalier Universitaire Rangueil, Toulouse, France
    Emerg Infect Dis 17:173-9. 2011
    ..Neurologic outcomes were complete resolution (n = 3), improvement with residual neurologic deficit (n = 3), and no improvement (n = 1). Neurologic disorders are an emerging extrahepatic manifestation of HEV infection...
  16. ncbi request reprint Hepatitis E virus reinfections in solid-organ-transplant recipients can evolve into chronic infections
    Florence Abravanel
    Centre de Physiopathologie de Toulouse Purpan, INSERM U1043 National Reference Center for Hepatitis E, Laboratoire de Virologie, Institut Fédératif de Biologie, Hopital Purpan
    J Infect Dis 209:1900-6. 2014
    ..Hepatitis E virus (HEV) infections are a major cause of acute hepatitis in developing and industrialized countries. Little is known about anti-HEV immunity in solid-organ recipients...
  17. ncbi request reprint Screening of blood from potential organ and cornea donors for viruses
    Marcel Miedouge
    Laboratoire de Virologie, Hopital Purpan, CHU Toulouse, Toulouse, France
    J Med Virol 66:571-5. 2002
    ..The extraction procedures on post-mortem specimens and/or blood collection must be changed to improve the performance of nucleic acid tests...
  18. doi request reprint Influence of immunosuppressive therapy on the natural history of genotype 3 hepatitis-E virus infection after organ transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, CHU Rangueil, Toulouse, France
    Transplantation 89:353-60. 2010
    ..Hepatitis-E virus (HEV) infection can be responsible for chronic hepatitis in solid-organ transplant patients...
  19. doi request reprint Low risk of hepatitis E virus reactivation after haematopoietic stem cell transplantation
    Florence Abravanel
    INSERM, U1043, Centre de Physiopathologie de Toulouse Purpan, Toulouse, F 31300 France
    J Clin Virol 54:152-5. 2012
    ..HEV infection can evolve to chronic hepatitis in immunocompromised patients. Additionally, HEV reactivation after haematopoietic stem cell transplantation has been reported...
  20. ncbi request reprint Acute hepatitis and renal function impairment related to infection by hepatitis E virus in a renal allograft recipient
    Nassim Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse, France
    Am J Kidney Dis 45:193-6. 2005
    ....
  21. doi request reprint Comparison of 2 highly automated nucleic acid extraction systems for quantitation of human cytomegalovirus in whole blood
    Catherine Mengelle
    Department of Virology, Federative Institute of Biology, 31059 Toulouse, France
    Diagn Microbiol Infect Dis 69:161-6. 2011
    ..49 log(10) copies/mL) with COBAS Ampliprep than with MagNA Pure extraction system. Both MagNA Pure and COBAS Ampliprep provide reliable and high-throughput platforms for real-time PCR HCMV quantitation of DNA extracted from whole blood...
  22. doi request reprint [Hepatitis E infection in dialysis and after transplantation]
    Nassim Kamar
    Service de Nephrologie, dialyse et transplantation multi organes, CHU Rangueil, TSA 50032, 31059 Toulouse Cedex 9, France
    Nephrol Ther 6:83-7. 2010
    ..The reduction of immunosuppressive drugs could be considered as a first-line therapeutic option...
  23. doi request reprint Hepatitis E virus and chronic hepatitis in organ-transplant recipients
    Nassim Kamar
    Department of Nephrology, Dialysis, and Multiorgan Transplantation, Centre Hospitalier Universitaire, Rangueil, France
    N Engl J Med 358:811-7. 2008
    ..The time from transplantation to diagnosis was significantly shorter and the total counts of lymphocytes and of CD2, CD3, and CD4 T cells were significantly lower in patients in whom chronic disease developed...
  24. ncbi request reprint [Hepatitis E virus: an emerging disease]
    Jean Marie Peron
    Service d Hepato gastro enterologie, Fédération Digestive, Hopital Purpan, CHU Toulouse
    Sante 16:239-43. 2006
    ..The diagnosis of hepatitis E must now be considered in any cases of acute hepatitis of unexplained origin in France. Diagnosis relies on RT-PCR testing of blood or stool...