Research Topics
| Anne Sophie KorganowSummaryCountry: France Publications
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Publications
Peripheral B cell abnormalities in patients with systemic lupus erythematosus in quiescent phase: decreased memory B cells and membrane CD19 expressionAnne Sophie Korganow
CNRS UPR9021, Université de Strasbourg UDS, Hopitaux Universitaires de Strasbourg, Strasbourg, France
J Autoimmun 34:426-34. 2010..It is not associated with an evident gene expression alteration and in vitro stimulation restores a control phenotype. These findings suggest certain mechanisms of lupus development...
Auto-reactive B cells in transgenic miceJean Louis Pasquali
Laboratory of Immunopathology, INSERM U 737 and Université Louis Pasteur, Hopitaux Universitaires de Strasbourg, 67 091 Strasbourg, France
J Autoimmun 29:250-6. 2007....
Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunityJean Nicolas Schickel
CNRS UPR9021, IBMC, Strasbourg, France
EMBO Mol Med 4:1261-75. 2012....
B cell signature during inactive systemic lupus is heterogeneous: toward a biological dissection of lupusJean Claude Garaud
CNRS UPR 9021, Institut de Biologie Moleculaire et Cellulaire, Strasbourg, France
PLoS ONE 6:e23900. 2011..Thus, this microarray analysis of B cells during quiescent lupus suggests that, despite a similar lupus phenotype, different biological roads can lead to human lupus...
Influenza virus-induced type I interferon leads to polyclonal B-cell activation but does not break down B-cell toleranceAnne Woods
INSERM U737, Universite Louis Pasteur, Hopitaux Universitaires de Strasbourg, Strasbourg, France
J Virol 81:12525-34. 2007..Taken together, these experiments show that virus-induced acute type I interferon production is not able by itself to break down B-cell tolerance in both normal and autoimmune genetic backgrounds...
Autoimmunity in common variable immunodeficiency: correlation with lymphocyte phenotype in the French DEFI studyJulien Boileau
Department of Clinical Immunology and Internal Medicine, Hôpitaux Universitaires de Strasbourg et Université de Strasbourg, CNRS UPR9021, Strasbourg, France
J Autoimmun 36:25-32. 2011..In view of recent findings on CD21(low) B cells in CVID and RA, we suggest that both a restricted subset of B cells and a T cell help are required for a breakdown of B cell tolerance against membrane auto antigens in CVID...
Macroautophagy is deregulated in murine and human lupus T lymphocytesFrédéric Gros
CNRS, Immunologie et Chimie Thérapeutiques, Institut de Biologie Moleculaire et Cellulaire, Strasbourg, France
Autophagy 8:1113-23. 2012..These results suggest that autophagy could regulate the survival of autoreactive T cell during lupus, and could thus lead to design new therapeutic options for lupus...
The antiphospholipid syndromeJean Louis Pasquali
Clinical Immunology Department, Nouvel Hopital Civil, Hopitaux Universitaires de Strasbourg, Université de Strasbourg and INSERM, U737, 67091 Strasbourg, France
Best Pract Res Clin Rheumatol 22:831-45. 2008....
