Research Topics
| Jean Christophe LucetSummaryCountry: France Publications
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Publications
Successful long-term program for controlling methicillin-resistant Staphylococcus aureus in intensive care unitsJean Christophe Lucet
Infection Control Unit, Bichat Claude Bernard Teaching Hospital, Assistance Publique Hopitaux de Paris, 75877 Paris Cedex 18, France
Intensive Care Med 31:1051-7. 2005..To evaluate the effectiveness of screening strategy and contact precautions for patients with methicillin-resistant Staphylococcus aureus (MRSA)...- Hand contamination before and after different hand hygiene techniques: a randomized clinical trialJ C Lucet
Infection Control Unit, Bichat Claude Bernard Hospital, Paris, France
J Hosp Infect 50:276-80. 2002..Qualitative assessment showed that 11 of the 256 pre-HH specimens (4.3%) had pathogenic bacteria, and that two of these 11 remained positive after HH (US in both instances)... - [The importance of detecting methicillin-resistant Staphylococcus aureus in an intensive care setting]J C Lucet
Unité d hygiène et de lutte contre l infection nosocomiale, Groupe Hospitalier Bichat Claude Bernard, 46, rue Henri Huchard, 75877 Paris, France
Ann Fr Anesth Reanim 21:384-91. 2002..Such detection has several objectives: the identification of carriers, assistance in the implementation of isolation precautions, the eradication of carriage and the evaluation of strategy. These different objectives are discussed... - Prevalence and risk factors for carriage of methicillin-resistant Staphylococcus aureus at admission to the intensive care unit: results of a multicenter studyJean Christophe Lucet
Unité d hygiène et de lutte contre l infection nosocomiale, Hopital Bichat Claude Bernard, 75877 Paris Cedex 18, France
Arch Intern Med 163:181-8. 2003..Detection of methicillin-resistant Staphylococcus aureus (MRSA) carriers on admission to the intensive care unit (ICU) is an important component of strategies for controlling the spread of MRSA... - High prevalence of carriage of methicillin-resistant Staphylococcus aureus at hospital admission in elderly patients: implications for infection control strategiesJean Christophe Lucet
Infection Control Unit, Bichat Claude Bernard Teaching Hospital, Assistance Publique Jôpitaux de Paris, Paris, France
Infect Control Hosp Epidemiol 26:121-6. 2005..Despite contact isolation precautions for patients with methicillin-resistant Staphylococcus aureus (MRSA), MRSA infections are increasing in many countries... 
Do case vignettes accurately reflect antibiotic prescription?Jean Christophe Lucet
Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, and Université Paris Diderot, Sorbonne Paris Cité, France
Infect Control Hosp Epidemiol 32:1003-9. 2011..Antibiotic prescription is frequently inappropriate in hospitals. Our objective was to evaluate whether the quality of antibiotic prescription could be measured using case vignettes to assess physicians' knowledge...- Acquisition of methicillin-resistant Staphylococcus aureus in the acute care setting: incidence and risk factorsChristophe Rioux
Infectious Diseases Unit, Bichat Claude Bernard Hospital, Paris, France
Infect Control Hosp Epidemiol 28:733-6. 2007..1% of patients who had tested negative for MRSA on admission had cultures positive for MRSA at discharge. Only the presence of chronic skin breaks at admission was independently associated with MRSA acquisition... - Epidemiology of multidrug-resistant bacteria in patients with long hospital staysCagri Buke
Infection Control Unit, Bichat Claude Bernard Teaching Hospital, Paris, France
Infect Control Hosp Epidemiol 28:1255-60. 2007.... - Long-term impact of a multifaceted prevention program on ventilator-associated pneumonia in a medical intensive care unitLila Bouadma
Service de Réanimation Médicale et des Maladies Infectieuses, Hopital Bichat Claude Bernard, Paris, France
Clin Infect Dis 51:1115-22. 2010..We used segmented regression analysis and a Cox proportional hazard model to assess the impact of the program on first VAP occurrence... - Changes in knowledge, beliefs, and perceptions throughout a multifaceted behavioral program aimed at preventing ventilator-associated pneumoniaLila Bouadma
Service de Réanimation Médicale et des Maladies Infectieuses, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Universite Paris 7 Denis Diderot, 46 rue Henri Huchard, 75877 Paris Cedex 18, France
Intensive Care Med 36:1341-7. 2010..This study attempted to assess change of individual factors throughout a multifaceted program focusing on VAP prevention... - Carriage of methicillin-resistant Staphylococcus aureus in home care settings: prevalence, duration, and transmission to household membersJean Christophe Lucet
InfectionControl Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris AP HP, Paris, France
Arch Intern Med 169:1372-8. 2009..However, information is lacking about factors associated with prolonged MRSA colonization and MRSA transmission to household contacts... - A multifaceted program to prevent ventilator-associated pneumonia: impact on compliance with preventive measuresLila Bouadma
Service de Réanimation Médicale et des Maladies Infectieuses, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, Universite Paris 7 Denis Diderot, Paris, France
Crit Care Med 38:789-96. 2010..To determine the effect of a 2-yr multifaceted program aimed at preventing ventilator-acquired pneumonia on compliance with eight targeted preventive measures... 
Electronic sensors for assessing interactions between healthcare workers and patients under airborne precautionsJean Christophe Lucet
Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, France
PLoS ONE 7:e37893. 2012..We used a Radio Frequency Identification Device (RFID) system to automatically measure HCW-patient interactions...- Prospective assessment of hospital-acquired bloosdstream infections: how many may be preventable?Christine Bonnal
Infection Control Unit, Bichat Claude Bernard University Hospital, Assistance Publique Hopitaux de Paris, and Paris VII Denis Diderot University, Paris, France
Qual Saf Health Care 19:e30. 2010..To determine the proportion of preventable hospital-acquired bloodstream infections (HA-BSIs), the authors prospectively examined consecutive cases in a large university hospital over an 18-month period... - Accuracy and potential usefulness of triplex real-time PCR for improving antibiotic treatment of patients with blood cultures showing clustered gram-positive cocci on direct smearsRaymond Ruimy
Hospital Group Bichat Claude Bernard, Laboratoire de Bacteriologie, 46, rue Henri Huchard, 75018 Paris, France
J Clin Microbiol 46:2045-51. 2008..The use of RT-PCR would increase treatment effectiveness in patients with staphylococcal bacteremia and reduce the selective pressure created by glycopeptides... - [Effect of a long-term quality improvement program on the risk of infection related to peripheral venous catheters]Isabelle Lolom
Unité d hygiène et de lutte contre l infection nosocomiale, Hopital Bichat Claude Bernard, Assistance Publique Hopitaux de Paris, et Faculté Denis Diderot Paris VI, F 75000 Paris, France
Presse Med 38:34-42. 2009..Nurses and physicians often underestimate this risk. We describe here a 10-year continuous quality improvement program in a large university hospital... - Bacteriuria in a geriatric hospital: impact of an antibiotic improvement programChristine Bonnal
Infection Control Unit, Bretonneau Teaching Hospital, Assistance Publique Hopitaux de Paris, Paris, France
J Am Med Dir Assoc 9:605-9. 2008..To prospectively evaluate a management approach to bacteriuria including advice from an infectious diseases consultant (IDC) in geriatric inpatients... - Emergence of imipenem-resistant gram-negative bacilli in intestinal flora of intensive care patientsLaurence Armand-Lefevre
French National Reference Center for Bacterial Resistance in Commensal Flora, Laboratory of Bacteriology, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, France
Antimicrob Agents Chemother 57:1488-95. 2013..9 (95% confidence interval [95% CI], 1.5 to 25.7) after 1 to 3 days of exposure and increased to 7.8 (95% CI, 2.4 to 29.8) thereafter. In conclusion, even brief exposure to imipenem is a major risk factor for IR-GNB carriage... - Infectious risk associated with arterial catheters compared with central venous cathetersJean Christophe Lucet
Head of Infection Control Unit, Bichat Claude Bernard University Hospital, Assistance Publique Hopitaux de Paris, Paris
Crit Care Med 38:1030-5. 2010..Arterial catheters are considered at lower risk for catheter-related infection than central venous catheters in the absence of conclusive evidence... - The carriage population of Staphylococcus aureus from Mali is composed of a combination of pandemic clones and the divergent Panton-Valentine leukocidin-positive genotype ST152Raymond Ruimy
Hopital Bichat Claude Bernard, AP HP, EA 3964, Université Denis Diderot Paris 7 Medical School, 75870 Paris Cedex, France
J Bacteriol 190:3962-8. 2008..aureus clone noted mostly in Central Europe. We show that 100% of the ST152 isolates recovered from nasal carriage samples in Mali are PVL positive and discuss implications relating to the emergence and spread of this virulent genotype... - Maternal vaginal colonisation by Staphylococcus aureus and newborn acquisition at deliveryNadège Bourgeois-Nicolaos
Service de Bacteriologie, Hopital Bichat Claude Bernard, AP HP, Paris, France
Paediatr Perinat Epidemiol 24:488-91. 2010..03). No S. aureus colonisation was detected in the mothers of 58% of the colonised newborns suggesting extra-delivery colonisation routes. Consequences for newborns were unclear as only one case of S. aureus neonatal sepsis was observed... - Curbing methicillin-resistant Staphylococcus aureus in 38 French hospitals through a 15-year institutional control programVincent Jarlier
Université Pierre et Marie Curie Hôpital Pitié Salpêtrière, Assistance Publique Hopitaux de Paris, France
Arch Intern Med 170:552-9. 2010..In the late 1980s, the proportion of methicillin resistance among clinical strains of Staphylococcus aureus (MRSA) reached approximately 40% at AP-HP... - Screening and decolonization: does methicillin-susceptible Staphylococcus aureus hold lessons for methicillin-resistant S. aureus?Jean Christophe Lucet
Infection Control Unit, Bichat Claude Bernard University Hospital, Assistance Publique Hopitaux de Paris, Paris, France
Clin Infect Dis 51:585-90. 2010..Screening and decolonization may be effective in decreasing the MRSA infection risk in carriers... - Ventilator-associated pneumonia and its preventionLila Bouadma
Service de Réanimation Médicale et des Maladies Infectieuses, Hopital Bichat Claude Bernard, Paris, France
Curr Opin Infect Dis 25:395-404. 2012..Given that ventilator-associated pneumonia (VAP) causes substantial morbidity, mortality and costs, prevention of this infectious process is a major challenge... - Development of a phenotypic method for detection of fecal carriage of OXA-48-producing enterobacteriaceae after incidental detection from clinical specimenEtienne Ruppe
Centre National de Référence Associé Résistance dans les Flores Commensales, Laboratoire de Bacteriologie, Hopital Bichat Claude Bernard, AP HP, Paris, France
J Clin Microbiol 49:2761-2. 2011.... - Economic evaluation of chlorhexidine-impregnated sponges for preventing catheter-related infections in critically ill adults in the Dressing StudyCarole Schwebel
Medical Intensive Care Unit, Albert Michallon University Hospital Grenoble, France
Crit Care Med 40:11-7. 2012..4‰ to 0.6‰ catheter days, and that scheduled dressing changes every 7 days was not inferior to scheduled changes every 3 days. Here, we assessed the cost benefits of chlorhexidine-impregnated sponge use... - Antibiotic use: knowledge and perceptions in two university hospitalsJean Christophe Lucet
Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, and Denis Diderot University, Paris, France
J Antimicrob Chemother 66:936-40. 2011..To investigate knowledge and perceptions about antibiotic prescription in two university hospitals... - Agreement among health care professionals in diagnosing case Vignette-based surgical site infectionsDidier Lepelletier
Infection Control Unit, Bichat Claude Bernard Hospital, Assistance Publique Hopitaux de Paris, Paris, France
PLoS ONE 7:e35131. 2012..To assess agreement in diagnosing surgical site infection (SSI) among healthcare professionals involved in SSI surveillance... - Personal decision-making criteria related to seasonal and pandemic A(H1N1) influenza-vaccination acceptance among French healthcare workersLila Bouadma
Réanimation Médicale et des Maladies Infectieuses, Hôpital Bichat Claude Bernard Hôpitaux Universitaires Paris Nord Val de Seine, Assistance Publique Hopitaux de Paris, Paris, France
PLoS ONE 7:e38646. 2012..In France, this vaccination is free but administered on a voluntary basis. We investigated the factors influencing HCW influenza vaccination... - Quantification and spread of Pneumocystis jirovecii in the surrounding air of patients with Pneumocystis pneumoniaFiras Choukri
Saint Louis Hospital APHP, Paris Diderot University, Paris, France
Clin Infect Dis 51:259-65. 2010..Our objective is to evaluate P. jirovecii air diffusion in patients with Pneumocystis pneumonia... - Surgical site infection after cardiac surgery: a simplified surveillance methodJean Christophe Lucet
Unité d hygiène et de lutte contre l infection nosocomiale, Hopital Bichat Claude Bernard, Paris, France
Infect Control Hosp Epidemiol 27:1393-6. 2006..The risk factors identified were obesity, age, coronary artery bypass grafting, postoperative mechanical ventilation, and early surgical reexploration. The resource efficiency of this simplified surveillance method is discussed... - Acquisition of multidrug-resistant Pseudomonas aeruginosa in patients in intensive care units: role of antibiotics with antipseudomonal activityElisabeth Paramythiotou
Bacteriology Laboratory, Bichat-Claude Bernard Hospital, Paris Cedex 18, France
Clin Infect Dis 38:670-7. 2004..These data support a major role for the use of antibiotics with high antipseudomonal activity, particularly ciprofloxacin, in the emergence of MDRPA... - Surgical site infection after surgery to repair femoral neck fracture: a French multicenter retrospective studyJacques Merrer
Unite de Lutte contre les Infections Nosocomiales, Centre Hospitalier de Poissy St Germain en Laye, Poissy, France
Infect Control Hosp Epidemiol 28:1169-74. 2007....