L Letenneur

Summary

Country: France

Publications

  1. pmc Are sex and educational level independent predictors of dementia and Alzheimer's disease? Incidence data from the PAQUID project
    L Letenneur
    Unité INSERM 330, Universite Victor Segalen, Bordeaux, France
    J Neurol Neurosurg Psychiatry 66:177-83. 1999
  2. ncbi request reprint Alcohol and tobacco consumption as risk factors of dementia: a review of epidemiological studies
    Luc Letenneur
    INSERM U 593, Case 11, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
    Biomed Pharmacother 58:95-9. 2004
  3. ncbi request reprint Flavonoid intake and cognitive decline over a 10-year period
    L Letenneur
    INSERM, Unité 593, Bordeaux, France
    Am J Epidemiol 165:1364-71. 2007
  4. pmc Occupation during life and risk of dementia in French elderly community residents
    C Helmer
    INSERM U 330, Universite de Bordeaux II, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    J Neurol Neurosurg Psychiatry 71:303-9. 2001
  5. ncbi request reprint Adherence to a Mediterranean diet and risk of fractures in French older persons
    C Feart
    Univ Bordeaux, ISPED, Centre INSERM U897 Epidemiologie Biostatistique, 33000, Bordeaux, France
    Osteoporos Int 24:3031-41. 2013
  6. ncbi request reprint Neuropsychological correlates of self-reported performance in instrumental activities of daily living and prediction of dementia
    P Barberger-Gateau
    INSERM 330, Universite Victor Segalen, Bordeaux, France
    J Gerontol B Psychol Sci Soc Sci 54:P293-303. 1999
  7. ncbi request reprint Dietary patterns and risk of dementia: the Three-City cohort study
    P Barberger-Gateau
    INSERM, U593, University Victor Segalen Bordeaux 2, Case 11, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    Neurology 69:1921-30. 2007
  8. pmc Analysis of the effect of aluminum in drinking water and transferrin C2 allele on Alzheimer's disease
    V Rondeau
    INSERM EMI 0338, Universite Victor Segalen Bordeaux, Bordeaux, France
    Eur J Neurol 13:1022-5. 2006
  9. ncbi request reprint Oral health condition of French elderly and risk of dementia: a longitudinal cohort study
    E Arrive
    Department of Oral Health, Universite Victor Segalen, Bordeaux, France
    Community Dent Oral Epidemiol 40:230-8. 2012
  10. ncbi request reprint Mortality with dementia: results from a French prospective community-based cohort
    C Helmer
    INSERM U 330, Universite de Bordeaux II, Bordeaux, France
    Am J Epidemiol 154:642-8. 2001

Detail Information

Publications43

  1. pmc Are sex and educational level independent predictors of dementia and Alzheimer's disease? Incidence data from the PAQUID project
    L Letenneur
    Unité INSERM 330, Universite Victor Segalen, Bordeaux, France
    J Neurol Neurosurg Psychiatry 66:177-83. 1999
    ..To examine the age specific risk of Alzheimer's disease according to sex, and to explore the role of education in a cohort of elderly community residents aged 65 years and older...
  2. ncbi request reprint Alcohol and tobacco consumption as risk factors of dementia: a review of epidemiological studies
    Luc Letenneur
    INSERM U 593, Case 11, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
    Biomed Pharmacother 58:95-9. 2004
    ..These results suggest that tobacco consumption is not associated with a lower risk of dementia and that moderate alcohol intake does not increase the risk of developing dementia...
  3. ncbi request reprint Flavonoid intake and cognitive decline over a 10-year period
    L Letenneur
    INSERM, Unité 593, Bordeaux, France
    Am J Epidemiol 165:1364-71. 2007
    ..2 points. This gradient persisted after adjustment for several other potential confounders. This study raises the possibility that dietary flavonoid intake is associated with better cognitive evolution...
  4. pmc Occupation during life and risk of dementia in French elderly community residents
    C Helmer
    INSERM U 330, Universite de Bordeaux II, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    J Neurol Neurosurg Psychiatry 71:303-9. 2001
    ..To determine whether principal occupation during life is a risk factor for incident Alzheimer's disease, vascular dementia, or dementia with parkinsonism...
  5. ncbi request reprint Adherence to a Mediterranean diet and risk of fractures in French older persons
    C Feart
    Univ Bordeaux, ISPED, Centre INSERM U897 Epidemiologie Biostatistique, 33000, Bordeaux, France
    Osteoporos Int 24:3031-41. 2013
    ....
  6. ncbi request reprint Neuropsychological correlates of self-reported performance in instrumental activities of daily living and prediction of dementia
    P Barberger-Gateau
    INSERM 330, Universite Victor Segalen, Bordeaux, France
    J Gerontol B Psychol Sci Soc Sci 54:P293-303. 1999
    ..Only the first factor was predictive of the risk of incident dementia, suggesting that the predictive value of the 4 IADL was explained by their cognitive component...
  7. ncbi request reprint Dietary patterns and risk of dementia: the Three-City cohort study
    P Barberger-Gateau
    INSERM, U593, University Victor Segalen Bordeaux 2, Case 11, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    Neurology 69:1921-30. 2007
    ..The aim of our study was to analyze the relationship between dietary patterns and risk of dementia or Alzheimer disease (AD), adjusting for sociodemographic and vascular risk factors, and taking into account the ApoE genotype...
  8. pmc Analysis of the effect of aluminum in drinking water and transferrin C2 allele on Alzheimer's disease
    V Rondeau
    INSERM EMI 0338, Universite Victor Segalen Bordeaux, Bordeaux, France
    Eur J Neurol 13:1022-5. 2006
    ..Logistic regression analysis showed that neither Tf C2 nor its interaction with Al or with the epsilon4 allele of the ApoE were significantly associated with the risk of AD...
  9. ncbi request reprint Oral health condition of French elderly and risk of dementia: a longitudinal cohort study
    E Arrive
    Department of Oral Health, Universite Victor Segalen, Bordeaux, France
    Community Dent Oral Epidemiol 40:230-8. 2012
    ..The objective of this study thus was to describe the oral condition of French community-dwelling elderly persons and to assess its relationship with the occurrence of dementia...
  10. ncbi request reprint Mortality with dementia: results from a French prospective community-based cohort
    C Helmer
    INSERM U 330, Universite de Bordeaux II, Bordeaux, France
    Am J Epidemiol 154:642-8. 2001
    ..47, 95% CI: 0.27, 0.83). Educational level was not significantly associated with survival in persons with dementia. These results provide further evidence of the malignancy of dementia, which will be a challenge for the 21st century...
  11. ncbi request reprint Association between antioxidant nutritional indicators and the incidence of dementia: results from the PAQUID prospective cohort study
    C Helmer
    INSERM U 330, Universite de Bordeaux II, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    Eur J Clin Nutr 57:1555-61. 2003
    ..To analyse the relation between antioxidant vitamins A, E, and malondialdehyde (MDA) lipoperoxidation product plasma concentrations with incident dementia...
  12. ncbi request reprint Correlates of regular fish consumption in French elderly community dwellers: data from the Three-City study
    P Barberger-Gateau
    INSERM U593, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Eur J Clin Nutr 59:817-25. 2005
    ..The objective of this study was to describe the characteristics of older fish consumers, in order to identify potential confounders in this relationship...
  13. ncbi request reprint A hierarchical model of domains of disablement in the elderly: a longitudinal approach
    P Barberger-Gateau
    INSERM U330, Universite Victor Segalen Bordeaux 2, France
    Disabil Rehabil 22:308-17. 2000
    ....
  14. doi request reprint Nutrient patterns and risk of fracture in older subjects: results from the Three-City Study
    C Samieri
    Department of Nutritional Epidemiology, INSERM U897, Bordeaux, 33076, France
    Osteoporos Int 24:1295-305. 2013
    ..Patterns associated with higher intakes of Ca, P, vitamin B12, proteins and unsaturated fats, and moderate alcohol intake, provided by diets rich in dairies and charcuteries, were related to a lower risk of wrist and hip fractures...
  15. ncbi request reprint Incidence and mortality of Alzheimer's disease or dementia using an illness-death model
    D Commenges
    INSERM E03 38, ISPED, 146 rue Leo Saignat, Bordeaux, 33076, France
    Stat Med 23:199-210. 2004
    ..The most likely explanation of this result seems to be in a shift in the diagnosis of dementia towards earlier stages of the disease prompted by a change in the perception of dementia and the arrival of new drugs...
  16. ncbi request reprint Benzodiazepine use in an elderly community-dwelling population. Characteristics of users and factors associated with subsequent use
    A Fourrier
    Departement de Pharmacologie Clinique, Universite Victor Segalen Bordeaux 2, France
    Eur J Clin Pharmacol 57:419-25. 2001
    ..The objective of this study was to describe determinants of current and subsequent benzodiazepine use in an elderly population, the Paquid cohort...
  17. ncbi request reprint A penalized likelihood approach for arbitrarily censored and truncated data: application to age-specific incidence of dementia
    P Joly
    INSERM U 330, Universite de Bordeaux II, France
    Biometrics 54:185-94. 1998
    ..We apply this method to the analysis of data from a large cohort study on cerebral aging. The age-specific incidence of dementia is estimated and risk factors of dementia studied...
  18. ncbi request reprint Modelling age-specific risk: application to dementia
    D Commenges
    INSERM U330, Bardeaux, France
    Stat Med 17:1973-88. 1998
    ..The estimated incidences computed separately for men and women cross and it is verified that a non-proportional hazards model for gender holds; women below 75 have a lower risk than men while women above 75 have a higher risk...
  19. ncbi request reprint Dyspnea and 8-year mortality among elderly men and women: the PAQUID cohort study
    J F Tessier
    INSERM U330, ISPED, Universite Bordeaux II, France
    Eur J Epidemiol 17:223-9. 2001
    ..These results show that dyspnea grade 3 or higher is an important predictive symptom of mortality, thus suggesting that this is a threshold defining the dyspneic subject...
  20. ncbi request reprint [Normative data for the MMSE, the Benton visual retention test, the Isaacs's set test, the digit symbol substitution test and the Zazzo's cancellation task in subjects over the age 70: results from the PAQUID Study]
    N Lechevallier-Michel
    Departement de Pharmacologie, EA 3676 Médicaments, Produits et Systèmes de Santé, Universite Victor Segalen Bordeaux 2, Bordeaux
    Rev Neurol (Paris) 160:1059-70. 2004
    ....
  21. pmc Longitudinal analysis of the effect of apolipoprotein E epsilon4 and education on cognitive performance in elderly subjects: the PAQUID study
    M Winnock
    INSERM U330, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    J Neurol Neurosurg Psychiatry 72:794-7. 2002
    ....
  22. ncbi request reprint Neurodegenerative diseases and exposure to pesticides in the elderly
    Isabelle Baldi
    Laboratoire Santé Travail Environnement, Institut de Santé Publique d Epidémiologie et de Développement, Universite Victor Segalen Bordeaux 2, Bordeaux, France
    Am J Epidemiol 157:409-14. 2003
    ..These results suggest the presence of neurologic impairments in elderly persons who were exposed occupationally to pesticides...
  23. ncbi request reprint Plasma eicosapentaenoic acid is inversely associated with severity of depressive symptomatology in the elderly: data from the Bordeaux sample of the Three-City Study
    Catherine Feart
    INSERM U593, Equipe Epidémiologie de la Nutrition et des Comportements Alimentaires, Bordeaux, France
    Am J Clin Nutr 87:1156-62. 2008
    ..Depressive symptoms are commonly observed in elderly people, and nutritional factors such as polyunsaturated fatty acids (PUFAs) have been proposed as potential protective determinants of depressive disorders...
  24. ncbi request reprint Dietary patterns derived by hybrid clustering method in older people: association with cognition, mood, and self-rated health
    Cecilia Samieri
    INSERM, U897, University Victor Segalen Bordeaux 2, Case 11, 146 rue Leo Saignat, F 33076 Bordeaux cedex, France
    J Am Diet Assoc 108:1461-71. 2008
    ..Dietary patterns that represent a combination of foods may better predict disease risk than single foods or nutrients...
  25. doi request reprint Gender and education impact on brain aging: a general cognitive factor approach
    Cécile Proust-Lima
    Biostatistics Department, INSERM U897, Bordeaux Cedex 33076, France
    Psychol Aging 23:608-20. 2008
    ..Subjects with higher education exhibited a better mean score for the 4 tests, but this difference tended to attenuate with age for tests involving a speed component...
  26. ncbi request reprint Effects of exposure of the ear to GSM microwaves: in vivo and in vitro experimental studies
    Jean Marie Aran
    Inserm 99 27 Cellular and Molecular Biology of Hearing, Pellegrin Hospital and University, Victor Segalen Bordeaux 2, Bordeaux, France
    Int J Audiol 43:545-54. 2004
    ..These results provided no evidence that microwave radiation, at the levels produced by mobile phones, caused damage to the inner ear or the auditory pathways in our experimental animals...
  27. ncbi request reprint Influence of education on the pattern of cognitive deterioration in AD patients: the cognitive reserve hypothesis
    Nicolas Le Carret
    INSERM U 593, Universite Victor Segalen, Bordeaux, France
    Brain Cogn 57:120-6. 2005
    ..In this latter case, high-educated patients may still benefit from cognitive reserve after the diagnosis of the dementia...
  28. ncbi request reprint Risk of dementia and alcohol and wine consumption: a review of recent results
    Luc Letenneur
    INSERM U593, Case 11, Universite Victor Segalen Bordeaux 2, 146 rue Leo Saignat 33076 Bordeaux Cedex, France
    Biol Res 37:189-93. 2004
    ..Several studies have been published and the overall conclusion is that heavy drinking is a risk factor for most stroke subtypes. Regular light to moderate drinking seemed to be associated with a decreased risk for ischaemic stroke...
  29. ncbi request reprint Benzodiazepine use and risk of dementia: a nested case-control study
    Rajaa Lagnaoui
    Departement de Pharmacologie, Universite Victor Segalen, Bordeaux 2, 33 076 Bordeaux, France
    J Clin Epidemiol 55:314-8. 2002
    ..0; 95% CI, 0.6-1.6). Our finding suggest that former use of benzodiazepines could be a risk factor for dementia, but more detailed investigation are needed...
  30. ncbi request reprint Low plasma eicosapentaenoic acid and depressive symptomatology are independent predictors of dementia risk
    Cecilia Samieri
    INSERM, U897, Equipe Epidémiologie de Nutrition et des Comportements Alimentaires, Bordeaux, France
    Am J Clin Nutr 88:714-21. 2008
    ..Plasma n-3 PUFAs have been shown to be inversely related to the risk of dementia and to depression, which is frequently associated with dementia...
  31. ncbi request reprint Benzodiazepines and injurious falls in community dwelling elders
    Antoine Pariente
    Institut National de la Santé et la Recherche Médicale INSERM, U657, Bordeaux, France
    Drugs Aging 25:61-70. 2008
    ..Benzodiazepines are frequently used medications in the elderly, in whom they are associated with an increased risk of falling, with sometimes dire consequences...
  32. pmc Fish, meat, and risk of dementia: cohort study
    Pascale Barberger-Gateau
    INSERM U330, Universite Victor Segalen Bordeaux 2, case n degrees 11, 146 rue Leo Saignat, 33076 Bordeaux Cedex, France
    BMJ 325:932-3. 2002
  33. ncbi request reprint Estimated number of women likely to benefit from bone mineral density measurement in France
    Nassira Amamra
    Département d information médicale des Hospices Civils de Lyon, 162 Avenue Lacassagne, 69003 Lyon, France
    Joint Bone Spine 71:409-18. 2004
    ..The study was commissioned by the French health authorities...
  34. ncbi request reprint A latent process model for dementia and psychometric tests
    Julien Ganiayre
    INSERM U875, ISPED, 146 rue Leo Saignat, Bordeaux 33076, France
    Lifetime Data Anal 14:115-33. 2008
    ..The predictive ability of the model is illustrated by predicting diagnosis of dementia at the 8 year follow-up of the PAQUID study based on the information from the first 5 years...
  35. ncbi request reprint Influence of education on the benton visual retention test performance as mediated by a strategic search component
    Nicolas Le Carret
    INSERM U 330, Universite Victor Segalen, Bordeaux, France
    Brain Cogn 53:408-11. 2003
    ..The ability of high educational level subjects to use more efficient strategies may participate to the 'cognitive reserve' capacity...
  36. ncbi request reprint Cognitive slowing and learning of target detection skills in pre-demented subjects
    Helene Amieva
    INSERM U593, Universite de Bordeaux II, Bordeaux, France
    Brain Cogn 54:212-4. 2004
    ..Additionally, the two groups significantly improved their time performances all along the test suggesting that both groups including the pre-demented group were able to progressively acquire a target detection skill...
  37. ncbi request reprint A nonlinear latent class model for joint analysis of multivariate longitudinal data and a binary outcome
    Cécile Proust-Lima
    Institut National de la Sante et de la Recherche Medicale, Equipe de biostatistique E0338, 33076 Bordeaux, France
    Stat Med 26:2229-45. 2007
    ....
  38. ncbi request reprint Dementia in subjects aged 75 years or over within the PAQUID cohort: prevalence and burden by severity
    Catherine Helmer
    INSERM U 593 Université de Bordeaux 2, Bordeaux, France
    Dement Geriatr Cogn Disord 22:87-94. 2006
    ..To analyze the prevalence of dementia by severity and to describe the sociodemographic characteristics of people with dementia in the community, as well as the consequences of this disease in terms of disability and institutionalization...
  39. ncbi request reprint Cube drawing performances in normal ageing and Alzheimer's disease: data from the PAQUID elderly population-based cohort
    Yann Gaestel
    INSERM U 593, University Victor Segalen Bordeaux 2, Bordeaux, France
    Dement Geriatr Cogn Disord 21:22-32. 2006
    ..7% did not benefit from the presentation of the model. Analysis showed that persistent failure in the copy condition was the best level of differentiation between normal and AD subjects...
  40. ncbi request reprint Ten-year change in disability prevalence and related factors in two generations of French elderly community dwellers: data from the PAQUID study
    Karine Pérès
    INSERM U593, Case 11, Universite Victor Segalen Bordeaux 2, 146, rue Leo Saignat, 33076 Bordeaux Cedex, France
    Aging Clin Exp Res 17:229-35. 2005
    ..Our aim was to study the 10-year evolution of disability prevalence in elderly community dwellers and related factors...
  41. ncbi request reprint Annual rate and predictors of conversion to dementia in subjects presenting mild cognitive impairment criteria defined according to a population-based study
    Helene Amieva
    INSERM Unit 593, Universite Victor Segalen, Bordeaux, France
    Dement Geriatr Cogn Disord 18:87-93. 2004
    ..Among the variables considered, the Letter Cancellation Test proved to be a major predictor of short-term conversion to dementia...
  42. ncbi request reprint The 9 year cognitive decline before dementia of the Alzheimer type: a prospective population-based study
    Helene Amieva
    INSERM Institut National de la Santé et de la Recherche Médicale Unit 593, Bordeaux, France
    Brain 128:1093-101. 2005
    ....
  43. ncbi request reprint Energy, macronutrient and fatty acid intake of French elderly community dwellers and association with socio-demographic characteristics: data from the Bordeaux sample of the Three-City Study
    Catherine Feart
    INSERM U593, Universite Bordeaux 2, France
    Br J Nutr 98:1046-57. 2007
    ..9 and decreased with higher educational level. The present results suggest that being female, older age, being widowed and low income level could be considered as risk factors of inadequate dietary intake...