Caroline Leroux

Summary

Country: France

Publications

  1. ncbi request reprint Transient immune suppression of inapparent carriers infected with a principal neutralizing domain-deficient equine infectious anaemia virus induces neutralizing antibodies and lowers steady-state virus replication
    Jodi K Craigo
    Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Gen Virol 83:1353-9. 2002
  2. ncbi request reprint Jaagsiekte Sheep Retrovirus (JSRV): from virus to lung cancer in sheep
    Caroline Leroux
    Universite de Lyon 1, INRA, UMR754, Ecole Nationale Veterinaire de Lyon, IFR 128, F 69007, Lyon, France
    Vet Res 38:211-28. 2007
  3. pmc Lung progenitors from lambs can differentiate into specialized alveolar or bronchiolar epithelial cells
    Fabienne Archer
    Universite de Lyon, Lyon F 69007, France
    BMC Vet Res 9:224. 2013
  4. pmc Interstitial lung disease associated with Equine Infectious Anemia Virus infection in horses
    Pompei Bolfa
    UMR754, Retrovirus and Comparative Pathology, INRA, Lyon, France
    Vet Res 44:113. 2013
  5. pmc In silico segmentations of lentivirus envelope sequences
    Aurélia Boissin-Quillon
    UMR754 INRA ENVL UCBL Rétrovirus et Pathologie Comparée, IFR 128 Biosciences Lyon Gerland, Universite Claude Bernard Lyon 1, Lyon, France
    BMC Bioinformatics 8:99. 2007
  6. ncbi request reprint Equine Infectious Anemia Virus (EIAV): what has HIV's country cousin got to tell us?
    Caroline Leroux
    UMR754 INRA UCBL ENVL Rétrovirus et Pathologie Comparée, IFR128, Universite Claude Bernard Lyon I, 50 avenue Tony Garnier, 69007 Lyon, France
    Vet Res 35:485-512. 2004
  7. ncbi request reprint SRLVs: a genetic continuum of lentiviral species in sheep and goats with cumulative evidence of cross species transmission
    Caroline Leroux
    Universite de Lyon, Lyon, France
    Curr HIV Res 8:94-100. 2010
  8. pmc Professional exposure to goats increases the risk of pneumonic-type lung adenocarcinoma: results of the IFCT-0504-Epidemio study
    Delphine Lutringer-Magnin
    Hospices Civils de Lyon, Lyon, France
    PLoS ONE 7:e37889. 2012
  9. doi request reprint Small ruminant lentivirus proviral sequences from wild ibexes in contact with domestic goats
    Esadk Erhouma
    Universite de Lyon, F 69007 Lyon, France
    J Gen Virol 89:1478-84. 2008
  10. pmc Copy number variation and differential expression of a protective endogenous retrovirus in sheep
    Barbara Viginier
    UMR754 Rétrovirus et Pathologie Comparée INRA, Universite Lyon 1, Universite de Lyon, Lyon, France
    PLoS ONE 7:e41965. 2012

Collaborators

  • Massimo Palmarini
  • Nicolas Girard
  • Yahia Chebloune
  • Elisabeth Quoix
  • Luc Chabanne
  • J F Mornex
  • V Cottin
  • Philippe Vanhems
  • Catherine Bonnefont-Rebeix
  • Fabienne Archer
  • Christine Dolmazon
  • Jodi K Craigo
  • Ronald C Montelaro
  • Charles J Issel
  • Pompei Bolfa
  • Delphine Lutringer-Magnin
  • Barbara Viginier
  • Sheila J Cook
  • François Guiguen
  • Laryssa Howe
  • Esadk Erhouma
  • Mariana Varela
  • Aurélia Boissin-Quillon
  • Monique Lyon
  • Bruno Salaun
  • Jonathan Carlson
  • R Frank Cook
  • Cornel Catoi
  • Barbara Gineys
  • Marie Nolf
  • Sophie Desloire
  • Alain Abi-Rizk
  • Jean Luc Cadoré
  • Geneviève Cordier
  • Jacques Cadranel
  • Christophe Terzian
  • Corinne Del Signore
  • Isabelle Lantier
  • Frederic Lantier
  • Marie Paule Lebitasy
  • Matthew Golder
  • Marcelo de las Heras
  • Laila Mselli Lakhal
  • Dominique Gauthier
  • Timothy Greenland
  • Théodore Alogninouwa
  • Joelle Chastang
  • Emilie Jacquier
  • Didier Piau
  • Timothy J Sturgeon
  • Jean Davoust
  • Monique Kleijmeer
  • Sylvie Isaac
  • Yves Pacheco
  • Jean Jacques Pin
  • Valérie Clair-Moninot
  • Isabelle Treilleux
  • Sophie Goddard
  • Serge Lebecque
  • Janice Griffith
  • Blandine de Saint-Vis
  • Arnaud Riesler
  • Nathalie Pacheco
  • Pamela S Bolin
  • Michelle R Mousel
  • Anne Vaiman
  • Dennis Knudson
  • James DeMartini
  • Nadia N Ghabrial
  • Marie Gantz
  • Jeanette Bishop
  • Edmond Cribiu
  • Sandra L Berger
  • Susan Brown
  • Jonathan D Steckbeck

Detail Information

Publications18

  1. ncbi request reprint Transient immune suppression of inapparent carriers infected with a principal neutralizing domain-deficient equine infectious anaemia virus induces neutralizing antibodies and lowers steady-state virus replication
    Jodi K Craigo
    Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    J Gen Virol 83:1353-9. 2002
    ....
  2. ncbi request reprint Jaagsiekte Sheep Retrovirus (JSRV): from virus to lung cancer in sheep
    Caroline Leroux
    Universite de Lyon 1, INRA, UMR754, Ecole Nationale Veterinaire de Lyon, IFR 128, F 69007, Lyon, France
    Vet Res 38:211-28. 2007
    ..Activation of the PI3K/Akt and MAPK pathways participates in the envelope-induced transformation. Tumour development is associated with telomerase activation. This review will focus on the induction of cancer by JSRV...
  3. pmc Lung progenitors from lambs can differentiate into specialized alveolar or bronchiolar epithelial cells
    Fabienne Archer
    Universite de Lyon, Lyon F 69007, France
    BMC Vet Res 9:224. 2013
    ..In this study, we aimed to establish the presence of bronchioloalveolar progenitors in ovine lungs and to characterize their potential to differentiate into specialized cells...
  4. pmc Interstitial lung disease associated with Equine Infectious Anemia Virus infection in horses
    Pompei Bolfa
    UMR754, Retrovirus and Comparative Pathology, INRA, Lyon, France
    Vet Res 44:113. 2013
    ..The presence of EIAV capsid in lung epithelial cells suggests that EIAV might be responsible for the broncho-interstitial damages observed...
  5. pmc In silico segmentations of lentivirus envelope sequences
    Aurélia Boissin-Quillon
    UMR754 INRA ENVL UCBL Rétrovirus et Pathologie Comparée, IFR 128 Biosciences Lyon Gerland, Universite Claude Bernard Lyon 1, Lyon, France
    BMC Bioinformatics 8:99. 2007
    ..We look for specific signatures of C/V regions, using hidden Markov models constructed with SU sequences of the equine, human, small ruminant and simian lentiviruses...
  6. ncbi request reprint Equine Infectious Anemia Virus (EIAV): what has HIV's country cousin got to tell us?
    Caroline Leroux
    UMR754 INRA UCBL ENVL Rétrovirus et Pathologie Comparée, IFR128, Universite Claude Bernard Lyon I, 50 avenue Tony Garnier, 69007 Lyon, France
    Vet Res 35:485-512. 2004
    ..These studies are of interest in the context of HIV and efforts to develop a vaccine. This review will focus on some of the most recent results...
  7. ncbi request reprint SRLVs: a genetic continuum of lentiviral species in sheep and goats with cumulative evidence of cross species transmission
    Caroline Leroux
    Universite de Lyon, Lyon, France
    Curr HIV Res 8:94-100. 2010
    ..Three classifications have been successively proposed and allowed to refine the SRLV phylogeny over time. Phylogenetic reconstructions support the existence of SRLV cross-species transmission in domestic and wild small ruminants...
  8. pmc Professional exposure to goats increases the risk of pneumonic-type lung adenocarcinoma: results of the IFCT-0504-Epidemio study
    Delphine Lutringer-Magnin
    Hospices Civils de Lyon, Lyon, France
    PLoS ONE 7:e37889. 2012
    ..043), as compared to other subtypes of lung cancer. This case-control suggests a link between professional exposure to goats and P-ADC, and prompts for further epidemiological evaluation of potential environmental risk factors for P-ADC...
  9. doi request reprint Small ruminant lentivirus proviral sequences from wild ibexes in contact with domestic goats
    Esadk Erhouma
    Universite de Lyon, F 69007 Lyon, France
    J Gen Virol 89:1478-84. 2008
    ..One SRLV-positive ibex from a distant site shared similarities with the other ibexes studied in both its gag and LTR sequences, suggesting that a distinct SRLV population could circulate in some wild ibex populations...
  10. pmc Copy number variation and differential expression of a protective endogenous retrovirus in sheep
    Barbara Viginier
    UMR754 Rétrovirus et Pathologie Comparée INRA, Universite Lyon 1, Universite de Lyon, Lyon, France
    PLoS ONE 7:e41965. 2012
    ..We have shown that the W21/R21 ratio is variable within and between breeds. We also describe for the first time that putative protecting enJSRV variants were expressed in alveolar type II cells (AECII), the major target of exJSRV...
  11. ncbi request reprint Alveolar type II cells isolated from pulmonary adenocarcinoma: a model for JSRV expression in vitro
    Fabienne Archer
    Universite de Lyon, INRA, UMR754, and Department of Respiratory Diseases, Reference Center for Orphan Lung Diseases, Louis Pradel Hospital, Hospices Civils de Lyon, France
    Am J Respir Cell Mol Biol 36:534-40. 2007
    ..This novel experimental model will set up the stage for elucidating lung epithelial transformation in the JSRV-induced tumor...
  12. ncbi request reprint Toll-like receptor 3 (TLR3): a new marker of canine monocytes-derived dendritic cells (cMo-DC)
    Catherine Bonnefont-Rebeix
    Immunology Department, Etablissement Français du Sang de Lyon, 1 3 rue du Vercors, 69007 Lyon, France
    Vet Immunol Immunopathol 118:134-9. 2007
    ..In conclusion, this first approach to study canine TLR3 protein expression shows that three anti-TLR3 clones detect canine TLR3 and can be used to better characterize canine DC and the immune system of dogs...
  13. pmc Equine infectious anemia virus envelope evolution in vivo during persistent infection progressively increases resistance to in vitro serum antibody neutralization as a dominant phenotype
    Laryssa Howe
    Department of Infectious Disease and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    J Virol 76:10588-97. 2002
    ....
  14. ncbi request reprint Enhancement of equine infectious anemia virus virulence by identification and removal of suboptimal nucleotides
    R Frank Cook
    Department of Veterinary Science, Gluck Equine Research Center, University of Kentucky, Lexington, KY 40546, USA
    Virology 313:588-603. 2003
    ..013) disease potential in Equus caballus to EIAV(PV). The 68-bp duplication and/or R(103) may limit peak viral RNA accumulation during acute infection...
  15. ncbi request reprint Apparent elimination of EIAV ancestral species in a long-term inapparent carrier
    Jodi K Craigo
    Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA
    Virology 344:340-53. 2006
    ....
  16. pmc A large animal model to evaluate the effects of Hsp90 inhibitors for the treatment of lung adenocarcinoma
    Mariana Varela
    Institute of Comparative Medicine, University of Glasgow Veterinary School, 464 Bearsden Road, Glasgow, G61 1QH, Scotland, UK
    Virology 371:206-15. 2008
    ..Thus, OPA could be used as a large animal model for comprehensive studies investigating the effects of Hsp90 inhibitors in lung adenocarcinoma...
  17. pmc Chromosomal distribution of endogenous Jaagsiekte sheep retrovirus proviral sequences in the sheep genome
    Jonathan Carlson
    Department of Microbiology, Bioagricultural Sciences and Pest Management, Colorado State University, Fort Collins, Colorado 80523, USA
    J Virol 77:9662-8. 2003
    ..The origin and functional significance of these arrays is not known...
  18. pmc CD208/dendritic cell-lysosomal associated membrane protein is a marker of normal and transformed type II pneumocytes
    Bruno Salaun
    Laboratory for Immunological Research, Schering Plough Research Institute, Dardilly, France
    Am J Pathol 164:861-71. 2004
    ..Furthermore, DC-LAMP appears to be a marker of transformed type II pneumocytes as well, an observation that may help the study and the classification of human lung adenocarcinomas...