Daniel Le Bars

Summary

Country: France

Publications

  1. ncbi [Acute pain measurement in animals. Part 1]
    D Le Bars
    INSERM U 161, 2, rue d Alesia, 75014 Paris, France
    Ann Fr Anesth Reanim 20:347-65. 2001
  2. ncbi [Critical analysis of animal models of acute pain. II]
    D Le Bars
    INSERM U 161, 2, rue d Alésia 75014 Paris, France
    Ann Fr Anesth Reanim 20:452-70. 2001
  3. ncbi Animal models of nociception
    D Le Bars
    INSERM U 161, 2, rue d Alesia, 75014 Paris, France
    Pharmacol Rev 53:597-652. 2001
  4. ncbi The whole body receptive field of dorsal horn multireceptive neurones
    Daniel Le Bars
    INSERM, 2, rue d Alesia, 75014, Paris, France
    Brain Res Brain Res Rev 40:29-44. 2002
  5. pmc Psychophysics of a nociceptive test in the mouse: ambient temperature as a key factor for variation
    Ivanne Pincedé
    Team Pain, INSERM UMRS 975, CNRS UMR 7225, Paris, France
    PLoS ONE 7:e36699. 2012
  6. pmc Peripheral and central determinants of a nociceptive reaction: an approach to psychophysics in the rat
    Jean Michel Benoist
    Laboratoire de Neurophysiologie, Faculté de Médecine Pitié Salpêtrière, Paris, France
    PLoS ONE 3:e3125. 2008
  7. pmc Freezing of enkephalinergic functions by multiple noxious foci: a source of pain sensitization?
    François Cesselin
    Team Pain, INSERM UMRS 975, CNRS UMR 7225, Paris, France
    PLoS ONE 4:e6874. 2009
  8. ncbi Hyperalgesia and allodynia: peripheral mechanisms
    Anne Coutaux
    Rheumatology Department, Pitié Salpêtrière Teaching Hospital, 91, Boulevard de l Hopital, 75013 Paris, France
    Joint Bone Spine 72:359-71. 2005
  9. doi The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanism
    Frederic Adam
    Institut National de la Santé et de la Recherche Médicale INSERM U 713, Universite Pierre et Marie Curie, Faculté de Médecine Pitié Salpêtrière, 91 Boulevard de l Hopital, 75013 Paris, France
    Neuropharmacology 54:588-96. 2008
  10. ncbi Tolerance to morphine analgesia: evidence for stimulus intensity as a key factor and complete reversal by a glycine site-specific NMDA antagonist
    Frederic Adam
    Institut National de la Santé et de la Recherche Médicale INSERM U 713, 75013 Paris, France
    Neuropharmacology 51:191-202. 2006

Collaborators

  • Leon Plaghki
  • François Cesselin
  • Frederic Adam
  • Ivanne Pincedé
  • Jean Michel Benoist
  • Anne Coutaux
  • Theo Meert
  • Bernard Pollin
  • Eric Dufour
  • Kay Ballantyne
  • Francis Bonnet
  • Jean Claude Willer

Detail Information

Publications10

  1. ncbi [Acute pain measurement in animals. Part 1]
    D Le Bars
    INSERM U 161, 2, rue d Alesia, 75014 Paris, France
    Ann Fr Anesth Reanim 20:347-65. 2001
    ..To describe tests of nociception which appear in the "pre-clinical" literature...
  2. ncbi [Critical analysis of animal models of acute pain. II]
    D Le Bars
    INSERM U 161, 2, rue d Alésia 75014 Paris, France
    Ann Fr Anesth Reanim 20:452-70. 2001
    ..To analyse models of acute pain in experimental animals...
  3. ncbi Animal models of nociception
    D Le Bars
    INSERM U 161, 2, rue d Alesia, 75014 Paris, France
    Pharmacol Rev 53:597-652. 2001
    ..It is concluded that although the neural basis of the most used tests is poorly understood, their use will be more profitable if pain is considered within, rather than apart from, the body's homeostatic mechanisms...
  4. ncbi The whole body receptive field of dorsal horn multireceptive neurones
    Daniel Le Bars
    INSERM, 2, rue d Alesia, 75014, Paris, France
    Brain Res Brain Res Rev 40:29-44. 2002
    ....
  5. pmc Psychophysics of a nociceptive test in the mouse: ambient temperature as a key factor for variation
    Ivanne Pincedé
    Team Pain, INSERM UMRS 975, CNRS UMR 7225, Paris, France
    PLoS ONE 7:e36699. 2012
    ....
  6. pmc Peripheral and central determinants of a nociceptive reaction: an approach to psychophysics in the rat
    Jean Michel Benoist
    Laboratoire de Neurophysiologie, Faculté de Médecine Pitié Salpêtrière, Paris, France
    PLoS ONE 3:e3125. 2008
    ..We developed a theoretical framework, a related experimental paradigm and a model to analyze in psychophysical terms the "tail-flick" responses of rats to random variations of noxious radiant heat...
  7. pmc Freezing of enkephalinergic functions by multiple noxious foci: a source of pain sensitization?
    François Cesselin
    Team Pain, INSERM UMRS 975, CNRS UMR 7225, Paris, France
    PLoS ONE 4:e6874. 2009
    ..For example, a noxious mechanical stimulus does not alter the release of Met-enkephalin-like material (MELM) from segments of the spinal cord related to the stimulated area of the body, but does increase its release from other segments...
  8. ncbi Hyperalgesia and allodynia: peripheral mechanisms
    Anne Coutaux
    Rheumatology Department, Pitié Salpêtrière Teaching Hospital, 91, Boulevard de l Hopital, 75013 Paris, France
    Joint Bone Spine 72:359-71. 2005
    ..We will review the most extensively studied molecular and cellular mechanisms underlying these two clinical abnormalities. The role of the peripheral nervous system in progression of inflammatory joint disease to chronicity is discussed...
  9. doi The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanism
    Frederic Adam
    Institut National de la Santé et de la Recherche Médicale INSERM U 713, Universite Pierre et Marie Curie, Faculté de Médecine Pitié Salpêtrière, 91 Boulevard de l Hopital, 75013 Paris, France
    Neuropharmacology 54:588-96. 2008
    ....
  10. ncbi Tolerance to morphine analgesia: evidence for stimulus intensity as a key factor and complete reversal by a glycine site-specific NMDA antagonist
    Frederic Adam
    Institut National de la Santé et de la Recherche Médicale INSERM U 713, 75013 Paris, France
    Neuropharmacology 51:191-202. 2006
    ..These results suggest that (+)-HA966 interfered with expression of morphine tolerance, and offered an encouraging therapeutic approach for pain management in opioid abusers...