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Genomes and Genes | M KalamaridesSummaryCountry: France Publications
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Publications
[Meningiomas]Michel Kalamarides
Service de Neurochirurgie, Hopital Beaujon, 92110 Clichy
Rev Prat 56:1792-8. 2006..Most meningiomas have good long-term prognosis after treatment, some dysplay aggressive clinical behaviour leading to increased patient morbidity and mortality...
Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutationsMichel Kalamarides
INSERM U674, Paris, France
Brain Pathol 18:62-70. 2008....- Long-term follow-up of 287 meningiomas in neurofibromatosis type 2 patients: clinical, radiological, and molecular featuresStéphane Goutagny
Department of Neurosurgery, Neurofibromatosis type 2 clinic, Hopital Beaujon, Assistance Publique Hopitaux de Paris, Clichy, France
Neuro Oncol 14:1090-6. 2012..Future clinical trials in NF2 need to focus specifically on meningiomas as the primary endpoint and should include patients with meningiomas growing 20% or more per year in order to assess new treatments... - Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meetingMichel Kalamarides
Hopital Beaujon, INSERM U674, Universite Paris 7, Paris, France
Acta Neuropathol 123:369-80. 2012.... 
Meningioma mouse modelsMichel Kalamarides
Department of Neurosurgery, APHP, Hopital Beaujon, Service de Neurochirurgie, 100 Bvd Du General Leclerc, Clichy, France
J Neurooncol 99:325-31. 2010..We present here a review of current meningioma mouse models used in translational therapeutics with associated imaging and pre-clinical studies...- [Creation of self-assessment tools for on-line continuing medical education. Modelization of a training session]M Kalamarides
Service de Neurochirurgie, Hopital Beaujon, AP HP, Faculté de Médecine Paris 7, 100, boulevard Général Leclerc, 92110 Clichy, France
Neurochirurgie 54:21-7. 2008.... - Extraaxial primitive neuroectodermal tumor mimicking a vestibular schwannoma: diagnostic and therapeutic difficulties. Report of two casesM Kalamarides
Department of Neurosurgery, H pital Beaujon, Assistance Publique H pitaux de Paris, Faculte X Bichat, Universite Paris, Clichy, France
J Neurosurg 94:612-6. 2001..A CPA PNET mimicking a VS is a rare entity, the diagnosis of which is important because its treatment differs dramatically from that of VS, including prescribed surgery followed by conventional craniospinal radiotherapy... - [Small acoustic neuroma: observation or treatment? A review of 207 cases]M Kalamarides
Service de Neurochirurgie, Universite Paris, France
Neurochirurgie 47:403-12. 2001.... - Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypesM Kalamarides
INSERM, U674, Paris, France
Oncogene 30:2333-44. 2011..Collectively, these findings establish the cell of origin for these common brain tumours as well as a susceptible developmental period in which signature genetic mutations culminate in meningioma formation... - Hearing restoration with auditory brainstem implants after radiosurgery for neurofibromatosis type 2M Kalamarides
Department of Neurosurgery and Otolaryngology, Hopital Beaujon, Faculte Xavier Bichat, Universite Paris 7, France
J Neurosurg 95:1028-33. 2001..It is concluded that hearing function can be rehabilitated using ABIs in patients with NF2, even if radiosurgery fails to control the tumor growth... - Four-channel electromyography of the facial nerve in vestibular schwannoma surgery: sensitivity and prognostic value for short-term facial function outcomeAlexis Bozorg Grayeli
Otolaryngology Department, , Clichy, France
Otol Neurotol 26:114-20. 2005..CONCLUSION: A four-channel device may enhance electromyographic sensitivity. Determination of stimulation threshold below 0.05 mA yields facial prognostic information... - Intraoperative electromyography and surgical observations as predictive factors of facial nerve outcome in vestibular schwannoma surgeryIsabelle Bernat
AP HP, Hopital Beaujon, Otolaryngology Department, Clichy, France
Otol Neurotol 31:306-12. 2010..To evaluate the predictive value of electromyographic recordings for the immediate facial nerve outcome after solitary vestibular schwannoma (VS) removal... - Use of anatomic or invasive markers in association with skin surface registration in image-guided surgery of the temporal boneAlexis Bozorg Grayeli
Otolaryngology Department, AP HP, Beaujon Hospital, Clichy, France
Acta Otolaryngol 129:405-10. 2009..The use of an invasive marker in the ipsilateral temporal bone with mid-facial skin contouring for registration improved the position accuracy (PA) to levels required for otological and neuro-otological procedures... - Auditory brainstem implant in neurofibromatosis type 2 and non-neurofibromatosis type 2 patientsAlexis Bozorg Grayeli
Department of Otolaryngology, AP HP, Hopital Beaujon, Clichy, France
Otol Neurotol 29:1140-6. 2008..To evaluate the auditory brainstem implant (ABI) performances in neurofibromatosis type 2 (NF2) and non-NF2 patients... - Diagnostic value of auditory brainstem responses in cerebellopontine angle tumoursAlexis Bozorg Grayeli
Otolaryngology Department, AP HP, Hopital Beaujon, Clichy, France
Acta Otolaryngol 128:1096-100. 2008..Auditory brainstem responses (ABRs) associated with other audio-vestibular examinations and a thorough clinical examination should allow detection of the majority of cerebellopontine angle (CPA) lesions (99.2-100%)... - Diagnosis and management of intracochlear schwannomasAlexis Bozorg Grayeli
Department of Otolaryngology Head and Neck Surgery, AP HP, Beaujon Hospital, Clichy, France
Otol Neurotol 28:951-7. 2007..To describe and analyze a series of intracochlear schwannomas... - Auditory brainstem implantation to rehabilitate profound hearing loss with totally ossified cochleae induced by pneumococcal meningitisAlexis Bozorg Grayeli
Department of Otolaryngology, Head and Neck Surgery, Hopital Beaujon, Clichy, France
Audiol Neurootol 12:27-30. 2007..Auditory brainstem implants are an efficient means of auditory rehabilitation and may be considered in selected cases of bilateral profound hearing loss with the impossibility of cochlear implantation... - Intratumoral and brainstem hemorrhage in a patient with vestibular schwannoma and oral anticoagulant therapyJean Francois Vellin
Department of Otolaryngology, Hopital Beaujon, AP HP, Clichy, France
Otol Neurotol 27:209-12. 2006..To report the first case of spontaneous intratumoral and brainstem hemorrhage in a patient with a vestibular schwannoma... - Optimization of bacterial diagnosis yield after needle aspiration in immunocompetent adults with brain abscessesVictoire de Lastours
Internal Medicine Department, Beaujon Hospital, Assistance Publique Hopitaux de Paris, Clichy, France
Neurosurgery 63:362-7; discussion 367-8. 2008..Our purpose was to evaluate the efficacy of a strategy aimed at obtaining a microbiological diagnosis in immunocompetent patients presenting with suspected BAs... - Conservative management versus surgery for small vestibular schwannomasAlexis Bozorg Grayeli
Department of Otolaryngology Head and Neck Surgery, Hopital Beaujon, Clichy, France
Acta Otolaryngol 125:1063-8. 2005..Of the conservative management group, 17% were lost during follow-up. After surgery, grade 1 or 2 facial function was obtained in 86% of cases. Following hearing preservation attempts (n=137), 54% of patients were in hearing classes A-C... - Opening cerebrospinal fluid pressure guides the management of cerebrospinal fluid leakage after acoustic neuroma surgeryMichel Kalamarides
Neurosurgery Department, Hopital Beaujon, AP HP, Clichy, France
Otol Neurotol 25:769-72. 2004..To assess the value of cerebrospinal fluid pressure as a decisional factor for immediate surgical revision in cerebrospinal fluid leakage after acoustic neuroma removal... - Do facial nerve displacement pattern and tumor adhesion influence the facial nerve outcome in vestibular schwannoma surgery?Gonzalo N Esquia-Medina
Otolaryngology Head and Neck Surgery Department, AP HP, Beaujon Hospital, Clichy, France
Otol Neurotol 30:392-7. 2009..To assess the nerve facial displacement by a vestibular schwannoma and nerve adhesion to tumor as predictive factors of facial function outcome... - [Neurofibromatosis type 2]S Goutagny
Service de Neurochirurgie, Service d ORL, Hopital Beaujon, APHP, 100 Boulevard du General Leclerc, 92118 Clichy
Rev Neurol (Paris) 163:765-77. 2007..Neurofibromatosis 2 (NF2) is a rare autosomal dominant disease whose hallmark is the development of bilateral vestibular schwannomas... - Merlin regulates transmembrane receptor accumulation and signaling at the plasma membrane in primary mouse Schwann cells and in human schwannomasD Lallemand
INSERM, U674, Paris, France
Oncogene 28:854-65. 2009.... - Comparison between intraoperative observations and electromyographic monitoring data for facial nerve outcome after vestibular schwannoma surgeryAlexis Bozorg Grayeli
Department of Neurosurgery, , Clichy, France
Acta Otolaryngol 125:1069-74. 2005..The maximal EMG response was detected in the frontal or platysma muscles in 26% of cases, and in the orbicularis oris and orbicularis oculi muscles in 74%... - Evaluation of the management of postoperative aseptic meningitisVirginie Zarrouk
Department of Internal Medicine, Beaujon Hospital, Assistance Publique Hopitaux de Paris, Clichy, France
Clin Infect Dis 44:1555-9. 2007..However, this approach is not universally accepted and has not been assessed in clinical trials... - Clinical epidemiology for childhood primary central nervous system tumorsLuc Bauchet
Department of Neurosurgery, Centre Hospitalo Universitaire, Hopital Gui de Chauliac, 80 avenue Augustin Fliche, 34 295, Montpellier Cedex 5, France
J Neurooncol 92:87-98. 2009.... - Increased growth rate of vestibular schwannoma after resection of contralateral tumor in neurofibromatosis type 2Matthieu Peyre
Service de Neurochirurgie, Assistance Publique Hopitaux de Paris, Hopital Beaujon, Clichy, France
Neuro Oncol 13:1125-32. 2011..This possibility should be integrated in NF2 patient management to adequately treat the second VS... - Broad-range 16S rRNA PCR with cerebrospinal fluid may be unreliable for management of postoperative aseptic meningitisVirginie Zarrouk
Department of Internal Medicine, Hopital Beaujon, 100, boulevard du General Leclerc, 92110 Clichy, France
J Clin Microbiol 48:3331-3. 2010..All 26 patients with PAM diagnosed on the basis of conventional cultures demonstrated negative 16S rRNA PCR results. Our results suggest that the PCR technique does not change PAM management... - Cervical dumbbell intra-extradural hemangioblastoma: total removal through the lateral approach: technical case reportCédric Barrey
Department of Neurosurgery, Hôpital Neurologique P Wertheimer, Lyon, France
Neurosurgery 56:E625; discussion E625. 2005..Among them, intra-extradural forms with a dumbbell extension are extremely rare. We report a case of intra-extradural hemangioblastoma involving the C6 cervical nerve root... - Auditory brainstem implant in bilateral and completely ossified cochleaeAlexis Bozorg Grayeli
Department of Otolaryngology Head and Neck Surgery, Hôpital Beaujon AP HP and Faculté Xavier Bichat, INSERM, Universite Paris, France
Otol Neurotol 24:79-82. 2003..To report and evaluate the results of auditory brainstem implantation in a case of postmeningitis hearing loss with totally ossified cochleae on both sides... - Nf2 gene inactivation in arachnoidal cells is rate-limiting for meningioma development in the mouseMichel Kalamarides
INSERM U434, Fondation Jean Dausset Centre d Etude du Polymorphisme Humain, 75010 Paris, France
Genes Dev 16:1060-5. 2002..This first mouse model initiated with a genetic lesion found in human meningiomas provides a powerful tool for investigating tumor progression and for the preclinical evaluation of therapeutic interventions... - [Lipomatous meningioma: two case reports]Taoufiq Harmouch
Service d'Anatomie et de Cytologie Pathologiques, , , 92118 Clichy Cedex
Ann Pathol 25:389-92. 2005..These immunohistochemical results suggest that lipid accumulation in meningioma should be considered a transformation of meningothelial cells rather than a true metaplasia...