Gaelle Lelandais

Summary

Country: France

Publications

  1. doi request reprint ChIPseq in Yeast Species: From Chromatin Immunoprecipitation to High-Throughput Sequencing and Bioinformatics Data Analyses
    Gaelle Lelandais
    Institut Jacques Monod, CNRS UMR 7592, University of Paris Diderot, Paris, France
    Methods Mol Biol 1361:185-202. 2016
  2. pmc RNA sequencing revealed novel actors of the acquisition of drug resistance in Candida albicans
    Sanjiveeni Dhamgaye
    Membrane Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India
    BMC Genomics 13:396. 2012
  3. pmc Statistical inference of the time-varying structure of gene-regulation networks
    Sophie Lebre
    Center for Bioinformatics, Imperial College London, London, UK
    BMC Syst Biol 4:130. 2010
  4. pmc Comparative transcriptomics of drought responses in Populus: a meta-analysis of genome-wide expression profiling in mature leaves and root apices across two genotypes
    David Cohen
    INRA, Nancy Universite, UMR1137 Ecologie et Ecophysiologie Forestières, IFR 110 EFABA, F 54280 Champenoux, France
    BMC Genomics 11:630. 2010
  5. doi request reprint The evolution of gene expression regulatory networks in yeasts
    Gaelle Lelandais
    INSERM UMR S 665, Dynamique des Structures et Interactions des Macromolécules Biologiques, Universite Paris Diderot, Sorbonne Paris Cité, INTS, 6 rue Alexandre Cabanel, 75015 Paris, France
    C R Biol 334:655-61. 2011
  6. pmc Genome adaptation to chemical stress: clues from comparative transcriptomics in Saccharomyces cerevisiae and Candida glabrata
    Gaelle Lelandais
    Equipe de Bioinformatique Genomique et Moleculaire, INSERM UMR S726, Universite Paris 7, INTS, 6 rue Alexandre Cabanel, 75015 Paris, France
    Genome Biol 9:R164. 2008
  7. pmc Spatio-temporal dynamics of yeast mitochondrial biogenesis: transcriptional and post-transcriptional mRNA oscillatory modules
    Gaelle Lelandais
    Dynamique des Structures et Interactions des Macromolecules Biologiques DSIMB, INSERM UMR S 665, Universite Paris Diderot, Paris, France
    PLoS Comput Biol 5:e1000409. 2009
  8. pmc yMGV: a cross-species expression data mining tool
    Gaelle Lelandais
    Laboratoire de Genetique Moleculaire, CNRS UMR8541, Ecole Normale Superieure, Paris, France
    Nucleic Acids Res 32:D323-5. 2004
  9. ncbi request reprint The central role of PDR1 in the foundation of yeast drug resistance
    Vivienne Fardeau
    Laboratoire de Genetique Moleculaire, CNRS UMR8541, Paris, France
    J Biol Chem 282:5063-74. 2007
  10. pmc The reconstruction of condition-specific transcriptional modules provides new insights in the evolution of yeast AP-1 proteins
    Christel Goudot
    Dynamique des Structures et Interactions des Macromolécules Biologiques, INSERM, U665 Paris, France
    PLoS ONE 6:e20924. 2011

Collaborators

Detail Information

Publications19

  1. doi request reprint ChIPseq in Yeast Species: From Chromatin Immunoprecipitation to High-Throughput Sequencing and Bioinformatics Data Analyses
    Gaelle Lelandais
    Institut Jacques Monod, CNRS UMR 7592, University of Paris Diderot, Paris, France
    Methods Mol Biol 1361:185-202. 2016
    ..We present here a general protocol to perform ChIPseq analyses in yeast species. This protocol has been optimized to identify target genes of specific transcription factors but can be used for any other DNA binding proteins...
  2. pmc RNA sequencing revealed novel actors of the acquisition of drug resistance in Candida albicans
    Sanjiveeni Dhamgaye
    Membrane Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067, India
    BMC Genomics 13:396. 2012
    ..We used RNA sequencing (RNA-seq) to analyze the transcriptomes of a CDR (Candida Drug Resistance) strain and its isogenic drug sensitive counterpart...
  3. pmc Statistical inference of the time-varying structure of gene-regulation networks
    Sophie Lebre
    Center for Bioinformatics, Imperial College London, London, UK
    BMC Syst Biol 4:130. 2010
    ....
  4. pmc Comparative transcriptomics of drought responses in Populus: a meta-analysis of genome-wide expression profiling in mature leaves and root apices across two genotypes
    David Cohen
    INRA, Nancy Universite, UMR1137 Ecologie et Ecophysiologie Forestières, IFR 110 EFABA, F 54280 Champenoux, France
    BMC Genomics 11:630. 2010
    ..Drought-induced responses were analysed in leaves and root apices and were compared with available transcriptome data from other Populus species...
  5. doi request reprint The evolution of gene expression regulatory networks in yeasts
    Gaelle Lelandais
    INSERM UMR S 665, Dynamique des Structures et Interactions des Macromolécules Biologiques, Universite Paris Diderot, Sorbonne Paris Cité, INTS, 6 rue Alexandre Cabanel, 75015 Paris, France
    C R Biol 334:655-61. 2011
    ..This article reviews some of the main advances made in this field, using yeast species, and especially the species sequenced in the frame of the Genolevures program, as a model...
  6. pmc Genome adaptation to chemical stress: clues from comparative transcriptomics in Saccharomyces cerevisiae and Candida glabrata
    Gaelle Lelandais
    Equipe de Bioinformatique Genomique et Moleculaire, INSERM UMR S726, Universite Paris 7, INTS, 6 rue Alexandre Cabanel, 75015 Paris, France
    Genome Biol 9:R164. 2008
    ....
  7. pmc Spatio-temporal dynamics of yeast mitochondrial biogenesis: transcriptional and post-transcriptional mRNA oscillatory modules
    Gaelle Lelandais
    Dynamique des Structures et Interactions des Macromolecules Biologiques DSIMB, INSERM UMR S 665, Universite Paris Diderot, Paris, France
    PLoS Comput Biol 5:e1000409. 2009
    ..More generally, these observations underscore the importance of post-transcriptional processes in mitochondrial biogenesis, highlighting close connections between nuclear transcription and cytoplasmic site-specific translation...
  8. pmc yMGV: a cross-species expression data mining tool
    Gaelle Lelandais
    Laboratoire de Genetique Moleculaire, CNRS UMR8541, Ecole Normale Superieure, Paris, France
    Nucleic Acids Res 32:D323-5. 2004
    ..This should enable the fission yeast community to take advantage of the large amount of available information on budding yeast transcriptome. New tools and ongoing developments are also presented here...
  9. ncbi request reprint The central role of PDR1 in the foundation of yeast drug resistance
    Vivienne Fardeau
    Laboratoire de Genetique Moleculaire, CNRS UMR8541, Paris, France
    J Biol Chem 282:5063-74. 2007
    ..Thus, Pdr1p is a promoter-resident regulator involved in both basal expression and rapid drug-dependent induction of PDR genes...
  10. pmc The reconstruction of condition-specific transcriptional modules provides new insights in the evolution of yeast AP-1 proteins
    Christel Goudot
    Dynamique des Structures et Interactions des Macromolécules Biologiques, INSERM, U665 Paris, France
    PLoS ONE 6:e20924. 2011
    ....
  11. pmc MiCoViTo: a tool for gene-centric comparison and visualization of yeast transcriptome states
    Gaelle Lelandais
    Laboratoire de Génétique Moléculaire CNRS UMR8541, Ecole Normale Superieure, Paris, 75230 Cedex 05, France
    BMC Bioinformatics 5:20. 2004
    ..One of the challenging questions raised by the tremendous amount of microarray data is to identify groups of co-regulated genes and to understand their role in cell functions...
  12. pmc Comparative analysis of missing value imputation methods to improve clustering and interpretation of microarray experiments
    Magalie Celton
    INSERM UMR S 726, Equipe de Bioinformatique Genomique et Moleculaire, DSIMB, Universite Paris Diderot Paris 7, 2 place Jussieu, Paris, France
    BMC Genomics 11:15. 2010
    ..In this study, we have evaluated twelve different usable methods, and their influence on the quality of gene clustering. Interestingly we have used several datasets, both kinetic and non kinetic experiments from yeast and human...
  13. pmc MitoGenesisDB: an expression data mining tool to explore spatio-temporal dynamics of mitochondrial biogenesis
    Jean Christophe Gelly
    Dynamique des Structures et Interactions des Macromolécules Biologiques, INSERM, U665, Paris F 75015, France
    Nucleic Acids Res 39:D1079-84. 2011
    ..The case of respiratory chain assembly factors illustrates this point. The MitoGenesisDB interface is available at http://www.dsimb.inserm.fr/dsimb_tools/mitgene/...
  14. doi request reprint Posttranscriptional control of mitochondrial biogenesis: spatio-temporal regulation of the protein import process
    Frederic Devaux
    Laboratoire de Génomique des Microorganismes, FRE3214 CNRS, Universite Pierre et Marie Curie, Paris, France
    FEBS Lett 584:4273-9. 2010
    ..A connection with the target of rapamycine signalling pathway may explain how respiratory chain assembly senses environmental conditions via the protein import machinery...
  15. doi request reprint Comparative functional genomics of stress responses in yeasts
    Gaelle Lelandais
    Dynamique des Structures et Interactions des Macromolécules Biologiques, INSERM UMR S 665, Universite Paris Diderot, Paris, France
    OMICS 14:501-15. 2010
    ....
  16. doi request reprint bPeaks: a bioinformatics tool to detect transcription factor binding sites from ChIPseq data in yeasts and other organisms with small genomes
    Jawad Merhej
    Sorbonne Universités, UPMC University of Paris 06, UMR 7238, Laboratoire de Biologie Computationnelle et Quantitative, Paris, France CNRS, UMR 7238, Laboratoire de Biologie Computationnelle et Quantitative, Paris, France
    Yeast 31:375-91. 2014
    ..The bioinformatics tool bPeaks is freely distributed to academic users. Supplementary data, together with detailed tutorials, are available online: http://bpeaks.gene-networks.net...
  17. doi request reprint Yap7 is a transcriptional repressor of nitric oxide oxidase in yeasts, which arose from neofunctionalization after whole genome duplication
    Jawad Merhej
    Sorbonne Universités, UPMC Univ Paris 06, Institut de Biologie Paris Seine UMR 7238, Laboratoire de Biologie Computationnelle et Quantitative, F 75006, Paris, France
    Mol Microbiol 96:951-72. 2015
    ..glabrata and S. cerevisiae extant species. This work describes a new aspect of the regulation of fungal nitric oxidase and provides detailed insights into its functioning and evolution...
  18. pmc Global stress response in a prokaryotic model of DJ-1-associated Parkinsonism
    Nadia Messaoudi
    Stress Molecules, Institut Jacques Monod, Universite Paris, Paris, France
    J Bacteriol 195:1167-78. 2013
    ..Thus, protein defects resulting from the yajL mutation trigger the onset of a robust and global stress response in a prokaryotic model of DJ-1-associated Parkinsonism...
  19. pmc The metacaspase (Mca1p) has a dual role in farnesol-induced apoptosis in Candida albicans
    Thibaut Léger
    From the Mass spectrometry Laboratory, Institut Jacques Monod, UMR 7592, Univ Paris Diderot, CNRS, Sorbonne Paris Cité, F 75205 Paris, France
    Mol Cell Proteomics 14:93-108. 2015
    ..Finally, Mca1p appears to contribute significantly to the control of mitochondria biogenesis and degradation. Consequently, Mca1p may be a link between the extrinsic and the intrinsic programmed cell death pathways in C. albicans. ..