- Joutel A, Tournier Lasserve E. [Molecular basis and physiopathogenic mechanisms of CADASIL: a model of small vessel diseases of the brain]. J Soc Biol. 2002;196:109-15 pubmed..Furthermore, they open new perspectives in the field of small-artery diseases of the brain and should help to further dissect their genetic etiologies and understand their pathogenic mechanisms. ..
- Joutel A, Monet M, Domenga V, Riant F, Tournier Lasserve E. Pathogenic mutations associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy differently affect Jagged1 binding and Notch3 activity via the RBP/JK signaling Pathway. Am J Hum Genet. 2004;74:338-47 pubmed..We conclude that mutations in Notch3 differently affect Jagged1 binding and Notch3 signaling via the RBP/JK pathway. ..