Xavier Puechal

Summary

Affiliation: Le Mans
Country: France

Publications

  1. doi Rituximab therapy for systemic vasculitis associated with rheumatoid arthritis: Results from the AutoImmunity and Rituximab Registry
    X Puechal
    Le Mans General Hospital, Le Mans, and Cochin Hospital, Paris, France
    Arthritis Care Res (Hoboken) 64:331-9. 2012
  2. pmc CTLA-4 +49A/G and CT60 gene polymorphisms in primary Sjögren syndrome
    Jacques Eric Gottenberg
    Rhumatologie, Institut Pour la Santé et la Recherche Médicale U802, Universite Paris Sud 11, Hopital Bicetre, 78 rue du General Leclerc, Assistance Publique Hopitaux de Paris, 94275 Le Kremlin Bicetre, France
    Arthritis Res Ther 9:R24. 2007
  3. ncbi [Non antibiotic treatments of Lyme borreliosis]
    X Puechal
    Service de Rhumatologie, Centre Hospitalier du Mans, 194, avenue Rubillard, 72037 Le Mans cedex 09, France
    Med Mal Infect 37:473-8. 2007
  4. ncbi Cultivation of Tropheryma whipplei from the synovial fluid in Whipple's arthritis
    Xavier Puechal
    Le Mans General Hospital, Le Mans, France
    Arthritis Rheum 56:1713-8. 2007
  5. ncbi Antineutrophil cytoplasmic antibody-associated vasculitides
    Xavier Puechal
    Rheumatology Department, Centre Hospitalier Le Mans, 194, avenue Rubillard, 72037 Le Mans Cedex 9, France
    Joint Bone Spine 74:427-35. 2007
  6. ncbi Anti-tumour necrosis factor treatment in patients with refractory systemic vasculitis associated with rheumatoid arthritis
    X Puechal
    Department of Rheumatology, Le Mans General Hospital, Le Mans, France
    Ann Rheum Dis 67:880-4. 2008
  7. ncbi Churg-Strauss syndrome associated with omalizumab
    Xavier Puechal
    Department of Rheumatology, Le Mans General Hospital, 194 avenue Rubillard, 72000 Le Mans, France
    Eur J Intern Med 19:364-6. 2008
  8. ncbi [Whipple's disease]
    X Puechal
    Service de Rhumatologie, Centre Hospitalier du Mans, 72037 Le Mans Cedex 9, France
    Rev Med Interne 30:233-41. 2009
  9. doi What should be done in case of persistent symptoms after adequate antibiotic treatment for Lyme disease?
    Xavier Puechal
    Service de Rhumatologie, Centre Hospitalier du Mans, Le Mans, France
    Curr Probl Dermatol 37:191-9. 2009
  10. doi Tocilizumab in refractory adult Still's disease
    Xavier Puechal
    Le Mans General Hospital, Le Mans, France
    Arthritis Care Res (Hoboken) 63:155-9. 2011

Detail Information

Publications39

  1. doi Rituximab therapy for systemic vasculitis associated with rheumatoid arthritis: Results from the AutoImmunity and Rituximab Registry
    X Puechal
    Le Mans General Hospital, Le Mans, and Cochin Hospital, Paris, France
    Arthritis Care Res (Hoboken) 64:331-9. 2012
    ..We assessed the efficacy and safety of rituximab in a real-life clinical setting among patients with systemic rheumatoid vasculitis (SRV)...
  2. pmc CTLA-4 +49A/G and CT60 gene polymorphisms in primary Sjögren syndrome
    Jacques Eric Gottenberg
    Rhumatologie, Institut Pour la Santé et la Recherche Médicale U802, Universite Paris Sud 11, Hopital Bicetre, 78 rue du General Leclerc, Assistance Publique Hopitaux de Paris, 94275 Le Kremlin Bicetre, France
    Arthritis Res Ther 9:R24. 2007
    ..In fact, sampling bias may account for some contradictory results previously reported for CTLA-4 association studies in autoimmune diseases...
  3. ncbi [Non antibiotic treatments of Lyme borreliosis]
    X Puechal
    Service de Rhumatologie, Centre Hospitalier du Mans, 194, avenue Rubillard, 72037 Le Mans cedex 09, France
    Med Mal Infect 37:473-8. 2007
    ..Corticosteroids are not indicated in Lyme's disease. In post Lyme's disease syndrome, patient complaints may lead to a multidisciplinary therapeutic management and the use of neuro-psychiatric drugs...
  4. ncbi Cultivation of Tropheryma whipplei from the synovial fluid in Whipple's arthritis
    Xavier Puechal
    Le Mans General Hospital, Le Mans, France
    Arthritis Rheum 56:1713-8. 2007
    ..Antibiotic treatment was instituted in the patient, after which his symptoms remitted. These findings show for the first time that Whipple's arthritis may be, at least in some cases, a septic arthritis...
  5. ncbi Antineutrophil cytoplasmic antibody-associated vasculitides
    Xavier Puechal
    Rheumatology Department, Centre Hospitalier Le Mans, 194, avenue Rubillard, 72037 Le Mans Cedex 9, France
    Joint Bone Spine 74:427-35. 2007
    ..Biotherapies such as rituximab and TNFalpha antagonists are currently under evaluation as promising rescue agents for patients with refractory disease...
  6. ncbi Anti-tumour necrosis factor treatment in patients with refractory systemic vasculitis associated with rheumatoid arthritis
    X Puechal
    Department of Rheumatology, Le Mans General Hospital, Le Mans, France
    Ann Rheum Dis 67:880-4. 2008
    ..To assess anti-tumour necrosis factor (anti-TNF) agents in patients with refractory systemic rheumatoid vasculitis (SRV)...
  7. ncbi Churg-Strauss syndrome associated with omalizumab
    Xavier Puechal
    Department of Rheumatology, Le Mans General Hospital, 194 avenue Rubillard, 72000 Le Mans, France
    Eur J Intern Med 19:364-6. 2008
    ..Given the possible role of omalizumab in the development of this vasculitis in our patient, we recommend careful monitoring of the appearance of Churg-Strauss symptoms and rising eosinophil count in patients treated with omalizumab...
  8. ncbi [Whipple's disease]
    X Puechal
    Service de Rhumatologie, Centre Hospitalier du Mans, 72037 Le Mans Cedex 9, France
    Rev Med Interne 30:233-41. 2009
    ....
  9. doi What should be done in case of persistent symptoms after adequate antibiotic treatment for Lyme disease?
    Xavier Puechal
    Service de Rhumatologie, Centre Hospitalier du Mans, Le Mans, France
    Curr Probl Dermatol 37:191-9. 2009
    ..If a diagnosis is made for which no specific treatment can be proposed, emotional support and management of pain, fatigue and other symptoms is required...
  10. doi Tocilizumab in refractory adult Still's disease
    Xavier Puechal
    Le Mans General Hospital, Le Mans, France
    Arthritis Care Res (Hoboken) 63:155-9. 2011
    ..We report the first series of patients with ASD treated with tocilizumab (TCZ), a humanized anti-IL-6 receptor antibody...
  11. doi Mutations of the cystic fibrosis gene in patients with bronchiectasis associated with rheumatoid arthritis
    Xavier Puechal
    Center for Rare Systemic Auto immune Diseases, Department of Rheumatology, Centre Hospitalier du Mans, 194 avenue Rubillard, 72000 Le Mans, France
    Ann Rheum Dis 70:653-9. 2011
    ..DB is also associated with other diseases including rheumatoid arthritis (RA) in which the role of genetic factors in the predisposition to DB remains unclear...
  12. ncbi Whipple disease and arthritis
    X Puechal
    Service de Rhumatologie, Centre Hospitalier du Mans, Le Mans, France
    Curr Opin Rheumatol 13:74-9. 2001
    ..It may also allow earlier diagnosis, thereby preventing the development of the severe systemic and sometimes fatal forms of the disease...
  13. ncbi Thromboangiitis obliterans or Buerger's disease: challenges for the rheumatologist
    X Puechal
    Rheumatology Department, Le Mans General Hospital, Le Mans, France
    Rheumatology (Oxford) 46:192-9. 2007
    ..Blockade with antagonists of cannabinoid or endothelin receptors and the use of gene- or cell-based therapy to induce therapeutic angiogenesis have opened up new possibilities for treatment...
  14. ncbi Whipple's disease
    Xavier Puechal
    Department of Rheumatology, Centre Hospitalier du Mans, Le Mans, France
    Joint Bone Spine 69:133-40. 2002
    ..Another hope is that the diagnosis will be made earlier, before the development of potentially fatal systemic complications...
  15. ncbi Structural evaluation in the management of patients with rheumatoid arthritis: development of recommendations for clinical practice based on published evidence and expert opinion
    Laure Gossec
    Rheumatology Department, Cochin Teaching Hospital, Paris, France
    Joint Bone Spine 72:229-34. 2005
    ..To develop French evidence-based recommendations for the structural evaluation of rheumatoid arthritis (RA) in everyday practice...
  16. ncbi Cardiovascular risk and rheumatoid arthritis: clinical practice guidelines based on published evidence and expert opinion
    Thao Pham
    Service de Rhumatologie, CHU de la Conception, Marseille, France
    Joint Bone Spine 73:379-87. 2006
    ..To develop clinical practice guidelines for the evaluation and management of cardiovascular risk in patients with rheumatoid arthritis (RA), using the evidence-based approach and expert opinion...
  17. ncbi Physical examination and laboratory tests in the management of patients with rheumatoid arthritis: development of recommendations for clinical practice based on published evidence and expert opinion
    Thao Pham
    Service de Rhumatologie, CHU de la Conception, Marseille, France
    Joint Bone Spine 72:222-8. 2005
    ..To develop recommendations for the physical and laboratory-test follow-up of patients with rheumatoid arthritis (RA) seen in everyday practice, using evidence from the literature, supplemented with expert opinion when needed...
  18. doi Long-term follow-up of a randomized trial on 118 patients with polyarteritis nodosa or microscopic polyangiitis without poor-prognosis factors
    Maxime Samson
    Service de Medecine Interne, Centre National de Référence Vascularites Nécrosantes et Sclérodermie Systémique, Hopital Cochin, AP HP, Universite Paris Descartes, Inserm U 1060, Paris, France Service de Médecine Interne et Immunologie Clinique, Hopital du Bocage, Dijon, France
    Autoimmun Rev 13:197-205. 2014
    ..However, relapses remained frequent, requiring IS introduction for nearly half of the patients. To lower the frequencies of relapses and sequelae remains a challenge for FFS=0 PAN and MPA patients. ..
  19. ncbi Treatment of Churg-Strauss syndrome without poor-prognosis factors: a multicenter, prospective, randomized, open-label study of seventy-two patients
    Camillo Ribi
    Hopital Cochin, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Arthritis Rheum 58:586-94. 2008
    ....
  20. ncbi Role and modalities of information and education in the management of patients with rheumatoid arthritis: development of recommendations for clinical practice based on published evidence and expert opinion
    Bruno Fautrel
    Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Joint Bone Spine 72:163-70. 2005
    ..To develop recommendations for the information and education of patients with rheumatoid arthritis (RA) seen in everyday practice, using evidence from the literature, supplemented with expert opinion when needed...
  21. doi Azathioprine or methotrexate maintenance for ANCA-associated vasculitis
    Christian Pagnoux
    Universite Paris Descartes, Hopital Cochin, Assistance Publique Hopitaux de Paris, Paris, France
    N Engl J Med 359:2790-803. 2008
    ..However, azathioprine and methotrexate have not been compared with regard to safety and efficacy...
  22. ncbi Evaluation of two strategies (initial methotrexate monotherapy vs its combination with adalimumab) in management of early active rheumatoid arthritis: data from the GUEPARD trial
    Martin Soubrier
    Department of Rheumatology, Hopital G Montpied, 63003 Clermont Ferrand, France
    Rheumatology (Oxford) 48:1429-34. 2009
    ..To compare this strategy with an initial combination of MTX and adalimumab (ADA) given for 3 months and then adjusted based on the disease activity status...
  23. doi Long-term outcomes of 118 patients with eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome) enrolled in two prospective trials
    Maxime Samson
    Service de Medecine Interne, Centre National de Référence Vascularites Nécrosantes et Sclérodermie Systémique, Hopital Cochin, AP HP, Universite Paris Descartes, Inserm U 1060, Paris, France
    J Autoimmun 43:60-9. 2013
    ..Relapses are frequent, especially in patients with anti-myeloperoxidase antibodies and baseline eosinophilia <3000/mm(3)...
  24. ncbi Effects of hydroxychloroquine on symptomatic improvement in primary Sjögren syndrome: the JOQUER randomized clinical trial
    Jacques Eric Gottenberg
    Department of Rheumatology, Service de Rhumatologie, Hopitaux Universitaires de Strasbourg, Centre de référence national pour les maladies auto immunes systémiques rares, Universite de Strasbourg, Strasbourg, France
    JAMA 312:249-58. 2014
    ..Hydroxychloroquine is the most frequently prescribed immunosuppressant for the syndrome. However, evidence regarding its efficacy is limited...
  25. doi Prediction of response to disease modifying antirheumatic drugs in rheumatoid arthritis
    Jean Francis Maillefert
    INSERM U887, Department of Rheumatology, Hopital General, Dijon University Hospital, University of Burgundy, 3, rue du Fb Raines, 21078 Dijon, France
    Joint Bone Spine 77:558-63. 2010
    ..To investigate potential predictors of response to conventional DMARDs in RA...
  26. doi How to treat refractory arthritis in lupus?
    Mathieu Artifoni
    Center for Rare Systemic Auto immune Diseases, Department of Rheumatology, Le Mans General Hospital, 194, avenue Rubillard, 72000 Le Mans, France
    Joint Bone Spine 79:347-50. 2012
    ..As a last resort, after having weighed up the individual benefit-risk ratio, leflunomide, belimumab, rituximab or abatacept may be considered, on a case-by-case basis, and anti-TNF antibodies may be considered in exceptional cases...
  27. doi Pneumomediastinum in interstitial lung disease associated with dermatomyositis and polymyositis
    Benoit Le Goff
    Le Mans General Hospital, Le Mans, France
    Arthritis Rheum 61:108-18. 2009
    ..Spontaneous pneumomediastinum is a rare complication of dermatomyositis (DM) and polymyositis (PM). The aim of this study was to characterize this complication and determine its prognostic factors...
  28. doi TNF alpha antagonist therapy and safety monitoring
    Thao Pham
    Rheumatology Department, CHU Sainte Marguerite, Marseille, France
    Joint Bone Spine 78:15-185. 2011
    ..To develop and/or update fact sheets about TNFα antagonists treatments, in order to assist physicians in the management of patients with inflammatory joint disease...
  29. doi Pattern of demyelination occurring during anti-TNF-α therapy: a French national survey
    Raphaele Seror
    Assistance Publique Hopitaux de Paris, Biceêtre University Hospital, Department of Rheumatology, INSERM U802, France
    Rheumatology (Oxford) 52:868-74. 2013
    ..To determine the pattern of demyelinating disorders (DDs) occurring during anti-TNF-α therapy...
  30. ncbi Whipple disease revealed by lung involvement: a case report and literature review
    Geoffrey Urbanski
    Center for Rare Systemic Auto immune Diseases, Le Mans General Hospital, Le Mans, France
    Chest 141:1595-8. 2012
    ..The association of mediastinal adenopathy or pleural effusion offers additional concern. Whipple disease may be fatal in the absence of treatment, but prolonged antibiotic treatment often leads to complete remission...
  31. ncbi Recommendations of the French Society for Rheumatology. TNFalpha antagonist therapy in rheumatoid arthritis
    Bruno Fautrel
    Service de Rhumatologie, Groupe Hospitalier Pitie Salpetriere, UFR de Medecine, Universite Pierre et Marie Curie Paris VI, 83, Boulevard de l Hopital, 75651 Paris Cedex 13, France
    Joint Bone Spine 73:433-41. 2006
    ..To develop recommendations for TNFalpha-antagonist therapy in patients with rheumatoid arthritis (RA) seen in everyday practice, under the aegis of the French Society for Rheumatology...
  32. doi Tocilizumab: therapy and safety management
    Thao Pham
    Service de Rhumatologie, CHU Conception, Marseille, France
    Joint Bone Spine 77:S3-100. 2010
    ..To develop fact sheets about tocilizumab, in order to assist physicians in the management of patients with inflammatory joint disease...
  33. doi Eosinophilic granulomatosis with polyangiitis (Churg-Strauss): clinical characteristics and long-term followup of the 383 patients enrolled in the French Vasculitis Study Group cohort
    Cloé Comarmond
    Hopital Cochin, AP HP, and Universite Paris Descartes, Paris 5, Paris, France
    Arthritis Rheum 65:270-81. 2013
    ..This study was undertaken to describe the main characteristics of a larger patient cohort and their long-term outcomes...
  34. pmc Comparison of in vitro-specific blood tests with tuberculin skin test for diagnosis of latent tuberculosis before anti-TNF therapy
    Jeremie Sellam
    Service de Rhumatologie, Hopital de Bicetre, 78 rue du General Leclerc, 94275 Le Kremlin Bicetre, France
    Ann Rheum Dis 66:1610-5. 2007
    ..We aimed to investigate in vitro blood assays with TB-specific antigens (CFP-10, ESAT-6), in immune-mediated inflammatory diseases (IMID) for LTBI screening...
  35. ncbi Relapsing polychondritis
    Xavier Puechal
    Centre de référence des maladies auto immunes et systémiques rares, Hopital Cochin, Assistance Publique Hopitaux de Paris, Paris, France Institut Cochin, Inserm U1016, CNRS UMR 8104, Universite Paris Descartes, Paris, France Electronic address
    Joint Bone Spine 81:118-24. 2014
    ..Immunosuppressive agents are given to patients with severe respiratory or vascular involvement and to those with steroid-resistant or steroid-dependent disease. Methotrexate is often effective. Cyclophosphamide is used in severe forms. ..
  36. doi Whipple's disease
    Xavier Puechal
    National Referral Center for Rare Systemic Autoimmune Diseases, Hopital Cochin, Assistance Publique Hopitaux de Paris, INSERM U1016 CNRS UMR 8104, Institut Cochin, Paris Descartes University, Paris, France
    Ann Rheum Dis 72:797-803. 2013
    ....
  37. ncbi Antineutrophil cytoplasmic antibodies and the Churg-Strauss syndrome
    Régis Sablé-Fourtassou
    Hopital Cochin, Assistance Publique Hopitaux de Paris, Universite Paris 5 Rene Descartes, Paris, France
    Ann Intern Med 143:632-8. 2005
    ..Since testing for antineutrophil cytoplasmic antibodies (ANCA) became available for routine evaluation, no large homogeneous cohort of patients with the Churg-Strauss syndrome has been studied...
  38. ncbi Inefficacy of infliximab in primary Sjögren's syndrome: results of the randomized, controlled Trial of Remicade in Primary Sjögren's Syndrome (TRIPSS)
    Xavier Mariette
    Service de Rhumatologie, Hôpital de Bicêtre AP HP, and Université Paris Sud, Le Kremlin Bicetre, France
    Arthritis Rheum 50:1270-6. 2004
    ..Since tumor necrosis factor alpha (TNF alpha) could be a key element in the pathogenesis of primary SS, we conducted a multicenter, randomized, double-blind, placebo-controlled trial to evaluate the effect of infliximab in primary SS...
  39. ncbi Panton-Valentine leukocidin-producing Staphylococcus aureus infections: report of 4 French cases
    Carine Salliot
    Service de Médecine Interne et Rhumatologie et, Groupe Hospitalier Diaconesses La Croix Saint Simon, Paris, France
    Scand J Infect Dis 38:192-5. 2006
    ..These cases highlight the need to screen for PVL in patients with serious staphylococcal infections. All patients were cured. Two of them received intravenous immunoglobulins in addition to antibiotics...