Vincent Legagneux

Summary

Country: France

Publications

  1. ncbi request reprint Multiple roles of Condensins: a complex story
    Vincent Legagneux
    UMR 6061 CNRS, Universite de Rennes 1, Faculte de Medecine, 2 Avenue du Pr Leon Bernard, 35043 Rennes Cedex, France
    Biol Cell 96:201-13. 2004
  2. ncbi request reprint Introduction to chromosome dynamics in mitosis
    Erwan Watrin
    UMR 6061 CNRS, Universite de Rennes I, Faculte de Medecine, 2 Avenue du Pr Leon Bernard, 35043 Rennes Cedex, France
    Biol Cell 95:507-13. 2003
  3. ncbi request reprint Expression and functional dynamics of the XCAP-D2 condensin subunit in Xenopus laevis oocytes
    Erwan Watrin
    UMR 6061 CNRS, Universite de Rennes 1, Faculte de Medecine, 2 avenue Léon Bernard, 35043 Rennes Cedex, France
    J Biol Chem 278:25708-15. 2003
  4. ncbi request reprint c-Jun ARE targets mRNA deadenylation by an EDEN-BP (embryo deadenylation element-binding protein)-dependent pathway
    Luc Paillard
    CNRS UMR 6061, Universite de Rennes 1, Faculte de Medecine, 2 avenue Léon Bernard, 35043 Rennes Cedex, France
    J Biol Chem 277:3232-5. 2002
  5. ncbi request reprint A functional deadenylation assay identifies human CUG-BP as a deadenylation factor
    Luc Paillard
    CNRS UMR 6061, Faculte de Medecine, Universite Rennes 1, 2, avenue Léon Bernard, CS 34317, 35043 cedex, Rennes, France
    Biol Cell 95:107-13. 2003
  6. doi request reprint The rotaviral NSP3 protein stimulates translation of polyadenylated target mRNAs independently of its RNA-binding domain
    Cecile Keryer-Bibens
    Universite de Rennes 1, IFR 140, Institut de Génétique et Développement de Rennes, 35000 Rennes, France
    Biochem Biophys Res Commun 390:302-6. 2009
  7. doi request reprint Post-transcriptional controls - adding a new layer of regulation to clock gene expression
    Marie Cibois
    Universite de Rennes 1, Universite Europeenne de Bretagne, Institut Federatif de Recherche 140, France
    Trends Cell Biol 20:533-41. 2010
  8. pmc Reverse genetics in eukaryotes
    Serge Hardy
    Universite de Rennes 1, Universite Europeenne de Bretagne, Institut Federatif de Recherche 140, Rennes, France
    Biol Cell 102:561-80. 2010
  9. doi request reprint Chromosome wide analysis of CUGBP1 binding sites identifies the tetraspanin CD9 mRNA as a target for CUGBP1-mediated down-regulation
    Olivier Le Tonquèze
    CNRS, UMR 6061 Institut de Génétique et Développement de Rennes, Expression Génétique et Développement, Universite de Rennes I, IFR 140 GFAS, 2 Avenue du Professeur Leon Bernard, CS 34317, 35043 Rennes Cedex, France
    Biochem Biophys Res Commun 394:884-9. 2010
  10. ncbi request reprint Nucleolar association of pEg7 and XCAP-E, two members of Xenopus laevis condensin complex in interphase cells
    Rustem Uzbekov
    Groupe Structure Dynamique de la Chromatine, CNRS, UMR 6061, Faculte de Medicine, 35043 Rennes, France
    J Cell Sci 116:1667-78. 2003

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Multiple roles of Condensins: a complex story
    Vincent Legagneux
    UMR 6061 CNRS, Universite de Rennes 1, Faculte de Medecine, 2 Avenue du Pr Leon Bernard, 35043 Rennes Cedex, France
    Biol Cell 96:201-13. 2004
    ..However, the exact contribution of each subunit remains largely elusive as well as the functional interplay between Condensin I and Condensin II...
  2. ncbi request reprint Introduction to chromosome dynamics in mitosis
    Erwan Watrin
    UMR 6061 CNRS, Universite de Rennes I, Faculte de Medecine, 2 Avenue du Pr Leon Bernard, 35043 Rennes Cedex, France
    Biol Cell 95:507-13. 2003
    ..The second part will present the current understanding of chromosome condensation and segregation during mitosis in higher eukaryotes. Finally, we will underline the links that exist between replication and mitosis...
  3. ncbi request reprint Expression and functional dynamics of the XCAP-D2 condensin subunit in Xenopus laevis oocytes
    Erwan Watrin
    UMR 6061 CNRS, Universite de Rennes 1, Faculte de Medecine, 2 avenue Léon Bernard, 35043 Rennes Cedex, France
    J Biol Chem 278:25708-15. 2003
    ..This apparent discrepancy is discussed in light of current knowledge on chromosome dynamics...
  4. ncbi request reprint c-Jun ARE targets mRNA deadenylation by an EDEN-BP (embryo deadenylation element-binding protein)-dependent pathway
    Luc Paillard
    CNRS UMR 6061, Universite de Rennes 1, Faculte de Medecine, 2 avenue Léon Bernard, 35043 Rennes Cedex, France
    J Biol Chem 277:3232-5. 2002
    ..Together, these results identify CUG-BP as a plausible deadenylation factor responsible for the post-transcriptional control of c-Jun proto-oncogene mRNA in mammalian cells...
  5. ncbi request reprint A functional deadenylation assay identifies human CUG-BP as a deadenylation factor
    Luc Paillard
    CNRS UMR 6061, Faculte de Medecine, Universite Rennes 1, 2, avenue Léon Bernard, CS 34317, 35043 cedex, Rennes, France
    Biol Cell 95:107-13. 2003
    ..The results presented here identify CUG-BP-dependent deadenylation as a potential cytoplasmic target for this trans-dominant effect...
  6. doi request reprint The rotaviral NSP3 protein stimulates translation of polyadenylated target mRNAs independently of its RNA-binding domain
    Cecile Keryer-Bibens
    Universite de Rennes 1, IFR 140, Institut de Génétique et Développement de Rennes, 35000 Rennes, France
    Biochem Biophys Res Commun 390:302-6. 2009
    ..These results show that NSP3 can act as a translational enhancer even on a polyadenylated mRNA that should be a substrate for PABP1...
  7. doi request reprint Post-transcriptional controls - adding a new layer of regulation to clock gene expression
    Marie Cibois
    Universite de Rennes 1, Universite Europeenne de Bretagne, Institut Federatif de Recherche 140, France
    Trends Cell Biol 20:533-41. 2010
    ..We conclude that both constitutive and cyclic post-transcriptional controls underpin clock function...
  8. pmc Reverse genetics in eukaryotes
    Serge Hardy
    Universite de Rennes 1, Universite Europeenne de Bretagne, Institut Federatif de Recherche 140, Rennes, France
    Biol Cell 102:561-80. 2010
    ..Genome-wide collections of mutants or inactivated models obtained in several species by these approaches have been made and will help decipher gene functions in the post-genomic era...
  9. doi request reprint Chromosome wide analysis of CUGBP1 binding sites identifies the tetraspanin CD9 mRNA as a target for CUGBP1-mediated down-regulation
    Olivier Le Tonquèze
    CNRS, UMR 6061 Institut de Génétique et Développement de Rennes, Expression Génétique et Développement, Universite de Rennes I, IFR 140 GFAS, 2 Avenue du Professeur Leon Bernard, CS 34317, 35043 Rennes Cedex, France
    Biochem Biophys Res Commun 394:884-9. 2010
    ..In a number of cancers, the tetraspanin CD9 is down-regulated, an event correlated with a bad prognostic. Using a combination of biochemical approaches and CUGBP1 knockdown, we showed that CUGBP1 directly controls CD9 expression...
  10. ncbi request reprint Nucleolar association of pEg7 and XCAP-E, two members of Xenopus laevis condensin complex in interphase cells
    Rustem Uzbekov
    Groupe Structure Dynamique de la Chromatine, CNRS, UMR 6061, Faculte de Medicine, 35043 Rennes, France
    J Cell Sci 116:1667-78. 2003
    ..The data suggest a novel interphase function of condensin subunits in spatial organization of the nucleolus and/or ribosome biogenesis...
  11. pmc Contribution of hCAP-D2, a non-SMC subunit of condensin I, to chromosome and chromosomal protein dynamics during mitosis
    Erwan Watrin
    Research Institute of Molecular Pathology IMP, Dr Bohr Gasse 7, 1030 Vienna, Austria
    Mol Cell Biol 25:740-50. 2005
    ..This suggests that condensin I is involved in the correct attachment between chromosome kinetochores and microtubules of the mitotic spindle. These results are discussed relative to the effects of depleting both condensin complexes...
  12. ncbi request reprint Distribution of XCAP-E and XCAP-D2 in the Xenopus oocyte nucleus
    Brent Beenders
    Department of Cell and Structural Biology, University of Illinois, Urbana, Illinois 61801, USA
    Chromosome Res 11:549-64. 2003
    ..The presence of two condensins in CBs might extend such a role of assembly to chromatin macromolecular components as well...