Charles Edouard Luyt

Summary

Country: France

Publications

  1. ncbi request reprint Does invasive diagnosis of nosocomial pneumonia during off-hours delay treatment?
    Charles Edouard Luyt
    Universite Pierre et Marie Curie, Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 47 Boulevard de l Hopital, 75651, Paris Cedex 13, France
    Intensive Care Med 33:734-7. 2007
  2. doi request reprint Outcomes and long-term quality-of-life of patients supported by extracorporeal membrane oxygenation for refractory cardiogenic shock
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris 6, Paris, France
    Crit Care Med 36:1404-11. 2008
  3. doi request reprint Aerosolized antibiotics to treat ventilator-associated pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, 47 83 boulevard de l Hopital, Paris Cedex 13, France
    Curr Opin Infect Dis 22:154-8. 2009
  4. pmc Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Université Paris Pierre et Marie Curie, 75651 Paris Cedex 13, France
    Crit Care 13:R200. 2009
  5. doi request reprint Delivering antibiotics to the lungs of patients with ventilator-associated pneumonia: an update
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Expert Rev Anti Infect Ther 11:511-21. 2013
  6. doi request reprint Virus-induced acute respiratory distress syndrome: epidemiology, management and outcome
    Charles Edouard Luyt
    Assistance Publique Hopitaux de Paris, Universite Paris 6 Pierre et Marie Curie, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Service de Reanimation Medicale, 75651 Paris Cedex 13, France
    Presse Med 40:e561-8. 2011
  7. doi request reprint Diffusion tensor imaging to predict long-term outcome after cardiac arrest: a bicentric pilot study
    Charles Edouard Luyt
    Service de Reanimation, School of Medicine, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Université Paris Pierre et Marie Curie, Paris, France
    Anesthesiology 117:1311-21. 2012
  8. ncbi request reprint Long-term outcomes of pandemic 2009 influenza A(H1N1)-associated severe ARDS
    Charles Edouard Luyt
    Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hôpitaux de Paris et Université Paris 6 Pierre et Marie Curie, Paris, France
    Chest 142:583-92. 2012
  9. doi request reprint Usefulness of cardiac biomarkers to predict cardiac recovery in patients on extracorporeal membrane oxygenation support for refractory cardiogenic shock
    Charles Edouard Luyt
    Service de Reanimation, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Paris, France
    J Crit Care 27:524.e7-14. 2012
  10. doi request reprint Usefulness of procalcitonin for the diagnosis of ventilator-associated pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Universite Paris 6, 75651, Paris Cedex 13, France
    Intensive Care Med 34:1434-40. 2008

Detail Information

Publications56

  1. ncbi request reprint Does invasive diagnosis of nosocomial pneumonia during off-hours delay treatment?
    Charles Edouard Luyt
    Universite Pierre et Marie Curie, Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 47 Boulevard de l Hopital, 75651, Paris Cedex 13, France
    Intensive Care Med 33:734-7. 2007
    ..m. to 8:29 a.m. the next day for night shifts, from Saturday 1:00 p.m. to Monday 8:29 a.m. for weekends, and from 8:30 a.m. to 8:29 a.m. the following morning for public holidays)...
  2. doi request reprint Outcomes and long-term quality-of-life of patients supported by extracorporeal membrane oxygenation for refractory cardiogenic shock
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris 6, Paris, France
    Crit Care Med 36:1404-11. 2008
    ..To assess the outcomes and long-term quality-of-life of patients supported by extracorporeal membrane oxygenation (ECMO) for refractory cardiogenic shock...
  3. doi request reprint Aerosolized antibiotics to treat ventilator-associated pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, 47 83 boulevard de l Hopital, Paris Cedex 13, France
    Curr Opin Infect Dis 22:154-8. 2009
    ..This review summarizes the recent data on antibiotic aerosolization to treat ventilator-associated pneumonia...
  4. pmc Pharmacokinetics and lung delivery of PDDS-aerosolized amikacin (NKTR-061) in intubated and mechanically ventilated patients with nosocomial pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Université Paris Pierre et Marie Curie, 75651 Paris Cedex 13, France
    Crit Care 13:R200. 2009
    ....
  5. doi request reprint Delivering antibiotics to the lungs of patients with ventilator-associated pneumonia: an update
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 47 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Expert Rev Anti Infect Ther 11:511-21. 2013
    ....
  6. doi request reprint Virus-induced acute respiratory distress syndrome: epidemiology, management and outcome
    Charles Edouard Luyt
    Assistance Publique Hopitaux de Paris, Universite Paris 6 Pierre et Marie Curie, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Service de Reanimation Medicale, 75651 Paris Cedex 13, France
    Presse Med 40:e561-8. 2011
    ..Ganciclovir can be considered for patients with ARDS and histology- or cytology-proven CMV pneumonia...
  7. doi request reprint Diffusion tensor imaging to predict long-term outcome after cardiac arrest: a bicentric pilot study
    Charles Edouard Luyt
    Service de Reanimation, School of Medicine, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Université Paris Pierre et Marie Curie, Paris, France
    Anesthesiology 117:1311-21. 2012
    ..The authors' objective was to determine whether an assessment with diffusion tensor imaging, a brain magnetic resonance imaging sequence, increases the accuracy of 1 yr functional outcome prediction in cardiac arrest survivors...
  8. ncbi request reprint Long-term outcomes of pandemic 2009 influenza A(H1N1)-associated severe ARDS
    Charles Edouard Luyt
    Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hôpitaux de Paris et Université Paris 6 Pierre et Marie Curie, Paris, France
    Chest 142:583-92. 2012
    ..The objective of this study was to compare the 1-year outcomes of survivors of A(H1N1)-associated ARDS, according to use or no use of extracorporeal lung assist (ECLA), using its need as an ARDS severity surrogate...
  9. doi request reprint Usefulness of cardiac biomarkers to predict cardiac recovery in patients on extracorporeal membrane oxygenation support for refractory cardiogenic shock
    Charles Edouard Luyt
    Service de Reanimation, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Paris, France
    J Crit Care 27:524.e7-14. 2012
    ....
  10. doi request reprint Usefulness of procalcitonin for the diagnosis of ventilator-associated pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Universite Paris 6, 75651, Paris Cedex 13, France
    Intensive Care Med 34:1434-40. 2008
    ..To assess the predictive capacity for the diagnosis of ventilator-associated pneumonia (VAP) of serum procalcitonin levels before and on the day it is suspected...
  11. doi request reprint Viral infections in the ICU
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Paris, and Université Paris 6 Pierre et Marie Curie, France
    Curr Opin Crit Care 14:605-8. 2008
    ..The present study reviews the precise role of viruses as causes of pneumonia in mechanically ventilated patients...
  12. doi request reprint Value of the serum procalcitonin level to guide antimicrobial therapy for patients with ventilator-associated pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Semin Respir Crit Care Med 32:181-7. 2011
    ..Accordingly, for VAP patients, procalcitonin may be used to stop antibiotics as early as day 3 after their initiation, if its concentration is <0.5 ng/mL or has decreased by ≥80%, compared with the first peak concentration...
  13. ncbi request reprint Herpes simplex virus lung infection in patients undergoing prolonged mechanical ventilation
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Université de Paris Pierre et Marie Curie, Assistance Publique Hopitaux de Paris, Paris Cedex 13, France
    Am J Respir Crit Care Med 175:935-42. 2007
    ....
  14. doi request reprint Biomarkers to optimize antibiotic therapy for pneumonia due to multidrug-resistant pathogens
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, France
    Clin Chest Med 32:431-8. 2011
    ..5 ng/mL or has decreased by 80% or more compared with the peak concentration, antibiotics can be stopped. With this strategy, extreme vigilance must be maintained after terminating antimicrobial therapy to detect a recurrent infection...
  15. ncbi request reprint Impact of methicillin resistance on outcome of Staphylococcus aureus ventilator-associated pneumonia
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, 75651 Paris Cedex 13, France
    Am J Respir Crit Care Med 170:786-92. 2004
    ....
  16. doi request reprint Outcomes, long-term quality of life, and psychologic assessment of fulminant myocarditis patients rescued by mechanical circulatory support
    Mariana Mirabel
    Service de Reanimation Medicale, Institut de Cardiologie, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Crit Care Med 39:1029-35. 2011
    ....
  17. ncbi request reprint Impact of antibiotic-resistant bacteria on the outcome of ventilator-associated pneumonia
    Alain Combes
    Service de Reanimation Medicale, Pr Gibert, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Semin Respir Crit Care Med 27:23-8. 2006
    ....
  18. doi request reprint Nosocomial infections in adult cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation
    Matthieu Schmidt
    Service de Reanimation Medicale, Institut de Cardiologie, Paris Cedex 13, France
    Clin Infect Dis 55:1633-41. 2012
    ..Incidence and impact on adult patients' outcomes of nosocomial infections (NIs) occurring during venoarterial extracorporeal membrane oxygenation (VA-ECMO) support for refractory cardiogenic shock have rarely been described...
  19. ncbi request reprint Early predictors for infection recurrence and death in patients with ventilator-associated pneumonia
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris 6, France
    Crit Care Med 35:146-54. 2007
    ..The objective of this study was to describe resolution of VAP variables and to determine early predictors of VAP recurrence and death...
  20. ncbi request reprint Procalcitonin kinetics as a prognostic marker of ventilator-associated pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, 47, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Am J Respir Crit Care Med 171:48-53. 2005
    ..Multivariate analyses retained serum procalcitonin levels on Days 1, 3, and 7 as strong predictors of unfavorable outcome. Based on these data, procalcitonin could be a prognostic marker of outcome during VAP...
  21. ncbi request reprint Value of the clinical pulmonary infection score for the identification and management of ventilator-associated pneumonia
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Intensive Care Med 30:844-52. 2004
    ....
  22. doi request reprint Venoarterial extracorporeal membrane oxygenation support for refractory cardiovascular dysfunction during severe bacterial septic shock
    Nicolas Bréchot
    Service de Reanimation Medicale, Institut de Cardiologie, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Crit Care Med 41:1616-26. 2013
    ....
  23. doi request reprint Early percutaneous tracheotomy versus prolonged intubation of mechanically ventilated patients after cardiac surgery: a randomized trial
    Jean Louis Trouillet
    Institut de Cardiologie, Hopital de la Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Institut National de la Sante et de la Recherche Medicale, Paris, France
    Ann Intern Med 154:373-83. 2011
    ..Whether early percutaneous tracheotomy in patients who require prolonged mechanical ventilation can shorten mechanical ventilation duration and lower mortality remains controversial...
  24. ncbi request reprint Impact of tracheotomy on sedative administration, sedation level, and comfort of mechanically ventilated intensive care unit patients
    Ania Nieszkowska
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Paris, France
    Crit Care Med 33:2527-33. 2005
    ..To assess the impact of tracheotomy on sedative administration, sedation level, and autonomy of mechanically-ventilated intensive care unit (ICU) patients...
  25. ncbi request reprint New diagnostic and prognostic markers of ventilator-associated pneumonia
    Jean Chastre
    Medical Intensive Care Unit, Pitie Salpetriere Hospital, Pierre and Marie Curie University, Paris, France
    Curr Opin Crit Care 12:446-51. 2006
    ..The purpose of this review is to analyze the potential advantages and drawbacks of using biomarkers of bacterial infection for the diagnosis and prognosis of ventilator-associated pneumonia...
  26. ncbi request reprint Adverse effect on a referral intensive care unit's performance of accepting patients transferred from another intensive care unit
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Paris, France
    Crit Care Med 33:705-10. 2005
    ..To determine whether observed and predicted mortality for intensive care unit (ICU) transfer admissions is different from non-ICU transfer admissions and how that might affect ICU performance evaluation...
  27. ncbi request reprint Impact of piperacillin resistance on the outcome of Pseudomonas ventilator-associated pneumonia
    Alain Combes
    Groupe Hospitalier Pitie Salpetriere, Assistance Publique, Hôpitaux de Paris Université Pierre et Marie Curie, Paris 6, Service de Reanimation Medicale, Institut de Cardiologie, Paris, France
    Intensive Care Med 32:1970-8. 2006
    ....
  28. ncbi request reprint Use of quantitative cultures and reduced duration of antibiotic regimens for patients with ventilator-associated pneumonia to decrease resistance in the intensive care unit
    Jean Chastre
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, 75651 Paris Cedex 13, France
    Clin Infect Dis 43:S75-81. 2006
    ....
  29. ncbi request reprint Is tracheostomy associated with better outcomes for patients requiring long-term mechanical ventilation?
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Crit Care Med 35:802-7. 2007
    ..To evaluate the effect of tracheostomy on intensive care unit (ICU) and in-hospital mortality for patients requiring prolonged (> 3 days) mechanical ventilation (MV)...
  30. doi request reprint Predictors of successful extracorporeal membrane oxygenation (ECMO) weaning after assistance for refractory cardiogenic shock
    Nadia Aissaoui
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Universite Pierre et Marie Curie, Paris 6, Paris, France
    Intensive Care Med 37:1738-45. 2011
    ..This study evaluated a weaning strategy following support for refractory cardiogenic shock to identify clinical, hemodynamic, and Doppler echocardiography parameters associated with successful ECMO removal...
  31. doi request reprint Predictive risk factors for primary graft failure requiring temporary extra-corporeal membrane oxygenation support after cardiac transplantation in adults
    Cosimo D'Alessandro
    Universite Pierre et Marie Curie, Paris VI, APHP, Groupe Hospitalier Pitie Salpetriere, Institute of Cardiology, Division of Thoracic and Cardiovascular Surgery, Paris, France
    Eur J Cardiothorac Surg 40:962-9. 2011
    ..We investigated the predictive risk factors for severe PGF that require extra-corporeal membrane oxygenation (ECMO) circulatory support after cardiac transplantation...
  32. doi request reprint Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial
    Lila Bouadma
    Service de Reanimation Medicale, Universite Paris 7 Denis Diderot, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Paris, France
    Lancet 375:463-74. 2010
    ..We aimed to establish the effectiveness of an algorithm based on the biomarker procalcitonin to reduce antibiotic exposure in this setting...
  33. doi request reprint Controversies in ventilator-associated pneumonia
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Semin Respir Crit Care Med 31:47-54. 2010
    ....
  34. doi request reprint Diagnostic techniques and procedures for establishing the microbial etiology of ventilator-associated pneumonia for clinical trials: the pros for quantitative cultures
    Jean Chastre
    Service de Reanimation Medicale, Institut de Cardiologie, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Clin Infect Dis 51:S88-92. 2010
    ....
  35. doi request reprint Prolonged mechanical ventilation after cardiac surgery: outcome and predictors
    Jean Louis Trouillet
    Service de Reanimation Medicale, Institut de Cardiologie, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Paris 6 Pierre et Marie Curie, Paris, France
    J Thorac Cardiovasc Surg 138:948-53. 2009
    ..Our objective was to identify patients still requiring mechanical ventilation 3 days after the operation and those successfully weaned by day 10 to avoid needless and potentially hazardous interventions, such as tracheostomy...
  36. doi request reprint Pharmacokinetics and tolerability of amikacin administered as BAY41-6551 aerosol in mechanically ventilated patients with gram-negative pneumonia and acute renal failure
    Charles Edouard Luyt
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Paris, France
    J Aerosol Med Pulm Drug Deliv 24:183-90. 2011
    ..Given the predominantly renal clearance of aminoglycosides, understanding systemic amikacin exposure and safety during administration of BAY41-6551 to patients with acute renal failure (ARF) is clinically important...
  37. ncbi request reprint Mortality among patients admitted to intensive care units during weekday day shifts compared with "off" hours
    Charles Edouard Luyt
    Service de Reanimation Medicale, Institut de Cardiologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Crit Care Med 35:3-11. 2007
    ....
  38. ncbi request reprint The invasive (quantitative) diagnosis of ventilator-associated pneumonia
    Jean Chastre
    Service de Reanimation Medicale, Institut de Cardiologie, Hopital Pitie Salpetriere, 43 87 bd de l Hôpital, 75651 Paris Cedex 13, France
    Respir Care 50:797-807; discussion 807-12. 2005
    ..Bronchoalveolar lavage may also provide useful clues for the diagnosis of other forms of respiratory failure, such as pulmonary hemorrhage or other types of infections, especially in immunocompromised patients...
  39. doi request reprint Gender impact on the outcomes of critically ill patients with nosocomial infections
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Crit Care Med 37:2506-11. 2009
    ..Highly controversial data exist regarding gender-related differences in outcomes of severe nosocomial infections, reflecting potential confounders related to case-mixes or heterogeneity of populations evaluated...
  40. doi request reprint Impact of extracorporeal membrane oxygenation and continuous venovenous hemodiafiltration on the pharmacokinetics of oseltamivir carboxylate in critically ill patients with pandemic (H1N1) influenza
    Florian Lemaître
    Pharmacy Department, Pitie Salpetriere Hospital, Assistance Publique des Hopitaux de Paris, AP HP, Paris, France
    Ther Drug Monit 34:171-5. 2012
    ..This study was designed to evaluate the impact of ECMO and CVVHDF on the pharmacokinetics of oseltamivir carboxylate (OC) in critically ill patients with pandemic (H1N1) influenza treated with oseltamivir...
  41. doi request reprint Extracorporeal membrane oxygenation for 2009 influenza A (H1N1) acute respiratory distress syndrome: single-centre experience with 1-year follow-up
    Sylvain Beurtheret
    Division of Cardiac Surgery, Pitie Salpetriere Hospital, University Pierre et Marie Curie, Paris, France
    Eur J Cardiothorac Surg 41:691-5. 2012
    ..The use of extracorporeal membrane oxygenation (ECMO) could be advocated as therapeutic solution. We present our experience with ECMO utilized in patients with influenza A (H1N1)-associated respiratory failure...
  42. doi request reprint Extra-corporeal membrane oxygenation temporary support for early graft failure after cardiac transplantation
    Cosimo D'Alessandro
    Universite Pierre et Marie Curie, Paris VI, APHP, Groupe Hospitalier Pitie Salpetriere, Institute of Cardiology, Division of Thoracic and Cardiovascular Surgery, F 75013 Paris, France
    Eur J Cardiothorac Surg 37:343-9. 2010
    ..Early graft failure (EGF) is a major risk for death after heart transplantation. We studied the impact of an extra-corporeal membrane oxygenation (ECMO) temporary support on the operative mortality and the mean-term survival after EGF...
  43. ncbi request reprint Estimation of left ventricular systolic function by single transpulmonary thermodilution
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, 47, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Intensive Care Med 30:1377-83. 2004
    ..The global cardiac systolic function may be decreased despite preserved left ventricular function in this situation.)..
  44. doi request reprint The PRESERVE mortality risk score and analysis of long-term outcomes after extracorporeal membrane oxygenation for severe acute respiratory distress syndrome
    Matthieu Schmidt
    Medical Surgical Intensive Care Unit, iCAN, Institute of Cardiometabolism and Nutrition, Service de Reanimation Medicale, Groupe Hôpital de la Pitié Salpêtrière, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris 6, 47, Bd de l Hopital, 75651, Paris Cedex 13, France
    Intensive Care Med 39:1704-13. 2013
    ..We also assessed long-term survivors' health-related quality of life (HRQL), respiratory symptoms, and anxiety, depression and post-traumatic stress disorder (PTSD) frequencies...
  45. doi request reprint Blood oxygenation and decarboxylation determinants during venovenous ECMO for respiratory failure in adults
    Matthieu Schmidt
    Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Institute of Cardiometabolism and Nutrition ICAN, Assistance Publique Hôpitaux de Paris Université Pierre et Marie Curie, Paris 6, France
    Intensive Care Med 39:838-46. 2013
    ....
  46. doi request reprint Other therapeutic modalities and practices: implications for clinical trials of hospital-acquired or ventilator-associated pneumonia
    Jean Chastre
    Service de Reanimation Medicale, Institut de Cardiologie, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Clin Infect Dis 51:S54-8. 2010
    ..Until results of these trials are known, antibiotic aerosolization can be recommended only for treating patients with multidrug-resistant VAP, for which no effective intravenous regimen is available...
  47. pmc Massive intraventricular thrombus complicating extracorporeal membrane oxygenation support
    Ghassan Moubarak
    Service de Reanimation Medicale, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris, France
    Can J Cardiol 24:e1. 2008
  48. ncbi request reprint Brain natriuretic peptide: A marker of myocardial dysfunction and prognosis during severe sepsis
    Julien Charpentier
    Medical Intensive Care Unit, Groupe Hospitalier Cochin Saint Vincent de Paul La Roche Guyon, Paris, France
    Crit Care Med 32:660-5. 2004
    ..To investigate the value of brain natriuretic peptide plasma levels as a marker of systolic myocardial dysfunction during severe sepsis and septic shock...
  49. doi request reprint Pharmacokinetics and safety of panobacumab: specific adjunctive immunotherapy in critical patients with nosocomial Pseudomonas aeruginosa O11 pneumonia
    Qin Lu
    Multidisciplinary Intensive Care Unit, Department of Anesthesiology, La Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris, UPMC Paris 6, France
    J Antimicrob Chemother 66:1110-6. 2011
    ..Nosocomial Pseudomonas aeruginosa pneumonia remains a major concern in critically ill patients. We explored the potential impact of microorganism-targeted adjunctive immunotherapy in such patients...
  50. doi request reprint Out-of-hospital extra-corporeal life support implantation during refractory cardiac arrest in a half-marathon runner
    Guillaume Lebreton
    Service de Chirurgie Cardio Thoracique, Hopital Pitie Salpetriere, Universite Pierre et Marie Curie Paris 6, Paris, France
    Resuscitation 82:1239-42. 2011
    ..The cardiogenic shock resolved progressively, enabling ECLS weaning within 48h, while renal, hepatic, and respiratory functions recovered simultaneously...
  51. doi request reprint Early corticosteroids in severe influenza A/H1N1 pneumonia and acute respiratory distress syndrome
    Christian Brun-Buisson
    Université Paris Est Créteil and INSERM U955, Creteil, France
    Am J Respir Crit Care Med 183:1200-6. 2011
    ..Despite their controversial role, corticosteroids are often administered to patients with adult respiratory distress syndrome (ARDS) secondary to viral pneumonia...
  52. doi request reprint Acute lung injury after mechanical circulatory support implantation in patients on extracorporeal life support: an unrecognized problem
    David Boulate
    Assistance Publique Hopitaux de Paris, Department of Cardiac and Thoracic Surgery, Cardiologic Institute, hôpital La Pitié Salpêtrière, Paris, France
    Eur J Cardiothorac Surg 44:544-50. 2013
    ..The aim of our study was to analyse the frequency, impact on mortality and characteristics of patients presenting ALI after MCS implantation in the bridge-to-bridge (BTB) strategy...
  53. doi request reprint What is the niche for extracorporeal membrane oxygenation in severe acute respiratory distress syndrome?
    Alain Combes
    Service de Reanimation Medicale, Hopital Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie, Paris 6, Paris, France
    Curr Opin Crit Care 18:527-32. 2012
    ..This article reviews the results of case series and trials which evaluated venovenous extracorporeal membrane oxygenation (VV-ECMO) for severe respiratory failure. Potential indications of the technique in this setting are discussed...
  54. ncbi request reprint Circulatory support for fulminant myocarditis: consideration for implantation, weaning and explantation
    Pascal Leprince
    Service de Chirurgie Thoracique et Cardiovasculaire, Groupe Pitié Salpêtrière, Institut de Cardiologie, 47 83 boulevard de l Hopital, 75013 Paris, France
    Eur J Cardiothorac Surg 24:399-403. 2003
    ..Fulminant myocarditis (FM) is an uncommon but life-threatening condition for which a mechanical circulatory support (MCS) device can be life-saving. However, device selection, weaning and explantation procedures remain poorly defined...
  55. pmc High levels of catalytic antibodies correlate with favorable outcome in sepsis
    Sebastien Lacroix-Desmazes
    Institut National de la Sante et de la Recherche Medicale, Unite 681, Universite Paris VI, Institut des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Proc Natl Acad Sci U S A 102:4109-13. 2005
    ..Our observations provide the first evidence that hydrolytic antibodies might play a role in recovery from a disease...
  56. ncbi request reprint Virus diseases in ICU patients: a long time underestimated; but be aware of overestimation
    Charles Edouard Luyt
    Intensive Care Med 32:968-70. 2006