M L Lacombe

Summary

Country: France

Publications

  1. ncbi request reprint The human Nm23/nucleoside diphosphate kinases
    M L Lacombe
    INSERM U402, Faculte de Medecine Saint Antoine, Paris, France
    J Bioenerg Biomembr 32:247-58. 2000
  2. ncbi request reprint The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase
    L Milon
    INSERM U402, Faculte de Medecine Saint Antoine, 27 rue Chaligny, 75012 Paris, France
    J Biol Chem 275:14264-72. 2000
  3. ncbi request reprint A new human nm23 homologue (nm23-H5) specifically expressed in testis germinal cells
    A Munier
    INSERM U402, Faculte de Medecine Saint Antoine, Paris, France
    FEBS Lett 434:289-94. 1998
  4. ncbi request reprint nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13
    L Milon
    INSERM U 402, Faculte de Medecine Saint Antoine, Paris, France
    Hum Genet 99:550-7. 1997
  5. ncbi request reprint Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit
    V P Pinon
    INSERM U402, CHU Saint Antoine, Paris, France
    Exp Cell Res 246:355-67. 1999
  6. ncbi request reprint Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development
    V Wallet
    Unite de Biochimie Cellulaire, Institut Pasteur, Paris, France
    J Natl Cancer Inst 82:1199-202. 1990
  7. ncbi request reprint X-ray structure of human nucleoside diphosphate kinase B complexed with GDP at 2 A resolution
    S Morera
    Laboratoire de Biologie Structurale, UMR 9920 CNRS Université Paris Sud, Gif sur Yvette, France
    Structure 3:1307-14. 1995
  8. ncbi request reprint A novel serine/threonine-specific protein phosphotransferase activity of Nm23/nucleoside-diphosphate kinase
    M Engel
    Institut fur Humangenetik, Universitat des Saarlandes, Homburg, Germany
    Eur J Biochem 234:200-7. 1995
  9. ncbi request reprint Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene
    M Erent
    Institut de Biochimie et Génétique Cellulaires UMR 5095, Centre National de la Recherche Scientifique et Université de Bordeaux 2, France
    Eur J Biochem 268:1972-81. 2001
  10. ncbi request reprint Functional cloning of a nucleoside diphosphate kinase from Dictyostelium discoideum
    M L Lacombe
    Unite de Biochimie Cellulaire, Institut Pasteur, Paris, France
    J Biol Chem 265:10012-8. 1990

Collaborators

  • P Meyer
  • J Vassy
  • M Veron
  • G Millot
  • A Munier
  • L Milon
  • J Capeau
  • M Erent
  • I Lascu
  • V P Pinon
  • J Janin
  • G Raschella
  • M Konrad
  • J Cherfils
  • A Giartosio
  • P Tissier
  • F Agou
  • C Sarger
  • P Gonin
  • A Karlsson
  • M Chiadmi
  • M Engel
  • M Johansson
  • S Morera
  • F Calvo
  • G Linares-Cruz
  • G Guellaen
  • G Gyapay
  • C Feral
  • M F Rousseau-Merck
  • T Seib
  • C Welter
  • Y Xu
  • G Lebras
  • S Dooley
  • B Theisinger
  • V Wallet
  • O Barzu
  • R Mutzel
  • B Wurster
  • H Troll

Detail Information

Publications10

  1. ncbi request reprint The human Nm23/nucleoside diphosphate kinases
    M L Lacombe
    INSERM U402, Faculte de Medecine Saint Antoine, Paris, France
    J Bioenerg Biomembr 32:247-58. 2000
    ..This suggests that Nm23/NDP kinases possess different, but specific, functions within the cell, depending on their localization. The roles of NDP kinases in metabolic pathways and nucleic acid synthesis are discussed...
  2. ncbi request reprint The human nm23-H4 gene product is a mitochondrial nucleoside diphosphate kinase
    L Milon
    INSERM U402, Faculte de Medecine Saint Antoine, 27 rue Chaligny, 75012 Paris, France
    J Biol Chem 275:14264-72. 2000
    ..Submitochondrial fractionation indicates that Nm23-H4 is associated with mitochondrial membranes, possibly to the contact sites between the outer and inner membranes...
  3. ncbi request reprint A new human nm23 homologue (nm23-H5) specifically expressed in testis germinal cells
    A Munier
    INSERM U402, Faculte de Medecine Saint Antoine, Paris, France
    FEBS Lett 434:289-94. 1998
    ..However, under usual assay conditions, Nm23-H5 expressed in Escherichia coli did not exhibit NDP kinase activity. These results suggest that Nm23-H5 is specifically involved in early stages of spermatogenesis...
  4. ncbi request reprint nm23-H4, a new member of the family of human nm23/nucleoside diphosphate kinase genes localised on chromosome 16p13
    L Milon
    INSERM U 402, Faculte de Medecine Saint Antoine, Paris, France
    Hum Genet 99:550-7. 1997
    ..Nm23-H4 naturally possesses the Pro-Ser substitution equivalent to the K-pn mutation (P97S) of Drosophila...
  5. ncbi request reprint Cytoskeletal association of the A and B nucleoside diphosphate kinases of interphasic but not mitotic human carcinoma cell lines: specific nuclear localization of the B subunit
    V P Pinon
    INSERM U402, CHU Saint Antoine, Paris, France
    Exp Cell Res 246:355-67. 1999
    ..Their altered localization in dividing cells suggests colocalization with yet unidentified structures which are not intermediate filament aggregates...
  6. ncbi request reprint Dictyostelium nucleoside diphosphate kinase highly homologous to Nm23 and Awd proteins involved in mammalian tumor metastasis and Drosophila development
    V Wallet
    Unite de Biochimie Cellulaire, Institut Pasteur, Paris, France
    J Natl Cancer Inst 82:1199-202. 1990
    ..Our results point to an unexpected role of NDP kinase in development, growth control, and oncogenic transformation...
  7. ncbi request reprint X-ray structure of human nucleoside diphosphate kinase B complexed with GDP at 2 A resolution
    S Morera
    Laboratoire de Biologie Structurale, UMR 9920 CNRS Université Paris Sud, Gif sur Yvette, France
    Structure 3:1307-14. 1995
    ..It activates transcription of the c-myc oncogene independently of its catalytic function, by binding to its promoter DNA. How do the two functions coexist?..
  8. ncbi request reprint A novel serine/threonine-specific protein phosphotransferase activity of Nm23/nucleoside-diphosphate kinase
    M Engel
    Institut fur Humangenetik, Universitat des Saarlandes, Homburg, Germany
    Eur J Biochem 234:200-7. 1995
    ..Furthermore, the novel Nm23 function is compared with an apparently similar protein phosphotransferase activity which was observed previously with partially purified NDPK from different plant species...
  9. ncbi request reprint Structural and catalytic properties and homology modelling of the human nucleoside diphosphate kinase C, product of the DRnm23 gene
    M Erent
    Institut de Biochimie et Génétique Cellulaires UMR 5095, Centre National de la Recherche Scientifique et Université de Bordeaux 2, France
    Eur J Biochem 268:1972-81. 2001
    ..The overall structure of the two enzymes appears to be identical because NDP kinase CDelta readily formed mixed hexamers with NDP kinase A. It is possible that mixed hexamers can be observed in vivo...
  10. ncbi request reprint Functional cloning of a nucleoside diphosphate kinase from Dictyostelium discoideum
    M L Lacombe
    Unite de Biochimie Cellulaire, Institut Pasteur, Paris, France
    J Biol Chem 265:10012-8. 1990
    ..Although NDP kinases from a great variety of sources have been characterized, the primary structure of the D. discoideum NDP kinase is the first reported for an enzyme of eukaryotic origin...