Jean Marie Lehn

Summary

Country: France

Publications

  1. ncbi request reprint Chirality induction and protonation-induced molecular motions in helical molecular strands
    Elena Kolomiets
    Institut de Science et d Ingénierie Supramoléculaires ISIS, 8, allee Gaspard Monge, BP 70028, 67083 Strasbourg Cedex, France
    Chemistry 13:5466-79. 2007
  2. ncbi request reprint In situ generation and screening of a dynamic combinatorial carbohydrate library against concanavalin A
    O Ramström
    Laboratoire de Chimie Supramoléculaire ISIS Université Louis Pasteur CNRS 4 rue Blaise Pascal, 67000 Strasbourg, France
    Chembiochem 1:41-8. 2000
  3. ncbi request reprint Toward self-organization and complex matter
    Jean Marie Lehn
    Institut de Science et d Ingénierie Supramoléculaires ISIS, Universite Louis Pasteur, 67000 Strasbourg, and Collège de France, 75005 Paris, France
    Science 295:2400-3. 2002
  4. pmc Toward complex matter: supramolecular chemistry and self-organization
    Jean Marie Lehn
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, 67000 Strasbourg, France
    Proc Natl Acad Sci U S A 99:4763-8. 2002
  5. doi request reprint Self-ordering of metallogrid complexes via directed hydrogen-bonding
    Artur R Stefankiewicz
    Institut de Science et d Ingenierie Supramoleculaires, Universite de Strasbourg, France
    Dalton Trans 41:13848-55. 2012
  6. ncbi request reprint Modulation of the supramolecular structure of G-quartet assemblies by dynamic covalent decoration
    Eric Buhler
    Laboratoire de Chimie Supramoleculaire, ISIS, UMR CNRS 7006, Universite Louis Pasteur, 8 allee Gaspard Monge, 67000 Strasbourg, France
    J Am Chem Soc 129:10058-9. 2007
  7. ncbi request reprint Supramolecular polymers generated from heterocomplementary monomers linked through multiple hydrogen-bonding arrays--formation, characterization, and properties
    Volker Berl
    Laboratoire de Chimie Supramoleculaire, ESA 7006 CNRS, ISIS, Universite Louis Pasteur, 4 rue Blaise Pascal, 67000 Strasbourg, France
    Chemistry 8:1227-44. 2002
  8. pmc Gelation-driven component selection in the generation of constitutional dynamic hydrogels based on guanine-quartet formation
    Nampally Sreenivasachary
    Laboratoire de Chimie Supramoleculaire, Institut de Science et d Ingénierie Supramoléculaires ISIS, Universite Louis Pasteur, 8 allee Gaspard Monge, BP 70028, 67083 Strasbourg Cedex, France
    Proc Natl Acad Sci U S A 102:5938-43. 2005
  9. ncbi request reprint DyNAs: constitutional dynamic nucleic acid analogues
    Nampally Sreenivasachary
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, 8 allee Gaspard Monge, 67000 Strasbourg, France
    Chemistry 12:8581-8. 2006
  10. ncbi request reprint Dynamic chemical devices: generation of reversible extension/contraction molecular motion by ion-triggered single/double helix interconversion
    Mihail Barboiu
    Laboratoire de Chimie Supramoleculaire, ISIS Université Louis Pasteur, CNRS UMR 7006 4 rue Blaise Pascal, 67000 Strasbourg, France
    Chemistry 9:763-9. 2003

Collaborators

  • Adrian Mihail Stadler
  • Jack Harrowfield
  • Mihail Barboiu
  • Paolo Samorì
  • Mats Persson
  • O Ramström
  • Pierre Corvol
  • Gabin Sihn
  • Amor Hajri
  • Bruno Pitard
  • Sabine Castano
  • Teodor Silviu Balaban
  • Taridaporn Bunyapaiboonsri
  • Nampally Sreenivasachary
  • Artur R Stefankiewicz
  • Eric Buhler
  • Abderrahim Aissaoui
  • Jean Pierre Vigneron
  • Pierre Lehn
  • Anne Petitjean
  • Yves Ruff
  • Matthieu Sainlos
  • Noufissa Oudrhiri
  • Michelle Hauchecorne
  • Guillaume Rogez
  • Volker Berl
  • Claude Nicolau
  • Augustin M Madalan
  • Nabarun Roy
  • Anna K H Hirsch
  • Alexandre N Sobolev
  • Augustin Madalan
  • Kari Rissanen
  • Artur Ciesielski
  • Marc Aprahamian
  • Marc Schmutz
  • Louis A Cuccia
  • Ruth Greferath
  • Carolina D Duarte
  • Juan Ramirez
  • Sauveur Jean Candau
  • Giuseppina Pace
  • Lea Desigaux
  • Elena Kolomiets
  • Vladimir Setnicka
  • Myriam Linke-Schaetzel
  • Christopher K Haluska
  • W G Skene
  • Markus Kaiser
  • Valérie Marchi-Artzner
  • Dominique Luton
  • Antoine Richard
  • Erwan Kan
  • Sébastien Julia
  • Philippe Belmont
  • Laure Petit
  • Xiao Yu Cao
  • Stéphane P Vincent
  • Juhani Huuskonen
  • Cherif Y Akladios
  • Jean Marc Egly
  • Jacques Marescaux
  • Luc Soler
  • Konstantina Fylaktakidou
  • Felix Hanke
  • Gaétan Bour
  • Yeshayahu Talmon
  • Ellina Kesselman
  • Marc Drillon
  • Marie Noëlle Lalloz-Vogel
  • Olivier Lambert
  • Raphael Chevre
  • Emilie Letrou-Bonneval
  • David T Hickman
  • Annie K Powell
  • Marie Urbanová
  • Karin A Riske
  • Hélène Risler
  • Dominique Sarazin
  • Sreenivasachary Nampally
  • Rumiana Dimova
  • Karel Volka
  • Emilio Palomares
  • Sophie Bombard
  • Reinhard Lipowsky
  • Marie Paule Teulade-Fichou
  • Richard Khoury
  • Gernot Buth
  • Christopher E Anson
  • James D Durrant

Detail Information

Publications50

  1. ncbi request reprint Chirality induction and protonation-induced molecular motions in helical molecular strands
    Elena Kolomiets
    Institut de Science et d Ingénierie Supramoléculaires ISIS, 8, allee Gaspard Monge, BP 70028, 67083 Strasbourg Cedex, France
    Chemistry 13:5466-79. 2007
    ..Similar unfolding/folding motional processes take place in the L-tartro strands 15 and 16 upon protonation/deprotonation, with loss of helicity-induced circular dichroism on unfolding as shown for the protonated form 16(+)...
  2. ncbi request reprint In situ generation and screening of a dynamic combinatorial carbohydrate library against concanavalin A
    O Ramström
    Laboratoire de Chimie Supramoléculaire ISIS Université Louis Pasteur CNRS 4 rue Blaise Pascal, 67000 Strasbourg, France
    Chembiochem 1:41-8. 2000
    ..The present results illustrate the extention of the DCC approach to carbohydrate recognition groups, the generation of isoenergetic dynamic libraries, and the implementation of either adaptive or pre-equilibrated procedures...
  3. ncbi request reprint Toward self-organization and complex matter
    Jean Marie Lehn
    Institut de Science et d Ingénierie Supramoléculaires ISIS, Universite Louis Pasteur, 67000 Strasbourg, and Collège de France, 75005 Paris, France
    Science 295:2400-3. 2002
    ..Some of the conceptual advances and future challenges are profiled here...
  4. pmc Toward complex matter: supramolecular chemistry and self-organization
    Jean Marie Lehn
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, 67000 Strasbourg, France
    Proc Natl Acad Sci U S A 99:4763-8. 2002
  5. doi request reprint Self-ordering of metallogrid complexes via directed hydrogen-bonding
    Artur R Stefankiewicz
    Institut de Science et d Ingenierie Supramoleculaires, Universite de Strasbourg, France
    Dalton Trans 41:13848-55. 2012
    ..In the solid state various forms of spin-crossover behaviour can be observed between 1.8 and 300 K, which has been rationalised in terms of the varied forms of hydrogen-bonding possible in the crystalline state...
  6. ncbi request reprint Modulation of the supramolecular structure of G-quartet assemblies by dynamic covalent decoration
    Eric Buhler
    Laboratoire de Chimie Supramoleculaire, ISIS, UMR CNRS 7006, Universite Louis Pasteur, 8 allee Gaspard Monge, 67000 Strasbourg, France
    J Am Chem Soc 129:10058-9. 2007
  7. ncbi request reprint Supramolecular polymers generated from heterocomplementary monomers linked through multiple hydrogen-bonding arrays--formation, characterization, and properties
    Volker Berl
    Laboratoire de Chimie Supramoleculaire, ESA 7006 CNRS, ISIS, Universite Louis Pasteur, 4 rue Blaise Pascal, 67000 Strasbourg, France
    Chemistry 8:1227-44. 2002
    ..Such materials are, by nature, dynamic and present adaptive character in view of their ability to respond to external stimuli...
  8. pmc Gelation-driven component selection in the generation of constitutional dynamic hydrogels based on guanine-quartet formation
    Nampally Sreenivasachary
    Laboratoire de Chimie Supramoleculaire, Institut de Science et d Ingénierie Supramoléculaires ISIS, Universite Louis Pasteur, 8 allee Gaspard Monge, BP 70028, 67083 Strasbourg Cedex, France
    Proc Natl Acad Sci U S A 102:5938-43. 2005
    ..They extend constitutional dynamic chemistry to phase-organization and phase-transition events...
  9. ncbi request reprint DyNAs: constitutional dynamic nucleic acid analogues
    Nampally Sreenivasachary
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, 8 allee Gaspard Monge, 67000 Strasbourg, France
    Chemistry 12:8581-8. 2006
    ..It induces a change in size of the dynamic polymer, as it responds by an increase in degree of polymerization to an increase of the overall anionic charge introduced, that is, to the total electrostatic interaction...
  10. ncbi request reprint Dynamic chemical devices: generation of reversible extension/contraction molecular motion by ion-triggered single/double helix interconversion
    Mihail Barboiu
    Laboratoire de Chimie Supramoleculaire, ISIS Université Louis Pasteur, CNRS UMR 7006 4 rue Blaise Pascal, 67000 Strasbourg, France
    Chemistry 9:763-9. 2003
    ..The system 1,2-H/1,2-DH represents a dynamic chemical device undergoing ionic modulation of reversible molecular mechanical motion fueled by acid/base neutralization...
  11. doi request reprint Naphthyridine-based helical foldamers and macrocycles: synthesis, cation binding, and supramolecular assemblies
    Anne Petitjean
    Laboratoire de Chimie Supramoleculaire, Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, 8 allee Gaspard Monge, BP 70028, 67083 Strasbourg Cedex, France
    J Org Chem 73:2481-95. 2008
    ....
  12. ncbi request reprint Helical self-organization and hierarchical self-assembly of an oligoheterocyclic pyridine-pyridazine strand into extended supramolecular fibers
    Louis A Cuccia
    Laboratoire de Chimie Supramoléculaire ISIS, Université Louis Pasteur 4, rue Blaise Pascal, 67000 Strasbourg, France
    Chemistry 8:3448-57. 2002
    ..Compound 3 also forms mechanically stable two-dimensional Langmuir-Blodgett and cast thin films...
  13. pmc Dynamic chemical devices: modulation of contraction/extension molecular motion by coupled-ion binding/pH change-induced structural switching
    Mihail Barboiu
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, Centre National de la Recherche Scientifique Unité Mixte de Recherche 7006, 4 rue Blaise Pascal, 67000 Strasbourg, France
    Proc Natl Acad Sci U S A 99:5201-6. 2002
    ..It achieves a linear motor-type of action of very large stroke amplitude fueled by ionic processes...
  14. doi request reprint Subnanometer-resolved patterning of bicomponent self-assembled monolayers on Au(111)
    Giuseppina Pace
    ISIS CNRS UMR 7006 Université Louis Pasteur, 8 allee Gaspard Monge, 67000 Strasbourg, France
    Angew Chem Int Ed Engl 47:2484-8. 2008
  15. doi request reprint Myo-InositolTrisPyroPhosphate treatment leads to HIF-1α suppression and eradication of early hepatoma tumors in rats
    Marc Aprahamian
    Institut National pour Santé et Recherche Médicale, Unit 701, IRCAD Strasbourg, France
    Chembiochem 12:777-83. 2011
    ..ITPP did not affect hematologic parameters during treatment. The observations of in vivo tumor eradication suggest a significant clinical potential for ITPP in cancer therapy...
  16. ncbi request reprint Combined suicide gene therapy for pancreatic peritoneal carcinomatosis using BGTC liposomes
    Amor Hajri
    INSERM U375, IRCAD, 1 Place de l Hopital, BP 426, 67091 Strasbourg, France
    Cancer Gene Ther 11:16-27. 2004
    ....
  17. doi request reprint Grid-double-helicate interconversion
    Adrian Mihail Stadler
    Institut de Science et d Ingenierie Supramoleculaires, CNRS UMR 7006, 8 allee Gaspard Monge, Strasbourg, 67083, France
    Chem Commun (Camb) 49:5733-5. 2013
    ..During the studies, in order to ascertain the structure of Cu(I) complexes, a heteroleptic binuclear Cu(I) double helicate was generated...
  18. ncbi request reprint Conjecture: imines as unidirectional photodriven molecular motors-motional and constitutional dynamic devices
    Jean Marie Lehn
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, 8 allee Gaspard Monge, 67000 Strasbourg, France
    Chemistry 12:5910-5. 2006
    ..As they are also able to undergo exchange of the carbonyl and amine partners, they present constitutional dynamics. Thus, imine-type compounds are double dynamic, motional, and constitutional devices...
  19. ncbi request reprint Glycodynamers: dynamic analogs of arabinofuranoside oligosaccharides
    Yves Ruff
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, BP 70028, 67083 Strasbourg, France
    Biopolymers 89:486-96. 2008
    ..Their size and composition can be tuned by component exchange emphasizing their constitutionally dynamic character. They represent dynamic versions of biopolymers, biodynamers...
  20. doi request reprint Biodynamers: self-organization-driven formation of doubly dynamic proteoids
    Anna K H Hirsch
    Institut de Science et d Ingénierie Supramoléculaires ISIS, Universite de Strasbourg, 8, allee Gaspard Monge, 67000 Strasbourg, France
    J Am Chem Soc 134:4177-83. 2012
    ..The system described displays nucleation-elongation behavior driven by hydrophobic effects and represents a model for the operation of adaptation processes in the evolution of complex matter...
  21. ncbi request reprint Structural selection in G-quartet-based hydrogels and controlled release of bioactive molecules
    Nampally Sreenivasachary
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, 8 allee Gaspard Monge, F 67000 Strasbourg, France
    Chem Asian J 3:134-9. 2008
    ..Hydrogels thus offer a promising medium for highly selective, controlled release of bioactive substances...
  22. ncbi request reprint Solid-state self-assembly of polymeric double helicates leading to linear arrays of silver(I) ions and reversible strand/double helix interconversion in solution
    Adrian Mihail Stadler
    Laboratoire de Chimie Supramoleculaire, ISIS, Universite Louis Pasteur, 8 allee Gaspard Monge, BP 70028, 67083 Strasbourg Cedex, France
    Chemistry 13:59-68. 2007
    ..Progressive addition of silver(I) ions to a 1:1 mixture of 1 and 5 leads to the preferential formation of the double helicate 2 over the grid complex 6, illustrating a process of self-organisation with selection of the correct ligand...
  23. ncbi request reprint Transport of the highly charged myo-inositol hexakisphosphate molecule across the red blood cell membrane: a phase transfer and biological study
    Stéphane P Vincent
    Laboratoire de Chimie Supramoleculaire, ISIS Université Louis Pasteur CNRS, 4 rue Blaise Pascal, 67000 Strasbourg, France
    Bioorg Med Chem 10:2825-34. 2002
    ..A qualitative correlation was found between the partitioning experiments and the biological evaluations performed on whole blood...
  24. doi request reprint myo-Inositol trispyrophosphate: a novel allosteric effector of hemoglobin with high permeation selectivity across the red blood cell plasma membrane
    Carolina D Duarte
    Institut de Science et d Ingenierie Supramoleculaires, Universite de Strasbourg, 8 allee Gaspard Monge, 67000 Strasbourg, France
    Chembiochem 11:2543-8. 2010
    ..72×10(-5) M. All data obtained indicate that ITPP uptake is mediated by band 3 protein and is thus highly tissue-selective towards RBCs, a feature of major importance for its potential therapeutic use...
  25. doi request reprint Rigid dimers formed through strong interdigitated H-bonds yield compact 1D supramolecular helical polymers
    Artur Ciesielski
    ISIS CNRS UMR 7006, Universite de Strasbourg, 8 allee Gaspard Monge, 67000 Strasbourg, France
    Small 7:342-50. 2011
    ....
  26. ncbi request reprint Ferromagnetic Coupling in Copper(II) [2 × 2] Grid-like Complexes
    Augustin M Madalan
    Institut de Science et d Ingenierie Supramoleculaires, Universite de Strasbourg, 8 allee Gaspard Monge, 67000 Strasbourg, France
    Inorg Chem 53:4275-7. 2014
    ..Two copper(II) [2 × 2] grid-like complexes were synthesized and structurally characterized. Investigation of the magnetic properties showed for both the occurrence of intramolecular ferromagnetic interactions. ..
  27. ncbi request reprint Copper(II) dinuclear pyrazine-based rack-type complexes: preparation, structure, and magnetic properties
    Juan Ramirez
    Laboratoire de Chimie Supramoleculaire, Institut de Science et d Ingenierie Supramoleculaires, Universite de Strasbourg, 8 allee Gaspard Monge, Strasbourg 67083, France
    Inorg Chem 48:2456-63. 2009
    ..The solid-state structures of these complexes were determined by X-ray crystallography. The magnetic measurements performed on the complexes revealed the presence of antiferromagnetic intramolecular interactions...
  28. doi request reprint Constitutional dynamic chemistry: bridge from supramolecular chemistry to adaptive chemistry
    Jean Marie Lehn
    Institut de Science et d Ingenierie Supramoleculaires, Universite de Strasbourg, Strasbourg, France
    Top Curr Chem 322:1-32. 2012
    ..The merging of the features: -information and programmability, -dynamics and reversibility, -constitution and structural diversity, points to the emergence of adaptive and evolutive chemistry, towards a chemistry of complex matter...
  29. ncbi request reprint Aminoglycoside-derived cationic lipids as efficient vectors for gene transfection in vitro and in vivo
    Philippe Belmont
    Laboratoire de Chimie des Interactions Moléculaires, College de France, 11 place Marcelin Berthelot, 75005 Paris, France
    J Gene Med 4:517-26. 2002
    ..Indeed, aminoglycosides, which are natural polyamines known to bind to nucleic acids, provide a favorable scaffold for the synthesis of a variety of cationic lipids because of their structural features and multifunctional nature...
  30. ncbi request reprint Structural and metallo selectivity in the assembly of [2 × 2] grid-type metallosupramolecular species: Mechanisms and kinetic control
    Artur R Stefankiewicz
    Institut de Science et d Ingenierie Supramoleculaires, Universite de Strasbourg, 8, allee Gaspard Monge, 67083, Strasbourg, France
    Dalton Trans 40:12320-32. 2011
    ..This stereoselectivity in the crystalline lattice is associated with interactions between the cation and triflate anions which can again be analysed in terms of the Coupe du Roi concept...
  31. doi request reprint The tris-urea motif and its incorporation into polydimethylsiloxane-based supramolecular materials presenting self-healing features
    Nabarun Roy
    Laboratoire de Chimie Supramoleculaire, ISIS, Universite de Strasbourg, 8, allee Gaspard Monge, 67000 Strasbourg, France
    Chemistry 19:8814-20. 2013
    ..This approach gives access to a broad spectrum of materials of varying flexibility by appropriate selection of the bis-isocyanate component that forms the polymer backbone. ..
  32. ncbi request reprint Glycodynamers: dynamic polymers bearing oligosaccharides residues - generation, structure, physicochemical, component exchange, and lectin binding properties
    Yves Ruff
    Laboratoire de Chimie Supramoleculaire, ISIS, Universite de Strasbourg, allee Gaspard Monge, 67000 Strasbourg, France, Laboratoire Matiere et Systemes Complexes MSC, UMR CNRS 7057, Batiment Condorcet, Universite Paris Diderot Paris 7, 75205 Paris Cedex 13, France, and Department of Chemical Engineering, Technion Israel Institute of Technology, Haifa 32000, Israel
    J Am Chem Soc 132:2573-84. 2010
    ..Constitution-dependent binding of these glycodynamers to a lectin, peanut agglutinin, has been demonstrated...
  33. ncbi request reprint Formation of RACK- and grid-type metallosupramolecular architectures and generation of molecular motion by reversible uncoiling of helical ligand strands
    Adrian Mihail Stadler
    Institut de Science et d Ingenierie Supramoleculaires, Universite Louis Pasteur, 8 allee Gaspard Monge, 67000 Strasbourg, France
    Chemistry 12:4503-22. 2006
    ..It has been integrated in an acid-base neutralisation fuelled process, which links the extension/contraction of the ligand strands to alternating changes in pH...
  34. ncbi request reprint Anti-angiogenic properties of myo-inositol trispyrophosphate in ovo and growth reduction of implanted glioma
    Gabin Sihn
    Laboratoire de Pathologie Vasculaire et Endocrinologie Rénale, INSERM U36, College de France, 11, place Marcelin Berthelot, 75005 Paris, France
    FEBS Lett 581:962-6. 2007
    ..These results point out the potential of ITPP for the development of a new class of anti-angiogenic and anti-cancer compounds...
  35. ncbi request reprint Progress in gene delivery by cationic lipids: guanidinium-cholesterol-based systems as an example
    Abderrahim Aissaoui
    INSERM U458, Hĵpital Robert Debré, Paris, France
    Curr Drug Targets 3:1-16. 2002
    ....
  36. ncbi request reprint Dynamic chemical devices: photoinduced electron transfer and its ion-triggered switching in nanomechanical butterfly-type bis(porphyrin)terpyridines
    Myriam Linke-Schaetzel
    Forschungszentrum Karlsruhe, Institute for Nanotechnology, Postfach 3640, 76021 Karlsruhe Germany
    Chemistry 12:1931-40. 2006
    ..Both energy- and electron-transfer processes can be controlled opening a means of improving the on/off ratio in future constructs...
  37. ncbi request reprint Gene transfection into fetal sheep airways in utero using guanidinium-cholesterol cationic lipids
    Dominique Luton
    Maternité, Hopital Robert Debre, AP HP, 48 Boulevard Serurier, 75019 Paris, France
    J Gene Med 6:328-36. 2004
    ....
  38. ncbi request reprint Drug discovery by dynamic combinatorial libraries
    Olof Ramström
    Laboratoire de Chimie Supramoleculaire, ISIS Université Louis Pasteur, 4 rue Blaise Pascal, F 67000, Strasbourg, France
    Nat Rev Drug Discov 1:26-36. 2002
    ....
  39. ncbi request reprint 2-Aminopyrimidine directed self-assembly of zinc porphyrins containing bulky 3,5-di-tert-butylphenyl groups
    Teodor Silviu Balaban
    Forschungszentrum Karlsruhe, Institute for Nanotechnology, Postfach 3640, D 76021 Karlsruhe, Germany
    J Am Chem Soc 125:4233-9. 2003
    ..The di(2-aminopyrimidin-5-yl) derivative forms strongly scattering solutions, which upon standing form green flocculate precipitates, reminiscent of shaken suspensions of bacteriochlorophyll c...
  40. ncbi request reprint Investigation of guanosine-quartet assemblies by vibrational and electronic circular dichroism spectroscopy, a novel approach for studying supramolecular entities
    Vladimir Setnicka
    Institute of Chemical Technology, Technicka 5, 166 28 Prague 6, Czech Republic
    Chemistry 12:8735-43. 2006
    ....
  41. ncbi request reprint Dynamic combinatorial carbohydrate libraries: probing the binding site of the concanavalin A lectin
    Olof Ramström
    Laboratoire de Chimie Supramoleculaire, ISIS Université Louis Pasteur, 8, allee Gaspard Monge, BP 70028, 67083 Strasbourg Cedex, France
    Chemistry 10:1711-5. 2004
    ..Dynamic deconvolution allowed the efficient identification of the structural features required for binding to Concanavalin A and the selection of a strong binder, a tritopic mannoside, showing an IC(50)-value of 22 microM...
  42. ncbi request reprint Self-organization of oligomeric helical stacks controlled by substrate binding in a tobacco mosaic virus like self-assembly process
    Anne Petitjean
    Laboratoire de Chimie Supramoleculaire, ISIS, 8 allee Gaspard Monge, BP 70028, 67083 Strasbourg, France
    Angew Chem Int Ed Engl 43:3695-9. 2004
  43. pmc Time scales of membrane fusion revealed by direct imaging of vesicle fusion with high temporal resolution
    Christopher K Haluska
    Max Planck Institute of Colloids and Interfaces, Science Park Golm, 14424 Potsdam, Germany
    Proc Natl Acad Sci U S A 103:15841-6. 2006
    ..This velocity indicates that the initial formation of a single fusion neck can be completed in a few hundred nanoseconds...
  44. ncbi request reprint Novel cationic lipids incorporating an acid-sensitive acylhydrazone linker: synthesis and transfection properties
    Abderrahim Aissaoui
    INSERM U458, Hopital Robert Debre, AP HP, 48 Boulevard Serurier, 75019 Paris, France
    J Med Chem 47:5210-23. 2004
    ....
  45. pmc Fusogenic supramolecular vesicle systems induced by metal ion binding to amphiphilic ligands
    Antoine Richard
    Laboratoire de Chimie des Interactions Moléculaires and Laboratoire de Physique de la Matière Condensée, College de France, 11 place Marcelin Berthelot, 75231 Paris Cedex 05, France
    Proc Natl Acad Sci U S A 101:15279-84. 2004
    ..They provide an approach to the design of artificial "tissue-mimetics" through the generation of polyvesicular arrays of defined architecture and to the control of their functional properties...
  46. ncbi request reprint Aminoglycoside-quinacridine conjugates: towards recognition of the P6.1 element of telomerase RNA
    Markus Kaiser
    Laboratoire de Chimie des Interactions Moléculaires, CNRS UPR 285, College de France
    Chembiochem 7:321-9. 2006
    ..Taken together, the data suggest a binding of TD1 inside the hairpin at the stem-loop junction. The same trends are observed with paromomycin and kanamycin analogues but with a lower affinity...
  47. pmc Self-assembled lamellar complexes of siRNA with lipidic aminoglycoside derivatives promote efficient siRNA delivery and interference
    Lea Desigaux
    Institut National de la Sante et de la Recherche Medicale, U533, F 44035 Nantes, France
    Proc Natl Acad Sci U S A 104:16534-9. 2007
    ..These results clearly show that lipidic aminoglycoside derivatives constitute a versatile class of siRNA nanocarriers allowing efficient gene silencing...
  48. ncbi request reprint Kanamycin A-derived cationic lipids as vectors for gene transfection
    Matthieu Sainlos
    Laboratoire de Chimie des Interactions Moléculaires, College de France, CNRS UPR 285, 11 place Marcelin Berthelot, 75231 Paris Cedex 05, France
    Chembiochem 6:1023-33. 2005
    ..Furthermore, a combination of transfection and physicochemical data revealed that some modifications of the constitutive subunits of kanamycin A-based vectors were associated with substantial changes in their transfection properties...
  49. ncbi request reprint Selective product amplification of thymine photodimer by recognition-directed supramolecular assistance
    W G Skene
    Laboratoire de Chimie Supramoleculaire, ISIS Université Louis Pasteur, 8, allee Gaspard Monge, BP 70028, 67083, Strasbourg Cedex, France
    Org Biomol Chem 4:3652-63. 2006
    ..Complementary donor and acceptor hydrogen bonding induced positioning of the two substrates and steric hindrance within the template clefts are responsible for the selective product formation...
  50. doi request reprint Brewster angle microscopy and PMIRRAS study of DNA interactions with BGTC, a cationic lipid used for gene transfer
    Sabine Castano
    UMR 5248 CBMN, CNRS Universite Bordeaux 1 ENITAB, IECB, 2 rue Robert Escarpit, 33607 Pessac, France
    Langmuir 24:9598-606. 2008
    ..These results allow a better understanding of the mechanisms underlying the formation of the supramolecular BGTC-DNA complexes efficient for gene transfection...