Research Topics
Species | Sylvain ManfrediSummaryCountry: France Publications
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Detail Information
Publications
Complete response of an initially non-surgical adenocarcinoma of the duodenum to chemotherapy with the FOLFOX 4 regimenSylvain Manfredi
Service des Maladies de l Appareil digestif, CHU Pontchaillou, 2 rue H le Guilloux, 35033 Rennes Cedex, France
J Gastrointest Surg 13:2309-13. 2009..No standard chemotherapy is defined for non-surgical adenocarcinoma of the small bowel. In France, it is usually treated with the same chemotherapy regimens as used for colorectal cancer...
Type 1 and 2 gastric carcinoid tumors: long-term follow-up of the efficacy of treatment with a slow-release somatostatin analogueSylvain Manfredi
Gastroenterology Unit, University Hospital Pontchaillou, Rennes, France
Eur J Gastroenterol Hepatol 19:1021-5. 2007..Slow-release somatostatin analogue represents an alternative to repeated endoscopic treatment or high-risk surgery...
Colonoscopy results of a French regional FOBT-based colorectal cancer screening program with high complianceS Manfredi
Service des Maladies de l Appareil digestif, Hopital Pontchaillou, Rennes, France
Endoscopy 40:422-7. 2008..We report the colonoscopy results in one of the first areas to be screened (Ille et Vilaine)...
The positive predictive value of guaiac faecal occult blood test in relation to the number of positive squares in two consecutive rounds of colorectal cancer screeningSylvain Manfredi
Service des Maladies de l Appareil digestif, CHU Pontchaillou, Rennes, France
Eur J Cancer Prev 20:277-82. 2011..Performing a complete colonoscopy in every individual having a positive test, especially aged men with a high number of positive squares, should be a priority in any screening programme...
Variations between endoscopists in rates of detection of colorectal neoplasia and their impact on a regional screening program based on colonoscopy after fecal occult blood testingJean François Bretagne
Department of Gastroenterology, Centre Hospitalo Universitaire, Rennes, France
Gastrointest Endosc 71:335-41. 2010..There are few data about the performance variability among endoscopists participating to nationwide or regionwide colorectal cancer screening programs...
Neoplasia detection rates after positive fecal occult blood test results are not affected by endoscopy center: a population-based studyJean François Bretagne
Department of Gastroenterology, Pontchaillou Hospital, Rennes, France
Gastrointest Endosc 74:141-7. 2011..We previously showed a significant variability in adenoma detection among colonoscopists who were participating in a mass screening program. The reasons for such variability remain largely unknown...
[Colorectal cancer mass screening: present and future]Jean François Bretagne
Service des Maladies de l Appareil digestif, Hopital Pontchaillou, Rennes
Presse Med 36:1054-63. 2007..The medicoeconomic data will be a decisive factor in the choice between these new strategies...
Yield of high-grade dysplasia based on polyp size detected at colonoscopy: a series of 2295 examinations following a positive fecal occult blood test in a population-based studyJean François Bretagne
Service des Maladies de l Appareil digestif, Centre Hospitalo Universitaire, Rennes, France
Dis Colon Rectum 53:339-45. 2010..The aim was to determine the rate of high-grade dysplasia among patients with all adenomas, and its prevalence in patients with adenomas of different sizes in a well-defined population-based study...
Review in depth and meta-analysis of controlled trials on colorectal cancer screening by faecal occult blood testDenis Heresbach
Department of Gastroenterology, Service des Maladies de l Appareil digestif, CHU Pontchaillou, 35033 Rennes, France
Eur J Gastroenterol Hepatol 18:427-33. 2006..These trials have different designs, especially concerning FOBT frequency and duration, as well as the length of follow-up after stopping FOBT campaigns...
[Cost-effectiveness of colorectal cancer screening]Denis Heresbach
Service des Maladies de l Appareil digestif, Hopital Pontchaillou, Rennes
Gastroenterol Clin Biol 30:44-58. 2006....
Chemotherapy for inoperable advanced or metastatic cholangiocarcinoma: retrospective analysis of 78 cases in a single center over four yearsMarc Pracht
Medical Oncology Unit, Comprehensive Cancer Center Eugène Marquis, Rennes, France
Chemotherapy 58:134-41. 2012..According to phase II and III trials, regimens combining 5-fluorouracil (5FU) or gemcitabine with a platinum salt have provided an overall response rate of 12-50% with a median overall survival of 5-16 months...
A national survey of endoscopic mucosal resection for superficial gastrointestinal neoplasiaD Heresbach
Observatoire de la Mucosectomie Endoscopique en Gastroenterologie OMEGA, under the aegis of the Société Française d Endoscopie Digestive SFED, Paris, France
Endoscopy 42:806-13. 2010..Studies on endoscopic mucosal resection (EMR) are mostly based on data from centers with high expertise. We report the average EMR results in a national survey of consecutive patients in France...
Colorectal adenomatous polyposis Associated with MYH mutations: genotype and phenotype characteristicsGuillaume Bouguen
Service des Maladies de l Appareil digestif, Centre Hospitalier Universitaire Pontchaillou, 2 rue Henri Le Guilloux, Rennes, France
Dis Colon Rectum 50:1612-7. 2007..This study was designed to establish the prevalence of germ-line MYH mutations in a series of 56 consecutive patients with no detectable APC mutation and describe the phenotype of those with MYH mutations...
Patients with sporadic duodenal adenoma are a high-risk group for advanced colorectal neoplasia: results of a case-control studyP Pequin
Service des Maladies de l Appareil digestif, Hopital Pontchaillou, Rennes, France
Aliment Pharmacol Ther 26:277-82. 2007..To evaluate colorectal cancer risk among patients with sporadic duodenal neoplasia using a case-control protocol...
[Epidemiology of colorectal cancer liver metastases]Jean Faivre
INSERM EPI 0106, , BP 87900-21079 Dijon
Bull Acad Natl Med 187:815-22; discussion 822-3. 2003..Population based data indicates that liver metastases from colorectal cancer represent a frequent problem and are more frequent that suggested by hospital-based data...
[What role can the hepato-gastroenterologist play in gastro-intestinal oncology?]Jean François Bretagne
Gastroenterol Clin Biol 30:1241-3. 2006
Incidence and management of primary malignant small bowel cancers: a well-defined French population studyCome Lepage
Faculte de Medecine, Registre Bourguignon des Cancers Digestifs, INSERM EMI 0106, Dijon, France
Am J Gastroenterol 101:2826-32. 2006..Few data are available from population-based statistics on small bowel cancers. The aim of this study was to report on their incidence and management...
Epidemiology and management of liver metastases from colorectal cancerSylvain Manfredi
Registre Bourguignon des Cancers Digestifs, , Dijon Cedex, France
Ann Surg 244:254-9. 2006..6% and 6.1% for metachronous liver metastases. CONCLUSION: Liver metastases from colorectal cancer remain a substantial problem. More effective treatments and mass screening represent promising approaches to decrease this problem...
Trends in incidence and management of esophageal adenocarcinoma in a well-defined populationCome Lepage
Registre Bourguignon des Cancers Digestifs, INSERM EPI 0106
Gastroenterol Clin Biol 29:1258-63. 2005..Little epidemiological data is available concerning esophageal adenocarcinomas in France. The aim of this study was to study epidemiological characteristics and management of esophageal adenocarcinoma in a well-defined population...
[The natural history of colorectal cancer revisited]Anne-Marie Bouvier
Registre Bourguignon des Cancers Digestifs, EPI INSERM 0106, , BP 87900, 21079 Dijon Cedex. E-mail
Gastroenterol Clin Biol 26:B56-61. 2002
