Research Topics
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Publications
Laurentixanthones A and B, antimicrobial xanthones from Vismia laurentiiJean Robert Nguemeving
Department of Organic Chemistry, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon
Phytochemistry 67:1341-6. 2006..The structures of compounds were established by means of spectroscopic methods. Furthermore, the compounds were screened for antimicrobial activities in vitro...
Diospyrone, crassiflorone and plumbagin: three antimycobacterial and antigonorrhoeal naphthoquinones from two Diospyros sppVictor Kuete
Department of Biochemistry, University of Dschang, P O BOX 67, Dschang, Cameroon
Int J Antimicrob Agents 34:322-5. 2009..The overall results of this work provide evidence that the studied plant extracts (diospyrone, crassiflorone and plumbagin) might be potential sources of new antimicrobial drugs against tuberculosis and gonorrhoea...
Antibacterial constituents of three Cameroonian medicinal plants: Garcinia nobilis, Oricia suaveolens and Balsamocitrus camerunensisHugues Fouotsa
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon
BMC Complement Altern Med 13:81. 2013....
Antibacterial activities of the extracts, fractions and compounds from Dioscorea bulbiferaVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, P, O, Box 67, Dschang, Cameroon
BMC Complement Altern Med 12:228. 2012....
Antimicrobial activity of selected South African medicinal plantsTrine R H Nielsen
Department of Medicinal Chemistry Faculty of Pharmaceutical Sciences, University of Copenhagen, Copenhagen, Denmark
BMC Complement Altern Med 12:74. 2012..In the present study, twelve South African medicinal plants were selected and tested for their antimicrobial activities against eight microbial species belonging to fungi, Mycobacteria, Gram-positive and Gram-negative bacteria...
Cytotoxicity, anti-angiogenic, apoptotic effects and transcript profiling of a naturally occurring naphthyl butenone, guieranone AVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon
Cell Div 7:16. 2012..abstract:..
Isobavachalcone: an overviewVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon
Chin J Integr Med 18:543-7. 2012..The compound was isolated from plant families, mostly Moraceae and Fabaceae. This review brings out together the knowledge on IBC, and can serve as the start point for future research and valorization accomplishments...
Potential of Cameroonian plants and derived products against microbial infections: a reviewVictor Kuete
Department of Biochemistry, University of Dschang, Dschang, Cameroon
Planta Med 76:1479-91. 2010..However, much work is still to be done to standardize methods and cut-off points for describing the antimicrobial activity, and on the study of the mechanisms of action...
Toxicological evaluation of the hydroethanol extract of Tabernaemontana crassa (Apocynaceae) stem barkVictor Kuete
Department of Biochemistry, University of Dschang, Dschang, Cameroon
J Ethnopharmacol 130:470-6. 2010..Tabernaemontana crassa Benth. is a medicinal plant widely used in Cameroon folk medicine to treat a variety of affections. This study was aimed at evaluating its toxicological profile...
Evaluation of flavonoids from Dorstenia barteri for their antimycobacterial, antigonorrheal and anti-reverse transcriptase activitiesV Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, P O BOX 67, Dschang, Cameroon
Acta Trop 116:100-4. 2010..barteri could be potential sources of new antimicrobial drug against tuberculosis (TB), gonorrhea and probably the acquired immunodeficiency syndrome...
Antimicrobial activity of the methanolic extract and compounds from the stem bark of Drypetes tessmannianaVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, P O BOX 67, Dschang, Cameroon
Chin J Integr Med 16:337-43. 2010....
Antioxidant, antitumor and antimicrobial activities of the crude extract and compounds of the root bark of Allanblackia floribundaVictor Kuete
Department of Biochemistry, University of Dschang, Cameroon
Pharm Biol 49:57-65. 2011..Allanblackia floribunda Oliver (Guttiferae) is an African medicinal plant used traditionally to treat a variety of ailments...
Antimicrobial activities of the methanol extract, fractions and compounds from Ficus polita Vahl. (Moraceae)Victor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
BMC Complement Altern Med 11:6. 2011..polita (FPR), as well as that of its fractions (FPR1-5) and two of the eight isolated compounds, namely euphol-3-O-cinnamate (1) and (E)-3,5,4'-trihydroxy-stilbene-3,5-O-β-D-diglucopyranoside (8)...
Antimicrobial activities of the CH2Cl2-CH3OH (1:1) extracts and compounds from the roots and fruits of Pycnanthus angolensis (Myristicaceae)Victor Kuete
Department of Biochemistry, University of Dschang, Dschang, Cameroon
Nat Prod Res 25:432-43. 2011..The overall results provided evidence that P. angolensis and some of its components might be potential sources of antimicrobial drugs against tuberculosis, bacterial and fungal diseases...
Antimicrobial activities of the methanol extract and compounds from Artocarpus communis (Moraceae)Victor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
BMC Complement Altern Med 11:42. 2011....
Antimicrobial activity of the methanolic extract and compounds from Morus mesozygia stem barkV Kuete
Department of Biochemistry, University of Dschang, P O BOX 67, Dschang, Cameroon
J Ethnopharmacol 124:551-5. 2009....
Antimicrobial activity of the crude extract, fractions and compounds from stem bark of Ficus ovata (Moraceae)Victor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, B P 67 Dschang, Cameroon
J Ethnopharmacol 124:556-61. 2009....
Antimicrobial activity of the methanolic extracts and compounds from Vismia laurentii De Wild (Guttiferae)Victor Kuete
Department of Biochemistry, Faculty of Science, University of Yaounde I, P O Box 812 Yaounde, Cameroon
J Ethnopharmacol 109:372-9. 2007..These results provide promising baseline information for the potential use of these crude extracts as well as some of the isolated compounds in the treatment of bacterial and fungal infections...
Antimicrobial activity of the methanolic extract and of the chemical constituents isolated from Newbouldia laevisV Kuete
Department of Biochemistry, Yaounde University I, Yaounde, Cameroon
Pharmazie 62:552-6. 2007..The results indicate a promising basis for the use of Newbouldia laevis and some of its active principles in the treatment of infectious diseases...
Antimicrobial activity of the methanolic extract, fractions and compounds from the stem bark of Irvingia gabonensis (Ixonanthaceae)Victor Kuete
Department of Biochemistry, Faculty of Science, University of Yaounde I, BP 812, Yaounde, Cameroon
J Ethnopharmacol 114:54-60. 2007..22 microg/ml (4.26 microM) for compounds was recorded with compound 6 on Neisseria gonorrhoeae. The obtained results confirmed the use of Irvingia gabonensis in the treatment of bacterial and fungal infections...
Antimicrobial activity of the crude extracts and compounds from Ficus chlamydocarpa and Ficus cordata (Moraceae)V Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, P O BOX 67, Dschang, Cameroon
J Ethnopharmacol 120:17-24. 2008..FCB was found to be more active than FCR on most of the tested organisms. The results provided evidence that the studied plants extract, as well as some of the isolated compounds might be potential sources of new antimicrobial drug...
Antitumor, antioxidant and antimicrobial activities of Bersama engleriana (Melianthaceae)Victor Kuete
Department of Biochemistry, Faculty of Science, University of Yaounde I, BP 812 Yaounde, Cameroon
J Ethnopharmacol 115:494-501. 2008....
Antimicrobial activity of the methanolic extracts and compounds from Treculia obovoidea (Moraceae)Victor Kuete
Department of Biochemistry, Faculty of Science, University of Yaounde I, P O Box 812, Yaounde, Cameroon
J Ethnopharmacol 112:531-6. 2007..The obtained results provide promising baseline information for the potential use of these crude extract as well as some of the isolated compounds in the treatment of bacterial and fungal infections...
Antimicrobial activity of the methanolic extract, fractions and four flavonoids from the twigs of Dorstenia angusticornis Engl. (Moraceae)Victor Kuete
Department of Biochemistry, Faculty of Science, University of Yaounde I, P O Box 812 Yaounde, Cameroon
J Ethnopharmacol 112:271-7. 2007..1100 and OECD 401guideline showed that DAT was not toxic. Our findings provide a possible basis for the potential use of twigs from Dorstenia angusticornis in the treatment of infectious diseases...
Cytotoxicity and mode of action of four naturally occuring flavonoids from the genus Dorstenia: gancaonin Q, 4-hydroxylonchocarpin, 6-prenylapigenin, and 6,8-diprenyleriodictyolVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
Planta Med 77:1984-9. 2011..1 % inhibition). The results of the present work provide evidence of the cytotoxic potential of the four studied flavonoids and supportive data for further investigations...
Antimicrobial activity of the crude extracts and five flavonoids from the twigs of Dorstenia barteri (Moraceae)Armelle Tsafack Mbaveng
Department of Biochemistry, Faculty of Science, University of Yaounde I, B P 812 Yaoundé, Cameroon
J Ethnopharmacol 116:483-9. 2008..The overall results provide promising baseline information for the potential use of the crude extracts from DBT as well as some of the isolated compounds in the treatment of bacterial and fungal infections...
Antimicrobial activities of the methanol extract and compounds from the twigs of Dorstenia mannii (Moraceae)Armelle T Mbaveng
Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
BMC Complement Altern Med 12:83. 2012....
Antibacterial and antibiotic-potentiation activities of the methanol extract of some cameroonian spices against Gram-negative multi-drug resistant phenotypesIgor K Voukeng
Department of Biochemistry, Faculty of Science, University of Dschang, P, O, Box 67, Dschang, Cameroon, Africa
BMC Res Notes 5:299. 2012....
Evaluation of four Cameroonian medicinal plants for anticancer, antigonorrheal and antireverse transcriptase activitiesArmelle T Mbaveng
Department of Biochemistry, Faculty of Science, University of Yaounde I, Cameroon
Environ Toxicol Pharmacol 32:162-7. 2011..Finally, the results of the present study provide baseline information for the use of B. engleriana, C. lusitanica, G. tessmanii, V. paradoxa...
Antibacterial activity of selected Cameroonian dietary spices ethno-medically used against strains of Mycobacterium tuberculosisEmmanuel Mouafo Tekwu
Laboratory for Tuberculosis Research, Biotechnology Centre, University of Yaounde I, Yaounde, PO Box 812 Yaounde, Cameroon
J Ethnopharmacol 142:374-82. 2012..Spices are largely used ethno-medically across Africa...
Pycnanthulignenes A-D, antimicrobial cyclolignene derivatives from the roots of Pycnanthus angolensisEric C N Nono
Department of Organic Chemistry, University of Yaounde I, P O Box 812 Yaounde, Cameroon
J Nat Prod 73:213-6. 2010..The structures of these compounds were established using spectroscopic methods. Compounds 1 and 3 showed significant antimicrobial activities against a panel of drug-resistant pathogens...
Two new antimicrobial dimeric compounds: febrifuquinone, a vismione-anthraquinone coupled pigment and adamabianthrone, from two Psorospermum speciesMaurice Tsaffack
Department of Organic Chemistry, TWAS Research Unit, Yaounde University I, Cameroon
Chem Pharm Bull (Tokyo) 57:1113-8. 2009..Their structures were determined using modern spectroscopic methods including one and two dimensional-NMR techniques as well as MS. Compounds 1 and 2 showed significant antimicrobial activities against a wide range of bacteria and fungi...
A new fatty aldol ester from the aerial part of Mimosa invisa (Mimosaceae)Frédéric Nana
Department of Organic Chemistry, University of Yaounde I, P O Box 812, Yaounde, Cameroon
Nat Prod Res 26:1831-6. 2012..The antimicrobial activities of the crude extract and compounds 1 and 9 were investigated against seven microbial species. The natural products showed moderate activities compared to that of the crude extract...
Antibacterial activity and cytotoxicity of selected Egyptian medicinal plantsVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon
Planta Med 78:193-9. 2012..hermonis and V. vinifera in the treatment of bacterial infections and jaeschkeanadiol p-hydroxybenzoate in the control of cancer diseases...
Efflux pumps are involved in the defense of Gram-negative bacteria against the natural products isobavachalcone and diospyroneVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon
Antimicrob Agents Chemother 54:1749-52. 2010..The overall results indicate that isobavachalcone and diospyrone could be candidates for the development of new drugs against MDR strains and that their use in combination with efflux pump inhibitors reinforces their activity...
Coumestan glycosides from the stem bark of Cylicodiscus gabunensisKazie Nchancho
Department of Organic Chemistry, Faculty of Science, University of Yaoundi I, P O Box 812, Cameroon
Nat Prod Commun 4:931-4. 2009..Coumestoside C exhibited antimicrobial activity against Proteus vulgaris...
Cytotoxicity and modes of action of four naturally occuring benzophenones: 2,2',5,6'-Tetrahydroxybenzophenone, guttiferone E, isogarcinol and isoxanthochymolVictor Kuete
Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, 55128 Mainz, Germany Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
Phytomedicine 20:528-36. 2013....
Anticancer activities of six selected natural compounds of some Cameroonian medicinal plantsVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon
PLoS ONE 6:e21762. 2011..Compounds 1 and 2 were then tested in several other cancer cells and their possible mode of action were investigated...
Cytotoxicity and antimicrobial activity of the methanol extract and compounds from Polygonum limbatumJean P Dzoyem
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon
Planta Med 78:787-92. 2012..The overall results of the present study provided baseline information for the possible use of Polygonum limbatum as well as some of the isolated compounds for the control of cancer diseases and mostly leukemia...
Antibacterial activities of selected Cameroonian spices and their synergistic effects with antibiotics against multidrug-resistant phenotypesAimé G Fankam
Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
BMC Complement Altern Med 11:104. 2011..The present study was designed to evaluate the antibacterial activities of the methanol extracts of eleven Cameroonian spices on a panel of twenty nine Gram negative bacteria including MDR strains...
Newbouldiaquinone A: A naphthoquinone-anthraquinone ether coupled pigment, as a potential antimicrobial and antimalarial agent from Newbouldia laevisKenneth Oben Eyong
Department of Organic Chemistry, Yaounde University I, P.O. Box 812, Yaounde, Cameroon
Phytochemistry 67:605-9. 2006..Its antimicrobial activity against a wide range of microorganisms was 13- and 24-fold more active against Candida gabrata and Enterobacter aerogens than the reference antibiotics nystatin and gentamycin...
Antibacterial Activities of Selected Cameroonian Plants and Their Synergistic Effects with Antibiotics against Bacteria Expressing MDR PhenotypesStephen T Lacmata
Department of Biochemistry, Faculty of Science, University of Dschang, Dschang, Cameroon
Evid Based Complement Alternat Med 2012:623723. 2012..nitida, G. lucida and G. kola could be used alone or in association with common antibiotics in the fight of bacterial infections involving MDR strains...
Antimicrobial activity of the methanolic extract from the stem bark of Tridesmostemon omphalocarpoides (Sapotaceae)V Kuete
Department of Biochemistry, , Faculty of Science, P.O. Box 812, Yaound, Cameroon
J Ethnopharmacol 104:5-11. 2006..This was found to be non-toxic to the inbred Wistar rats treated per os. The results of this study suggested that the stem bark of this plant could be safely used in the treatment of some infectious diseases...
Antibacterial activities of the methanol extracts of ten Cameroonian vegetables against Gram-negative multidrug-resistant bacteriaJaures A K Noumedem
Department of Biochemistry, Faculty of Science, University of Dschang, P O BOX 67, Dschang, Cameroon
BMC Complement Altern Med 13:26. 2013..This study was designed at evaluating the antibacterial activities of the methanol extracts of ten Cameroonian vegetables against a panel of twenty nine Gram negative bacteria including multi-drug resistant (MDR) strains...
Cytotoxicity of some Cameroonian spices and selected medicinal plant extractsVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, Cameroon
J Ethnopharmacol 134:803-12. 2011..Several medicinal plants and spices are used traditionally to treat cancers in Cameroon...
Pharmacogenomics of Cameroonian traditional herbal medicine for cancer therapyVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang, P O BOX 67, Dschang, Cameroon
J Ethnopharmacol 137:752-66. 2011..Ethnopharmacological usages such as immune and skin disorders, inflammatory, and others chould be considered when selecting plants used to treat cancer, since these reflect disease states bearing relevance to cancer or a cancer symptoms...
Cytotoxic and antimicrobial activity of selected Cameroonian edible plantsJean Paul Dzoyem
Department of Biochemistry Faculty of Science, University of Dschang, Dschang, Cameroon
BMC Complement Altern Med 13:78. 2013....
Antidiarrheal activity of extracts and compound from Trilepisium madagascariense stem barkGerald Ngo Teke
Laboratory of Microbiology and Antimicrobial Substances, Faculty of Sciences, University of Dschang, PO Box 67 Dschang, Cameroon
Indian J Pharmacol 42:157-63. 2010..The present study was performed to evaluate the preventive and curative antidiarrheal effects of the methanol extract, fractions and compound from the stem bark of Trilepisium madagascariense in rats...
Cameroonian medicinal plants: pharmacology and derived natural productsVictor Kuete
Department of Biochemistry, Faculty of Science, University of Dschang Dschang, Cameroon
Front Pharmacol 1:123. 2010..However, much work is still to be done to standardize methodologies and to study the mechanisms of action of isolated natural products...
Xanthones from Garcinia smeathmannii (Oliver) and their antimicrobial activityJustin Komguem
Department of Organic Chemistry, Faculty of Science, , P.O. Box 812, Yaound, Cameroon
Phytochemistry 66:1713-7. 2005..1,3,5-Trihydroxyxanthone and 1,5-dihydroxyxanthone were also obtained. The compounds showed only modest activity against a range of bacteria and yeasts...
