Research Topics

Genomes and Genes

Xavier Le Goff


Country: France


  1. request reprint
    La Carbona S, Le Goff X. Spatial regulation of cytokinesis by the Kin1 and Pom1 kinases in fission yeast. Curr Genet. 2006;50:377-91 pubmed
    ..We show that Kin1 is required for F-actin polarization in interphase and after completion of mitosis and this function may be essential for cytokinesis in a pom1Delta background. ..
  2. Le Goff X, Chesnel F, Delalande O, Couturier A, Dreano S, Le Goff C, et al. Aggregation dynamics and identification of aggregation-prone mutants of the von Hippel-Lindau tumor suppressor protein. J Cell Sci. 2016;129:2638-50 pubmed publisher
    ..The prefoldin subunit Pac10 (the human homolog VBP-1 binds to pVHL) is required for pVHL stability. Reduction of soluble functional pVHL might be crucial in VHL-related diseases. ..