Louis Lambrechts

Summary

Country: France

Publications

  1. pmc Environmental influence on the genetic basis of mosquito resistance to malaria parasites
    Louis Lambrechts
    CNRS UMR 7103, Université Pierre et Marie Curie Paris, Parasitologie Evolutive, CC 237, CP52, 7 quai St Bernard, 75252 Paris Cedex 05, France
    Proc Biol Sci 273:1501-6. 2006
  2. ncbi request reprint Genetic correlation between melanization and antibacterial immune responses in a natural population of the malaria vector Anopheles gambiae
    Louis Lambrechts
    Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre and Marie Curie, CC237, 7 quai St Bernard, 75252 Paris Cedex 05, France
    Evolution 58:2377-81. 2004
  3. pmc Host genotype by parasite genotype interactions underlying the resistance of anopheline mosquitoes to Plasmodium falciparum
    Louis Lambrechts
    Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Université P, and M, Curie, CC 237, 7 quai St Bernard, 75252 Paris Cedex 05, France
    Malar J 4:3. 2005
  4. ncbi request reprint Coevolutionary interactions between host and parasite genotypes
    Louis Lambrechts
    Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre et Marie Curie, CC 237, 7 quai St Bernard, 75252 Paris Cedex 05, France
    Trends Parasitol 22:12-6. 2006
  5. ncbi request reprint Effect of infection by Plasmodium falciparum on the melanization immune response of Anopheles gambiae
    Louis Lambrechts
    Laboratoire de Parasitologie Evolutive, Centre National de la Recherche Scientifique Université Pierre et Marie Curie, Paris, France
    Am J Trop Med Hyg 76:475-80. 2007
  6. ncbi request reprint Anopheles gambiae immune responses to Sephadex beads: involvement of anti-Plasmodium factors in regulating melanization
    Emma Warr
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205 2179, USA
    Insect Biochem Mol Biol 36:769-78. 2006
  7. pmc Increased melanizing activity in Anopheles gambiae does not affect development of Plasmodium falciparum
    Kristin Michel
    Faculty of Natural Sciences, Section of Infection and Immunity, Imperial College London, London SW7 2AZ, United Kingdom
    Proc Natl Acad Sci U S A 103:16858-63. 2006
  8. pmc A major genetic locus controlling natural Plasmodium falciparum infection is shared by East and West African Anopheles gambiae
    Michelle M Riehle
    Microbial and Plant Genomics Institute and Department of Microbiology, University of Minnesota, St Paul, MN 55108, USA
    Malar J 6:87. 2007
  9. doi request reprint Can transgenic mosquitoes afford the fitness cost?
    Louis Lambrechts
    Department of Entomology, University of California, One Shields Avenue, Davis, CA 95616, USA
    Trends Parasitol 24:4-7. 2008

Detail Information

Publications9

  1. pmc Environmental influence on the genetic basis of mosquito resistance to malaria parasites
    Louis Lambrechts
    CNRS UMR 7103, Université Pierre et Marie Curie Paris, Parasitologie Evolutive, CC 237, CP52, 7 quai St Bernard, 75252 Paris Cedex 05, France
    Proc Biol Sci 273:1501-6. 2006
    ..e. the lines responded similarly to environmental variation. Overall, these results indicate that environmental variation can significantly reduce the importance of genes in determining the resistance of mosquitoes to malaria infection...
  2. ncbi request reprint Genetic correlation between melanization and antibacterial immune responses in a natural population of the malaria vector Anopheles gambiae
    Louis Lambrechts
    Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre and Marie Curie, CC237, 7 quai St Bernard, 75252 Paris Cedex 05, France
    Evolution 58:2377-81. 2004
    ..Thus, our data do not support the idea of a trade-off among different outcomes of the invertebrate immune system, but rather that some families are overall immunologically superior to others...
  3. pmc Host genotype by parasite genotype interactions underlying the resistance of anopheline mosquitoes to Plasmodium falciparum
    Louis Lambrechts
    Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Université P, and M, Curie, CC 237, 7 quai St Bernard, 75252 Paris Cedex 05, France
    Malar J 4:3. 2005
    ..In such systems, certain hosts are resistant to one subset of the parasite's genotypes, while other hosts are resistant to a different subset...
  4. ncbi request reprint Coevolutionary interactions between host and parasite genotypes
    Louis Lambrechts
    Laboratoire de Parasitologie Evolutive, CNRS UMR 7103, Universite Pierre et Marie Curie, CC 237, 7 quai St Bernard, 75252 Paris Cedex 05, France
    Trends Parasitol 22:12-6. 2006
    ..Moreover, not only the traits of the infection but also the genetic correlations among these and other traits that determine fitness might be controlled by interactions between host and parasite genotypes...
  5. ncbi request reprint Effect of infection by Plasmodium falciparum on the melanization immune response of Anopheles gambiae
    Louis Lambrechts
    Laboratoire de Parasitologie Evolutive, Centre National de la Recherche Scientifique Université Pierre et Marie Curie, Paris, France
    Am J Trop Med Hyg 76:475-80. 2007
    ..falciparum relies on immune evasion rather than immuno-suppression to avoid being melanized and confirms that natural malaria transmission systems differ from laboratory models of mosquito-Plasmodium interactions...
  6. ncbi request reprint Anopheles gambiae immune responses to Sephadex beads: involvement of anti-Plasmodium factors in regulating melanization
    Emma Warr
    W Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, 615 N Wolfe Street, Baltimore, MD 21205 2179, USA
    Insect Biochem Mol Biol 36:769-78. 2006
    ....
  7. pmc Increased melanizing activity in Anopheles gambiae does not affect development of Plasmodium falciparum
    Kristin Michel
    Faculty of Natural Sciences, Section of Infection and Immunity, Imperial College London, London SW7 2AZ, United Kingdom
    Proc Natl Acad Sci U S A 103:16858-63. 2006
    ..falciparum. This study suggests immune evasion strategies of the human malaria parasite and emphasizes the need to study mosquito innate immune responses toward the pathogens they transmit in natural vector-parasite combinations...
  8. pmc A major genetic locus controlling natural Plasmodium falciparum infection is shared by East and West African Anopheles gambiae
    Michelle M Riehle
    Microbial and Plant Genomics Institute and Department of Microbiology, University of Minnesota, St Paul, MN 55108, USA
    Malar J 6:87. 2007
    ..An important question is whether genetic variation with respect to Plasmodium-resistance exists across Africa, and if so whether the same or multiple geographically distinct resistance mechanisms are responsible for the trait...
  9. doi request reprint Can transgenic mosquitoes afford the fitness cost?
    Louis Lambrechts
    Department of Entomology, University of California, One Shields Avenue, Davis, CA 95616, USA
    Trends Parasitol 24:4-7. 2008
    ..Indeed, for the spread of a resistance transgene in a natural situation, the transgene's fitness cost and the efficacy of the gene drive will be more crucial than any evolutionary advantage...