Research Topics
Species | Yann Le StratSummaryCountry: France Publications
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Detail Information
Publications
Levetiracetam in the treatment of alcohol dependence: toward the end of the story?Yann Le Strat
Department of Psychiatry, Louis Mourier Hospital, AP HP, Colombes, France
Alcohol Clin Exp Res 36:1309-10. 2012..Levetiracetam exhibited 2 promising results in preclinical studies as well as in treating alcohol withdrawal in humans. Two open-label trials suggested that levetiracetam may be efficient in alcohol-related disorder...- Child marriage in the United States and its association with mental health in womenYann Le Strat
Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Pediatrics 128:524-30. 2011..This article presents nationally representative data on the prevalence, sociodemographic correlates, and psychiatric comorbidity of child marriage among women in the United States... - [The role of genetic factors on the link between stress and alcohol use: the example of CRH-R1]Yann Le Strat
Assistance Publique Hopitaux de Paris, Hopital Louis Mourier, service de psychiatrie du Professeur Adès, Colombes, France
Presse Med 41:32-6. 2012..The present review emphasizes the relationship between variations of genes coding for proteins involved in physiological answer to stress and alcohol use, within the hypothesis of a gene x environment interaction... - Obesity and cannabis use: results from 2 representative national surveysYann Le Strat
Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Am J Epidemiol 174:929-33. 2011..Additionally, after adjustment for sex and age, the use of cannabis was associated with body mass index differences in both samples. The authors conclude that the prevalence of obesity is lower in cannabis users than in nonusers... - Prevalence and correlates of major depressive episode in pregnant and postpartum women in the United StatesYann Le Strat
Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
J Affect Disord 135:128-38. 2011..This study presents nationally representative data on the prevalence, correlates, and psychiatric comorbidities of depression in women during pregnancy and postpartum in the United States... - Hazardous drinking is associated with a lower risk of coronary heart disease: results from a national representative sampleYann Le Strat
INSERM U894, Centre de psychiatrie et Neurosciences, 2 ter rue d Alesia, Paris, France
Am J Addict 20:257-63. 2011..Our study shows that alcohol may have cardioprotective effects not only in moderate drinkers, but also in individuals with patterns of use traditionally considered as hazardous. .. - How generalisable to community samples are clinical trial results for treatment of nicotine dependence: a comparison of common eligibility criteria with respondents of a large representative general population surveyYann Le Strat
Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Tob Control 20:338-43. 2011..To examine the generalisability of findings from clinical trials of individuals with nicotine dependence to a large general population sample... - In alcohol-dependent drinkers, what does the presence of nicotine dependence tell us about psychiatric and addictive disorders comorbidity?Yann Le Strat
INSERM, Unit 894, Centre Psychiatrie et Neurosciences, Faculte de Medecine, Universite Paris Descartes, 2 ter, rue d Alésia 75014 Paris, France
Alcohol Alcohol 45:167-72. 2010..To examine the pattern of psychiatric comorbidity associated with nicotine dependence among alcohol-dependent respondents in the general population... - A new definition of early age at onset in alcohol dependenceYann Le Strat
INSERM U894 U675, Centre Psychiatrie et Neurosciences, 75014 Paris, France
Drug Alcohol Depend 108:43-8. 2010.... - First positive reactions to cannabis constitute a priority risk factor for cannabis dependenceYann Le Strat
INSERM U675 U894, Centre Psychiatrie et Neurosciences, Universite Paris V, Paris, France
Addiction 104:1710-7. 2009..To assess the association between first reactions to cannabis and the risk of cannabis dependence... - Sex differences in shoplifting: results from a national sampleNicolas Hoertel
Service de Psychiatrie, Hopital Louis Mourier, Assistance Publique Hopitaux de Paris, Colombes, France
J Nerv Ment Dis 200:728-33. 2012..Shoplifting could be more a part of the externalizing spectrum disorders rather than the internalizing spectrum disorders in women compared to men... 
Estrogen receptor 1 gene (ESR1) is associated with restrictive anorexia nervosaAudrey Versini
INSERM U894 Team 1, Center of Psychiatry and Neurosciences, University Paris Descartes, 2ter rue d Alesia, Paris, France
Neuropsychopharmacology 35:1818-25. 2010..In particular, ESR1 gene confers a high risk of vulnerability to the restrictive subtype of AN, and suggests that the estrogen pathway has to be further analyzed in AN...- Prevalence of subthreshold hypomania and impact on internal validity of RCTs for major depressive disorder: results from a national epidemiological sampleNicolas Hoertel
Assistance Publique Hopitaux de Paris AP HP, Hopital Corentin Celton, Service de Psychiatrie, Issy les Moulineaux, France
PLoS ONE 8:e55448. 2013.... - Generalizability of clinical trial results for generalized anxiety disorder to community samplesNicolas Hoertel
Service de Psychiatrie, Hopital Louis Mourier, Assistance Publique Hopitaux de Paris APHP, Colombes, France
Depress Anxiety 29:614-20. 2012..The present study examines the generalizability of pharmacological and psychotherapy clinical trials' results of individuals with DSM-IV GAD to a large community sample... - Genetics of dopamine receptors and drug addictionPhilip Gorwood
Groupe Hospitalier Sainte Anne, CMME, 100 rue de la Santé, Paris, France
Hum Genet 131:803-22. 2012.... - Association between peptic ulcer and personality disorders in a nationally representative US sampleJean Pierre Schuster
Assistance Publique Hopitaux de Paris, Department of Psychiatry, Corentin Celton Hospital, Issy les Moulineaux, France
Psychosom Med 72:941-6. 2010..To assess the association between peptic ulcer and a wide range of personality disorders in a large sample representative of the general population in the United States... - Genetics of dopamine receptors and drug addiction: a comprehensive reviewBernard Le Foll
Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, University of Toronto, Toronto, Canada
Behav Pharmacol 20:1-17. 2009..Overall, this review indicates that different aspects of the addiction phenotype are critically influenced by dopaminergic receptors and that variants of those genes seem to influence some addiction phenotypes in humans... - Are subjects in treatment trials of panic disorder representative of patients in routine clinical practice? Results from a national sampleNicolas Hoertel
AP HP, Hopital Louis Mourier, Service de psychiatrie et addictologie, 178 Rue Renouillers, Colombes Cedex 92701, France
J Affect Disord 146:383-9. 2013..The present study sought to quantify the generalizability of clinical trials' results of individuals with DSM-IV panic disorder (PD) to a large community sample... - Gender effects in bullying: results from a national sampleNicolas Hoertel
Service de Psychiatrie, Hopital Corentin Celton, Assistance Publique Hopitaux de Paris AP HP, 92130, Issy les Moulineaux, France
Psychiatry Res 200:921-7. 2012..Bullying in women may be a symptom of a broader syndrome than in men, including more prevalent impairment of impulse control and more frequent affective disorders... - Estimated cost of a factitious disorder with 6-year follow-upNicolas Hoertel
Centre Psychiatrie et Neurosciences, INSERM, U894, Universite Paris Descartes, PRES Sorbonne Paris Cité, Paris, France
Psychiatry Res 200:1077-8. 2012..We report a 6-year follow-up for a patient with Factitious Disorder who first reported neurological then psychiatric symptoms, and investigate the cost of his detected hospitalizations... 
The 3' part of the dopamine transporter gene DAT1/SLC6A3 is associated with withdrawal seizures in patients with alcohol dependenceYann Le Strat
INSERM U675, IFR02, Faculté de Médecine Xavier Bichat Université, Henri Huchard, Paris, France
Alcohol Clin Exp Res 32:27-35. 2008..We investigated whether polymorphisms within the DAT1 gene are associated with WS taking into account some of the confounding factors such as the severity of alcohol dependence...- The role of genes involved in neuroplasticity and neurogenesis in the observation of a gene-environment interaction (GxE) in schizophreniaYann Le Strat
INSERM U675, Faculte de Medecine X Bichat, Universite Paris 7, Paris, France
Curr Mol Med 9:506-18. 2009..The literature supporting this gene x environment hypothesis is reviewed, with emphasis on some molecular pathways, raising the possibility to propose more specific molecular medicine... - Subthreshold bipolar disorder in a U.S. national representative sample: prevalence, correlates and perspectives for psychiatric nosographyNicolas Hoertel
AP HP Assistance Publique Hôpitaux de Paris, Service de Psychiatrie, Hopital Louis Mourier, Colombes, France
J Affect Disord 146:338-47. 2013..This study examined and compared the prevalence and correlates of lifetime major depressive episode plus subthreshold hypomania D(m) with pure MDD, bipolar II disorder, and bipolar I disorder... - Gender differences in prevalence of substance use disorders among individuals with lifetime exposure to substances: results from a large representative sampleShaul Lev-Ran
Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
Am J Addict 22:7-13. 2013..In this study, we explored gender differences in prevalence of SUDs among individuals with lifetime exposure to substances using a single diagnostic category (abuse or dependence)... - Cannabis and Δ(9)-tetrahydrocannabinol (THC) for weight loss?Bernard Le Foll
Translational Addiction Research Laboratory, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health CAMH, Toronto, Ontario, Canada Addictions Program, CAMH, Toronto, Ontario, Canada Departments of Psychiatry, Pharmacology, Family and Community Medicine, Institute of Medical Sciences, University of Toronto, Toronto, Ontario, Canada Electronic address
Med Hypotheses 80:564-7. 2013..We therefore propose the seemingly paradoxical hypothesis that THC or a THC/cannabidiol combination drug may produce weight loss and may be a useful therapeutic for the treatment of obesity and its complications... - Blockade of dopamine d4 receptors attenuates reinstatement of extinguished nicotine-seeking behavior in ratsYijin Yan
Translational Addiction Research Laboratory, Centre for Addiction and Mental Health Addiction CAMH, University of Toronto, Toronto, ON, Canada
Neuropsychopharmacology 37:685-96. 2012....