- Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasiaFranck Lebrin
Institut National de la Santé et de la Recherche Médicale U833, College de France, Paris, France
Nat Med 16:420-8. 2010..Our findings demonstrate the ability of thalidomide to induce vessel maturation, which may be useful as a therapeutic strategy for the treatment of vascular malformations...
- Endoglin-mediated vascular remodeling: mechanisms underlying hereditary hemorrhagic telangiectasiaFranck Lebrin
Laboratory of Embryonic and Pathological Angiogenesis, College de France, Paris, France
Trends Cardiovasc Med 18:25-32. 2008..We highlight where the controversies on underlying molecular mechanisms currently lie and indicate areas of present research focus...
- Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesisMelanie Eyries
INSERM UMRS 525, Universite Pierre et Marie Curie, Paris, France
Circ Res 103:432-40. 2008..The hypoxia-induced apelin expression may, thus, provide a new mechanism involved in adaptive physiological and pathophysiological response of vascular cells to low oxygen level...