Genomes and Genes

Species

Vanessa Louzier

Summary

Country: France

Publications

  1. pmc Pdx-1 or Pdx-1-VP16 protein transduction induces beta-cell gene expression in liver-stem WB cells
    Juliette Cuvelier Delisle
    UMR 707 IECM ENVN, F 44307 Nantes, France
    BMC Res Notes 2:3. 2009
  2. pmc Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation
    Juliette Cuvelier Delisle
    Immuno endocrinology Unit 707, National Veterinary School, F 44300 Nantes, France
    BMC Res Notes 1:136. 2008

Collaborators

  • Juliette Cuvelier Delisle
  • Lionel Martignat
  • Jean Marie Bach
  • Laurence Dubreil
  • Steffi Bösch

Detail Information

Publications2

  1. pmc Pdx-1 or Pdx-1-VP16 protein transduction induces beta-cell gene expression in liver-stem WB cells
    Juliette Cuvelier Delisle
    UMR 707 IECM ENVN, F 44307 Nantes, France
    BMC Res Notes 2:3. 2009
    ..CONCLUSION: These results demonstrate that Pdx-1(-VP16) protein transduction is instrumental for in vitro liver-to-pancreas conversion and is an alternative to gene therapy for beta-cell engineering for diabetes cell therapy...
  2. pmc Bipotential mouse embryonic liver (BMEL) cells spontaneously express Pdx1 and Ngn3 but do not undergo further pancreatic differentiation upon Hes1 down-regulation
    Juliette Cuvelier Delisle
    Immuno endocrinology Unit 707, National Veterinary School, F 44300 Nantes, France
    BMC Res Notes 1:136. 2008
    ..These untransformed mouse embryonic liver cells have been reproducibly isolated from different inbred mice strains and have the potential to differentiate into hepatocytes and cholangiocytes in vitro and in vivo...