Carine Karachi

Summary

Country: France

Publications

  1. ncbi Three-dimensional cartography of functional territories in the human striatopallidal complex by using calbindin immunoreactivity
    Carine Karachi
    INSERM U289, Neurologie et Thérapeutique Expérimentale, Hopital de la Salpetriere, 75013 Paris, France
    J Comp Neurol 450:122-34. 2002
  2. ncbi The pallidosubthalamic projection: an anatomical substrate for nonmotor functions of the subthalamic nucleus in primates
    Carine Karachi
    INSERM U289, Neurologie et Thérapeutique Expérimentale, Hopital de la Salpetriere, Paris, France
    Mov Disord 20:172-80. 2005
  3. ncbi Dysfunction of the subthalamic nucleus induces behavioral and movement disorders in monkeys
    Carine Karachi
    INSERM, UMR_S679, Neurology and Experimental Therapeutics, Paris, France
    Mov Disord 24:1183-92. 2009
  4. pmc Normal and pathological gait: what we learn from Parkinson's disease
    David Grabli
    Universite Pierre et Marie Curie Paris 6, CR Icm, UMR S975, Paris, France
    J Neurol Neurosurg Psychiatry 83:979-85. 2012
  5. doi Thalamic stimulation for tremor: can target determination be improved?
    Eric Bardinet
    Universite Pierre et Marie Curie PARIS6, Centre de Recherche de l Institut du Cerveau et de la Moelle Epiniere, Paris, France
    Mov Disord 26:307-12. 2011
  6. doi Does unilateral basal ganglia activity functionally influence the contralateral side? What we can learn from STN stimulation in patients with Parkinson's disease
    Yohann Brun
    1Centre de Recherche de l Institut du Cerveau et de la Moelle Épiniere, UMR S975, Paris, France
    J Neurophysiol 108:1575-83. 2012
  7. ncbi Internal pallidum and substantia nigra control different parts of the mesopontine reticular formation in primate
    Anne Sophie Rolland
    Universite Pierre et Marie Curie Paris 6, CR Icm, UMR S975, INSERM, U975, CNRS, UMR 7225, Assistance Publique Hopitaux de Paris, Groupe Pitié Salpêtrière, Paris, France
    Mov Disord 26:1648-56. 2011
  8. doi Processing of emotional information in the human subthalamic nucleus
    Anne Buot
    Centre de Recherche de l Institut du Cerveau et de la Moelle épinière CRICM, Universite Pierre et Marie Curie Paris 6, Paris, France
    J Neurol Neurosurg Psychiatry 84:1331-8. 2013
  9. doi Gait disorders in parkinsonian monkeys with pedunculopontine nucleus lesions: a tale of two systems
    David Grabli
    CR Icm, UMR S975, Universite Pierre et Marie Curie Paris 6, Paris, France, INSERM, U975, Paris, France
    J Neurosci 33:11986-93. 2013
  10. doi Evidence for a dopaminergic innervation of the pedunculopontine nucleus in monkeys, and its drastic reduction after MPTP intoxication
    Anne Sophie Rolland
    INSERM, UMR_S975, Experimental Therapeutics of Neurodegeneration, Paris, France
    J Neurochem 110:1321-9. 2009

Collaborators

Detail Information

Publications21

  1. ncbi Three-dimensional cartography of functional territories in the human striatopallidal complex by using calbindin immunoreactivity
    Carine Karachi
    INSERM U289, Neurologie et Thérapeutique Expérimentale, Hopital de la Salpetriere, 75013 Paris, France
    J Comp Neurol 450:122-34. 2002
    ..This three-dimensional partitioning of the human striatopallidal complex could help to define functional targets for high-frequency stimulation with greater accuracy and help to identify new stimulation sites...
  2. ncbi The pallidosubthalamic projection: an anatomical substrate for nonmotor functions of the subthalamic nucleus in primates
    Carine Karachi
    INSERM U289, Neurologie et Thérapeutique Expérimentale, Hopital de la Salpetriere, Paris, France
    Mov Disord 20:172-80. 2005
    ..These data provide a functional cartography of this structure in primates and suggest that behavioral disorders observed in stimulated parkinsonian patients could result from a dysfunction of the limbic part of the STN...
  3. ncbi Dysfunction of the subthalamic nucleus induces behavioral and movement disorders in monkeys
    Carine Karachi
    INSERM, UMR_S679, Neurology and Experimental Therapeutics, Paris, France
    Mov Disord 24:1183-92. 2009
    ..Our study supports the hypothesis that the anteromedial part of the STN is involved in behavioral control...
  4. pmc Normal and pathological gait: what we learn from Parkinson's disease
    David Grabli
    Universite Pierre et Marie Curie Paris 6, CR Icm, UMR S975, Paris, France
    J Neurol Neurosurg Psychiatry 83:979-85. 2012
    ..In addition, we review recent evidence regarding functional neurosurgery for gait disorders in PD and propose new directions for future therapeutic research...
  5. doi Thalamic stimulation for tremor: can target determination be improved?
    Eric Bardinet
    Universite Pierre et Marie Curie PARIS6, Centre de Recherche de l Institut du Cerveau et de la Moelle Epiniere, Paris, France
    Mov Disord 26:307-12. 2011
    ..In clinical practice, this means that microelectrode exploration during Vim surgery should include at least one trajectory more medial than the statistical target...
  6. doi Does unilateral basal ganglia activity functionally influence the contralateral side? What we can learn from STN stimulation in patients with Parkinson's disease
    Yohann Brun
    1Centre de Recherche de l Institut du Cerveau et de la Moelle Épiniere, UMR S975, Paris, France
    J Neurophysiol 108:1575-83. 2012
    ....
  7. ncbi Internal pallidum and substantia nigra control different parts of the mesopontine reticular formation in primate
    Anne Sophie Rolland
    Universite Pierre et Marie Curie Paris 6, CR Icm, UMR S975, INSERM, U975, CNRS, UMR 7225, Assistance Publique Hopitaux de Paris, Groupe Pitié Salpêtrière, Paris, France
    Mov Disord 26:1648-56. 2011
    ..These findings support the functional hypothesis that the nigro-cuneiform nucleus pathway could control axial posture whereas the pallido-pedunculopontine nucleus pathway could modulate locomotion...
  8. doi Processing of emotional information in the human subthalamic nucleus
    Anne Buot
    Centre de Recherche de l Institut du Cerveau et de la Moelle épinière CRICM, Universite Pierre et Marie Curie Paris 6, Paris, France
    J Neurol Neurosurg Psychiatry 84:1331-8. 2013
    ..In both Parkinson's disease and OCD patients, STN-HFS can trigger abnormal behaviours, such as hypomania and impulsivity...
  9. doi Gait disorders in parkinsonian monkeys with pedunculopontine nucleus lesions: a tale of two systems
    David Grabli
    CR Icm, UMR S975, Universite Pierre et Marie Curie Paris 6, Paris, France, INSERM, U975, Paris, France
    J Neurosci 33:11986-93. 2013
    ..Thus, we obtained a primate model of PD that could be useful to test symptomatic treatments for these heavily disabling symptoms. ..
  10. doi Evidence for a dopaminergic innervation of the pedunculopontine nucleus in monkeys, and its drastic reduction after MPTP intoxication
    Anne Sophie Rolland
    INSERM, UMR_S975, Experimental Therapeutics of Neurodegeneration, Paris, France
    J Neurochem 110:1321-9. 2009
    ....
  11. pmc High-level gait and balance disorders in the elderly: a midbrain disease?
    Adèle Demain
    Centre de Recherche de l Institut du Cerveau et de la Moelle épinière CRICM, Universite Pierre et Marie Curie Paris 6, UMR S975, Paris, France
    J Neurol 261:196-206. 2014
    ....
  12. doi Functional parcellation of the lateral mesencephalus
    Carine Karachi
    Assistance Publique Hopitaux de Paris, Groupe Hospitalier Pitie Salpetriere, 75013 Paris, France
    J Neurosci 32:9396-401. 2012
    ....
  13. ncbi A three-dimensional, histological and deformable atlas of the human basal ganglia. I. Atlas construction based on immunohistochemical and MRI data
    Jerome Yelnik
    INSERM U679, Neurologie et Thérapeutique Expérimentale, Hopital de la Salpetriere, Universite Pierre et Marie Curie, Faculte de Medecine, Paris, France
    Neuroimage 34:618-38. 2007
    ..This latter aspect will be presented in a forthcoming paper...
  14. pmc Cholinergic mesencephalic neurons are involved in gait and postural disorders in Parkinson disease
    Carine Karachi
    Universite Pierre et Marie Curie Paris 6, CR Icm, UMR S975, Paris, France
    J Clin Invest 120:2745-54. 2010
    ..Our data therefore reveal that the cholinergic neurons of the PPN play a central role in controlling gait and posture and represent a possible target for pharmacological treatment of gait disorders in PD...
  15. ncbi Functional magnetic resonance imaging suggests automatization of the cortical response to inspiratory threshold loading in humans
    Mathieu Raux
    Department of Experimental Medicine, Transcranial Magnetic Stimulation Laboratory McGill University Health Centre, Montreal, QC, Canada Université Paris 6, ER10UPMC Neurophysiologie Respiratoire Expérimentale et Clinique, Paris, France Assistance Publique Hôpitaux de Paris, Departement d Anesthesie Reanimation, Groupe Hospitalier Pitie Salpetriere, Paris, France
    Respir Physiol Neurobiol 189:571-80. 2013
    ..We conclude that the respiratory-related cortical activation observed in response to ITL is likely due to automated, attention-independent mechanisms. Also, ITL activates cortical circuits right from the first breath...
  16. pmc Sleep Disorders in Parkinsonian Macaques: Effects of l-Dopa Treatment and Pedunculopontine Nucleus Lesion
    Hayat Belaid
    Institut National de la Santé et de la Recherche Médicale Unité Mixte de Recherche S975, Universite Pierre et Marie Curie Paris 06, Unité Mixte de Recherche S975, CNRS Unité Mixte de Recherche 7225, and Centre de Recherche Institut du Cerveau et de la Moelle, Groupe Hospitalier Pitie Salpetriere, 75013 Paris, France
    J Neurosci 34:9124-33. 2014
    ..Our data demonstrate the efficacy of l-dopa treatment in improving sleep disorders in parkinsonian monkeys, and that adding a cholinergic PPN lesion improves sleep quality after transient sleep impairment. ..
  17. doi Bilateral deep brain stimulation of the pallidum for myoclonus-dystonia due to ε-sarcoglycan mutations: a pilot study
    Julie Azoulay-Zyss
    Service de Neurologie, Groupe Hospitalier Paris Saint Joseph, Universite Paris 5, Paris, France
    Arch Neurol 68:94-8. 2011
    ..To assess the efficacy of bilateral deep brain stimulation of the internal pallidum in patients with myoclonus-dystonia due to genetically proved ε-sarcoglycan (SGCE-M-D) deficiency...
  18. doi Critical roles for anterior insula and dorsal striatum in punishment-based avoidance learning
    Stefano Palminteri
    Motivation, Brain and Behavior MBB Team, Institut du Cerveau et de la Moëlle épinière ICM, Hopital de la Pitie Salpetriere, 75013 Paris, France
    Neuron 76:998-1009. 2012
    ....
  19. ncbi Behavioural disorders induced by external globus pallidus dysfunction in primates II. Anatomical study
    Chantal Francois
    Neurologie et Thérapeutique Expérimentale, INSERM U289, Hopital de la Salpetriere, Paris, France
    Brain 127:2055-70. 2004
    ..This study provides the basis for further researches with a therapeutical viewpoint...
  20. doi High-frequency stimulation of the anterior subthalamic nucleus reduces stereotyped behaviors in primates
    Nicolas Baup
    Departement de Psychiatrie, Centre Hospitalier Saint Anne, Paris F 75014, France
    J Neurosci 28:8785-8. 2008
    ..Electrode trajectories, reconstructed postmortem, confirmed that the effective contacts were in the anterior STN. DBS in the limbic STN might therefore provide relief from the severe stereotyped behaviors observed in OCD and TS...
  21. doi Internal pallidal and thalamic stimulation in patients with Tourette syndrome
    Marie Laure Welter
    National Institute of Health and Medical Research INSERM, Unit 679, Pierre et Marie Curie University Paris 6, France
    Arch Neurol 65:952-7. 2008
    ....