Stephane Laurent

Summary

Country: France

Publications

  1. ncbi request reprint Day or night blood pressures to predict cardiovascular events?
    Stephane Laurent
    Department of Pharmacology and INSERM U652, Hopital Europeen Georges Pompidou, 75015 Paris, France
    Lancet 370:1192-3. 2007
  2. doi request reprint Defining vascular aging and cardiovascular risk
    Stephane Laurent
    Department of Pharmacology, Hopital Europeen Georges Pompidou, INSERM U970, Universite Paris Descartes, Paris, France
    J Hypertens 30:S3-8. 2012
  3. doi request reprint Aortic stiffness as a tissue biomarker for predicting future cardiovascular events in asymptomatic hypertensive subjects
    Stephane Laurent
    Department of Pharmacology, European Georges Pompidou Hospital, Assistance Publique Hopitaux de Paris, INSERM U970 and University Paris Descartes, France
    Ann Med 44:S93-7. 2012
  4. doi request reprint New drugs, procedures, and devices for hypertension
    Stephane Laurent
    Department of Pharmacology, European Georges Pompidou Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Lancet 380:591-600. 2012
  5. ncbi request reprint Evidence for carotid and radial artery wall subclinical lesions in renal fibromuscular dysplasia
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI U 0107, Hopital Europeen Georges Pompidou, Paris, France
    J Hypertens 21:2287-95. 2003
  6. ncbi request reprint Brachial pressure-independent reduction in carotid stiffness after long-term angiotensin-converting enzyme inhibition in diabetic hypertensives
    Anne Isabelle Tropeano
    Department of Pharmacology and INSERM U 652, Georges Pompidou European Hospital, Paris, France
    Hypertension 48:80-6. 2006
  7. ncbi request reprint Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 39:10-5. 2002
  8. ncbi request reprint Increased carotid wall stress in vascular Ehlers-Danlos syndrome
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Circulation 109:1530-5. 2004
  9. ncbi request reprint Carotid and aortic stiffness: determinants of discrepancies
    Anna Paini
    Department of Pharmacology, Hopital Europeen Georges Pompidou, INSERM U652, Universite Paris Descartes, Faculte de Medecine, Paris, France
    Hypertension 47:371-6. 2006
  10. pmc Arterial remodeling associates with CKD progression
    Marie Briet
    Department of Pharmacology and Institut National de la Santé et de la Recherche Médicale U970 PARCC, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, 20, rue Leblanc, 75015 Paris, France
    J Am Soc Nephrol 22:967-74. 2011

Detail Information

Publications66

  1. ncbi request reprint Day or night blood pressures to predict cardiovascular events?
    Stephane Laurent
    Department of Pharmacology and INSERM U652, Hopital Europeen Georges Pompidou, 75015 Paris, France
    Lancet 370:1192-3. 2007
  2. doi request reprint Defining vascular aging and cardiovascular risk
    Stephane Laurent
    Department of Pharmacology, Hopital Europeen Georges Pompidou, INSERM U970, Universite Paris Descartes, Paris, France
    J Hypertens 30:S3-8. 2012
    ..These broadly include aortic and carotid stiffening; aortic and carotid lumen dilation; endothelial dysfunction (usually measured via brachial flow-mediated dilatation); and carotid intima-media thickness...
  3. doi request reprint Aortic stiffness as a tissue biomarker for predicting future cardiovascular events in asymptomatic hypertensive subjects
    Stephane Laurent
    Department of Pharmacology, European Georges Pompidou Hospital, Assistance Publique Hopitaux de Paris, INSERM U970 and University Paris Descartes, France
    Ann Med 44:S93-7. 2012
    ....
  4. doi request reprint New drugs, procedures, and devices for hypertension
    Stephane Laurent
    Department of Pharmacology, European Georges Pompidou Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    Lancet 380:591-600. 2012
    ..The effectiveness and safety of new devices and procedures should be carefully assessed in patients with resistant hypertension, thus leading to a new era of outcome trials and evidence-based guidelines...
  5. ncbi request reprint Evidence for carotid and radial artery wall subclinical lesions in renal fibromuscular dysplasia
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI U 0107, Hopital Europeen Georges Pompidou, Paris, France
    J Hypertens 21:2287-95. 2003
    ....
  6. ncbi request reprint Brachial pressure-independent reduction in carotid stiffness after long-term angiotensin-converting enzyme inhibition in diabetic hypertensives
    Anne Isabelle Tropeano
    Department of Pharmacology and INSERM U 652, Georges Pompidou European Hospital, Paris, France
    Hypertension 48:80-6. 2006
    ..They also suggest that long-term administration of high doses (8 mg) of perindopril is required to improve carotid structure and function in hypertensive patients with type 2 diabetes...
  7. ncbi request reprint Aortic stiffness is an independent predictor of primary coronary events in hypertensive patients: a longitudinal study
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 39:10-5. 2002
    ..This study provides the first direct evidence in a longitudinal study that aortic stiffness is an independent predictor of primary coronary events in patients with essential hypertension...
  8. ncbi request reprint Increased carotid wall stress in vascular Ehlers-Danlos syndrome
    Pierre Boutouyrie
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Circulation 109:1530-5. 2004
    ..Affected patients are at risk for arterial dissection or rupture, the main cause of death. To understand the pathogenesis of the vascular lesions, we used a biomechanical approach and determined steady and pulsatile wall stress...
  9. ncbi request reprint Carotid and aortic stiffness: determinants of discrepancies
    Anna Paini
    Department of Pharmacology, Hopital Europeen Georges Pompidou, INSERM U652, Universite Paris Descartes, Faculte de Medecine, Paris, France
    Hypertension 47:371-6. 2006
    ..In these cases, the aorta stiffened more than the carotid artery with age and other cardiovascular risk factors...
  10. pmc Arterial remodeling associates with CKD progression
    Marie Briet
    Department of Pharmacology and Institut National de la Santé et de la Recherche Médicale U970 PARCC, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, 20, rue Leblanc, 75015 Paris, France
    J Am Soc Nephrol 22:967-74. 2011
    ..In conclusion, maladaptive remodeling of the carotid artery and increased pulse pressure independently associate with faster decline of renal function and progression to ESRD...
  11. doi request reprint Lowering of brachial pulse pressure in 9379 hypertensives with type 2 diabetes and reduction of cardiovascular events
    Anne Isabelle Tropeano
    Department of Pharmacology and INSERM U652, Hopital Europeen Georges Pompidou, Universite Paris Descartes, Faculte de Medecine, Paris, France
    Blood Press 17:26-33. 2008
    ..During the 9 months follow-up, the physician in charge was asked to reinforce treatment in order to lower PP, using preferentially a fixed low-dose perindopril/indapamide combination...
  12. doi request reprint Carotid plaque, arterial stiffness gradient, and remodeling in hypertension
    Hélène Beaussier
    Department of Pharmacology, Inserm U872, Hopital Europeen Georges Pompidou, Universite Paris Descartes, France
    Hypertension 52:729-36. 2008
    ..This may generate a high level of stress concentrations and fatigue, exposing the plaque to a greater risk of rupture...
  13. ncbi request reprint Endothelial function and chronic exposure to air pollution in normal male subjects
    Marie Briet
    Faculté de Médecine René Descartes, Universite Paris Descartes, INSERM, UMR872, Paris, France
    Hypertension 50:970-6. 2007
    ..Gaseous pollutants affect large artery endothelial function, whereas particulate matter exaggerates the dilatory response of small arteries to ischemia...
  14. doi request reprint Association of menopause and hormone replacement therapy with large artery remodeling
    Anne Gompel
    Universite Paris Descartes, Assistance Publique Hopitaux de Paris, Hotel Dieu, Paris, France
    Fertil Steril 96:1445-50. 2011
    ..To evaluate the remodeling of large arteries according to age at menopause, duration of menopause, and use of hormone therapy (HT)...
  15. ncbi request reprint Glucose level is a major determinant of carotid intima-media thickness in patients with hypertension and hyperglycemia
    Anne Isabelle Tropeano
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    J Hypertens 22:2153-60. 2004
    ..Carotid intima-media thickness (CIMT) is an independent predictor for cardiovascular events. High blood pressure is a major determinant of CIMT...
  16. ncbi request reprint Physiological genomics of human arteries: quantitative relationship between gene expression and arterial stiffness
    Séverine Durier
    Department of Pharmacology and INSERM EMI 107, Paris, France
    Circulation 108:1845-51. 2003
    ....
  17. ncbi request reprint Influence of pravastatin on carotid artery structure and function in dyslipidemic HIV-infected patients receiving antiretroviral therapy
    Franck Boccara
    Department of Pharmacology, Universite Paris Descartes, Faculte de Medecine, INSERM 652, Hopital Europeen Georges Pompidou, Paris, France
    AIDS 20:2395-8. 2006
    ..Age and body mass index were independent determinants of IMT of the CCA. Mean arterial pressure, age, duration of HIV infection and protease inhibitor exposure determined aortic stiffness...
  18. doi request reprint Large artery stiffening and remodeling are independently associated with all-cause mortality and cardiovascular events in chronic kidney disease
    Alexandre Karras
    Departments of Nephrology, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Paris, France
    Hypertension 60:1451-7. 2012
    ..This study shows that increased aortic stiffness and carotid internal diameter are independent predictors of mortality in patients with stages 2 to 5 chronic kidney disease and that aortic stiffness improves the prediction of the risk...
  19. doi request reprint Importance of arterial stiffness as cardiovascular risk factor for future development of new type of drugs
    Pierre Boutouyrie
    Faculté de Médecine René Descartes, Universite Paris Descartes, INSERM UMRS872 Equipe 1, 15 rue de l Ecole de Medecine, Paris F 75006, France
    Fundam Clin Pharmacol 22:241-6. 2008
    ..In parallel to this demonstration, points to be improved are the homogenization and spreading of the technique of measurement, the establishment of a reference value database...
  20. doi request reprint Long-term reduction in aortic stiffness: a 5.3-year follow-up in routine clinical practice
    Hafid Ait-Oufella
    Department of Pharmacology, European Hospital Georges Pompidou, France
    J Hypertens 28:2336-41. 2010
    ..Whether a direct blood pressure-independent reduction in aortic stiffness can occur after several years of antihypertensive treatment has never been unequivocally demonstrated...
  21. ncbi request reprint Very-low-dose combination of perindopril and indapamide: efficacy on blood pressure and target-organ damage
    Stephane Laurent
    Service de Pharmacologie, INSERM EMI 107, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    J Hypertens Suppl 21:S11-8. 2003
    ..To review the safety and efficacy of the very-low-dose combination of perindopril 2 mg and indapamide 0.625 mg (Per2/Ind0.625) in essential hypertension, in relation to blood pressure control and target-organ damage...
  22. ncbi request reprint Arterial stiffness and angiotensinogen gene in hypertensive patients and mutant mice
    Erwan Bozec
    Department of Pharmacology, Hôpital Européen Georges Pompidou and Institut National de la Santé et de la Recherche Médicale EMI 0107, Paris, France
    J Hypertens 22:1299-307. 2004
    ....
  23. ncbi request reprint Increased stiffness of the carotid wall material in patients with spontaneous cervical artery dissection
    David Calvet
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Stroke 35:2078-82. 2004
    ..The study aim was to determine the elastic properties of a cervical artery, the common carotid artery, and a distal muscular artery, the radial artery in sCAD patients...
  24. doi request reprint Age-independent association between arterial and bone remodeling in mild-to-moderate chronic kidney disease
    Marie Briet
    Universite Paris Descartes, INSERM, UMR872, Paris, France
    Nephrol Dial Transplant 25:191-7. 2010
    ..We made the hypothesis that bone disease could be associated with the carotid outward remodeling in parallel with the decline of renal function in this population...
  25. doi request reprint Accelerated arterial stiffening and gene expression profile of the aorta in patients with coronary artery disease
    Celine Fassot
    Faculty of Medicine, University Paris Descartes, Department of Pharmacology, Georges Pompidou European Hospital, Paris, France
    J Hypertens 26:747-57. 2008
    ..Arterial stiffness increases further when CRF is associated with hypertension. We hypothesized that, in patients with mild CRF, aortic gene expression profile would include genes involved in arterial calcifications and enlargement...
  26. doi request reprint Amlodipine-valsartan combination decreases central systolic blood pressure more effectively than the amlodipine-atenolol combination: the EXPLOR study
    Pierre Boutouyrie
    Department of Pharmacology, INSERM U970, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, Paris, France
    Hypertension 55:1314-22. 2010
    ..The amlodipine-valsartan combination decreased central (systolic and pulse) pressure and AIx more than the amlodipine-atenolol combination...
  27. ncbi request reprint Pulse pressure reduction and cardiovascular protection
    Stephane Laurent
    Department of Pharmacology and INSERM U652, Hopital Europeen Georges Pompidou, Paris, France
    J Hypertens Suppl 24:S13-8. 2006
    ....
  28. ncbi request reprint Recent advances in arterial stiffness and wave reflection in human hypertension
    Stephane Laurent
    Department of Pharmacology and INSERM U652, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, Universite Paris 5, 20, rue Leblanc, 75015 Paris, France
    Hypertension 49:1202-6. 2007
  29. doi request reprint Aortic stiffness is reduced beyond blood pressure lowering by short-term and long-term antihypertensive treatment: a meta-analysis of individual data in 294 patients
    Kim Thanh Ong
    Hopitaux de Paris, Hopital Europeen Georges Pompidou, France bINSERM U970, France
    J Hypertens 29:1034-42. 2011
    ..We aimed to determine whether the artery stiffness can be improved because of antihypertensive treatments independently of blood pressure lowering...
  30. doi request reprint Cardiovascular risk assessment through target organ damage: role of carotid to femoral pulse wave velocity
    Pierre Boutouyrie
    Universite Paris Descartes, Faculté de Médecine René Descartes, INSERM, UMR872, and Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Pharmacology, Paris, France
    Clin Exp Pharmacol Physiol 35:530-3. 2008
    ....
  31. doi request reprint Thromboangiitis obliterans and endothelial function
    Michel Azizi
    Universite Paris Descartes, Faculte de Medecine, Paris, France
    Eur J Clin Invest 40:518-26. 2010
    ..This study compares endothelial function and large artery stiffness between 10 TAO patients assessed during an exacerbation phase and 10 age- and sex-matched control subjects...
  32. ncbi request reprint Comparison of angiotensin II-induced blood pressure and structural changes in Fischer 344 and Wistar Kyoto rats
    Jocelyne Blanc
    Laboratory of Pharmacology, Institut National de la Sante et de la Recherche Medicale, INSERM E0107, Paris, France
    Clin Exp Pharmacol Physiol 31:466-73. 2004
    ..Angiotensin II increased BP in F344 rats, but did not exaggerate the increase in BP during the startle reaction...
  33. doi request reprint Frequent and widespread vascular abnormalities in human signal transducer and activator of transcription 3 deficiency
    Marie Olivia Chandesris
    Hematology Department, Necker Children s Hospital, Assistance Publique Hopitaux de Paris, 149 rue de Sevres, Paris, France
    Circ Cardiovasc Genet 5:25-34. 2012
    ..Although vascular abnormalities have been reported in some patients, the prevalence, characteristics, and etiology of these features have yet to be described...
  34. ncbi request reprint Rationale, design and methods of the CASHMERE study
    Tabassome Simon
    Department of Pharmacology, Paris VI University, Saint Antoine University Hospital AP HP, Paris, France
    Fundam Clin Pharmacol 18:131-8. 2004
    ..The results are expected for 2007...
  35. pmc In utero exposure to maternal diabetes impairs vascular expression of prostacyclin receptor in rat offspring
    Jean Paul Duong Van Huyen
    NSERM U872, Centre de Recherche des Cordeliers, Universite s Pierre et Marie Curie et Paris Descartes, Paris, France
    Diabetes 59:2597-602. 2010
    ..To evaluate modifications of arterial structure, gene expression, and function in our model of rats exposed to maternal diabetes...
  36. doi request reprint Differences in emotion processing in patients with essential and secondary hypertension
    Silla M Consoli
    Assistance Publique Hopitaux de Paris, Department of C L Psychiatry, European Georges Pompidou Hospital, Paris, France
    Am J Hypertens 23:515-21. 2010
    ..Alexithymia and related emotion-processing variables, however, have never been examined as a function of the type of hypertension, essential (EH) or secondary (SH)...
  37. pmc Arterial and renal consequences of partial genetic deficiency in tissue kallikrein activity in humans
    Michel Azizi
    Centre d Investigations Cliniques 9201, Assistance Publique des Hôpitaux de Paris and INSERM, Universite Paris V, Paris, France
    J Clin Invest 115:780-7. 2005
    ....
  38. doi request reprint Pharmacological modulation of arterial stiffness
    Pierre Boutouyrie
    HEGP, Assistance publique Hpitaux de Paris, INSERM U970, Universit Paris Descartes, France
    Drugs 71:1689-701. 2011
    ..While the quest continues for 'de-stiffening drugs', so far only advanced glycation endproduct cross-link breakers have shown promise...
  39. doi request reprint Sequential nephron blockade versus sequential renin-angiotensin system blockade in resistant hypertension: a prospective, randomized, open blinded endpoint study
    Guillaume Bobrie
    Assistance Publique, Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    J Hypertens 30:1656-64. 2012
    ..To compare two drug regimens to treat resistant hypertension...
  40. ncbi request reprint Expert consensus document on arterial stiffness: methodological issues and clinical applications
    Stephane Laurent
    Department of Pharmacology and Hôpital Européen Georges Pompidou, Universite Paris Descartes, Faculte de Medecine, Assistance Publique Hopitaux de Paris, INSERM U652, 20 rue Leblanc, 75015 Paris, France
    Eur Heart J 27:2588-605. 2006
    ....
  41. ncbi request reprint Multiaxial mechanical characteristics of carotid plaque: analysis by multiarray echotracking system
    Anna Paini
    Department of Pharmacology, Universite Paris Descartes, Faculte de Medecine, INSERM U652, Hopital Europeen Georges Pompidou, Paris, France
    Stroke 38:117-23. 2007
    ..Carotid plaque rupture depends on the various types of mechanical stresses. Our objective was to determine the multiaxial mechanical characteristics of atherosclerotic plaque and adjacent segment of the common carotid artery...
  42. doi request reprint Effect of celiprolol on prevention of cardiovascular events in vascular Ehlers-Danlos syndrome: a prospective randomised, open, blinded-endpoints trial
    Kim Thanh Ong
    Assistance Publique, Hopitaux de Paris, Hopital Europeen Georges Pompidou, Paris, France
    Lancet 376:1476-84. 2010
    ..Our aim was to assess the ability of celiprolol, a β(1)-adrenoceptor antagonist with a β(2)-adrenoceptor agonist action, to prevent arterial dissections and ruptures in vascular Ehlers-Danlos syndrome...
  43. ncbi request reprint Angiotensinogen gene M235T polymorphism and reduction in wall thickness in response to antihypertensive treatment
    Erwan Bozec
    Department of Pharmacology, INSERM EMI 0107, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Clin Sci (Lond) 105:637-44. 2003
    ..In conclusion, these data suggest that the angiotensinogen TT genotype at position 235 is a genetic marker for early carotid atherosclerosis in a hypertensive population and its regression under antihypertensive treatment...
  44. ncbi request reprint Arterial remodeling and stiffness in patients with pseudoxanthoma elasticum
    Dominique P Germain
    Service de Pharmacologie et INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Arterioscler Thromb Vasc Biol 23:836-41. 2003
    ..The aim of the present study was to determine large artery phenotype in patients with pseudoxanthoma elasticum (PXE), a genetic disease characterized by proteoglycan accumulation and fragmented elastic fibers in connective tissues...
  45. ncbi request reprint Aortic stiffness is an independent predictor of fatal stroke in essential hypertension
    Stephane Laurent
    Department of Pharmacology and INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Stroke 34:1203-6. 2003
    ..The influence of arterial stiffness on the occurrence of stroke has never been demonstrated. Our aim was to establish the relationship between aortic stiffness and stroke death in hypertensive patients...
  46. doi request reprint Mechanical and structural characteristics of carotid plaques by combined analysis with echotracking system and MR imaging
    Hélène Beaussier
    Department of Pharmacology and INSERM U970, Hopital Europeen Georges Pompidou, Paris, France
    JACC Cardiovasc Imaging 4:468-77. 2011
    ..The purpose of this study was to correlate the arterial mechanics of carotid atherosclerotic plaques assessed from echotracking with their composition by high-resolution magnetic resonance imaging (HR-MRI)...
  47. ncbi request reprint Arterial stiffness in arterial hypertension
    Stephane Laurent
    Department of Pharmacology and INSERM U 652, Hopital Europeen Georges Pompidou, Paris, France
    Curr Hypertens Rep 8:179-80. 2006
  48. ncbi request reprint Arterial stiffness and stroke in hypertension: therapeutic implications for stroke prevention
    Stephane Laurent
    Department of Pharmacology and INSERM EMI 107, Hopital Europeen Georges Pompidou, 20 rue Leblanc, Paris, 75015, France
    CNS Drugs 19:1-11. 2005
    ....
  49. doi request reprint Aortic, carotid and femoral stiffness: how do they relate? Towards reference values
    Stephane Laurent
    Department of Pharmacology and Inserm U872, European Hospital Georges Pompidou, Paris, France
    J Hypertens 26:1305-6. 2008
  50. ncbi request reprint [Drugs and arterial stiffness in hypertensive patients]
    Stephane Laurent
    INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Drugs 63:1-8. 2003
    ..They should be performed in patients at high cardiovascular risk, on a large scale and a long-term basis, and include all-cause and cardiovascular mortality and cardiovascular morbidity'...
  51. ncbi request reprint [Predictors of cardiovascular mortality and morbidity in hypertension]
    Stephane Laurent
    Service de Pharmacologie et INSERM EMI 0107, Hopital Europeen Georges Pompidou, Paris, France
    Curr Med Res Opin 21:S7-11. 2005
    ....
  52. ncbi request reprint Structural and genetic bases of arterial stiffness
    Stephane Laurent
    Department of Pharmacology and INSERM EMI 107, Hopital Europeen Georges Pompidou, Paris, France
    Hypertension 45:1050-5. 2005
    ..These data provide strong evidence that arterial stiffness is affected by the amount and density of stiff wall material and the spatial organization of that material...
  53. ncbi request reprint Alpha1-antitrypsin gene polymorphisms are not associated with renal arterial fibromuscular dysplasia
    Jérôme Perdu
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Department of Medical Genetics, Paris, France
    J Hypertens 24:705-10. 2006
    ..Case reports have associated alpha1-antitrypsin deficiency and FMD. The aim of this study was to test the implication of the alpha1-antitrypsin (AAT) gene in a large cohort of patients with renal FMD...
  54. pmc Large-vessel correlates of cerebral small-vessel disease
    Marion Brisset
    INSERM U708, Neuroepidemiology, Paris, France
    Neurology 80:662-9. 2013
    ..Our aim was to investigate the relationship of carotid structure and function with MRI markers of cerebral ischemic small-vessel disease...
  55. doi request reprint Ultrastructural scoring of skin biopsies for diagnosis of vascular Ehlers-Danlos syndrome
    Kim Thanh Ong
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, INSERM U970, Universite Paris Descartes, Paris, France
    Virchows Arch 460:637-49. 2012
    ..Presence of two or more signs (either abnormal fibroblast, presence of lysosomes in the fibroblast or abnormal basal lamina) is very evocative of vEDS...
  56. doi request reprint Coronary artery disease. Are β-blockers truly helpful in patients with CAD?
    Nicolas Danchin
    Department of Cardiology, Hopital Europeen Georges Pompidou, 20 rue Leblanc, Paris, France
    Nat Rev Cardiol 10:11-2. 2013
    ..The role of β-blockers for secondary prevention in these patients should be reconsidered...
  57. ncbi request reprint Pathophysiology of hypertension in the elderly
    Stephane Laurent
    Department of Pharmacology, EMI U 0107 Inserm, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Am J Geriatr Cardiol 11:34-9. 2002
    ..In this elderly population, further research is needed concerning the pathophysiology, epidemiology, and pharmacology of hypertension...
  58. ncbi request reprint Clinical applications of arterial stiffness: therapeutics and pharmacology
    Stephane Laurent
    Department of Pharmacology, Hĵpital Européen Georges Pompidou, Paris, France
    Am J Hypertens 15:453-8. 2002
    ..Directions for future therapeutic trials are suggested...
  59. ncbi request reprint Evidence for benefits of perindopril in hypertension and its complications
    Stephane Laurent
    Department of Pharmacology and INSERM U652, Hopital Europeen Georges Pompidou, 20 rue Leblanc, 75015 Paris, France
    Am J Hypertens 18:155S-162S. 2005
    ....
  60. ncbi request reprint [Large artery and left ventricular remodelling in Fabry disease.]
    Pierre Boutouyrie
    Universite Paris Descartes, Faculte de Medecine, Département de Pharmacologie et Inserm U 652, Hopital Europeen Georges Pompidou, Assistance Publique Hopitaux de Paris, 20 rue Leblanc, 75015 Paris, France
    Med Sci (Paris) 21:30-2. 2005
    ..These results show that tissues of the cardiovascular system tend to be oversensitive to trophic signals in patients with Fabry disease. double dagger...
  61. ncbi request reprint Contrasting circadian rhythms of blood pressure among inbred rat strains: recognition of dipper and non-dipper patterns
    Alexandra Basset
    INSERM EMI 0107, Laboratoire de Biomécanique et Pharmacologie de la Paroi Artérielle, Paris, France
    J Hypertens 22:727-37. 2004
    ....
  62. ncbi request reprint Physicians' degree of motivation regarding their perception of hypertension, and blood pressure control
    Silla M Consoli
    Department of Medical Psychology and Consultation Liaison Psychiatry, Georges Pompidou European Hospital, Assistance Publique Hopitaux de Paris, Paris, France
    J Hypertens 28:1330-9. 2010
    ..Despite clear international guidelines, the achievement of blood pressure (BP) control is still disappointing...
  63. doi request reprint Reference intervals for common carotid intima-media thickness measured with echotracking: relation with risk factors
    Lian Engelen
    Department of Pharmacology and INSERM U970, Hopital Europeen Georges Pompidou, Paris, France
    Eur Heart J 34:2368-80. 2013
    ..We therefore aimed to establish reference intervals of CCIMT, obtained using the probably most accurate method at present (i.e. echotracking), to help interpretation of these measures...
  64. doi request reprint Heart rate variability and functional outcome in ischemic stroke: a multiparameter approach
    Beata Graff
    Department of Hypertension and Diabetology, Hypertension Unit bDepartment of Neurology for Adults, Medical University of Gdansk, Gdansk, Poland
    J Hypertens 31:1629-36. 2013
    ..For better understanding of derived HRV data and to avoid methodological bias we simultaneously recorded and analyzed heart rate, blood pressure and respiratory rate...
  65. ncbi request reprint Arterial stiffness and pulse pressure in CKD and ESRD
    Marie Briet
    Department of Pharmacology and INSERM Institut National de la Santéet de la Recherche Médicale U970 PARCC, Hopital Europeen Georges Pompidou, Paris, France
    Kidney Int 82:388-400. 2012
    ....
  66. doi request reprint Arterial stiffness is increased in patients with inflammatory bowel disease
    Luca Zanoli
    Department of Internal Medicine, University of Catania, Catania, Italy
    J Hypertens 30:1775-81. 2012
    ..In these patients, the chronic low-grade inflammation may predispose to vascular remodelling and arterial stiffening. We aimed at studying arterial stiffness in IBD patients...