N Kamar

Summary

Country: France

Publications

  1. ncbi request reprint Diabetes mellitus after kidney transplantation: a French multicentre observational study
    Nassim Kamar
    Service de Nephrologie, Dialyse et Transplantation, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Nephrol Dial Transplant 22:1986-93. 2007
  2. pmc OSAKA trial: a randomized, controlled trial comparing tacrolimus QD and BD in kidney transplantation
    Laetitia Albano
    1 Department of Nephrology, Centre Hospitalier Universitaire de Nice, Nice, France 2 Internal Medicine II Nephrology, University Medical Center, Regensburg, Germany 3 General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany 4 Department of Transplantology and Surgery, District Public Hospital, Poznan, Poland 5 Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic 6 Department of Nephrology, Dialysis and Organ Transplantation, Toulouse University Hospital, Toulouse, France 7 Address correspondence to Nassim Kamar, M D, Department of Nephrology, Dialysis and Organ Transplantation, Toulouse University Hospital, CHU Rangueil TSA 50032, 31059 Toulouse Cedex 9, France
    Transplantation 96:897-903. 2013
  3. doi request reprint Hepatitis C virus and kidney disease
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Clin Res Hepatol Gastroenterol 37:328-33. 2013
  4. doi request reprint Incidence of donor-specific antibodies in kidney transplant patients following conversion to an everolimus-based calcineurin inhibitor-free regimen
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Clin Transplant 27:455-62. 2013
  5. doi request reprint Hepatitis E virus infection
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Curr Opin Gastroenterol 29:271-8. 2013
  6. doi request reprint Hepatitis E virus infection in immunosuppressed patients: natural history and therapy
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Semin Liver Dis 33:62-70. 2013
  7. doi request reprint Do kidney histology lesions predict long-term kidney function after liver transplantation?
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Universite Paul Sabatier, Toulouse, France
    Clin Transplant 26:927-34. 2012
  8. doi request reprint Hepatitis E virus: what transplant physicians should know
    N Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Am J Transplant 12:2281-7. 2012
  9. doi request reprint Impact of post-transplant anemia on patient and graft survival rates after kidney transplantation: a meta-analysis
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Clin Transplant 26:461-9. 2012
  10. doi request reprint Hepatitis E virus and the kidney in solid-organ transplant patients
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Transplantation 93:617-23. 2012

Detail Information

Publications157 found, 100 shown here

  1. ncbi request reprint Diabetes mellitus after kidney transplantation: a French multicentre observational study
    Nassim Kamar
    Service de Nephrologie, Dialyse et Transplantation, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Nephrol Dial Transplant 22:1986-93. 2007
    ..New-onset diabetes mellitus (NODM)-a common complication of kidney transplantation-is associated with increases in graft loss, morbidity and mortality...
  2. pmc OSAKA trial: a randomized, controlled trial comparing tacrolimus QD and BD in kidney transplantation
    Laetitia Albano
    1 Department of Nephrology, Centre Hospitalier Universitaire de Nice, Nice, France 2 Internal Medicine II Nephrology, University Medical Center, Regensburg, Germany 3 General, Visceral and Transplantation Surgery, Hannover Medical School, Hannover, Germany 4 Department of Transplantology and Surgery, District Public Hospital, Poznan, Poland 5 Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic 6 Department of Nephrology, Dialysis and Organ Transplantation, Toulouse University Hospital, Toulouse, France 7 Address correspondence to Nassim Kamar, M D, Department of Nephrology, Dialysis and Organ Transplantation, Toulouse University Hospital, CHU Rangueil TSA 50032, 31059 Toulouse Cedex 9, France
    Transplantation 96:897-903. 2013
    ..The once-daily (QD), prolonged-release formulation of tacrolimus has been shown to improve adherence versus twice-daily (BD) tacrolimus. Treatment nonadherence in transplant recipients has been associated with poor graft outcomes...
  3. doi request reprint Hepatitis C virus and kidney disease
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Clin Res Hepatol Gastroenterol 37:328-33. 2013
    ..The available data also suggest that occult HCV infection does not exist in dialysis and kidney transplant patients. ..
  4. doi request reprint Incidence of donor-specific antibodies in kidney transplant patients following conversion to an everolimus-based calcineurin inhibitor-free regimen
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Clin Transplant 27:455-62. 2013
    ..A study including a larger number of patients is required to determine whether a CNI-free everolimus-based immunosuppression significantly increases DSAs formation...
  5. doi request reprint Hepatitis E virus infection
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Curr Opin Gastroenterol 29:271-8. 2013
    ..Herein, we review the progress made in studying the epidemiology, hepatic, and extrahepatic manifestations, and the treatment of HEV infection, over the past 2 years...
  6. doi request reprint Hepatitis E virus infection in immunosuppressed patients: natural history and therapy
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Semin Liver Dis 33:62-70. 2013
    ..The aim of this review is to summarize the incidence, natural history, risk factors, and treatment of HEV infections in immunosuppressed patients. HEV-induced extrahepatic manifestations are described...
  7. doi request reprint Do kidney histology lesions predict long-term kidney function after liver transplantation?
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Universite Paul Sabatier, Toulouse, France
    Clin Transplant 26:927-34. 2012
    ..Long-term kidney function seems to be predicted by the kidney vascular lesions...
  8. doi request reprint Hepatitis E virus: what transplant physicians should know
    N Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Am J Transplant 12:2281-7. 2012
    ..In this comprehensive minireview, we summarize the current knowledge on HEV infection in transplant patients, that is, its prevalence, incidence, natural history and therapy...
  9. doi request reprint Impact of post-transplant anemia on patient and graft survival rates after kidney transplantation: a meta-analysis
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Clin Transplant 26:461-9. 2012
    ..14 [1.11-1.16]). This meta-analysis reveals that the association between PTA and DPWFG varies with PTA definition and adjustment for confounders. In all sub-meta-analyses, PTA was significantly associated with DCGL...
  10. doi request reprint Hepatitis E virus and the kidney in solid-organ transplant patients
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Transplantation 93:617-23. 2012
    ..Hepatitis E virus (HEV) infection is an emerging disease in industrialized countries. Few data regarding genotype 3 HEV extrahepatic manifestations exist...
  11. doi request reprint A multicenter, randomized trial of increased mycophenolic acid dose using enteric-coated mycophenolate sodium with reduced tacrolimus exposure in maintenance kidney transplant recipients
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, Hopital Rangueil, Toulouse, France
    Clin Nephrol 77:126-36. 2012
    ..Adverse events overall, but not those with a suspected relation to EC-MPS, were higher with ECMPS 1,440 mg/d...
  12. pmc Kinetics of plasmatic cytokines and cystatin C during and after hemodialysis in septic shock-related acute renal failure
    Nicolas Mayeur
    Anesthesia and Intensive Care Unit Department, GRCB 48, Purpan University Hospital, Place du Dr Baylac, TSA 40031, 31059 Toulouse Cedex 9, France
    Crit Care 14:R115. 2010
    ..In this study, we described p cytokines and cystatin C variations during and after hemodialysis in septic-shock patients with acute kidney injury (AKI)...
  13. ncbi request reprint Effect of mycophenolate mofetil monotherapy on T-cell functions and inosine monophosphate dehydrogenase activity in patients undergoing a kidney transplantation
    N Kamar
    Department of Nephrology, Charite Hospital, Berlin, Germany
    Transplant Proc 38:2292-4. 2006
    ..In conclusion, administration of 1 g of MMF was associated with a transient decrease in CD25 expression in addition to a temporary dramatic decrease in both T-cell proliferation and IMPDH activity...
  14. ncbi request reprint New onset diabetes mellitus incidence and risk factors in kidney transplantation: results of the observational cross-sectional study diapason
    N Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Transplant Proc 38:2295-7. 2006
    ..A study was implemented in a French population of kidney transplants. The incidence and risk factors of NODM were analysed. Diabetes was defined according to American Diabetes/World Health Organization guidelines...
  15. ncbi request reprint [The evolution of the hypervariable region-1 of hepatitis C virus may predict liver fibrosis outcome after renal transplantation]
    Nassim Kamar
    Service de Nephrologie, Dialyse et Transplantation, CHU de Toulouse Rangueil, 1, TSA 50032, Toulouse, France
    Nephrol Ther 1:345-54. 2005
    ..The diversification of the HVR-1 of the HCV genome might be used to predict liver fibrosis outcome...
  16. ncbi request reprint Impact of mycophenolic acid dose modifications on renal function after kidney transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Exp Clin Transplant 4:510-7. 2006
    ....
  17. ncbi request reprint Renal function and histology in kidney transplant patients receiving tacrolimus and sirolimus or mycophenolate mofetil
    Nassim Kamar
    Nephrology, Dialysis, and Transplantation, CHU Rangueil, Toulouse, France
    Exp Clin Transplant 4:532-6. 2006
    ..The aim of this study was to assess the effects of tacrolimus in combination with either sirolimus (n = 10) or mycophenolate mofetil (n = 7) on renal function and renal histopathologic factors 6 and 12 months after kidney transplantation...
  18. doi request reprint Predictive factors for cytomegalovirus reactivation in cytomegalovirus-seropositive kidney-transplant patients
    Nassim Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    J Med Virol 80:1012-7. 2008
    ..Hence, CMV reactivation is frequent after kidney transplantation. CMV prophylaxis in CMV seropositive kidney-transplant patients should be offered to avoid CMV-related side-effects...
  19. ncbi request reprint Effects of intraoperative versus postoperative administration of rabbit antithymocyte antibodies on 1-year renal function in renal transplant patients
    Nassim Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Exp Clin Transplant 4:429-38. 2006
    ..The aim of our study was to prospectively assess 1-year allograft outcomes and the evolution of lymphocyte subsets in a group of renal transplant patients who had received intraoperative rabbit antithymocyte antibodies (RATG)...
  20. doi request reprint [Hepatitis E infection in dialysis and after transplantation]
    Nassim Kamar
    Service de Nephrologie, dialyse et transplantation multi organes, CHU Rangueil, TSA 50032, 31059 Toulouse Cedex 9, France
    Nephrol Ther 6:83-7. 2010
    ..The reduction of immunosuppressive drugs could be considered as a first-line therapeutic option...
  21. doi request reprint Pegylated interferon-alpha for treating chronic hepatitis E virus infection after liver transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, Centre Hospitalier Universitaire, Toulouse, France
    Clin Infect Dis 50:e30-3. 2010
    ..A virological response was sustained for 6 and 5 months in 2 patients after Peg-IFN-alpha-2a therapy was completed. A relapse was observed in the third patient...
  22. doi request reprint Influence of immunosuppressive therapy on the natural history of genotype 3 hepatitis-E virus infection after organ transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, CHU Rangueil, Toulouse, France
    Transplantation 89:353-60. 2010
    ..Hepatitis-E virus (HEV) infection can be responsible for chronic hepatitis in solid-organ transplant patients...
  23. doi request reprint Impact of very early high doses of recombinant erythropoietin on anemia and allograft function in de novo kidney-transplant patients
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Transpl Int 23:277-84. 2010
    ..High doses of ESA within the first month of kidney transplantation have no impact on anemia or renal function by 1 month post-transplant...
  24. doi request reprint Incidence and predictive factors for infectious disease after rituximab therapy in kidney-transplant patients
    N Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, INSERM U858, CHU Rangueil, Toulouse, France
    Am J Transplant 10:89-98. 2010
    ..After kidney transplantation, the use of rituximab is associated with a high risk of infectious disease and death related to infectious disease...
  25. pmc Early plasmapheresis and rituximab for acute humoral rejection after ABO-compatible liver transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, CHU Rangueil, TSA 50032, 31059 Toulouse Cedex 9, France
    World J Gastroenterol 15:3426-30. 2009
    ..We conclude that plasmapheresis should be started as soon as AHR is diagnosed, and be associated with a B-cell depleting agent. Rituximab may be considered as a first-line therapy...
  26. doi request reprint Hepatitis E virus and chronic hepatitis in organ-transplant recipients
    Nassim Kamar
    Department of Nephrology, Dialysis, and Multiorgan Transplantation, Centre Hospitalier Universitaire, Rangueil, France
    N Engl J Med 358:811-7. 2008
    ..The time from transplantation to diagnosis was significantly shorter and the total counts of lymphocytes and of CD2, CD3, and CD4 T cells were significantly lower in patients in whom chronic disease developed...
  27. doi request reprint Successful retransplantation of a kidney allograft affected by thrombotic microangiopathy into a second transplant recipient
    Nassim Kamar
    Department of Nephrology, Dialysis, and Multiorgan Transplantation, University Hospital, CHU Rangueil, Toulouse Cedex, France
    Am J Kidney Dis 52:591-4. 2008
    ..This might increase the number of kidney allografts from extended criteria donors...
  28. doi request reprint Hepatitis E virus-related cirrhosis in kidney- and kidney-pancreas-transplant recipients
    N Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, and INSERM U858, IFR 31, CHU Rangueil, Toulouse, France
    Am J Transplant 8:1744-8. 2008
    ..In both cases, a liver biopsy showed cirrhosis. We conclude that HEV infection cannot only evolve to chronic hepatitis, but can also be responsible for rapidly progressing cirrhosis in organ-transplant patients...
  29. doi request reprint Pharmacodynamic effects of cinacalcet after kidney transplantation: once- versus twice-daily dose
    Nassim Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, Toulouse University Hospital, Toulouse, France
    Nephrol Dial Transplant 23:3720-6. 2008
    ..i.d...
  30. ncbi request reprint Hepatitis C virus-related kidney disease: an overview
    N Kamar
    Department of Nephrology, CHU Rangueil, Toulouse University Hospital, Toulouse, France
    Clin Nephrol 69:149-60. 2008
    ..In liver-transplant patients, in addition to anti-HCV therapy, rituximab might be also used...
  31. doi request reprint [Monitoring of calcineurin inhibitors induced-nephrotoxicity]
    N Kamar
    Service de Nephrologie, Dialyse et Transplantation d organes, CHU de Toulouse Rangueil, 1, avenue Jean Poulhes, TSA 50032, 31059 Toulouse cedex 09, France
    Nephrol Ther 4:S13-S17. 2008
    ..CNIs dose reduction or conversion to proliferating signal inhibitors may be a therapeutic alternative...
  32. ncbi request reprint Conversion from sirolimus to everolimus in maintenance renal transplant recipients within a calcineurin inhibitor-free regimen: results of a 6-month pilot study
    N Kamar
    Nephrology, Dialysis and Multi Organ Transplantation, CHU Rangueil, Toulouse Cedex 4, France
    Clin Nephrol 70:118-25. 2008
    ..To provide data on conversion of kidney transplant patients from sirolimus to everolimus...
  33. ncbi request reprint Treatment of focal segmental glomerular sclerosis with rituximab: 2 case reports
    N Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, Toulouse University Hospital, Toulouse, France
    Clin Nephrol 67:250-4. 2007
    ..Primary focal segmental glomerular sclerosis (FSGS) recurs in 20 - 40% of patients after kidney transplantation. Rituximab has been used to treat several glomerular diseases...
  34. pmc Pharmacodynamic evaluation of the first dose of mycophenolate mofetil before kidney transplantation
    Nassim Kamar
    Department of Nephrology, Charite Universitaetsmedizin Berlin, Berlin, Germany
    Clin J Am Soc Nephrol 4:936-42. 2009
    ....
  35. doi request reprint Mycophenolic acid 12-hour area under the curve in de novo liver transplant patients given mycophenolate mofetil at fixed versus concentration-controlled doses
    Nassim Kamar
    Department of Nephrology, Dialysis and Multi Organ Transplantation, CHU Rangueil, Toulouse, France
    Ther Drug Monit 31:451-6. 2009
    ..There was a trend toward a lower proportion of patients with MPA AUC0-12h below 30 mg x h/L in the concentration-controlled group. No difference in outcome was found between both groups...
  36. doi request reprint Hepatitis E virus-induced neurological symptoms in a kidney-transplant patient with chronic hepatitis
    N Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Am J Transplant 10:1321-4. 2010
    ..The discovery of quasispecies compartmentalization and its temporal association suggests that neurological symptoms could be linked to the emergence of neurotropic variants...
  37. ncbi request reprint Impact of early or delayed cyclosporine on delayed graft function in renal transplant recipients: a randomized, multicenter study
    N Kamar
    Department of Nephrology Transplantation, Hopital Rangueil, Toulouse, France
    Am J Transplant 6:1042-8. 2006
    ..5% of delayed CsA-ME patients (n.s.). Both regimens were well tolerated. These data suggest that early or delayed introduction of CsA-ME results in similar renal function in renal transplant patients regardless of DGF risk level...
  38. ncbi request reprint Intrahepatic cytokine profile in renal-transplant patients infected by hepatitis C virus
    Nassim Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    J Med Virol 76:482-8. 2005
    ..17, P=0.045). Intrahepatic Th1 cytokine profile seems to be predominant in patients with extensive fibrosis and activity scores, suggesting that it might be responsible for liver injury in renal transplant patients...
  39. doi request reprint Kidney histology and function in liver transplant patients
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Nephrol Dial Transplant 26:2355-61. 2011
    ..Chronic kidney disease is a common complication after liver transplantation. However, few reports regarding kidney histology exist for this setting...
  40. pmc Hepatitis E virus and neurologic disorders
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, Centre Hospitalier Universitaire Rangueil, Toulouse, France
    Emerg Infect Dis 17:173-9. 2011
    ..Neurologic outcomes were complete resolution (n = 3), improvement with residual neurologic deficit (n = 3), and no improvement (n = 1). Neurologic disorders are an emerging extrahepatic manifestation of HEV infection...
  41. doi request reprint Ribavirin therapy inhibits viral replication on patients with chronic hepatitis e virus infection
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Gastroenterology 139:1612-8. 2010
    ..We assessed the antiviral effect of ribavirin monotherapy in patients with chronic HEV infection following kidney transplantation...
  42. doi request reprint Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Gastroenterology 140:1481-9. 2011
    ....
  43. doi request reprint Three-month pegylated interferon-alpha-2a therapy for chronic hepatitis E virus infection in a haemodialysis patient
    Nassim Kamar
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, Toulouse Cedex 9, France
    Nephrol Dial Transplant 25:2792-5. 2010
    ....
  44. ncbi request reprint Acute hepatitis and renal function impairment related to infection by hepatitis E virus in a renal allograft recipient
    Nassim Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse, France
    Am J Kidney Dis 45:193-6. 2005
    ....
  45. ncbi request reprint Amantadine therapy in renal transplant patients with hepatitis C virus infection
    Nassim Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Toulouse Rangueil, TSA 50032, 31059 Toulouse Cedex 9, France
    J Clin Virol 30:110-4. 2004
    ..To date, there is no safe and efficient treatment of hepatitis C virus (HCV) infection after renal transplantation. Recently, there were encouraging reports after using amantadine in HCV-positive immunocompetent patients...
  46. ncbi request reprint Assessment of glomerular and tubular functions in renal transplant patients receiving cyclosporine A in combination with either sirolimus or everolimus
    N Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse Cedex, France
    Clin Nephrol 63:80-6. 2005
    ....
  47. ncbi request reprint Predictive factors for anemia within the first year after orthotopic liver transplantation
    J Guitard
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Transplant Proc 38:2342-5. 2006
    ..We concluded that anemia was highly prevalent within the first year of post-OLT. This observation deserves further investigation and appropriate treatment...
  48. ncbi request reprint Hepatitis C virus viral load after conversion from tacrolimus to cyclosporine in liver transplant patients: a pilot study
    J Guitard
    Department of Nephrology, Dialysis, and Multiorgan Transplant Unit, CHU Rangueil, 1 avenue Jean Poulhes, 31059 Toulouse, France
    Transplant Proc 39:2603-5. 2007
    ..We assessed whether conversion from tacrolimus (TAC) to cyclosporine (CsA) was associated with a reduction in hepatitis C virus (HCV) viral load among HCV-positive liver transplant (OLT) patients...
  49. ncbi request reprint Monitoring HCMV infection with quantitative real-time PCR in HCMV-positive orthotopic liver transplant recipients, and predictive factors for treatment of the first episode of HCMV viremia
    A Pillet
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Transplant Proc 38:2335-8. 2006
    ..0443). The only factor that predicted treatment for the first episode of HCMV DNAemia was an alkaline phosphatase level >150 UI/mL at the time of the first HCMV reactivation [odds ratio 20 (1.96 to 203.3); P = .01]...
  50. ncbi request reprint Predictive factors for cytomegalovirus infection after orthotopic liver transplantation using an ultrasensitive polymerase chain reaction assay
    G Basse
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, Toulouse, France
    Transplant Proc 38:2339-41. 2006
    ..2), donor age >45 years (odds ratio = 11.4) and lymphocyte count at M2 <1300/mm(3) (odds ratio = 7.33). This study showed that the major factors associated with CMV infection were recipient CMV status, donor age, and lymphocyte count...
  51. ncbi request reprint Efficacy and safety of induction therapy with rabbit antithymocyte globulins in liver transplantation for hepatitis C
    N Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Toulouse Rangueil, 31059 Toulouse Cedex 9, France
    Transplant Proc 36:2757-61. 2004
    ..The aim of our study was to assess the safety and efficacy of induction therapy using rabbit antithymocyte globulin antibodies (RATG)...
  52. doi request reprint T-cell function in maintenance renal transplant patients receiving mycophenolate mofetil and steroids with or without tacrolimus
    C Canivet
    Department of Nephrology, Toulouse, France
    Transplant Proc 40:3422-3. 2008
    ..As expected, intralymphocytic interleukin-2 (IL-2) and tumor necrosis factor-alpha (TNF-alpha) expressions were higher in patients not receiving CNIs...
  53. ncbi request reprint Tolerability of enteric-coated mycophenolate sodium to 1 year in combination with cyclosporine and corticosteroids in renal transplant recipients
    L Rostaing
    Department of Nephrology Transplantation, Hopital Rangueil, Toulouse, France
    Transplant Proc 38:2860-3. 2006
    ..Gastrointestinal adverse events were responsible for dose reduction or interruption in only 5% of patients...
  54. doi request reprint JC virus DNA in the peripheral blood of renal transplant patients: a 1-year prospective follow-up in France
    C Mengelle
    Department of Virology, University Hospital, CH Toulouse, Cedex, France
    J Med Virol 83:132-6. 2011
    ..JCV replication must still be diagnosed and differentiated from BK virus infection because of its non-aggressive course...
  55. doi request reprint [Domino transplantation of a living-donor kidney graft affected by thrombotic microangiopathy: surgical aspects]
    F Sallusto
    Service d Urologie, Transplantation Renale, Andrologie, CHU de Rangueil, 1, avenue Jean Poulhes, 31059 Toulouse, France
    Prog Urol 19:513-6. 2009
    ....
  56. ncbi request reprint Acute renal failure following liver transplantation with induction therapy
    J Guitard
    Multiorgan Transplant Unit, University Hospital, Toulouse, France
    Clin Nephrol 65:103-12. 2006
    ..To identify the predictive factors for acute renal failure (ARF) in a retrospective study of 100 orthotopic liver transplantations (OLT) performed in 94 patients between 2000 and 2003...
  57. ncbi request reprint Predictive factors of postrenal transplant anemia
    A Turkowski-Duhem
    Department of Nephrology and Transplantation, Hopital, Rangueil, Toulouse, France
    Transplant Proc 37:1009-11. 2005
    ..We included 99 renal transplants performed in our department in 2001, for whom the graft was still functioning at 1 year...
  58. ncbi request reprint [Hepatitis C virus infection in renal-transplant patients]
    N Kamar
    Service de Nephrologie, Dialyse et Transplantation, CHU Toulouse Rangueil
    Nephrologie 25:9-15. 2004
    ..To date, there is no efficient treatment of HCV infection after renal transplantation. Consequently, it is mandatory to treat by alpha-interferon all HCV-positive/RNA-positive dialysis patients waiting for renal transplantation...
  59. ncbi request reprint [Is there a place for ribavirin in the treatment for renal transplant patients infected by hepatitis C virus?]
    N Kamar
    Service de Nephrologie, Dialyse et Transplantation, CHU Toulouse Rangueil, Toulouse
    Nephrologie 24:89-94. 2003
    ..It impact upon renal function remains unknown. Nevertheless when proteinuria is present it disappears...
  60. ncbi request reprint A third renal transplantation: is it relevant and is it worth it?
    A H Reboux
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Transplant Proc 37:4199-202. 2005
    ..Most patients were highly sensitized with 1 (0-4) HLA (classes I + II) incompatibility between donor and recipient...
  61. ncbi request reprint A monocentric observational study of darbepoetin alfa in anemic hepatitis-C-virus transplant patients treated with ribavirin
    Nassim Kamar
    Department of Nephrology, Toulouse University Hospital, France
    Exp Clin Transplant 6:271-5. 2008
    ..Darbepoetin alfa is used to treat renal anemia; however, little information is available concerning its use during the posttransplant period, especially in HCV-positive patients treated with ribavirin for active hepatitis C...
  62. doi request reprint FTY720 Inhibits Tumor Necrosis Factor-alpha-Induced Proliferation and Extracellular Signal-Regulated Kinase Phosphorylation of Human Smooth Muscle Cells
    T Bohler
    INSERM U858 I2MR EQ 10 Artériosclérose et Artériosclérose de Greffe, CHU Rangueil, Toulouse, France
    Transplant Proc 41:705-6. 2009
    ..We concluded that FTY720 may be a useful drug to inhibit chronic vascular rejection...
  63. ncbi request reprint Relapse of membranous glomerulopathy after kidney transplantation: sustained remittance induced by rituximab
    H Weclawiak
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Clin Nephrol 69:373-6. 2008
    ..Remission was observed before the third rituximab injection. After a follow-up of 42 months, the patient was still in remission, i.e., microalbuminuria of 107 mg/day...
  64. ncbi request reprint Long-term ribavirin therapy in hepatitis C virus-positive renal transplant patients: effects on renal function and liver histology
    Nassim Kamar
    Department of Nephrology, Dialysis, and Transplantation, CHU Rangueil, Toulouse, France
    Am J Kidney Dis 42:184-92. 2003
    ..The aims of this study were the evaluation of the efficacy and the safety of ribavirin monotherapy in 16 HCV-(+) RT patients (group A) matched to 32 HCV-(+) RT patients (group B) who did not receive ribavirin...
  65. ncbi request reprint Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus
    Viorica Bumbea
    Multiorgan Transplant Unit, University Hospital, Toulouse, France
    Nephrol Dial Transplant 20:2517-23. 2005
    ..Switching from calcineurin inhibitors (CNIs) to sirolimus might improve renal function in chronic renal transplant patients...
  66. doi request reprint Disseminated Ochroconis gallopava infection in a heart transplant patient
    I Cardeau-Desangles
    Department of Nephrology, Dialysis and Organ Transplantation, Rangueil University Hospital, Toulouse, France
    Transpl Infect Dis 15:E115-8. 2013
    ..Herein, we report a rare case of disseminated O. gallopava infection that involved lung, subcutaneous area, brain and peritoneum in a heart transplant recipient. Despite voriconazole therapy, the patient died 2 months after diagnosis...
  67. ncbi request reprint Does cyclosporine have a beneficial effect on the course of chronic hepatitis C infection after renal transplantation?
    N Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Transplant Proc 38:1329-32. 2006
    ..Cyclosporine might have beneficial effects on the natural course of HCV infection after renal transplantation...
  68. ncbi request reprint Prospective evaluation of BK virus DNAemia in renal transplant patients and their transplant outcome
    G Basse
    Department of Nephrology, Dialysis and Multiorgan Transplantation, Toulouse, France
    Transplant Proc 39:84-7. 2007
    ..After renal transplantation, the prevalence of BK virus (BKV) viruria, viremia, and nephritis (BKVAN) has been estimated at 30%, 13%, and 8%, respectively...
  69. ncbi request reprint Rituximab therapy for acute humoral rejection after kidney transplantation
    Stanislas Faguer
    Department of Nephrology, Dialysis and Multiorgan Transplantation, University Hospital, CHU Rangueil, Toulouse, France
    Transplantation 83:1277-80. 2007
    ..At last follow-up, DSA had disappeared or decreased in four cases. Rituximab therapy, in addition to PE, might be of benefit for RT patients presenting with AHR...
  70. ncbi request reprint Rituximab therapy for mixed cryoglobulinemia in seven renal transplant patients
    G Basse
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, 1 avenue Jean Poulhes, TSA 50032, 31059 Toulouse Cedex 9, France
    Transplant Proc 38:2308-10. 2006
    ..We concluded that rituximab therapy is effective in cryoglobulin-related renal dysfunction in renal transplant patients but, due to chronic immunosuppression, this may be achieved at the expense of infectious complications...
  71. ncbi request reprint Treatment of hepatitis C-virus-related glomerulonephritis
    N Kamar
    Department of Nephrology, Dialysis, and Multiorgan Transplantation, CHU Rangueil, Toulouse University Hospital, Toulouse, France
    Kidney Int 69:436-9. 2006
    ..During the acute phase, plasmapheresis and steroid pulses can be used. However, future prospective, controlled, and randomized studies are still required to establish evidence-based guidelines to treat HCV-related glomerulopathies...
  72. doi request reprint Disseminated herpes simplex type-2 (HSV-2) infection after solid-organ transplantation
    G Basse
    Department of Nephrology, Dialysis, and Multi Organ Transplantation, CHU, Rangueil, University Hospital, 1 av Jean Poulhes, TSA 50032, 31059, Toulouse Cedex 9, France
    Infection 36:62-4. 2008
    ..Although rare, HSV-2-disseminated infection, in the context of organ transplantation may be life-threatening, but can be cured if ACV therapy is initiated early in the course of this disease...
  73. ncbi request reprint Darbepoetin-alfa in renal-transplant patients: an observational monocentric study
    D Ribes
    Nephrology and Kidney Transplantation Department, CHU Rangueil, Toulouse University Hospital, France
    Clin Nephrol 69:102-6. 2008
    ..Although recombinant human erythropoietin (rHuEPO) is used in post-transplant anemic patients, little information is available concerning the use of darbepoetin-alfa (DA) in this population...
  74. ncbi request reprint Comparison of induction based on continuous vs discontinuous administration of antithymocyte globulins in renal transplant patients: efficacy and long-term safety
    L Esposito
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil Toulouse, France
    Transplant Proc 37:892-4. 2005
    ..This retrospective study sought to compare two modes of administration of antithymocyte globulin (RATG) after renal transplantation...
  75. ncbi request reprint Linezolid-induced interstitial nephritis in a kidney-transplant patient
    L Esposito
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Clin Nephrol 68:327-9. 2007
    ..Because of the potential side effects of linezolid, i.e. myelosuppression and possibly nephrotoxicity, we recommend close monitoring of these parameters when linezolid therapy is attempted in kidney transplant patients...
  76. doi request reprint Influenza A (H1N1) virus-induced hepatocellular injury in a kidney transplant patient
    M Daude
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Transpl Infect Dis 13:70-2. 2011
    ..The hepatocellular injury episode resolved after the patient had been placed on oseltamivir therapy. This observation suggests that acute hepatocellular injury could be linked to the influenza H1N1 virus...
  77. doi request reprint Duodenal villous atrophy: a cause of chronic diarrhea after solid-organ transplantation
    H Weclawiak
    Department of Nephrology, Dialysis and Organ Transplantation, CHU Rangueil, Toulouse, France
    Am J Transplant 11:575-82. 2011
    ..In conclusion, DVA is a frequent cause of chronic diarrhea in SOT recipients. MPA therapy is the most frequent cause of DVA. An OGD should be proposed to all transplant recipients who present with persistent diarrhea...
  78. doi request reprint HLA class I antibodies provoke graft arteriosclerosis in human arteries transplanted into SCID/beige mice
    S Galvani
    INSERM U858 I2MR Team 10, IFR 31, CHU Rangueil, Toulouse, France
    Am J Transplant 9:2607-14. 2009
    ..Humoral alloreactivity toward HLA may thus play a causal role for the development of CVR and this opens new possibilities for the treatment of CVR...
  79. ncbi request reprint Viral infections after kidney transplantation
    L Rostaing
    Unit of Nephrology, Dialysis and Organ Translplantation, CHU Rangueil, Toulouse, France
    Minerva Urol Nefrol 63:59-71. 2011
    ..Thanks to modern laboratory technique, and a formidable antiviral armamentarium, viral infections in organ transplant patients i) can be easily detected at early stages, and ii) can be efficiently treated...
  80. ncbi request reprint An unusual cause of acute renal failure in a kidney transplant recipient: salmonella enteritidis post-infectious glomerulonephritis
    A Pillet
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Clin Nephrol 67:321-4. 2007
    ..A few cases of acute renal failure with glomerular syndrome, caused by S. enteritidis infection, have been reported in the literature, but none have been proven by histological findings...
  81. ncbi request reprint Predictive factors for anemia six and twelve months after orthotopic liver transplantation
    Joelle Guitard
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, France
    Transplantation 81:1525-31. 2006
    ..The aim of our study was to determine the prevalence and predictive factors for post-transplant anemia (PTA) at 6 (M6) and 12 (M12) months after orthotopic liver-transplant (OLT) in a cohort of 97 consecutive patients...
  82. ncbi request reprint Prevalence of cryoglobulinemia and autoimmunity markers in renal-transplant patients
    S Faguer
    Nephrology, Dialysis, and Multiorgan Transplant Unit, University Hospital, CHU Rangueil, Toulouse, France
    Clin Nephrol 69:239-43. 2008
    ..To examine the prevalence of cryoglobulinemia (Cryo) and autoimmune markers in renal-transplant recipients in a stable condition, and to determine its risk factors and impact upon allograft function...
  83. ncbi request reprint Long-term evolution of lymphocytes subsets after induction therapy based on continuous versus discontinuous administration of anti-thymocyte globulins in renal-transplant patients
    L Esposito
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    Transplant Proc 37:785-7. 2005
    ..The aim of our retrospective study was to assess the long-term evolution of lymphocyte subsets after two modes of administration of anti-thymocyte globulin (ATG) after renal transplantation...
  84. ncbi request reprint [Hepatitis C infection among patients receiving hemodialysis]
    N Kamar
    Service de Nephrologie, Dialyse et Transplantation, CHU Toulouse Rangueil, Toulouse
    Nephrologie 24:133-41. 2003
    ..Finally, in chronic hemodialysis who are not candidate for renal transplantation IFN-alpha therapy can be discussed according the patients' age and general health status...
  85. doi request reprint Pharmacodynamic effects of everolimus on anti-CD3 antibody-stimulated T-lymphocyte proliferation and interleukin-10 synthesis in stable kidney-transplant patients
    Torsten Bohler
    INSERM U858, I2MR, Eq 10, Institut Louis Bugnard, Batiment L3, CHU Rangueil, 1 avenue J Poulhes, 31403 Toulouse Cedex 4, France
    Cytokine 42:306-11. 2008
    ..In vitro, everolimus inhibited lymphocyte proliferation and IL-10 synthesis dose dependently in anti-CD3 mAb and LPS stimulated peripheral blood mononuclear cell cultures derived from human volunteers...
  86. ncbi request reprint Evidence that clearance of hepatitis C virus RNA after alpha-interferon therapy in dialysis patients is sustained after renal transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse, France
    J Am Soc Nephrol 14:2092-8. 2003
    ..In conclusion, hemodialysis patients waiting for a RT need to be treated with alpha-IFN because when HCV RNA clearance occurred, they experienced no relapse after transplantation despite chronic immunosuppressive treatment...
  87. ncbi request reprint Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans
    Torsten Bohler
    INSERM U466, Institut Louis Bugnard, Toulouse, France
    Ther Drug Monit 29:77-86. 2007
    ..We conclude that these biomarkers used in whole-blood assays are suitable for PD of immune modulators in clinical trials...
  88. ncbi request reprint Ribavirin pharmacokinetics in renal and liver transplant patients: evidence that it depends on renal function
    Nassim Kamar
    Department of Nephrology, Dialysis and Transplantation, CHU Rangueil, Toulouse, France
    Am J Kidney Dis 43:140-6. 2004
    ..Ribavirin is approved for the treatment of chronic hepatitis C virus (HCV) infection. However, no recommendation exists for dosing patients with impaired renal function...
  89. doi request reprint Pharmacodynamic monitoring of the conversion from mycophenolate mofetil to enteric-coated mycophenolate sodium in stable kidney-allograft recipients
    Torsten Bohler
    INSERM U858, Equipe 10, IFR 31, Institut Louis Bugnard, Batiment L3, CHU Rangueil, France
    Int Immunopharmacol 8:769-73. 2008
    ....
  90. doi request reprint Polyoma BK virus-associated nephropathy in kidney-transplant patients: Effects of leflunomide on T-cell functions and disease outcome
    Cindy Canivet
    INSERM U MR, Toulouse, France
    Int Immunopharmacol 9:1131-6. 2009
    ..The aim of this study was to assess i) T-cell functions before and after conversion from MMF to leflunomide in kidney-transplant patients with PVAN, and ii) effects of leflunomide on PVAN outcome...
  91. ncbi request reprint Natural history of hepatitis C virus-related liver fibrosis after renal transplantation
    Nassim Kamar
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, Paris, France
    Am J Transplant 5:1704-12. 2005
    ..The diversification of the HVR-1 might be used to predict liver fibrosis outcome...
  92. ncbi request reprint Factors accelerating liver fibrosis progression in renal transplant patients receiving ribavirin monotherapy for chronic hepatitis C
    Nassim Kamar
    Department of Virology, CHU Purpan, Toulouse, France
    J Med Virol 76:61-8. 2005
    ..Severe chronic hemolysis is responsible for iron overload, liver iron deposition, and an acceleration in the progression of liver fibrosis...
  93. ncbi request reprint Rituximab therapy for de novo mixed cryoglobulinemia in renal transplant patients
    Grégoire Basse
    Multiorgan Transplant Unit, University Hospital, CHU Rangueil, Toulouse, France
    Transplantation 80:1560-4. 2005
    ..e., rituximab). Thus, this provides the rationale to use rituximab for cryoglobulin-related graft dysfunction in RT patients...
  94. doi request reprint Cytomegalovirus prophylaxis with valganciclovir in cytomegalovirus-seropositive kidney-transplant patients
    Hugo Weclawiak
    Department of Nephrology, Dialysis and Multiorgan Transplantation, CHU Rangueil, Toulouse, France
    J Med Virol 80:1228-32. 2008
    ..5% (n=12) of patients, of whom two had two or more consecutive HCMV DNAemias. Valganciclovir prophylaxis in HCMV-seropositive kidney-transplant patients is effective for preventing cytomegalovirus disease...
  95. ncbi request reprint Alpha-interferon therapy for chronic hepatitis C may induce acute allograft rejection in kidney transplant patients with failed allografts
    Hugo Wéclawiack
    Department of Nephrology, CHU Rangueil, 1 av Jean Poulhes, 31059, Toulouse Cedex 9, France
    Nephrol Dial Transplant 23:1043-7. 2008
    ..Conversely, if these HCV(+) KT patients lose their allograft, re-transplantation might be contemplated provided alphaIFN therapy has been attempted...
  96. ncbi request reprint Treatment of hepatitis C virus infection (HCV) after renal transplantation: implications for HCV-positive dialysis patients awaiting a kidney transplant
    Nassim Kamar
    Multiorgan Transplant Unit, CHU Rangueil, Toulouse, France
    Transplantation 82:853-6. 2006
    ..Finally, when HCV-positive dialysis patients with a sustained virological response undergo successful renal transplantation, very few suffer a virological relapse, thus emphasizing that these patients were cured...
  97. ncbi request reprint Twenty-four hour kinetics of hepatitis C virus and antiviral effect of alpha-interferon
    Anne Boulestin
    Laboratoire de Virologie EA 2046 IFR30, CHU Purpan, Toulouse, France
    J Med Virol 78:365-71. 2006
    ..Resistant HCV strains could be distinguished from sensitive viruses as early as a few hours after the beginning of the treatment...
  98. ncbi request reprint [Efficiency of rituximab treatment for recurrence of membranous glomerulopathy after renal transplantation]
    Hugo Weclawiak
    Department de Nephrologie, Dialyse et Transplantation d organes, CHU de Rangueil, 1, avenue Jean Poulhes, TSA 50032 Toulouse cedex 09, France
    Nephrol Ther 3:65-8. 2007
    ..These data may explain the efficiency of rituximab in these circumstances...
  99. ncbi request reprint Evaluation of the efficacy and safety of a slow conversion from calcineurin inhibitor- to sirolimus-based therapies in maintenance renal-transplant patients presenting with moderate renal insufficiency
    Nassim Kamar
    Department of Nephrology Transplantation, Hopital Rangueil, Toulouse, France
    Transpl Int 20:128-34. 2007
    ..Overall, there was a significant increase in proteinuria from 0 (0-3.15) to 0.57 (0-4.85) g/day (P=0.002). Finally, the conversion was associated with a significant increase in lipids, and a significant decrease in hemoglobin levels...