Stephane Lourdel

Summary

Country: France

Publications

  1. doi request reprint ClC-5 mutations associated with Dent's disease: a major role of the dimer interface
    Stephane Lourdel
    UPMC Univ Paris 06, UMR_S 872, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, 75005, Paris, France
    Pflugers Arch 463:247-56. 2012
  2. doi request reprint Novel CLCN5 mutations in patients with Dent's disease result in altered ion currents or impaired exchanger processing
    Teddy Grand
    UPMC Universite Paris 06, UMR 7134, Paris, France
    Kidney Int 76:999-1005. 2009
  3. doi request reprint Novel CLCNKB Mutations Causing Bartter Syndrome Affect Channel Surface Expression
    Mathilde Keck
    UPMC Universite Paris 06, UMR_S 872, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, Paris, France INSERM, UMR_S 872, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, Paris, France
    Hum Mutat 34:1269-78. 2013
  4. ncbi request reprint Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis
    Stephane Lourdel
    CNRS UPMC UMR 7134, Institut des Cordeliers, Paris, France
    J Am Soc Nephrol 16:3642-50. 2005
  5. pmc An inward rectifier K(+) channel at the basolateral membrane of the mouse distal convoluted tubule: similarities with Kir4-Kir5.1 heteromeric channels
    Stephane Lourdel
    INSERM U426, Institut Federatif de Recherche 02, Faculte de Medecine Xavier Bichat, Paris, France
    J Physiol 538:391-404. 2002
  6. doi request reprint Heterogeneity in the processing of CLCN5 mutants related to Dent disease
    Teddy Grand
    UPMC Univ Paris 06, UMR_S 872, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, Paris, France
    Hum Mutat 32:476-83. 2011
  7. ncbi request reprint Exploration of the basolateral chloride channels in the renal tubule using
    Jacques Teulon
    UMR 7134 CNRS UPMC, Centre de Recherches Biomedicales des Cordeliers, Paris, France
    Nephron Physiol 99:p64-8. 2005
  8. ncbi request reprint How Bartter's and Gitelman's syndromes, and Dent's disease have provided important insights into the function of three renal chloride channels: ClC-Ka/b and ClC-5
    Marie Briet
    Departementde Physiologie, Hopital Europeen Georges Pompidou, Assistance Publique Hôpitaux de Paris INSERM U 356, IFR 58, and Rene Descartes University and School of Medicine, Paris, France
    Nephron Physiol 103:p7-13. 2006

Collaborators

Detail Information

Publications8

  1. doi request reprint ClC-5 mutations associated with Dent's disease: a major role of the dimer interface
    Stephane Lourdel
    UPMC Univ Paris 06, UMR_S 872, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, 75005, Paris, France
    Pflugers Arch 463:247-56. 2012
    ..Here, we discuss the functional consequences of the three classes of CLCN5 mutations on ClC-5 structure and function...
  2. doi request reprint Novel CLCN5 mutations in patients with Dent's disease result in altered ion currents or impaired exchanger processing
    Teddy Grand
    UPMC Universite Paris 06, UMR 7134, Paris, France
    Kidney Int 76:999-1005. 2009
    ..Thus these mutations have distinct mechanisms by which they could impair ClC-5 function in Dent's disease...
  3. doi request reprint Novel CLCNKB Mutations Causing Bartter Syndrome Affect Channel Surface Expression
    Mathilde Keck
    UPMC Universite Paris 06, UMR_S 872, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, Paris, France INSERM, UMR_S 872, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, Paris, France
    Hum Mutat 34:1269-78. 2013
    ..Overall, two classes of mutants can be distinguished: nonconducting mutants associated with low total protein expression, and partially conducting mutants with unaltered channel properties and ClC-Kb protein abundance. ..
  4. ncbi request reprint Hyperaldosteronemia and activation of the epithelial sodium channel are not required for sodium retention in puromycin-induced nephrosis
    Stephane Lourdel
    CNRS UPMC UMR 7134, Institut des Cordeliers, Paris, France
    J Am Soc Nephrol 16:3642-50. 2005
    ....
  5. pmc An inward rectifier K(+) channel at the basolateral membrane of the mouse distal convoluted tubule: similarities with Kir4-Kir5.1 heteromeric channels
    Stephane Lourdel
    INSERM U426, Institut Federatif de Recherche 02, Faculte de Medecine Xavier Bichat, Paris, France
    J Physiol 538:391-404. 2002
    ..At the current state of knowledge, the channel is similar to Kir4.1-Kir5.1 and Kir4.2-Kir5.1 heteromeric channels, but not to Kir4.1 or Kir4.2 homomeric channels...
  6. doi request reprint Heterogeneity in the processing of CLCN5 mutants related to Dent disease
    Teddy Grand
    UPMC Univ Paris 06, UMR_S 872, Laboratoire de Génomique, Physiologie et Physiopathologie Rénales, Paris, France
    Hum Mutat 32:476-83. 2011
    ..Half of these mutants displayed reduced currents, whereas the other half showed abolished currents. Our study revealed distinct cellular mechanisms accounting for ClC-5 loss of function in Dent disease...
  7. ncbi request reprint Exploration of the basolateral chloride channels in the renal tubule using
    Jacques Teulon
    UMR 7134 CNRS UPMC, Centre de Recherches Biomedicales des Cordeliers, Paris, France
    Nephron Physiol 99:p64-8. 2005
    ..We also discuss the possibility that chloride channels that do not belong to the ClC family may also be involved in the absorption of chloride across the cortical thick ascending limb...
  8. ncbi request reprint How Bartter's and Gitelman's syndromes, and Dent's disease have provided important insights into the function of three renal chloride channels: ClC-Ka/b and ClC-5
    Marie Briet
    Departementde Physiologie, Hopital Europeen Georges Pompidou, Assistance Publique Hôpitaux de Paris INSERM U 356, IFR 58, and Rene Descartes University and School of Medicine, Paris, France
    Nephron Physiol 103:p7-13. 2006
    ....