Research Topics
| O LesensSummaryCountry: France Publications
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Publications
Bacteremia and endocarditis caused by a Gordonia species in a patient with a central venous catheterO Lesens
Service des Maladies Infectieuses et Tropicales, Clinique Medicale A, Hopitaux Universitaires, Strasbourg, France
Emerg Infect Dis 6:382-5. 2000..sputi but exhibiting some atypical biochemical features in a 31-year-old woman with a central venous catheter. This unusual pathogen may be a new cause of opportunistic infections in patients with severe underlying diseases...
Healthcare-associated Staphylococcus aureus bacteremia and the risk for methicillin resistance: is the Centers for Disease Control and Prevention definition for community-acquired bacteremia still appropriate?Olivier Lesens
Service des Maladies Infectieuses et Tropicales, Hotel Dieu, Clermont Ferrand, France
Infect Control Hosp Epidemiol 26:204-9. 2005..To evaluate a new classification for bloodstream infections that differentiates hospital acquired, healthcare associated, and community acquired in patients with blood cultures positive for Staphylococcus aureus...
[Vancomycin resistant Enterococci (VRE)]O Lesens
université Clermont 1, CHU de Clermont Ferrand, Clermont Ferrand, France
Nephrol Ther 5:S261-4. 2009..Intestinal colonization precedes infection and is responsible for VRE silent dissemination. In case of epidemy, infection control measures should be quickly implemented to avoid endemicity...- Positive surveillance blood culture is a predictive factor for secondary metastatic infection in patients with Staphylococcus aureus bacteraemiaOlivier Lesens
Service des Maladies Infectieuses et Tropicales, Clinique Medicale A, Hopitaux Universitaires, Fédération des services de médecine interne, Hopital Civil, 1 Place de l Hopital, B P, 426 67091 Strasbourg Cedex, France
J Infect 48:245-52. 2004..This cohort study aimed to assess the prognostic value of sustained bacteraemia for outcomes related to Staphylococcus aureus bacteraemia... - [Severe acute respiratory syndrome (SARS). The questions raised by the management of a patient in Besançon and Strasbourg]O Lesens
Service des Maladies Infectieuses et Tropicales, Clinique Medicale A, Hopitaux Universitaires, Strasbourg
Presse Med 32:1359-64. 2003..In France, 5 probable cases of SARS were diagnosed until May 2003. We report the case of one of the 5 French cases, hospitalized successively in Besançon then in Strasbourg... - [Prognostic value of the LRINEC score (Laboratory Risk Indicator for Necrotizing Fasciitis) in soft tissue infections: a prospective study at Clermont-Ferrand University hospital]V Corbin
Service des Maladies Infectieuses et Tropicales, CHU de Clermont Ferrand, 63000 Clermont Ferrand, France
Ann Dermatol Venereol 137:5-11. 2010..The LRINEC score was developed in a retrospective study in order to distinguish necrotizing fasciitis from severe soft tissue infections using laboratory data... - Successful control of a hospital-wide vancomycin-resistant Enterococcus faecium outbreak in FranceC Aumeran
Université Clermont1, centre hospitalier universitaire de Clermont Ferrand, Clermont Ferrand, France
Eur J Clin Microbiol Infect Dis 27:1061-4. 2008..In conclusion, a hospital-wide VRE outbreak was successfully controlled by a strategy based on routine screening, the reinforcement of hand hygiene and taking barrier precautions... - Culture of per-wound bone specimens: a simplified approach for the medical management of diabetic foot osteomyelitisO Lesens
Service des Maladies Infectieuses et Tropicales, Hopital Gabriel Montpied, CHU, Clermont Ferrand, France
Clin Microbiol Infect 17:285-91. 2011..In conclusion, a simplified procedure based on the culture of bone sample obtained via the ulcer after a careful debridement of the wound is effective in the medical management of diabetic foot osteomyelitis... - [Potential nosocomial disseminated infection due to Nocardia asteroides after a prosthesis insertion in an immunocompetent patient]N Mrozek
Service des Maladies Infectieuses et Tropicales, Hotel Dieu, CHU de Clermont Ferrand, 63000 Clermont Ferrand, France
Rev Med Interne 29:1034-7. 2008..The clinical history is highly suggestive of a hospital-acquired infection... - [Cryptococcal meningitis disclosed by visual loss in HIV negative patient with ventriculo-atrial shunting]X Gibold
Service des Maladies Infectieuses et Tropicales, , CHU, 63000 Clermont-Ferrand, France
Rev Med Interne 27:330-2. 2006..However it remains a very rare complication of sarcoidosis. Because of its potential severity (mortality rate of 40%), the diagnosis of cryptococcosis should be evoked as a differential diagnosis of neuro-sarcoidosis... - Assessment on experimental bacterial biofilms and in clinical practice of the efficacy of sampling solutions for microbiological testing of endoscopesC Aumeran
Service d Hygiène Hospitalière, CHU Clermont Ferrand, Clermont Ferrand, France
J Clin Microbiol 50:938-42. 2012..A sampling solution with a tensioactive action is more efficient than saline in detecting biofilm contamination of endoscopes... - [Invasive Streptococcus agalactiae infections in non-pregnant adults]N Lefebvre
Service des Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire de Strasbourg, 1, Place de l Hopital, 67091 Strasbourg Cedex, France
Med Mal Infect 37:796-801. 2007..We describe these conditions and clinical characteristics of patients followed in our teaching hospital... - [Carcinoma cuniculatum: an uneasy diagnosis to suspect in case of chronic osteomyelitis with unsuccessful outcome despite appropriate antibiotic therapy]V Corbin
Service de Maladies Infectieuses, Hotel Dieu, Clermont Ferrand, France
Rev Med Interne 27:713-6. 2006..The clinical and histological features of cuniculatum carcinoma (CC) are often misleading... - Comparison of microbiological results of needle puncture vs. superficial swab in infected diabetic foot ulcer with osteomyelitisL Kessler
Department of Endocrinology and Diabetology, University Hospital, Strasbourg, France
Diabet Med 23:99-102. 2006..To study prospectively two methods for the bacteriological diagnosis of osteomyelitis related to diabetic foot ulcer: needle puncture performed across normal skin surrounding the foot ulcer and superficial swabbing of the ulcer... - [Vancomycin-resistant Enterococcus in an epidemic situation: screening at admission for patients at risk of carriage]Olivier Lesens
Service des Maladies Infectieuses et Tropicales, CHU de Clermont Ferrand, France
Presse Med 35:1167-73. 2006..To evaluate a strategy based on screening and isolation at admission to a department of infectious diseases during an epidemic of vancomycin-resistant Enterococcus (VRE) at the University Hospital of Clermont-Ferrand... - [Cogan's syndrome revealed by haemorrhagic glairous diarrhoea]A C Bursztejn
Service des Maladies Infectieuses et Tropicales, Clinique Medicale A, Hopitaux Universitaires, Fédération des services de médecine interne, Hopital, BP 426, 67091 Strasbourg Cedex, France
Presse Med 34:289-92. 2005..Cogan's syndrome is defined by the combination of non syphilitic interstitial keratitis and inner ear dysfunction, similar to Meniere's disease... - A case of Aspergillus mediastinitis after heart transplantation successfully treated with liposomal amphotericin B, caspofungin and voriconazoleE Forestier
Infectious Diseases Department, Hopitaux Universitaires de Strasbourg, 1 Place de l Hopital, 67094 Strasbourg Cedex, France
Eur J Clin Microbiol Infect Dis 24:347-9. 2005..In the few existing reports, evolution was generally fatal, especially in immunocompromised patients, despite treatment with antifungal drugs and surgery... - Role of comorbidity in mortality related to Staphylococcus aureus bacteremia: a prospective study using the Charlson weighted index of comorbidityOlivier Lesens
Service des Maladies Infectieuses et Tropicales, , , Strasbourg, France
Infect Control Hosp Epidemiol 24:890-6. 2003..The Charlson WIC is a good predictor of mortality in this population and may be a useful instrument to control comorbidity in studies aiming to investigate risk factors for death due to bacteremia... - Methicillin-susceptible, doxycycline-resistant Staphylococcus aureus, Côte d'IvoireOlivier Lesens
Maladies Infectieuses et Tropicales, Centre Hospitalier Universitaire, Clermont Ferrand, France
Emerg Infect Dis 13:488-90. 2007..In a transssectional survey, nasal carriage of this strain was found in 2.9% of 273 soldiers about to be sent to Côte d'Ivoire and was associated with prior malaria prophylaxis with doxycycline... - [Non Hodgkin's and Hodgkin's lymphomas and HIV: frequency, outcome and immune response under HAART; Clermont-Ferrand University Hospital, 1991-2003]C Jacomet
Service des Maladies Infectieuses et Tropicales, CHU de Clermont Ferrand, BP 69, 63000 Clermont Ferrand, France
Med Mal Infect 36:157-62. 2006.... - [Emergence of monomicrobial methicillin-resistant Staphylococcus aureus infections in diabetic foot osteomyelitis (retrospective study of 48 cases)]Gaëlle Couret
Service des Maladies Infectieuses et Tropicales, Hotel Dieu, CHU, Clermont Ferrand 63 Service d endocrinologie, Hopital Gabriel Montpied, CHU, Clermont Ferrand 63
Presse Med 36:851-8. 2007..Describe the clinical appearance, microorganisms involved, and prognosis of diabetic foot osteomyelitis... - [Should presumptive meningoencephalitis treatment in adults be active against Mycoplasma pneumoniae?]S Trouillier
Service des Maladies Infectieuses et Tropicales, Hotel Dieu, CHU, Boulevard Leon Malfreyt, 63000 Clermont Ferrand, France
Med Mal Infect 37:738-45. 2007..Meningoencephalitis is the most common central nervous system complication caused by Mycoplasma pneumoniae. Its frequency is probably underestimated... - Probiotics and intestinal colonization by vancomycin-resistant enterococci in mice and humansMagali Vidal
Service des Maladies Infectieuses et Tropicales, CHU Clermont Ferrand, Clermont Ferrand, France
J Clin Microbiol 48:2595-8. 2010..No effect of Lcr35 was observed in a double-blind placebo randomized study, involving nine patients... - [Prevention and infection in adults patients with hyposplenism]V Chanet
Service de Maladies Infectieuses, Hotel Dieu, Boulevard Leon Malfreyt, 63000 Clermont Ferrand, France
Med Mal Infect 34:493-8. 2004..Despite these prevention policies, the patient must be informed of the risk of very severe infection... - Outbreak of colonization and infection with vancomycin-resistant Enterococcus faecium in a French university hospitalOlivier Lesens
Service des Maladies Infectieuses et Tropicales, Clermont Ferrand, France
Infect Control Hosp Epidemiol 27:984-6. 2006..002), and prior exposure to antianaerobials (OR, 11 [95% CI, 1.5-88]; P<.02) were independently predictive of vancomycin-resistant Enterococcus faecium carriage... - Introduction of SARS in France, March-April, 2003Jean Claude Desenclos
Département Maladies Infectieuses, Institut de Veille Sanitaire, Saint Maurice, France
Emerg Infect Dis 10:195-200. 2004..Timely detection, isolation of probable case-patients, and quarantine of their contacts appear to have been effective in preventing the secondary spread of SARS in France... - Evolution of TEM-type enzymes: biochemical and genetic characterization of two new complex mutant TEM enzymes, TEM-151 and TEM-152, from a single patientFrederic Robin
CHU Clermont Ferrand, Centre de Biologie, Laboratoire de Bactériologie Clinique, Clermont Ferrand F 63003, France
Antimicrob Agents Chemother 51:1304-9. 2007..17 microM). These results confirm the evolution of TEM-type enzymes toward complex enzymes harboring the two kinds of substitutions which confer an extended spectrum of action against beta-lactam antibiotics and resistance to inhibitors... - Evaluation of a new chromogenic medium, ChromID VRE, for detection of vancomycin-resistant Enterococci in stool samples and rectal swabsJulien Delmas
Laboratoire de Bactériologie Clinique, Centre de Biologie, CHU Clermont Ferrand, Clermont Ferrand F 63003, France
J Clin Microbiol 45:2731-3. 2007..ChromID VRE in combination with Gram straining provided a higher specificity than Enterococcosel, irrespective of the incubation time and enrichment...