Suzie Lefebvre

Summary

Country: France

Publications

  1. ncbi request reprint The role of the SMN gene in proximal spinal muscular atrophy
    S Lefebvre
    Unite de Recherches sur les Handicaps Genetiques de l Enfant, INSERM U393, IFREM, Institut Necker, Hopital des Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Hum Mol Genet 7:1531-6. 1998
  2. ncbi request reprint A novel association of the SMN protein with two major non-ribosomal nucleolar proteins and its implication in spinal muscular atrophy
    Suzie Lefebvre
    INSERM U393, IRNEM Institute, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Hum Mol Genet 11:1017-27. 2002
  3. ncbi request reprint Mapping of autosomal recessive chronic distal spinal muscular atrophy to chromosome 11q13
    Louis Viollet
    Unite de Recherches sur les Handicaps Genetiques de l Enfant, INSERM U 393, Institut Necker Enfants Malades, Paris, France
    Ann Neurol 51:585-92. 2002
  4. ncbi request reprint Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells
    Benoît Renvoisé
    Laboratoire de Biologie Cellulaire des Membranes, Institut Jacques Monod IJM, UMR 7592 CNRS Universités Paris 6 et 7, 2 place Jussieu, 75251 Paris Cedex 05, France
    J Cell Sci 119:680-92. 2006

Collaborators

Detail Information

Publications4

  1. ncbi request reprint The role of the SMN gene in proximal spinal muscular atrophy
    S Lefebvre
    Unite de Recherches sur les Handicaps Genetiques de l Enfant, INSERM U393, IFREM, Institut Necker, Hopital des Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Hum Mol Genet 7:1531-6. 1998
    ..These observations emphasized the difficulty in elucidating the function of any novel protein. Therefore, multidisciplinary approaches are required to understand the pathogenesis of SMA...
  2. ncbi request reprint A novel association of the SMN protein with two major non-ribosomal nucleolar proteins and its implication in spinal muscular atrophy
    Suzie Lefebvre
    INSERM U393, IRNEM Institute, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    Hum Mol Genet 11:1017-27. 2002
    ..These findings suggest that altered assembly and/or stability of ribonucleoprotein complexes may contribute to the pathophysiological processes in SMA...
  3. ncbi request reprint Mapping of autosomal recessive chronic distal spinal muscular atrophy to chromosome 11q13
    Louis Viollet
    Unite de Recherches sur les Handicaps Genetiques de l Enfant, INSERM U 393, Institut Necker Enfants Malades, Paris, France
    Ann Neurol 51:585-92. 2002
    ..In addition, the high intrafamilial variability in age at onset raises the question of whether nonallelic modifying genes could be involved in chronic distal spinal muscular atrophy...
  4. ncbi request reprint Distinct domains of the spinal muscular atrophy protein SMN are required for targeting to Cajal bodies in mammalian cells
    Benoît Renvoisé
    Laboratoire de Biologie Cellulaire des Membranes, Institut Jacques Monod IJM, UMR 7592 CNRS Universités Paris 6 et 7, 2 place Jussieu, 75251 Paris Cedex 05, France
    J Cell Sci 119:680-92. 2006
    ..These results indicate that direct and indirect mechanisms regulate localization of SMN in Cajal bodies...