Srini V Kaveri

Summary

Country: France

Publications

  1. doi request reprint The antiinflammatory IgG
    Srini V Kaveri
    Institut National de la Sante et de la Recherche Medicale, Universite Pierre et Marie Curie, Universite Paris Descartes, Centre de Recherche des Cordeliers, Paris
    N Engl J Med 359:307-9. 2008
  2. ncbi request reprint Intravenous immunoglobulin and dendritic cells
    Namita Misra
    INSERM, U681, Paris, France
    Clin Rev Allergy Immunol 29:201-5. 2005
  3. ncbi request reprint Molecular mechanisms underlying the immunomodulatory effects of mistletoe (Viscum album L.) extracts Iscador
    Sriramulu Elluru
    INSERM U681, Universite Pierre et Marie Curie, Paris 6, France
    Arzneimittelforschung 56:461-6. 2006
  4. ncbi request reprint Intravenous immunoglobulin: an update on the clinical use and mechanisms of action
    Vir Singh Negi
    Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
    J Clin Immunol 27:233-45. 2007
  5. ncbi request reprint Common variable immunodeficiency is associated with defective functions of dendritic cells
    Jagadeesh Bayry
    INSERM U430, Institut des Cordeliers, 15, rue de l Ecole de Medecine, 75006 Paris, France
    Blood 104:2441-3. 2004
  6. pmc Natural antibodies sustain differentiation and maturation of human dendritic cells
    Jagadeesh Bayry
    Institut National de la Santé et de la Recherche Médicale Unité 430 and Université Pierre et Marie Curie, Institut des Cordeliers, 75006 Paris, France
    Proc Natl Acad Sci U S A 101:14210-5. 2004
  7. ncbi request reprint Interleukin-12 is associated with the in vivo anti-tumor effect of mistletoe extracts in B16 mouse melanoma
    Jean Paul Duong Van Huyen
    INSERM U681, Institut des Cordeliers, IFR 58, Paris, France
    Cancer Lett 243:32-7. 2006
  8. ncbi request reprint Catalytic IgG from patients with hemophilia A inactivate therapeutic factor VIII
    Sebastien Lacroix-Desmazes
    Institut National de la Santé et de la Recherche Médicale INSERM Unité 681 and Université Pierre et Marie Curie UPMC Paris 6, Institut des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    J Immunol 177:1355-63. 2006
  9. ncbi request reprint Intravenous immunoglobulin abrogates dendritic cell differentiation induced by interferon-alpha present in serum from patients with systemic lupus erythematosus
    Jagadeesh Bayry
    INSERM Unité 430 and Université Pierre et Marie Curie, Institut des Cordeliers, Paris, France
    Arthritis Rheum 48:3497-502. 2003
  10. ncbi request reprint [Use of intravenous polyclonal immunoglobulins in autoimmune and inflammatory disorders]
    Stéphanie Graff-Dubois
    INSERM U 872, Universite Rene Descartes Paris 5, université Pierre et Marie Curie UPMC Paris 6 et équipe 16 immunopathologie et immunointervention thérapeutique, Centre de Recherche des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Transfus Clin Biol 14:63-8. 2007

Collaborators

Detail Information

Publications64

  1. doi request reprint The antiinflammatory IgG
    Srini V Kaveri
    Institut National de la Sante et de la Recherche Medicale, Universite Pierre et Marie Curie, Universite Paris Descartes, Centre de Recherche des Cordeliers, Paris
    N Engl J Med 359:307-9. 2008
  2. ncbi request reprint Intravenous immunoglobulin and dendritic cells
    Namita Misra
    INSERM, U681, Paris, France
    Clin Rev Allergy Immunol 29:201-5. 2005
    ..Recently, we examined the effects of IVIg on differentiation, maturation, and functions of DCs. We demonstrate that DCs are one of the targets for the immunomodulatory effects of IVIg...
  3. ncbi request reprint Molecular mechanisms underlying the immunomodulatory effects of mistletoe (Viscum album L.) extracts Iscador
    Sriramulu Elluru
    INSERM U681, Universite Pierre et Marie Curie, Paris 6, France
    Arzneimittelforschung 56:461-6. 2006
    ..This review provides an account of the current status of the understanding of the VA-associated immunomodulation in various cell types including lymphoblastoid, monocytic or endothelial cell lines...
  4. ncbi request reprint Intravenous immunoglobulin: an update on the clinical use and mechanisms of action
    Vir Singh Negi
    Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
    J Clin Immunol 27:233-45. 2007
    ....
  5. ncbi request reprint Common variable immunodeficiency is associated with defective functions of dendritic cells
    Jagadeesh Bayry
    INSERM U430, Institut des Cordeliers, 15, rue de l Ecole de Medecine, 75006 Paris, France
    Blood 104:2441-3. 2004
    ....
  6. pmc Natural antibodies sustain differentiation and maturation of human dendritic cells
    Jagadeesh Bayry
    Institut National de la Santé et de la Recherche Médicale Unité 430 and Université Pierre et Marie Curie, Institut des Cordeliers, 75006 Paris, France
    Proc Natl Acad Sci U S A 101:14210-5. 2004
    ..These results suggest that B cells promote bystander DC development through NAbs and the interaction between NAbs and DCs may play a role in steady-state migration of DCs...
  7. ncbi request reprint Interleukin-12 is associated with the in vivo anti-tumor effect of mistletoe extracts in B16 mouse melanoma
    Jean Paul Duong Van Huyen
    INSERM U681, Institut des Cordeliers, IFR 58, Paris, France
    Cancer Lett 243:32-7. 2006
    ..Results from the present study strongly suggest a crucial role of IL-12 in the anti-tumor properties of VA extracts...
  8. ncbi request reprint Catalytic IgG from patients with hemophilia A inactivate therapeutic factor VIII
    Sebastien Lacroix-Desmazes
    Institut National de la Santé et de la Recherche Médicale INSERM Unité 681 and Université Pierre et Marie Curie UPMC Paris 6, Institut des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    J Immunol 177:1355-63. 2006
    ....
  9. ncbi request reprint Intravenous immunoglobulin abrogates dendritic cell differentiation induced by interferon-alpha present in serum from patients with systemic lupus erythematosus
    Jagadeesh Bayry
    INSERM Unité 430 and Université Pierre et Marie Curie, Institut des Cordeliers, Paris, France
    Arthritis Rheum 48:3497-502. 2003
    ..Considering the effect of serum factors, including interferon-alpha (IFNalpha), on the activity of DCs, we investigated the effects of IVIG on the differentiation of DCs mediated by serum from SLE patients...
  10. ncbi request reprint [Use of intravenous polyclonal immunoglobulins in autoimmune and inflammatory disorders]
    Stéphanie Graff-Dubois
    INSERM U 872, Universite Rene Descartes Paris 5, université Pierre et Marie Curie UPMC Paris 6 et équipe 16 immunopathologie et immunointervention thérapeutique, Centre de Recherche des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Transfus Clin Biol 14:63-8. 2007
    ..We discuss here the recent advances in the understanding of immunoregulatory effects of IVIg, and we pointed out the need of new strategies to overcome the predicted increasing worldwide shortage of IVIg...
  11. ncbi request reprint Alterations of self-reactive antibody repertoires in HIV disease: an insight into the role of T cells in the selection of autoreactive B cells
    Dorothea Stahl
    INSERM U430 and Universite Pierre et Marie Curie, Institut des Cordeliers, Paris, France
    Immunol Lett 99:198-208. 2005
    ....
  12. ncbi request reprint Antiangiogenic properties of viscum album extracts are associated with endothelial cytotoxicity
    Sri Ramulu Elluru
    INSERM UMRS 872, Equipe 16 Immunopathology and Therapeutic Intervention, Centre de Recherche des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Anticancer Res 29:2945-50. 2009
    ..Angiogenesis plays an important role in the growth, sustenance and metastasis of tumors. Inhibition of angiogenesis is now being explored as a new therapeutic avenue for cancer...
  13. ncbi request reprint Common variable immunodeficiency: the immune system in chaos
    Jagadeesh Bayry
    INSERM Unité 681 and Université Pierre et Marie Curie, Institut des Cordeliers, 15 rue de l Ecole de Medecine, Paris 75006, France
    Trends Mol Med 11:370-6. 2005
    ..This new information should assist in understanding the pathogenesis of CVID and improving the therapeutic strategies...
  14. ncbi request reprint Comparative study of the anti-inflammatory effect of two intravenous immunoglobulin preparations manufactured by different processes
    Sriramulu Elluru
    INSERM U681, Universite Pierre et Marie Curie, UPMC, Paris 6, Institut des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Immunol Lett 107:58-62. 2006
    ....
  15. ncbi request reprint Comparative study of the sensitivity of lymphoblastoid and transformed monocytic cell lines to the cytotoxic effects of Viscum album extracts of different origin
    Jean Paul Duong Van Huyen
    Unité de Recherche Immunopathologie Humaine, INSERM U430, Hopital Broussais, Paris, France
    Chemotherapy 49:298-302. 2003
    ..While VA Qu FrF, Qu Spez and M Spez were potent inducers of cell death, extracts of VA P, derived from mistletoe plants growing on pine trees, failed to induce any cell death in any of the cell lines examined...
  16. ncbi request reprint Dendritic cells and autoimmunity
    Jagadeesh Bayry
    INSERM U430 and Universite Pierre et Marie Curie, Institut des Cordeliers, 15 rue de l Ecole de Medecine, Paris 75006, France
    Autoimmun Rev 3:183-7. 2004
    ..Direct analysis of DC phenotypes and DC-T-cell interactions in rodent and human autoimmune diseases should shed light on how pathogenesis occurs, and suggest novel avenues of treatment aimed at alleviating deviant DC function...
  17. ncbi request reprint Restricted BV gene usage by factor VIII-reactive CD4+ T cells in inhibitor-positive patients with severe hemophilia A
    Namita Misra
    INSERM U430, Universite Pierre et Marie Curie, Centre de Recherches Biomedicales des Cordeliers, rue de l Ecole de Medecine, 75006 Paris, France
    Thromb Haemost 90:813-22. 2003
    ..perturbations of the CD4+ T cell repertoire that results from oligoclonal expansion of FVIII-specific cells and may be relevant for the design of strategies aimed at modulating the anti-FVIII immune responses by T cell-targeted therapy..
  18. ncbi request reprint Pathophysiology of catalytic antibodies
    Sebastien Lacroix-Desmazes
    INSERM UMRS681, Universite Pierre et Marie Curie, UPMC, Institut des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Immunol Lett 103:3-7. 2006
    ..g. in the context of pregnancy or in the course of autoimmune diseases...
  19. pmc High levels of catalytic antibodies correlate with favorable outcome in sepsis
    Sebastien Lacroix-Desmazes
    Institut National de la Sante et de la Recherche Medicale, Unite 681, Universite Paris VI, Institut des Cordeliers, 15 rue de l Ecole de Medecine, 75006 Paris, France
    Proc Natl Acad Sci U S A 102:4109-13. 2005
    ..Our observations provide the first evidence that hydrolytic antibodies might play a role in recovery from a disease...
  20. ncbi request reprint Catalytic antibodies to factor VIII in haemophilia A
    Sebastien Lacroix-Desmazes
    INSERM U430, Institut des Cordeliers, Paris, France
    Blood Coagul Fibrinolysis 14:S31-4. 2003
    ..Further characterization of these catalytic anti-FVIII antibodies may lead to the identification of novel therapeutic approaches for the future management of FVIII inhibitor patients...
  21. ncbi request reprint Autoantibodies to factor VIII
    Sebastien Lacroix-Desmazes
    INSERM U430, Hôpital Broussais and Universite Pierre et Marie Curie, Paris, France
    Autoimmun Rev 1:105-10. 2002
    ..The implications for the treatment of autoimmune patients with anti-FVIII inhibitors are discussed...
  22. ncbi request reprint Intravenous immunoglobulin for infectious diseases: back to the pre-antibiotic and passive prophylaxis era?
    Jagadeesh Bayry
    INSERM U430 and Universite Pierre et Marie Curie, Institut des Cordeliers, 15 rue de l Ecole de Medecine, 75006, Paris, France
    Trends Pharmacol Sci 25:306-10. 2004
    ....
  23. ncbi request reprint Natural human polyreactive IgM induce apoptosis of lymphoid cell lines and human peripheral blood mononuclear cells
    Sooryanarayana Varambally
    INSERM Unité 430 and Université Pierre et Marie Curie, Institut des Cordeliers, 75006 Paris, France
    Int Immunol 16:517-24. 2004
    ..Our results suggest a role for normal IgM in controlling cell death and proliferation, and imply a possible therapeutic role for IgM in autoimmune and lymphoproliferative disorders...
  24. ncbi request reprint Natural autoantibodies: immune homeostasis and therapeutic intervention
    Jagadeesh Bayry
    Institut des Cordeliers, INSERM U681, , 75006 Paris, France
    Expert Rev Clin Immunol 1:213-22. 2005
    ..This information should lead towards the therapeutic exploitation of natural autoantibodies in the immunotherapy of autoimmune and inflammatory disorders...
  25. ncbi request reprint Inhibition of maturation and function of dendritic cells by intravenous immunoglobulin
    Jagadeesh Bayry
    INSERM U 430 and Université Pierre et Marie Curie, Institut des Cordeliers, Paris, France
    Blood 101:758-65. 2003
    ..Modulation of DC maturation and function by IVIg is of potential relevance to its immunomodulatory effects in controlling specific immune responses in autoimmune diseases, transplantation, and other immune-mediated conditions...
  26. ncbi request reprint Rescuing CD4+CD25+ regulatory T-cell functions in rheumatoid arthritis by cytokine-targeted monoclonal antibody therapy
    Jagadeesh Bayry
    INSERM, UMR S 872, Université Pierre et Marie Curie UPMC Paris 6, Equipe 16 Immunopathology and Therapeutic Immunointervention, Centre de Recherche des Cordeliers, Paris 75006, France
    Drug Discov Today 12:548-52. 2007
    ....
  27. ncbi request reprint Reduced immunoregulatory CD31+ T cells in patients with atherosclerotic abdominal aortic aneurysm
    Giuseppina Caligiuri
    Institut National de la Sante et de la Recherche Medicale INSERM, EMI0016, Paris, France
    Arterioscler Thromb Vasc Biol 26:618-23. 2006
    ..We surmise that these pathological events are controlled by circulating regulatory lymphocytes...
  28. ncbi request reprint Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells
    Jagadeesh Bayry
    The Edward Jenner Institute for Vaccine Research, University of Oxford, Compton, UK
    J Immunol 178:4184-93. 2007
    ..The data show that Tregs induce the generation of semimature DC with the potential to migrate into lymphoid organs, suggesting a possible mechanism by which Tregs down-modulate immune responses...
  29. ncbi request reprint Monoclonal antibody and intravenous immunoglobulin therapy for rheumatic diseases: rationale and mechanisms of action
    Jagadeesh Bayry
    Institut National de la Sante et de la Recherche Medicale INSERM, Universite Rene Descartes, Centre de Recherche des Cordeliers, Paris, France
    Nat Clin Pract Rheumatol 3:262-72. 2007
    ..The success of currently available therapeutic immunoglobulins has led to considerable interest in the identification of novel molecular therapeutic targets in rheumatic diseases...
  30. ncbi request reprint Phosphorylcholine-targeting immunization reduces atherosclerosis
    Giuseppina Caligiuri
    Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie Paris 6, Paris, France
    J Am Coll Cardiol 50:540-6. 2007
    ..The present study evaluated the effect of phosphorylcholine (PC) immunization on the extent of experimental atherosclerosis...
  31. pmc Induction of maturation and activation of human dendritic cells: a mechanism underlying the beneficial effect of Viscum album as complimentary therapy in cancer
    Sri Ramulu Elluru
    Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie PARIS6, UMR S 872, Paris, 75006, France
    BMC Cancer 8:161. 2008
    ..In the present study, we examine the hypothesis that the VA preparations induce activation of human DC that facilitates effective tumor regression...
  32. pmc In silico identified CCR4 antagonists target regulatory T cells and exert adjuvant activity in vaccination
    Jagadeesh Bayry
    The Edward Jenner Institute for Vaccine Research, University of Oxford, Compton, United Kingdom
    Proc Natl Acad Sci U S A 105:10221-6. 2008
    ..The significant adjuvant activity observed provides good evidence supporting our hypothesis that CCR4 is a viable target for rational adjuvant design...
  33. ncbi request reprint Shortage of human intravenous immunoglobulin--reasons and possible solutions
    Jagadeesh Bayry
    INSERM UMRS 872, Universite Rene Descartes, Université Pierre et Marie Curie UPMC Paris 6, Equipe 16 Immunopathology and Therapeutic Intervention, Centre de Recherche des Cordeliers, Paris, France
    Nat Clin Pract Neurol 3:120-1. 2007
  34. ncbi request reprint Sialylated therapeutic IgG: a sweet remedy for inflammatory diseases?
    Jordan D Dimitrov
    INSERM UMRS 872 Equipe 16, Centre de Recherche des Cordeliers, 15, rue de l Ecole de Medecine, Paris 75006, France
    Nephrol Dial Transplant 22:1301-4. 2007
  35. pmc Induction of apoptosis of endothelial cells by Viscum album: a role for anti-tumoral properties of mistletoe lectins
    Jean Paul Duong Van Huyen
    INSERM U430, Hopital Broussais, Paris, France
    Mol Med 8:600-6. 2002
    ..Because endothelial cells (EC) play a pivotal role in tumor angiogenesis, we tested the hypothesis that VA extracts induce endothelial cell death and apoptosis...
  36. ncbi request reprint Autoantibodies to heat shock protein 90 in the human natural antibody repertoire
    Anastas Pashov
    INSERM U430, Hopital Broussais, 96 rue Didot, 75014 Paris, France
    Int Immunol 14:453-61. 2002
    ..The results favor the hypothesis that HSP90 belongs to a subset of highly conserved and immunodominant self antigens that are the primary target for natural autoantibodies in normal human IgG...
  37. ncbi request reprint Molecular characterization of human B domain-specific anti-factor VIII monoclonal antibodies generated in transgenic mice
    Géraldine Lavigne-Lissalde
    CNRS UMR 5160, Faculté de Pharmacie BP 14491, 15 Avenue Charles Flahault, 34093 Montpellier Cedex 5, France
    Thromb Haemost 98:138-47. 2007
    ..Further investigation will allow to better characterize their clinical relevance...
  38. ncbi request reprint [Catalytic antibodies or "abzymes"]
    Sebastien Lacroix-Desmazes
    Med Sci (Paris) 19:519-22. 2003
  39. doi request reprint Modulation of human dendritic cell maturation and function by natural IgG antibodies
    Sri Ramulu Elluru
    Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie Paris 6, UMR S 872, Paris, F 75006, France
    Autoimmun Rev 7:487-90. 2008
    ..Our results suggest that B cells promote bystander DC development through NAbs and the interaction between NAbs and DCs may play a role in steady-state migration of DCs...
  40. doi request reprint Role of natural antibodies in immune homeostasis: IVIg perspective
    Janakiraman Vani
    Centre de Recherche des Cordeliers, Equipe 16 Immunopathology and Therapeutic Immunointervention, Universite Pierre et Marie Curie Paris 6, UMR S 872, Paris, F 75006, France
    Autoimmun Rev 7:440-4. 2008
    ..The therapeutic effects of IVIg most likely reflect the functions of natural antibodies in maintaining immune homeostasis in healthy individuals...
  41. ncbi request reprint Intravenous immunoglobulins in autoimmune and inflammatory diseases: a mechanistic perspective
    Sophie Siberil
    INSERM UMRS 872, Universite Rene Descartes Paris 5, Université Pierre et Marie Curie UPMC Paris 6 75006 Paris, France
    Ann N Y Acad Sci 1110:497-506. 2007
    ..We discuss here the recent advances in the understanding of immunoregulatory effects of IVIg, and we pointed out the need for new strategies to overcome the predicted increasing worldwide shortage of IVIg...
  42. ncbi request reprint Do activated human dendritic cells diminish the suppressive functions of CD4+,CD25+ regulatory T cells? Comment on the article by van Amelsfort et al
    Jagadeesh Bayry
    Arthritis Rheum 56:3874-6. 2007
  43. doi request reprint Factor VIII bypasses CD91/LRP for endocytosis by dendritic cells leading to T-cell activation
    Suryasarathi Dasgupta
    Unite 872, Institut National de la Sante et de la Recherche Medicale, Paris, France
    Haematologica 93:83-9. 2008
    ..We investigated the involvement of CD91 in FVIII endocytosis by human dendritic cells (DC), a model of professional APC...
  44. ncbi request reprint Atheroprotective effect of CD31 receptor globulin through enrichment of circulating regulatory T-cells
    Emilie Groyer
    INSERM UMR S 872, Paris, France
    J Am Coll Cardiol 50:344-50. 2007
    ..This study was designed to evaluate whether replacing CD31 (PECAM-1) signaling can restore the regulation of lymphocyte activation and improve experimental atherosclerosis...
  45. ncbi request reprint Cutting edge: human CD4+CD25+ T cells restrain the maturation and antigen-presenting function of dendritic cells
    Namita Misra
    Institut National de la Sante et de la Recherche Medicale, Unité 430, and Universite Pierre et Marie Curie, Centre de Recherches Biomedicales des Cordeliers, Paris, France
    J Immunol 172:4676-80. 2004
    ..There was an increased IL-10 secretion and reduced expression of costimulatory molecules in DC. Thus, in addition to direct suppressor effect on CD4(+) T cells, regulatory T cells may modulate the immune response through DC...
  46. ncbi request reprint [Immunomodulatory effects of intravenous immunoglobulins]
    Philippe Guilpain
    Service de Medecine Interne, Hopital Cochin, Assistance publique Hôpitaux de Paris et Université Paris V, Paris
    Presse Med 33:1183-94. 2004
    ..These mechanisms of action are multiple and often intricate. However, they are still little known and further investigations are warranted...
  47. ncbi request reprint Peptide decoys selected by phage display block in vitro and in vivo activity of a human anti-FVIII inhibitor
    Sylvie Villard
    Unité Mixte de Recherche 5094 of the Centre National de la Recherche Scientifique Institut National de la Recherche Médicale, Faculte de Pharmacie, Montpellier, France
    Blood 102:949-52. 2003
    ..Peptide 107, in particular, neutralized the activity of Bo2C11 in vitro and restored normal hemostasis in hemophilic mice. Thus, the use of peptide decoys may be a promising new approach for the neutralization of pathologic antibodies...
  48. ncbi request reprint Intravenous immunoglobulin in neurological disorders: a mechanistic perspective
    Namita Misra
    INSERM U681, Université Pierre et Marie Curie Institut des Cordeliers, 15 rue de l Ecole de Medecine, Paris, France
    J Neurol 252:I1-6. 2005
    ....
  49. ncbi request reprint Modulation of dendritic cell maturation and function by B lymphocytes
    Jagadeesh Bayry
    The Edward Jenner Institute for Vaccine Research, Berkshire, United Kingdom
    J Immunol 175:15-20. 2005
    ..Conversely, efficient cross-presentation of Ags by DC pulsed with immune complexes provides an alternative approach in the immunotherapy of cancer and infectious diseases...
  50. ncbi request reprint The prevalence of proteolytic antibodies against factor VIII in hemophilia A
    Sebastien Lacroix-Desmazes
    INSERM Unité 430 and Université Pierre et Marie Curie, Hopital Broussais, Paris, France
    N Engl J Med 346:662-7. 2002
    ..The hydrolysis of factor VIII by anti--factor VIII antibodies has been proposed as a mechanism of inactivation of factor VIII...
  51. ncbi request reprint Amelioration of differentiation of dendritic cells from CVID patients by intravenous immunoglobulin
    Jagadeesh Bayry
    Am J Med 118:1439-40. 2005
  52. ncbi request reprint Antigenic properties of peptide mimotopes of HIV-1-associated carbohydrate antigens
    Anastas Pashov
    Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA
    J Biol Chem 280:28959-65. 2005
    ..These results suggested the potential to fine-tune the antibody response to carbohydrate antigens by modifying structural features of peptide mimotope-based immunogens...
  53. ncbi request reprint Human antibodies accelerate the rate of remyelination following lysolecithin-induced demyelination in mice
    Allan J Bieber
    Department of Neurology, Mayo Medical and Graduate Schools, Rochester, Minnesota 55905, USA
    Glia 37:241-9. 2002
    ..We propose the use of human polyclonal IgM or specific human monoclonal IgM antibodies as potential therapies to enhance myelin repair following CNS injury and disease...
  54. ncbi request reprint Autoantibodies to factor VIII with catalytic activity
    Jagadeesh Bayry
    INSERM, U430, Hopital Broussais, 96, rue Didot, 75014 Paris, France
    Autoimmun Rev 2:30-5. 2003
    ..The characterization of FVIII inhibitors as site-specific proteases may provide new approaches to the treatment of inhibitors...
  55. ncbi request reprint Red blood cell transfusions are associated with alterations in self-reactive antibody repertoires of plasma IgM and IgG, independent of the presence of a specific immune response toward RBC antigens
    Dorothea Stahl
    INSERM U430 and Universite Pierre et Marie Curie, Hopital Broussais, 75014 Paris, France
    Clin Immunol 105:25-35. 2002
    ..05). We conclude that the challenge of the immune system with allogeneic RBC antigens influences self-reactive antibody repertoires of plasma IgM and IgG, independent of the presence of a specific immune response toward RBC antigens...
  56. ncbi request reprint Immunomodulation of autoimmunity by intravenous immunoglobulin through interaction with immune networks
    Jagadeesh Bayry
    INSERM U430 and Universite Pierre et Marie Curie, Hopital Broussais, Paris, France
    Vox Sang 83:49-52. 2002
  57. doi request reprint Natural anti-endothelial cell antibodies
    Amélie Servettaz
    Universite Paris Descartes, Faculte de Medecine, UPRES EA 4058, Paris, France
    Autoimmun Rev 7:426-30. 2008
    ..As reported for other types of natural autoantibodies, natural AECA could exert anti-inflammatory and anti-thrombotic functions. In addition, they could play a role in the control of EC activation...
  58. ncbi request reprint From 'perfect mix' to 'potion magique'-- regulatory T cells and anti-inflammatory cytokines as adjuvant targets
    Jagadeesh Bayry
    Nat Rev Microbiol 6:C1; author reply C2. 2008
  59. ncbi request reprint Efficacy of regulatory T-cell immunotherapy: are inflammatory cytokines key determinants?
    Jagadeesh Bayry
    Nat Rev Immunol 8:1p following 86; author reply 1p following 86. 2008
  60. ncbi request reprint Expansion of CD4+CD25+ regulatory T cells by intravenous immunoglobulin: a critical factor in controlling experimental autoimmune encephalomyelitis
    Amal Ephrem
    Centre de Recherche des Cordeliers, Universite Pierre et Marie Curie Paris 6, UMR S 872, Inserm U872, France
    Blood 111:715-22. 2008
    ..In conclusion, our results highlight a novel mechanism of action of IVIg and provide a rationale to test the use of IVIg as an immunomodulatory tool to enhance Treg in early onset MS and other autoimmune and inflammatory conditions...
  61. ncbi request reprint Intravenous immunoglobulin in autoimmune and inflammatory diseases: more than mere transfer of antibodies
    Sophie Siberil
    Centre de Recherche des Cordeliers, Equipe 16 Immunopathology and Therapeutic Immunointervention, Universite Pierre et Marie Curie Paris 6, UMR S 872, 15 Rue de l Ecole de Medicine, Paris, France
    Transfus Apher Sci 37:103-7. 2007
    ..These mechanisms of action of IVIg reflect the importance of natural antibodies in the maintenance of immune homeostasis. We discuss here the recent advances in the understanding of immunoregulatory effects of IVIg...
  62. ncbi request reprint The proatherogenic role of T cells requires cell division and is dependent on the stage of the disease
    Jamila Khallou-Laschet
    INSERM U681, Institut des Cordeliers Université Paris 6 UPMC, Paris, France
    Arterioscler Thromb Vasc Biol 26:353-8. 2006
    ....
  63. ncbi request reprint Comment on: Human intravenous immunoglobulin for experimental streptococcal toxic shock: bacterial clearance and modulation of inflammation
    Govindarajan Rajagopalan
    J Antimicrob Chemother 59:157-9; author reply 159-60. 2007
  64. doi request reprint Identification of target antigens of antiendothelial cell antibodies in healthy individuals: A proteomic approach
    Amélie Servettaz
    Faculte de Medecine, UPRES EA 4058, Universite Paris Descartes, Paris, France
    Proteomics 8:1000-8. 2008
    ..IgG from all of the healthy individuals tested recognized a restricted set of highly conserved ubiquitous proteins playing key roles in cell biology and maintenance of homeostasis...