Bruno Ndjakou Lenta

Summary

Country: France

Publications

  1. request reprint
    Ndjakou Lenta B, Devkota K, Ngouela S, Fekam Boyom F, Naz Q, Choudhary M, et al. Anti-plasmodial and cholinesterase inhibiting activities of some constituents of Psorospermum glaberrimum. Chem Pharm Bull (Tokyo). 2008;56:222-6 pubmed
    ..All tested compounds showed good butyrylcholinesterase inhibition activities with compound 12 displaying the best potency (IC(50) 9.25+/-0.25 microM). All the tested compounds showed weak inhibitory activity against acetylcholinesterase...
  2. Yamthe L, Fokou P, Mbouna C, Keumoe R, Ndjakou B, Djouonzo P, et al. Extracts from Annona Muricata L. and Annona Reticulata L. (Annonaceae) Potently and Selectively Inhibit Plasmodium Falciparum. Medicines (Basel). 2015;2:55-66 pubmed publisher
    ..muricata and A. reticulata in the treatment of malaria. Given their limited cytotoxicity profile, their extracts qualify as promising starting points for antimalarial drug discovery. ..
  3. Tchuente Tchuenmogne M, Kammalac T, Gohlke S, Kouipou R, Aslan A, Kuzu M, et al. Compounds from Terminalia mantaly L. (Combretaceae) Stem Bark Exhibit Potent Inhibition against Some Pathogenic Yeasts and Enzymes of Metabolic Significance. Medicines (Basel). 2017;4: pubmed publisher
    ..b>Conclusions: The results achieved indicate that further SAR studies will likely identify potent hit derivatives that should subsequently enter the drug development pipeline. ..

Detail Information

Publications3

  1. request reprint
    Ndjakou Lenta B, Devkota K, Ngouela S, Fekam Boyom F, Naz Q, Choudhary M, et al. Anti-plasmodial and cholinesterase inhibiting activities of some constituents of Psorospermum glaberrimum. Chem Pharm Bull (Tokyo). 2008;56:222-6 pubmed
    ..All tested compounds showed good butyrylcholinesterase inhibition activities with compound 12 displaying the best potency (IC(50) 9.25+/-0.25 microM). All the tested compounds showed weak inhibitory activity against acetylcholinesterase...
  2. Yamthe L, Fokou P, Mbouna C, Keumoe R, Ndjakou B, Djouonzo P, et al. Extracts from Annona Muricata L. and Annona Reticulata L. (Annonaceae) Potently and Selectively Inhibit Plasmodium Falciparum. Medicines (Basel). 2015;2:55-66 pubmed publisher
    ..muricata and A. reticulata in the treatment of malaria. Given their limited cytotoxicity profile, their extracts qualify as promising starting points for antimalarial drug discovery. ..
  3. Tchuente Tchuenmogne M, Kammalac T, Gohlke S, Kouipou R, Aslan A, Kuzu M, et al. Compounds from Terminalia mantaly L. (Combretaceae) Stem Bark Exhibit Potent Inhibition against Some Pathogenic Yeasts and Enzymes of Metabolic Significance. Medicines (Basel). 2017;4: pubmed publisher
    ..b>Conclusions: The results achieved indicate that further SAR studies will likely identify potent hit derivatives that should subsequently enter the drug development pipeline. ..