Thomas Lenormand

..This finding provides strong empirical support in favour of a population genetic explanation for the evolution of heterochiasmy and, more broadly, for the evolution of sex and recombination...

..We show that stochasticity, by directly steering evolution, has become an essential ingredient of evolutionary theory beyond the classical Wright-Fisher or neutralist-selectionist debates...

..Instead, resistance evolution has been an erratic combination of mutation, positive selection, and the rearrangement of existing variation leading to complex genetic architecture...

..Furthermore, we show that these conditions vary depending on whether these traits are under male or female control, which allows us to describe a new type of male/female conflict...

..This model may offer a simple and widely applicable alternative to complex metabolic network models, in particular for making evolutionary predictions...

..High-resolution analysis of phenotypes distribution thus proved useful for detecting hybrid zone movement even without temporal data...

..We show by simulations that these conclusions are fairly robust to a lower adaptation of the wild type and discuss the relevance of our findings in the context of adaptation theories and experimental evolution...

..However, the survival function was not symmetric, indicating that body mass might not be under stabilizing selection as suggested previously...

..Because dominance is a central parameter for evolutionary theory, and because these predictions are quantitative, they set the stage for a wide range of applications and further empirical tests...

..In particular, the range of parameters most favorable to the maintenance of polymorphism corresponds to situations favoring less assortment...

..This effect is due to the fact that selfing generates a correlation in homozygosity at linked loci, which is reduced by recombination...

..The rate of duplication of ace-1 in C. pipiens is probably underestimated, but seems to be rather high...

..They also suggest that mutation parameter estimates may be strongly biased when measured in stressful environments...

..This mechanism provides a generic yet neglected process for the maintenance of polymorphism or species coexistence...

..Hence, this study suggests that parasites can play a prominent role in host grouping behaviours...

..This study is the first direct demonstration that the process of male-female coevolution, previously revealed by experimental evolution in laboratory artificial conditions, can occur in nature on a short evolutionary time scale...

..More generally, the model seems to qualitatively capture and possibly explain the variation of f(s) from lower to higher organisms, which opens a large array of potential applications in evolutionary genetics...

..We discuss optimal treatment strategies that limit disease prevalence and the evolution of drug-resistance...

..Overall, the framework we propose will help in exploring the full potential of mark-recapture data to study natural selection...

..Overall, our results show that the stochastic theories of the evolution of sex apply to a much broader range of conditions than previously expected...

..Intriguingly, these results may also explain why imprinted regions on the autosomes of humans or sheep are particularly heterochiasmate...

..Nevertheless, neglecting mutational load may to some extent obscure the estimations of selective parameters based either on artificial F1 crosses or on cline characteristics...

..This result, qualitatively different from results obtained with other models of migration evolution, indicates that ignoring drift or the detail of the genetic architecture may lead to incorrect conclusions...

..New studies indicate that this discrepancy might result from the fact that previous models have ignored important complexities that face natural populations, such as genetic drift and the spatial structure of populations...