Research Topics
Genomes and Genes | Nadine LaguetteSummaryCountry: France Publications
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Publications
How SAMHD1 changes our view of viral restrictionNadine Laguette
Laboratoire de Virologie Moleculaire, Institut de Genetique Humaine, CNRS UPR 1142, 141 rue de la Cardonille, 34296 Montpellier Cedex 5, France
Trends Immunol 33:26-33. 2012....
SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by VpxNadine Laguette
Institut de Genetique Humaine, Laboratoire de Virologie Moleculaire, CNRS UPR1142, Montpellier 34000, France
Nature 474:654-7. 2011..Our results demonstrate that SAMHD1 is an antiretroviral protein expressed in cells of the myeloid lineage that inhibits an early step of the viral life cycle...
SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cellsBenjamin Descours
Institut de Genetique Humaine, CNRS UPR1142, Laboratoires de Virologie Moléculaire, Montpellier, France
Retrovirology 9:87. 2012..Quiescent CD4+ T lymphocytes are highly refractory to HIV-1 infection due to a block at reverse transcription...
Evolutionary and functional analyses of the interaction between the myeloid restriction factor SAMHD1 and the lentiviral Vpx proteinNadine Laguette
Institut de Genetique Humaine, Centre National de la Recherche Scientifique, Unité Propre de Recherche 1142, Laboratoires de Virologie Moléculaire, 34000 Montpellier, France
Cell Host Microbe 11:205-17. 2012..The distinct evolutionary signature of SAMHD1 sheds light on the development of its antiviral specificity...
HIV-1 Tat assembles a multifunctional transcription elongation complex and stably associates with the 7SK snRNPBijan Sobhian
Laboratoire de Virologie Moleculaire, Institut de Genetique Humaine, CNRS UPR1142, Montpellier, France
Mol Cell 38:439-51. 2010....
