Isabelle Kone-Paut

Summary

Country: France

Publications

  1. ncbi request reprint Lupus in adolescence
    I Kone-Paut
    Department of Pediatrics and Pediatric Rheumatology, Hopital de Bicetre, Le Kremlin Bicetre, France
    Lupus 16:606-12. 2007
  2. ncbi request reprint [The child with fever in pyrins time]
    I Kone-Paut
    Service de Pediatrie Generale, Rhumatologie, Hematologie, CHU de Bicetre, APHP, 78, rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Arch Pediatr 14:652-5. 2007
  3. doi request reprint Registries in rheumatological and musculoskeletal conditions. Paediatric Behçet's disease: an international cohort study of 110 patients. One-year follow-up data
    Isabelle Kone-Paut
    Department of Paediatric Rheumatology, CEREMAI, Bicetre University Hospital, Paris SUD University of Medicine, Le Kremlin Bicetre, France
    Rheumatology (Oxford) 50:184-8. 2011
  4. ncbi request reprint [Fibromyalgia]
    I Kone-Paut
    Service de Pediatrie Generale, Hématologie et Rhumatologie Pédiatrique, Hopital de Bicetre, 78, rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Arch Pediatr 13:548-50. 2006
  5. ncbi request reprint [Back pain in children]
    I Kone-Paut
    Service de Pediatrie Generale, Hématologie et Rhumatologie Pédiatrique, Hopital de Bicetre, APHP, 78, rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Arch Pediatr 13:761-3. 2006
  6. doi request reprint Targeting interleukin-1β in CAPS (cryopyrin-associated periodic) syndromes: what did we learn?
    Isabelle Kone-Paut
    Division of Pediatric Rheumatology and Division of Pediatrics, CEREMAI, University of Paris Sud, Bicetre Hospital, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre, Paris, France
    Autoimmun Rev 12:77-80. 2012
  7. pmc Autoinflammatory gene mutations in Behçet's disease
    I Kone-Paut
    Department of Pediatrics and Pediatric Rheumatology, Hopital de Bicetre, 78 rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Ann Rheum Dis 66:832-4. 2007
  8. doi request reprint The clinical spectrum of 94 patients carrying a single mutated MEFV allele
    Isabelle Kone-Paut
    Department of Paediatrics and Paediatric Rheumatology, Hopital de Bicetre, National Reference Centre for Auto inflammatory Disorders, Le Kremlin Bicetre, France
    Rheumatology (Oxford) 48:840-2. 2009
  9. pmc Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-blind placebo-controlled randomized withdrawal study
    Isabelle Kone-Paut
    Centre de Référence des Maladies Autoinflammatoires, Hôpital Kremlin Bicêtre, Paris University of Medicine, Le Kremlin Bicetre, Paris, France
    Arthritis Res Ther 13:R202. 2011
  10. pmc Joint contractures in the absence of inflammation may indicate mucopolysaccharidosis
    Rolando Cimaz
    Ospedale Meyer Reumatologia, Firenze, Italy
    Pediatr Rheumatol Online J 7:18. 2009

Collaborators

Detail Information

Publications28

  1. ncbi request reprint Lupus in adolescence
    I Kone-Paut
    Department of Pediatrics and Pediatric Rheumatology, Hopital de Bicetre, Le Kremlin Bicetre, France
    Lupus 16:606-12. 2007
    ..Patients' quality of life and psychosocial development have also to be taken into account, as well as the organization of a successful transition from paediatric to adult care...
  2. ncbi request reprint [The child with fever in pyrins time]
    I Kone-Paut
    Service de Pediatrie Generale, Rhumatologie, Hematologie, CHU de Bicetre, APHP, 78, rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Arch Pediatr 14:652-5. 2007
  3. doi request reprint Registries in rheumatological and musculoskeletal conditions. Paediatric Behçet's disease: an international cohort study of 110 patients. One-year follow-up data
    Isabelle Kone-Paut
    Department of Paediatric Rheumatology, CEREMAI, Bicetre University Hospital, Paris SUD University of Medicine, Le Kremlin Bicetre, France
    Rheumatology (Oxford) 50:184-8. 2011
    ..To set-up an international cohort of patients suspected with Behçet's disease (BD). The cohort is aimed at defining an algorithm for definition of the disease in children...
  4. ncbi request reprint [Fibromyalgia]
    I Kone-Paut
    Service de Pediatrie Generale, Hématologie et Rhumatologie Pédiatrique, Hopital de Bicetre, 78, rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Arch Pediatr 13:548-50. 2006
  5. ncbi request reprint [Back pain in children]
    I Kone-Paut
    Service de Pediatrie Generale, Hématologie et Rhumatologie Pédiatrique, Hopital de Bicetre, APHP, 78, rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Arch Pediatr 13:761-3. 2006
  6. doi request reprint Targeting interleukin-1β in CAPS (cryopyrin-associated periodic) syndromes: what did we learn?
    Isabelle Kone-Paut
    Division of Pediatric Rheumatology and Division of Pediatrics, CEREMAI, University of Paris Sud, Bicetre Hospital, Assistance Publique Hopitaux de Paris, Le Kremlin Bicetre, Paris, France
    Autoimmun Rev 12:77-80. 2012
    ..More studies evaluating the efficacy and safety of anti-IL-1 drugs given in patients before 2 years of age are warranted, since it is believed that the earliest treatment could avoid secondary CAPS complications to develop...
  7. pmc Autoinflammatory gene mutations in Behçet's disease
    I Kone-Paut
    Department of Pediatrics and Pediatric Rheumatology, Hopital de Bicetre, 78 rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Ann Rheum Dis 66:832-4. 2007
    ..In addition, mutations in genes for familial Mediterranean fever and tumour necrosis factor receptor-associated periodic syndrome have been reported to have increased in patients with BD...
  8. doi request reprint The clinical spectrum of 94 patients carrying a single mutated MEFV allele
    Isabelle Kone-Paut
    Department of Paediatrics and Paediatric Rheumatology, Hopital de Bicetre, National Reference Centre for Auto inflammatory Disorders, Le Kremlin Bicetre, France
    Rheumatology (Oxford) 48:840-2. 2009
    ..To assess the clinical characteristics of patients living in France and carrying a single MEFV mutation...
  9. pmc Sustained remission of symptoms and improved health-related quality of life in patients with cryopyrin-associated periodic syndrome treated with canakinumab: results of a double-blind placebo-controlled randomized withdrawal study
    Isabelle Kone-Paut
    Centre de Référence des Maladies Autoinflammatoires, Hôpital Kremlin Bicêtre, Paris University of Medicine, Le Kremlin Bicetre, Paris, France
    Arthritis Res Ther 13:R202. 2011
    ..To assess the effect of canakinumab, a fully human anti-interleukin-1β antibody, on symptoms and health-related quality of life (HRQoL) in patients with cryopyrin-associated periodic syndrome (CAPS)...
  10. pmc Joint contractures in the absence of inflammation may indicate mucopolysaccharidosis
    Rolando Cimaz
    Ospedale Meyer Reumatologia, Firenze, Italy
    Pediatr Rheumatol Online J 7:18. 2009
    ..Patients with attenuated MPS disease often experience diagnostic delays. Enzyme replacement therapy is now commercially available for MPS I (laronidase), MPS II (idursulfase), and MPS VI (galsulfase)...
  11. doi request reprint Validation of the new paediatric criteria for the diagnosis of familial Mediterranean fever: data from a mixed population of 100 children from the French reference centre for auto-inflammatory disorders
    Anuela Kondi
    Department of Pediatrics and Pediatric Rheumatology, National Reference Center for Auto Inflammatory Disorders, Bicêtre University Paris Sud Hospital, Le Kremlin Bicetre, France
    Rheumatology (Oxford) 49:2200-3. 2010
    ..We aimed to validate the new paediatric criteria for diagnosis of FMF in a mixed population of 100 French patients...
  12. pmc A preliminary score for the assessment of disease activity in hereditary recurrent fevers: results from the AIDAI (Auto-Inflammatory Diseases Activity Index) Consensus Conference
    Maryam Piram
    Department of Pediatrics and Pediatric Rheumatology, National Reference Center for Auto Inflammatory Disorders, Bicetre University Hospital, Paris XI University, Le Kremlin Bicetre, France
    Ann Rheum Dis 70:309-14. 2011
    ....
  13. ncbi request reprint Efficacy of interleukin-1-targeting drugs in mevalonate kinase deficiency
    Caroline Galeotti
    Department of Pediatrics and Pediatric Rheumatology, National Referral Centre of Auto inflammatory Diseases, CEREMAI, CHU Bicetre, Assistance Publique Hopitaux de Paris, University of Paris Sud, Le Kremlin Bicetre, France
    Rheumatology (Oxford) 51:1855-9. 2012
    ..To describe the efficacy and safety of IL-1-targeting drugs, anakinra and canakinumab, in patients with mevalonate kinase deficiency (MKD)...
  14. doi request reprint First clinical description of an infant with interleukin-36-receptor antagonist deficiency successfully treated with anakinra
    Linda Rossi-Semerano
    Department of Pediatrics and Pediatric Rheumatology, National Reference Centre for Auto Inflammatory Diseases, University of Paris Sud, APHP, Hopital de Bicetre, 78, rue du Général Leclerc 94275 Le Kremlin Bicêtre cedex, France
    Pediatrics 132:e1043-7. 2013
    ..We report herein the first exhaustive clinical description of an infant with DITRA who was successfully treated with anakinra. ..
  15. doi request reprint Muckle-Wells syndrome and male hypofertility: a case series
    Tu Anh Tran
    Department of Pediatrics, Pediatric Rheumatology, Reference Center for AutoInflammatory Diseases CEREMAI, Bicetre Hospital, Assistance Publique des Hopitaux de Paris, Universite Paris Sud, Le Kremlin Bicetre, France
    Semin Arthritis Rheum 42:327-31. 2012
    ..Here we investigated whether MWS disease may be associated with impaired fertility in male patients...
  16. doi request reprint Interleukin-1 targeting drugs in familial Mediterranean fever: a case series and a review of the literature
    Ulrich Meinzer
    Division of Paediatric Rheumatology, CEREMAI, Hopital de Bicetre, University of Paris Sud, Le Kremlin Bicetre Cedex, France
    Semin Arthritis Rheum 41:265-71. 2011
    ..The IL-1 receptor antagonist or anti-IL1 monoclonal antibody may therefore represent a new approach to treat FMF. The aim of this report was to evaluate and discuss treatment of FMF with interleukin-1 targeting drugs...
  17. doi request reprint Pediatric Behcet's disease and thromboses
    Brice Krupa
    Service de Pediatrie Generale, Hématologie et Rhumatologie Pédiatrique, Hopital Bicetre, 78 rue Général Leclerc, 94270 Le Kremlin Bicetre, France
    J Rheumatol 38:387-90. 2011
    ..To describe the characteristics of a group of pediatric patients with Behçet's disease (BD) who presented at least 1 episode of thrombosis during their disease course...
  18. doi request reprint Evaluation of chronic recurrent multifocal osteitis in children by whole-body magnetic resonance imaging
    Sophie Guérin-Pfyffer
    Department of Pediatrics and Pediatric Rheumatology, National Reference Center for Auto Inflammatory Disorders, CEREMAI, Bicêtre hôpitaux universitaires Paris Sud, Le Kremlin Bicetre, France
    Joint Bone Spine 79:616-20. 2012
    ..The objectives of our study are to describe the results of the non-invasive whole-body magnetic resonance imaging (WB MRI) procedure in children with CRMO, and to discuss the interest of WB MRI in CRMO's follow-up...
  19. doi request reprint Kawasaki disease: aetiopathogenesis and therapeutic utility of intravenous immunoglobulin
    Caroline Galeotti
    INSERM U 872, Centre de Recherche des Cordeliers, Paris, F 75006, France
    Autoimmun Rev 9:441-8. 2010
    ..They include modification of the cytokine balance, and alteration on both the differentiation and the function of monocytes/macrophages, neutrophils and lymphocytes...
  20. doi request reprint Sustained remission of multicentric Castleman disease in children treated with tocilizumab, an anti-interleukin-6 receptor antibody
    Caroline Galeotti
    Department of Pediatrics, Pediatric Rheumatology, National Referral Centre of Auto inflammatory Diseases, CEREMAI, CHU de Bicetre, Le Kremlin Bicetre, France
    Mol Cancer Ther 11:1623-6. 2012
    ..This patient benefited from sustained remission for a period of 3 years. Tocilizumab was effective and safe in these two children with MCD...
  21. doi request reprint Erdheim-Chester disease in childhood: a challenging diagnosis and treatment
    Tu Anh Tran
    Department of Pediatrics, Pediatric Rheumatology, Bicetre University Hospital, Le Kremlin Bicetre, France
    J Pediatr Hematol Oncol 31:782-6. 2009
    ..It is also the first pediatric case successfully treated with interferon-alpha suggesting that interferon-alpha can be a safe and efficient first-line therapy for this disease in children...
  22. doi request reprint Anakinra for cryopyrin-associated periodic syndrome
    Isabelle Kone-Paut
    Division of Paediatric Rheumatology, Reference Centre for Autoinflammatory Disorders CEREMAI, Bicetre Hospital, University of Paris Sud, Le Kremlin Bicetre Cedex, France
    Expert Rev Clin Immunol 10:7-18. 2014
    ..We describe the history of the 'revival' of CAPS patients through anti-IL-1 treatments with a special focus on anakinra, the first drug used in cohorts with variable disease severity and number of patients. ..
  23. ncbi request reprint Efficacy of etanercept for the treatment of juvenile idiopathic arthritis according to the onset type
    Pierre Quartier
    Hopital Necker Enfants Malades, Paris, France
    Arthritis Rheum 48:1093-101. 2003
    ..To assess the efficacy of etanercept in patients with juvenile idiopathic arthritis (JIA), and to assess the tolerance of these patients to etanercept...
  24. pmc Is Still's Disease an Autoinflammatory Syndrome?
    Linda Rossi-Semerano
    Department of Paediatrics and Paediatric Rheumatology, Bicetre Hospital, National Reference Centre for Autoinflammatory Diseases, 78 rue du General Leclerc, Le Kremlin Bicetre, 94270 Paris, France
    Int J Inflam 2012:480373. 2012
    ..The new insights on the pathogenesis of sJIA have therefore dramatically changed the approach to treatment, with the development of targeted treatments (anti-IL-1 and anti-IL-6 agents) more effective and safer than earlier medications...
  25. doi request reprint Comparative study of complete versus incomplete Kawasaki disease in 59 pediatric patients
    Laurence Perrin
    Service de Pediatrie Generale, Rhumatologie Pédiatrique, Centre de Références des Maladies Auto Inflammatoires, CHU de Bicetre, Assistance Publique Hopitaux de Paris, 94270 Le Kremlin Bicetre, France
    Joint Bone Spine 76:481-5. 2009
    ....
  26. doi request reprint IL-1RA agonist (anakinra) in the treatment of multifocal castleman disease: case report
    Caroline Galeotti
    Department of Pediatrics, Pediatric Rheumatology, National Referral Centre of Auto inflammatory Diseases, CHU de Bicetre, Le Kremlin Bicetre, France
    J Pediatr Hematol Oncol 30:920-4. 2008
    ..This is the first report of anakinra treatment for MCD. We conclude that anti-IL-1 blocking agents could be an interesting treatment alternative for MCD, a chronic debilitating disease, which still carries a poor prognosis...
  27. ncbi request reprint Anakinra is safe and effective in controlling hyperimmunoglobulinaemia D syndrome-associated febrile crisis
    M Cailliez
    AP HM Timone Enfants, F 13385, Marseilles Cedex 05, France
    J Inherit Metab Dis 29:763. 2006
    ..Recently, the IL-1ra analogue anakinra was reported to be successful in aborting the IgD inflammatory attacks in a vaccination model. We report a clinical case of spectacular reduction of febrile attacks in a severe HIDS patient...
  28. ncbi request reprint [Multifocal osteomyelitis as the first manifestation of chronic granulomatous disease]
    F Launay
    Service de Chirurgie Orthopedique, Hôpital Timone Enfants, 264, rue Saint Pierre, 13385 Marseille Cedex 5
    Rev Chir Orthop Reparatrice Appar Mot 89:544-8. 2003
    ..No curative treatment is currently available. Aggressive treatment of each infectious focus with an adapted antibiotic regimen and in certain cases surgical debridement is required in addition to long-term antibiotic prophylaxis...