Ariel B Lindner

Summary

Country: France

Publications

  1. doi request reprint Protein aggregation as a paradigm of aging
    Ariel B Lindner
    INSERM U571, Paris Descartes University, Paris, F 75015, France
    Biochim Biophys Acta 1790:980-96. 2009
  2. pmc Localization of protein aggregation in Escherichia coli is governed by diffusion and nucleoid macromolecular crowding effect
    Anne Sophie Coquel
    Institut National de la Sante et de la Recherche Medicale, Unité 1001, Paris, France
    PLoS Comput Biol 9:e1003038. 2013
  3. pmc Pre-disposition and epigenetics govern variation in bacterial survival upon stress
    Ming Ni
    Institut National de la Sante et de la Recherche Medicale, Paris, France
    PLoS Genet 8:e1003148. 2012
  4. pmc Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation
    Ariel B Lindner
    Institut National de la Sante et de la Recherche Medicale, Unité 571, F 75015 Paris, France
    Proc Natl Acad Sci U S A 105:3076-81. 2008
  5. doi request reprint Direct visualization of horizontal gene transfer
    Ana Babic
    INSERM U571, Paris F 75015, France
    Science 319:1533-6. 2008
  6. doi request reprint Recombination and replication in DNA repair of heavily irradiated Deinococcus radiodurans
    Dea Slade
    Universite Paris Descartes, Faculte de Medecine, INSERM U571, Paris, France
    Cell 136:1044-55. 2009
  7. pmc Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch
    Lydia Robert
    INSERM, and Faculty of Medicine, Paris Descartes University, 24 Rue de Faubourg St Jacques, Paris, France
    Mol Syst Biol 6:357. 2010
  8. pmc Emergence of variability in isogenic Escherichia coli populations infected by a filamentous virus
    Marianne De Paepe
    INSERM, Unité 1001, Génétique Moléculaire Evolutive et Médicale, Paris, France Université Paris Descartes, Paris, France
    PLoS ONE 5:e11823. 2010
  9. pmc Mutations in two global regulators lower individual mortality in Escherichia coli
    Fanette Fontaine
    INSERM, U571, Paris, F 75015, France
    Mol Microbiol 67:2-14. 2008
  10. pmc Dissecting the genetic components of adaptation of Escherichia coli to the mouse gut
    Antoine Giraud
    INSERM, U571, Paris, France
    PLoS Genet 4:e2. 2008

Collaborators

Detail Information

Publications10

  1. doi request reprint Protein aggregation as a paradigm of aging
    Ariel B Lindner
    INSERM U571, Paris Descartes University, Paris, F 75015, France
    Biochim Biophys Acta 1790:980-96. 2009
    ....
  2. pmc Localization of protein aggregation in Escherichia coli is governed by diffusion and nucleoid macromolecular crowding effect
    Anne Sophie Coquel
    Institut National de la Sante et de la Recherche Medicale, Unité 1001, Paris, France
    PLoS Comput Biol 9:e1003038. 2013
    ..They further support the importance of "soft" intracellular structuring (based on macromolecular crowding) in diffusion-based protein localization in E. coli...
  3. pmc Pre-disposition and epigenetics govern variation in bacterial survival upon stress
    Ming Ni
    Institut National de la Sante et de la Recherche Medicale, Paris, France
    PLoS Genet 8:e1003148. 2012
    ..Unlike in a bet-hedging strategy, we observe that cells with a higher investment in maintenance, measured as the basal RpoH transcriptional activity prior to antibiotic treatment, are more likely to give rise to stressed, frail progeny...
  4. pmc Asymmetric segregation of protein aggregates is associated with cellular aging and rejuvenation
    Ariel B Lindner
    Institut National de la Sante et de la Recherche Medicale, Unité 571, F 75015 Paris, France
    Proc Natl Acad Sci U S A 105:3076-81. 2008
    ..This suggests an asymmetric strategy whereby dividing cells segregate damage at the expense of aging individuals, resulting in the perpetuation of the population...
  5. doi request reprint Direct visualization of horizontal gene transfer
    Ana Babic
    INSERM U571, Paris F 75015, France
    Science 319:1533-6. 2008
    ..The incidence of DNA splitting corresponds to about one crossover per cell generation...
  6. doi request reprint Recombination and replication in DNA repair of heavily irradiated Deinococcus radiodurans
    Dea Slade
    Universite Paris Descartes, Faculte de Medecine, INSERM U571, Paris, France
    Cell 136:1044-55. 2009
    ..The present in vivo characterization of key recombination and replication processes dissects the mechanism of DNA repair in heavily irradiated D. radiodurans...
  7. pmc Pre-dispositions and epigenetic inheritance in the Escherichia coli lactose operon bistable switch
    Lydia Robert
    INSERM, and Faculty of Medicine, Paris Descartes University, 24 Rue de Faubourg St Jacques, Paris, France
    Mol Syst Biol 6:357. 2010
    ..Thus, stochasticity at the local level of the network and global physiology are synergistically involved in cell response determination...
  8. pmc Emergence of variability in isogenic Escherichia coli populations infected by a filamentous virus
    Marianne De Paepe
    INSERM, Unité 1001, Génétique Moléculaire Evolutive et Médicale, Paris, France Université Paris Descartes, Paris, France
    PLoS ONE 5:e11823. 2010
    ..Moreover, it naturally reproduces the shift towards higher virulence when the host is experimenting poor conditions, as observed commonly in host-parasite systems...
  9. pmc Mutations in two global regulators lower individual mortality in Escherichia coli
    Fanette Fontaine
    INSERM, U571, Paris, F 75015, France
    Mol Microbiol 67:2-14. 2008
    ..The identification of these two mutants implies that reducing mortality is not impossible; rather, due to its cost, it is subject to trade-offs with other traits that contribute to the competitive success of the organism...
  10. pmc Dissecting the genetic components of adaptation of Escherichia coli to the mouse gut
    Antoine Giraud
    INSERM, U571, Paris, France
    PLoS Genet 4:e2. 2008
    ....