Research Topics
| Daniel Le BarsSummaryCountry: France Publications
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Detail Information
Publications
[Acute pain measurement in animals. Part 1]D Le Bars
INSERM U 161, 2, rue d Alesia, 75014 Paris, France
Ann Fr Anesth Reanim 20:347-65. 2001..To describe tests of nociception which appear in the "pre-clinical" literature...
[Critical analysis of animal models of acute pain. II]D Le Bars
INSERM U 161, 2, rue d Alésia 75014 Paris, France
Ann Fr Anesth Reanim 20:452-70. 2001..To analyse models of acute pain in experimental animals...
Animal models of nociceptionD Le Bars
INSERM U 161, 2, rue d Alesia, 75014 Paris, France
Pharmacol Rev 53:597-652. 2001..It is concluded that although the neural basis of the most used tests is poorly understood, their use will be more profitable if pain is considered within, rather than apart from, the body's homeostatic mechanisms...
The whole body receptive field of dorsal horn multireceptive neuronesDaniel Le Bars
INSERM, 2, rue d Alesia, 75014, Paris, France
Brain Res Brain Res Rev 40:29-44. 2002....
Psychophysics of a nociceptive test in the mouse: ambient temperature as a key factor for variationIvanne Pincedé
Team Pain, INSERM UMRS 975, CNRS UMR 7225, Paris, France
PLoS ONE 7:e36699. 2012....
Peripheral and central determinants of a nociceptive reaction: an approach to psychophysics in the ratJean Michel Benoist
Laboratoire de Neurophysiologie, Faculté de Médecine Pitié Salpêtrière, Paris, France
PLoS ONE 3:e3125. 2008..We developed a theoretical framework, a related experimental paradigm and a model to analyze in psychophysical terms the "tail-flick" responses of rats to random variations of noxious radiant heat...
Freezing of enkephalinergic functions by multiple noxious foci: a source of pain sensitization?François Cesselin
Team Pain, INSERM UMRS 975, CNRS UMR 7225, Paris, France
PLoS ONE 4:e6874. 2009..For example, a noxious mechanical stimulus does not alter the release of Met-enkephalin-like material (MELM) from segments of the spinal cord related to the stimulated area of the body, but does increase its release from other segments...
Hyperalgesia and allodynia: peripheral mechanismsAnne Coutaux
Rheumatology Department, , 91, , 75013 Paris, France
Joint Bone Spine 72:359-71. 2005..We will review the most extensively studied molecular and cellular mechanisms underlying these two clinical abnormalities. The role of the peripheral nervous system in progression of inflammatory joint disease to chronicity is discussed...
The glycine site-specific NMDA antagonist (+)-HA966 enhances the effect of morphine and reverses morphine tolerance via a spinal mechanismFrederic Adam
Institut National de la Santé et de la Recherche Médicale INSERM U 713, Universite Pierre et Marie Curie, Faculté de Médecine Pitié Salpêtrière, 91 Boulevard de l Hopital, 75013 Paris, France
Neuropharmacology 54:588-96. 2008....
Tolerance to morphine analgesia: evidence for stimulus intensity as a key factor and complete reversal by a glycine site-specific NMDA antagonistFrederic Adam
Institut National de la Santé et de la Recherche Médicale INSERM U 713, 75013 Paris, France
Neuropharmacology 51:191-202. 2006..These results suggest that (+)-HA966 interfered with expression of morphine tolerance, and offered an encouraging therapeutic approach for pain management in opioid abusers...
