Research Topics
Species | Eric KonofalSummaryCountry: France Publications
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Publications
Restless legs syndrome and attention-deficit/hyperactivity disorderEric Konofal
Ann Neurol 58:341-2; author reply 342. 2005- Restless legs syndrome and attention-deficit/hyperactivity disorder: a review of the literatureSamuele Cortese
Service de Psychopathologie de l Enfant et de l Adolescent, Hopital Robert Debre, Paris, France
Sleep 28:1007-13. 2005.... - Effects of iron supplementation on attention deficit hyperactivity disorder in childrenEric Konofal
Hopital Robert Debre, Service de Psychopathologie de l Enfant et de l Adolescent, Paris, France
Pediatr Neurol 38:20-6. 2008..Iron therapy was well tolerated and effectiveness is comparable to stimulants... 
Attention-deficit/hyperactivity disorder, Tourette's syndrome, and restless legs syndrome: the iron hypothesisSamuele Cortese
APHP, Child and Adolescent Psychopathology Unit, Robert Debre Hospital, Paris VII University, Paris, France
Med Hypotheses 70:1128-32. 2008..In conclusion, the iron hypothesis may help us progress in the understanding of pathophysiological links between ADHD, RLS, and TS, suggesting that iron supplementation might be effective for all these three impairing conditions...- Attention-deficit/hyperactivity disorder (ADHD) and obesity: a systematic review of the literatureSamuele Cortese
AP HP, Child and Adolescent Psychopathology Unit, Robert Debre Hospital, Paris VII University, Paris, France
Crit Rev Food Sci Nutr 48:524-37. 2008..This might allow a more appropriate clinical management and, ultimately, a better quality of life for patients with both obesity and ADHD... - Sleep and ADHDEric Konofal
Pediatric Sleep Disorders Center, Robert Debre Hospital, Paris, France
Sleep Med 11:652-8. 2010..We also discuss some possible avenues for future research in the field... - [Restless legs syndrome in children and adolescents]Eric Konofal
Service de Psychopathologie de l Enfant et de l Adolescent, centre pédiatrique des pathologies du sommeil, Hopital Robert Debre, 75019 Paris, France
Presse Med 39:592-7. 2010..A relationship with Attention Deficit Disorder Hyperactivity is common, and treatment options claim to be studied, and moreover in both conditions... - Two early descriptions of restless legs syndrome and periodic leg movements by Boissier de Sauvages (1763) and Gilles de la Tourette (1898)Eric Konofal
Unité des pathologies du sommeil and Pierre and Marie Curie University, Hopital Pitie Salpetriere, APHP, Paris, France
Sleep Med 10:586-91. 2009..quot; Their descriptions confirm that the clinical features of RLS were previously described in French literature in the 18th century... - Impact of restless legs syndrome and iron deficiency on attention-deficit/hyperactivity disorder in childrenEric Konofal
Service de Psychopathologie de l Enfant et de l Adolescent, Hopital Robert Debre, 48 Boulevard Serurier, 75019 Paris, France
Sleep Med 8:711-5. 2007..To date, the impact of iron deficiency, RLS and familial history of RLS on ADHD severity has been scarcely examined in children. These issues are addressed in the present study... - Periodic leg movements and REM sleep without atonia in Parkinson's disease with camptocormiaSophie Lavault
Unité des pathologies du sommeil, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Paris, France
Mov Disord 24:2419-23. 2009..Lesions causing this axial dystonia may spare the sleep systems but affect the control of movements during sleep... - Sleep disturbances and serum ferritin levels in children with attention-deficit/hyperactivity disorderSamuele Cortese
AP HP, Child and Adolescent Psychopathology Unit, Robert Debre Hospital, Paris VII University, Paris, France
Eur Child Adolesc Psychiatry 18:393-9. 2009..The aim of this study was to assess the association between serum ferritin levels and parent reports of sleep disturbances in a sample of children with ADHD... - Effectiveness of iron supplementation in a young child with attention-deficit/hyperactivity disorderEric Konofal
Service de Psychopathologie de l Enfant et de l Adolescent, Hopital Robert Debre, Paris, France
Pediatrics 116:e732-4. 2005..The Conners' Parent and Teacher Rating Scale raw total scores decreased to 19 and 13, respectively. This is the first report of the effectiveness of iron supplementation in a young child with attention-deficit/hyperactivity disorder... - REM sleep behavior disorder and REM sleep without atonia in patients with progressive supranuclear palsyIsabelle Arnulf
Fédération des Pathologies du Sommeil and Upres EA 2397, Paris, France
Sleep 28:349-54. 2005.... - Does excessive daytime sleepiness contribute to explaining the association between obesity and ADHD symptoms?Samuele Cortese
AP HP, Child and Adolescent Psychopathology Unit, Robert Debre Hospital, Paris VII University, Paris, France
Med Hypotheses 70:12-6. 2008..Research on the role of EDS might allow advancements in this field, suggesting a more effective management and, ultimately, a better quality of life of patients with both obesity and ADHD... - Brain iron levels in attention-deficit/hyperactivity disorder: a pilot MRI studySamuele Cortese
Child and Adolescent Psychopathology Unit, Robert Debre Hospital, Paris VII University, Paris, France
World J Biol Psychiatry 13:223-31. 2012..The secondary aim was to assess the correlation between serum ferritin and BI levels... - Sleep in children with attention-deficit/hyperactivity disorder: meta-analysis of subjective and objective studiesSamuele Cortese
Robert Debre Hospital, Paris, France
J Am Acad Child Adolesc Psychiatry 48:894-908. 2009..To perform a meta-analysis of subjective (i.e., based on questionnaires) and objective (i.e., using polysomnography or actigraphy) studies comparing sleep in children with attention-deficit/hyperactivity disorder (ADHD) versus controls... - Sleep and alertness in children with attention-deficit/hyperactivity disorder: a systematic review of the literatureSamuele Cortese
AP HP Hôpital Robert Debré, Service de Psychopathologie de l Enfant et de l Adolescent, Paris, France
Sleep 29:504-11. 2006..To review evidence on sleep and alertness in children with attention-deficit/hyperactivity disorder (ADHD) controlling for potential confounding factors... - Restless legs syndrome, rapid eye movement sleep behavior disorder, and hypersomnia in patients with two parkin mutationsNadege Limousin
Unité des Pathologies du sommeil and UMR 975, Universite Paris 6, Hopital Pitie Salpetriere, Assistance Publique Hôpitaux de, Paris, France
Mov Disord 24:1970-6. 2009.... - Ropinirole in a child with attention-deficit hyperactivity disorder and restless legs syndromeEric Konofal
Service de Psychopathologie de l'Enfant et de l'Adolescent, , Paris, France
Pediatr Neurol 32:350-1. 2005..Treatment with the dopamine agonist ropinirole resulted in a significant improvement in both his attention-deficit hyperactivity disorder symptoms and sleep problems... - Effectiveness of ropinirole for RLS and depressive symptoms in an 11-year-old girlSamuele Cortese
APHP, Child and Adolescent Psychopathol Unit, Robert Debré Hosp, Paris VII Univ, Paris, France Child Neuropsychiatry Unit, G B Rossi Hosp, Dept of Mother Child and Biol Genetics, Verona Univ, Verona, Italy
Sleep Med 10:259-61. 2009..The PLM index did not remarkably change. We strongly recommend double blind, randomized, controlled studies to gain insight into the effective treatment strategies for RLS and depression when they coexist in children... - Iron deficiency in children with attention-deficit/hyperactivity disorderEric Konofal
Service de Psychopathologie de l Enfant et de l Adolescent, Hopital Robert Debre, Paris, France
Arch Pediatr Adolesc Med 158:1113-5. 2004..Iron deficiency causes abnormal dopaminergic neurotransmission and may contribute to the physiopathology of attention-deficit/hyperactivity disorder (ADHD)... - Prevalence of attention deficit hyperactivity disorder and associated features among children in FranceMichel Lecendreux
Robert Debre Hospital, Paris VII University, France
J Atten Disord 15:516-24. 2011..Earlier studies point to the prevalence of attention deficit hyperactivity disorder (ADHD) to be similar around the world. There is, however, a wide variety in estimates. The prevalence of ADHD in youth has never been examined in France... - Restless legs syndrome triggered by heart surgerySamuele Cortese
AP HP, Service de Psychopathologie de l Enfant et de l Adolescent, Hopital Robert Debre, Paris, France
Pediatr Neurol 35:223-6. 2006..If confirmed by further evidence, this patient suggests the need to carefully monitor for restless legs syndrome symptoms in young surgical patients who present with a familial history of restless legs syndrome... - Alertness and feeding behaviors in ADHD: does the hypocretin/orexin system play a role?Samuele Cortese
APHP, Child and Adolescent Psychopathology Unit, Robert Debre Hospital, Paris VII University, 48 Bd Serurier, 75019 Paris, France
Med Hypotheses 71:770-5. 2008..All this body of research would provide a tremendous opportunity to improve the quality of life of patients with ADHD by means of pathophysiologically oriented treatment... - Rapid eye movement sleep disturbances in Huntington diseaseIsabelle Arnulf
Pathologies du Sommeil, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris AP HP, and U106, University Pierre and Marie Curie, Paris Cedex 13, France
Arch Neurol 65:482-8. 2008..Sleep disorders including insomnia, movements during sleep, and daytime sleepiness are common but poorly studied in Huntington disease (HD)... - Dopamine dysregulation syndrome in a patient with restless legs syndromeSmaranda Leu-Semenescu
Pitie Salpetriere Hospital, AP HP, Paris, France
Sleep Med 10:494-6. 2009..Later, he had no impulse disorders (no gambling, hypersexuality, excessive shopping), which occur with dopamine agonists, suggesting that levodopa abuse and impulse disorders can result through different mechanisms... - Stages 1-2 non-rapid eye movement sleep behavior disorder associated with dementia: a new parasomnia?Isabelle Arnulf
Fédération des pathologies du sommeil, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Paris, France
Mov Disord 20:1223-8. 2005..This newly described stages 1--2 non-REM sleep behavior disorder suggests that central motor pattern generators were disinhibited during non-REM sleep... - Parent reports of sleep/alertness problems and ADHD symptoms in a sample of obese adolescentsSamuele Cortese
Child Neuropsychiatry Unit, Department of Mother Child and Biology Genetics, G B Rossi Hospital, Verona University, Verona, Italy
J Psychosom Res 63:587-90. 2007..The aim of this study was to assess the relationship between parent reports of sleep/alertness problems and ADHD traits in a clinical sample of obese adolescents, controlling for symptoms of anxiety/depression... - Family-based association study of the restless legs syndrome loci 2 and 3 in a European populationDavid Kemlink
Institute of Human Genetics, GSF National Research Center for Environment and Health, Munich, Germany
Mov Disord 22:207-12. 2007..0077, respectively). These results represent the first confirmation of these loci in a mixed European population. Variable results observed in families of different ethnic groups further corroborate the genetic complexity of RLS... - Effect of genetically caused excess of brain gamma-hydroxybutyric acid and GABA on sleepIsabelle Arnulf
Fédération des pathologies du sommeil, Hopital Pitie Salpetriere
Sleep 28:418-24. 2005..Exogenous gamma-hydroxybutyrate (GHB) increases slow-wave sleep and reduces daytime sleepiness and cataplexy in patients with primary narcolepsy... - ADHD and insomniaSamuele Cortese
J Am Acad Child Adolesc Psychiatry 45:384-5. 2006 
Lead and neuroprotection by iron in ADHDEric Konofal
Environ Health Perspect 115:A398-9; author reply A399. 2007- [Sleep and vigilance in hyperactive children]Michel Lecendreux
Rev Prat 52:2002-4. 2002..Excessive nocturnal motricity could be the expression of a monoaminergic dysfunctioning previously reported in ADHD and could lead to new therapeutic gateways as well as hypovigilance...