L Karila

Summary

Country: France

Publications

  1. ncbi request reprint Sexual addiction or hypersexual disorder: different terms for the same problem? A review of the literature
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, 12 avenue Paul Vaillant Couturier, Villejuif 94800, France
    Curr Pharm Des 20:4012-20. 2014
  2. ncbi request reprint Acute and long-term effects of cannabis use: a review
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, 12 avenue Paul Vaillant Couturier, Villejuif 94800, France
    Curr Pharm Des 20:4112-8. 2014
  3. doi request reprint [Cocaine addiction: current data for the clinician]
    Laurent Karila
    Universite Paris Sud 11, AP HP, Hôpital Universitaire Paul Brousse, Centre d enseignement, de Recherche et de Traitement des Addictions, CEA INSERM U1000, Villejuif, France Electronic address
    Presse Med 43:9-17. 2014
  4. doi request reprint [Tobacco use and illicit substance use disorders: what should we have to do?]
    Laurent Karila
    AP HP, Universite Paris Sud 11, Hôpital Universitaire Paul Brousse, Centre d enseignement, de Recherche et de Traitement des Addictions, CEA INSERM U1000, 94800 Villejuif, France
    Presse Med 42:795-805. 2013
  5. ncbi request reprint Diagnosis and consequences of cocaine addiction
    L Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, Paris Sud 11 University, AP HP, INSERM CEA U1000, Villejuif, France
    Curr Med Chem 19:5612-8. 2012
  6. ncbi request reprint [Drug addiction and addictive behavior. Part 2 - alcohol, psychoactive and illicit substances]
    Laurent Karila
    Universite Paris Sud, Le Kremlin Bicetre, F 94276, France
    Rev Prat 58:1131-40; quiz 1149. 2008
  7. ncbi request reprint [Cocaine: from recreational use to dependence]
    Laurent Karila
    Centre d enseignement, de Recherche et de Traitement des Addictions, Hôpital Universitaire Paul Brousse, AP HP, CEA Inserm U797, Universite Paris XI, 94804 Villejuif Cedex
    Rev Prat 59:821-5. 2009
  8. ncbi request reprint [Complications of cocaine addiction]
    Laurent Karila
    Clinique Montevideo, 92100 Boulogne Billancourt
    Rev Prat 59:825-9. 2009
  9. ncbi request reprint [Therapeutic approaches to cocaine addiction]
    Laurent Karila
    Centre d enseignement, de Recherche et de Traitement des Addictions, Hôpital Universitaire Paul Brousse, AP HP, INSERM U669, Universite Paris XI, 94804 Villejuif Cedex
    Rev Prat 59:830-4. 2009
  10. pmc Pharmacological approaches to methamphetamine dependence: a focused review
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, Paris XI University, AP HP, CEA INSERM U1000, Villejuif, France
    Br J Clin Pharmacol 69:578-92. 2010

Detail Information

Publications36

  1. ncbi request reprint Sexual addiction or hypersexual disorder: different terms for the same problem? A review of the literature
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, 12 avenue Paul Vaillant Couturier, Villejuif 94800, France
    Curr Pharm Des 20:4012-20. 2014
    ..Psychiatric and somatic comorbidities that frequently occur with sexual addiction should be integrated into the therapeutic process. Group-based treatments should also be attempted. ..
  2. ncbi request reprint Acute and long-term effects of cannabis use: a review
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, 12 avenue Paul Vaillant Couturier, Villejuif 94800, France
    Curr Pharm Des 20:4112-8. 2014
    ....
  3. doi request reprint [Cocaine addiction: current data for the clinician]
    Laurent Karila
    Universite Paris Sud 11, AP HP, Hôpital Universitaire Paul Brousse, Centre d enseignement, de Recherche et de Traitement des Addictions, CEA INSERM U1000, Villejuif, France Electronic address
    Presse Med 43:9-17. 2014
    ..Targeting somatic and psychiatric comorbidity is another way to use pharmacological treatments in addictions. ..
  4. doi request reprint [Tobacco use and illicit substance use disorders: what should we have to do?]
    Laurent Karila
    AP HP, Universite Paris Sud 11, Hôpital Universitaire Paul Brousse, Centre d enseignement, de Recherche et de Traitement des Addictions, CEA INSERM U1000, 94800 Villejuif, France
    Presse Med 42:795-805. 2013
    ..Currently, there are no official medical recommendations for the treatment of tobacco addiction in illicit polysubstance users...
  5. ncbi request reprint Diagnosis and consequences of cocaine addiction
    L Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, Paris Sud 11 University, AP HP, INSERM CEA U1000, Villejuif, France
    Curr Med Chem 19:5612-8. 2012
    ..Literature searches were conducted for the period from January 1985 to February 2012 using PubMed, EMBASE, PsycInfo, and Google Scholar...
  6. ncbi request reprint [Drug addiction and addictive behavior. Part 2 - alcohol, psychoactive and illicit substances]
    Laurent Karila
    Universite Paris Sud, Le Kremlin Bicetre, F 94276, France
    Rev Prat 58:1131-40; quiz 1149. 2008
  7. ncbi request reprint [Cocaine: from recreational use to dependence]
    Laurent Karila
    Centre d enseignement, de Recherche et de Traitement des Addictions, Hôpital Universitaire Paul Brousse, AP HP, CEA Inserm U797, Universite Paris XI, 94804 Villejuif Cedex
    Rev Prat 59:821-5. 2009
    ....
  8. ncbi request reprint [Complications of cocaine addiction]
    Laurent Karila
    Clinique Montevideo, 92100 Boulogne Billancourt
    Rev Prat 59:825-9. 2009
    ..Psychiatric complications found in clinical practice are major depressive disorders, cocaine-induced paranoia, cocaine-induced compulsive foraging and panic attacks...
  9. ncbi request reprint [Therapeutic approaches to cocaine addiction]
    Laurent Karila
    Centre d enseignement, de Recherche et de Traitement des Addictions, Hôpital Universitaire Paul Brousse, AP HP, INSERM U669, Universite Paris XI, 94804 Villejuif Cedex
    Rev Prat 59:830-4. 2009
    ..Partial agonists at the dopamine D2 receptor and anticocaine vaccines are other promising treatment approaches. It is important to clearly differentiate the detoxification treatment and the relapse prevention treatment phases...
  10. pmc Pharmacological approaches to methamphetamine dependence: a focused review
    Laurent Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital, Paris XI University, AP HP, CEA INSERM U1000, Villejuif, France
    Br J Clin Pharmacol 69:578-92. 2010
    ..Despite the lack of success in most studies to date, increasing efforts are being made to develop medications for the treatment of methamphetamine dependence and several promising agents are targets of further research...
  11. ncbi request reprint [Current pharmacotherapies and immunotherapy in cocaine addiction]
    Laurent Karila
    Universite Paris Sud, F 94276 Le Kremlin Bicetre, France
    Presse Med 37:689-98. 2008
    ..However, this must be confirmed in larger patient populations...
  12. ncbi request reprint New treatments for cocaine dependence: a focused review
    Laurent Karila
    INSERM, U797, Hospital Department Frederic Joliot, 12BM, Orsay, France
    Int J Neuropsychopharmacol 11:425-38. 2008
    ..An anti-cocaine vaccine and several compounds in preclinical development have also shown promise. Findings from early clinical trials must be confirmed in larger, less selective patient populations...
  13. doi request reprint [Which are the predictive factors to be ranked within the 500 first medical students at the national ranking exam? A cross-sectional study of the 2009 class]
    L Karila
    CEA INSERM U1000, Département d Addictologie, Centre d enseignement, de recherche et de traitements des addictions, Hopital Paul Brousse, Assistance Publique Hopitaux de Paris, Faculte de Medecine Paris Sud, Universite Paris XI, 12, avenue Paul Vaillant Couturier, 94804 Villejuif Cedex, France
    Rev Med Interne 32:400-5. 2011
    ..The objective of this study was to analyze, during a transversal study, the predictive sociodemographic and individual factors to be ranked within the first 500 medical students in the 2009 French national ranking exam (NRE)...
  14. ncbi request reprint [Short- and long-term consequences of prenatal exposure to cannabis]
    L Karila
    Département d Addictologie et de Psychiatrie, Hopital Paul Brousse, Villejuif
    J Gynecol Obstet Biol Reprod (Paris) 35:62-70. 2006
    ..and behavior of newborns, children and teenagers...
  15. doi request reprint Protective effect against alcohol dependence of the thermolabile variant of MTHFR
    Raphael Saffroy
    Service de Biochimie et Biologie Moléculaire, INSERM 602, Universite Paris XI, Hopital Paul Brousse, Assistance Publique Hopitaux de Paris, 94800 Villejuif, France
    Drug Alcohol Depend 96:30-6. 2008
    ..Our objective was to study the prevalence of the MTHFR C677T polymorphism in alcohol-dependent subjects and the influence of this polymorphism on symptoms associated with alcoholism...
  16. doi request reprint Career choices of medical students: a national survey of 1780 students
    Jeremie H Lefevre
    Department of Digestive Surgery, Saint Antoine Hospital Assistance Publique Hôpitaux de Paris AP HP, Pierre et Marie Curie Faculty of Medicine, University of Paris VI, Paris, France
    Med Educ 44:603-12. 2010
    ....
  17. ncbi request reprint Is love passion an addictive disorder?
    Michel Reynaud
    INSERM, U, Paris, France
    Am J Drug Alcohol Abuse 36:261-7. 2010
    ..Inquiry regarding the relationship between passionate love and addiction has long been a topic of intense debate. Recent advances in neurobiology now allow for an examination between these two states...
  18. doi request reprint Motivation of French medical students to pursue surgical careers: results of national survey of 1742 students
    Jeremie H Lefevre
    Service de Chirurgie Digestive, Hopital Saint Antoine, Assistance Publique Hopitaux de Paris, Groupe Hospitalo Universitaire EST, Faculte de Medecine Pierre et Marie Curie, Universite Paris VI, 184, rue du Faubourg Saint Antoine, 75012 Paris, France
    J Visc Surg 147:e181-6. 2010
    ..Analyze the aspirations and personal motivations behind the choice of surgical specialties in a large sample of students in their 6th year of medical school...
  19. ncbi request reprint [Is the learning process of "evidence-based medicine" influenced by determined factors? Results from a national survey of 1870 French students in their sixth year]
    Morgan Roupret
    Universite Paris VI, Faculte de Medecine Pierre et Marie Curie, Assistance Publique Hopitaux de Paris AP HP, Hopital Pitie Salpetriere, Service d Urologie, 75013 Paris, France
    Presse Med 39:e126-33. 2010
    ..To investigate the baseline level of knowledge of evidence based medicine (EBM) concepts in a sample of French medical students in their sixth year of training...
  20. doi request reprint [Doctors to be have a lack of interest for general practice. Results from a national Poll in a population of 1 870 undergraduate french medical students concerning speciality choice]
    Jeremie H Lefevre
    Service de Chirurgie digestive de l hôpital Saint Antoine, Assistance Publique Hopitaux de Paris, Groupe Hospitalo Universitaire EST, Faculte de Medecine Pierre et Marie Curie, Universite Paris VI, Paris, France
    Presse Med 39:e58-65. 2010
    ..Analyze the professional wishes of a large sample of medical students in their 6(th) year before the National Ranking Exam...
  21. doi request reprint Association between MTHFR 677C-T polymorphism and alcohol dependence according to Lesch and Babor typology
    Amine Benyamina
    Service d Addictologie, Hopital Paul Brousse, Paul Vaillant Couturier, Villejuif Cedex, Assistance Publique Hopitaux de Paris, France
    Addict Biol 14:503-5. 2009
    ..MTHFR TT was also associated with hyperhomocysteinemia. Determining MTHFR 677C-T genotype, folate and vitamin B12 levels could assist physicians in identifying type 3 patients and improve addictions management...
  22. doi request reprint Association between ABCB1 C3435T polymorphism and increased risk of cannabis dependence
    Amine Benyamina
    INSERM, U669, Paris, France
    Prog Neuropsychopharmacol Biol Psychiatry 33:1270-4. 2009
    ..ABCB1 polymorphisms may alter Delta9THC distribution, its psychoactive effects and individual vulnerability to dependence. These results pave the way to a new pharmacogenetic hypothesis in cannabis dependence...
  23. ncbi request reprint [Cocaine induced psychotic disorders: a review]
    L Karila
    Centre d enseignement, de Recherche et de Traitement des Addictions, Hôpital Universitaire Paul Brousse, Assistance Publique des Hopitaux de Paris, France
    Rev Med Liege 65:623-7. 2010
    ..This review is based on Medline, EMBASE, PsycINFO and Google Scholar searches of English and French-language articles published between 1969 and February, 2010...
  24. ncbi request reprint The reliability and validity of the French version of the Cocaine Craving Questionnaire-Brief
    L Karila
    Addiction Research and Treatment Center, Paul Brousse Hospital Assistance Publique Hôpitaux de Paris AP HP, Villejuif, France
    Curr Pharm Des 17:1369-75. 2011
    ..However, no craving scale exists in French. The objective of our study was to assess the reliability and validity of a French language version of the 10-item Cocaine Craving Questionnaire-Brief (CCQ-Brief)...
  25. ncbi request reprint [Validation of a questionnaire to screen for harmful use of alcohol and cannabis in the general population: CRAFFT-ADOSPA]
    Laurent Karila
    Département d Addictologie et de Psychiatrie, Hôpital Universitaire Paul Brousse, APHP INSERM U669, Villejuif
    Presse Med 36:582-90. 2007
    ..The aim of the ADOTECNO study was therefore to develop simple and efficient tools for this purpose...
  26. ncbi request reprint [What nosographic framework for excessive tanning?]
    A Petit
    Service de Psychiatrie, addictologie et tabacologie, Faculte de Medecine, Universite Paris VII, Hopital Bichat, AP HP, 75018 Paris, France Electronic address
    Encephale 40:174-9. 2014
    ..This finding is based on the observations of many dermatologists who report an addictive relationship in their patients with tanning cabins despite announcement of the diagnosis of malignant melanoma...
  27. ncbi request reprint [Acute and chronic cognitive disorders caused by cannabis use]
    Laurent Karila
    Département de psychiatrie et d addictologie, Hôpital Universitaire Paul Brousse, 94804 Villejuif Cedex
    Rev Prat 55:23-6; discussion 27-9. 2005
    ..Methodological differences could partly affect these observations. Therefore it seems necessary to develop studies with larger samples...
  28. doi request reprint [Gamma-hydroxybutyric acid (GHB): more than a date rape drug, a potentially addictive drug]
    Laurent Karila
    Universite Paris Sud, F 94276 Le Kremlin Bicetre, France
    Presse Med 38:1526-38. 2009
    ..These undesirable effects and especially the deaths appear to have prompted campaigns to limit the use of GHB. Clinicians must also be aware of GBL, which is being sold and used as a substitute for GHB...
  29. doi request reprint [Neuroimaging and cocaine: mapping dependence?]
    Gérard Lambert
    Clinique Montevideo, F 92100 Boulogne Billancourt, France
    Presse Med 37:679-88. 2008
    ..Neuroimaging has no recognized clinical indications in the field of dependence or more generally in psychiatry, but it is an essential research tool...
  30. doi request reprint [Cognitive modifications associated with tobacco smoking]
    Marie Lecacheux
    Universite Paris Sud, Le Kremlin Bicetre, INSERM U669, Paris, Hopital Paul Brousse, Villejuif, France
    Presse Med 38:1241-52. 2009
    ..It is associated with cognitive disorders which tend to maintain addictive mechanisms. In the short term, the nicotine contained in tobacco enhances attention and memory...
  31. ncbi request reprint [Progressive cannabis-induced arteritis: a clinical thromboangiitis obliterans sub-group?]
    Laurent Karila
    Département de psychiatrie et d addictologie, Hôpital Universitaire Paul Brousse, Universite Paris XI, Villejuif 94
    Presse Med 33:21-3. 2004
    ..Since the end of the nineteen-nineties, cannabis is not only incriminated in the onset of thromboangiitis obliterans but also in inducing artheromatous lesions in young subjects...
  32. ncbi request reprint [Cognitive disorders and chronic use of cannabis]
    Laurent Karila
    Département de Psychiatrie et d Addictologie Pr M Reynaud, Hôpital Universitaire Paul Brousse, Paris XI, 12 14, avenue Paul Vaillant Couturier, 94808 Villejuif Cedex
    Ann Med Interne (Paris) 154:S58-64. 2003
    ..Based on data reported in the literature, we report the cognitive effects associated with chronic use of cannabis as well as its social and educational consequences...
  33. ncbi request reprint [Substance abuse in adolescents]
    Jean Vignau
    Service d addictologie CHRU clinique de la Charité 59037 Lille
    Rev Prat 53:1315-9. 2003
    ..Treatment of problematic drug abuse in adolescents is based on both contextual interventions including systematic support of the families and a multidisciplinary approach...
  34. ncbi request reprint Self-mutilation induced by cocaine abuse: the pleasure of bleeding
    Laurent Karila
    Universite Paris Sud, U669, Le Kremlin Bicêtre 94
    Presse Med 36:235-7. 2007
    ..Amphetamine use, but not cocaine use, has previously been associated with severe self-injurious behavior...
  35. ncbi request reprint Intravenous zolpidem abuse: a case for serotonin depletion
    Amine Benyamina
    Am J Addict 16:534. 2007
  36. ncbi request reprint [Role of psychostimulants in hyperactive children]
    Frédéric Kochman
    Unité de pédopsychiatrie D Daniel Bayart EPSM Agglomération lilloise 59871 Saint André
    Rev Prat 52:2017-22. 2002
    ..e. social and/or educative problems). As a differential diagnosis, the hypothesis of an early-onset bipolar disorder should be systematically assessed because of the huge symptomatic overlaps between the two illnesses...