Research Topics
Species | F JollantSummaryCountry: France Publications
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Publications
The influence of four serotonin-related genes on decision-making in suicide attemptersFabrice Jollant
Universite Montpellier 1, Montpellier, France
Am J Med Genet B Neuropsychiatr Genet 144:615-24. 2007..We hypothesize that the influence of genetic factors on the vulnerability to suicidal behavior may partly be achieved through their modulation of decision-making and particularly its learning component...
[Severe depression : functional neuroanatomy]F Jollant
Hopital Lapeyronie, Service de Psychologie Médicale et Psychiatrie Pr Ph Courtet, 371 av Doyen G Giraud 34295 Montpellier cedex 5, Universite Montpellier, INSERM U888
Encephale 35:S301-5. 2009..These findings open the door to new treatments...- Orbitofrontal cortex response to angry faces in men with histories of suicide attemptsFabrice Jollant
Universite Montpellier I, Institut National de la Santé et de la Recherche Médicale U 888, Centre Hospitalier Universitaire, Montpellier, France
Am J Psychiatry 165:740-8. 2008..The authors sought to elucidate the functional neural basis of the neurobiological abnormalities underlying the vulnerability to suicidal behavior... - Psychiatric diagnoses and personality traits associated with disadvantageous decision-makingF Jollant
Universite Montpellier 1, Faculte de Medecine, Montpellier, F 34000, France
Eur Psychiatry 22:455-61. 2007..Decision-making impairment is an important feature of psychiatric disorders. In a large comorbid psychiatric population, we explored the link between decision-making deficit and clinical variables... - Impaired decision-making in suicide attempters may increase the risk of problems in affective relationshipsFabrice Jollant
Universite Montpellier 1, Montpellier, F 34000 France
J Affect Disord 99:59-62. 2007..In the present study, we hypothesized that impaired decision-making may be associated with an increased risk of negative life events in suicide attempters... - Serotonin transporter gene may be involved in short-term risk of subsequent suicide attemptsPhilippe Courtet
Department of Psychological Medicine and Psychiatry, Lapeyronie Hospital, Montpellier, France
Biol Psychiatry 55:46-51. 2004..We aim to determine the predictive value of two serotonin-related genes, the tryptophan hydroxylase (TPH) and serotonin transporter (5-HTTLPR) genes that have been involved in the susceptibility to suicidal behavior... - Genes, suicide and decisionsP Courtet
University Montpellier I, 34000 Montpellier, France
Eur Psychiatry 25:294-6. 2010..The vulnerability to SB appears to be underlied by genetic factors coding for traits rendering the individual less able to cope with stressing situations, and more likely to be engaged in a suicidal process... - [Implication of genes of the serotonergic system on vulnerability to suicidal behavior]Philippe Courtet
Service de Psychologie médicale et Psychiatrie, Hopital Lapeyronie, Centre Hospitalier Universitaire de Montpellier 34295 Cedex 5 Montpellier, France
J Psychiatry Neurosci 29:350-9. 2004..Current studies aim to identify either the precise phenotypes associated with genes for vulnerability to suicidal behaviour or the intermediate phenotypes (e.g., impulsivity, anger dyscontrol) associated with these genes... - The monoamine oxidase A gene may influence the means used in suicide attemptsPhilippe Courtet
Department of Psychological Medicine and Psychiatry, Lapeyronie Hospital, Montpellier Cedex, France
Psychiatr Genet 15:189-93. 2005..The aim of the study was to investigate, in a large sample, whether the monoamine oxidase A gene was involved in the susceptibility to suicidal behavior... - Somatic markers and explicit knowledge are both involved in decision-makingSebastien Guillaume
University of Montpellier, Montpellier, France
Neuropsychologia 47:2120-4. 2009..Advantageous decision-making therefore seems to be associated with two distinct, namely implicit and explicit, systems... - Suicidal behavior: relationship between phenotype and serotonergic genotypePhilippe Courtet
Service de Psychologie Médicale and Psychiatrie, Hopital Lapeyronie, Montpellier, France
Am J Med Genet C Semin Med Genet 133:25-33. 2005..One of the main aims of studies currently underway is to identify the precise phenotypes associated with genes that predispose to SB or intermediate phenotypes (impulsivity, inability to control anger, etc.)... - The neuroscience of suicidal behaviors: what can we expect from endophenotype strategies?P Courtet
Department of Emergency Psychiatry, CHRU Montpellier, Inserm U1061, University of Montpellier I, Montpellier, France
Transl Psychiatry 1:e7. 2011..Specific endophenotypes may represent heritable markers for the identification of vulnerable patients and may be relevant targets for successful suicide prevention and treatments... - The need to consider mood disorders, and especially chronic mania, in cases of Diogenes syndrome (squalor syndrome)G Fond
University of Montpellier, Montpellier, France
Int Psychogeriatr 23:505-7. 2011..Mood disorders - in particular chronic mania (i.e. a manic episode lasting more than two years) - should be considered in cases of Diogenes syndrome and in current classifications... - Higher psychological pain during a major depressive episode may be a factor of vulnerability to suicidal ideation and actEmilie Olie
Universite Montpellier 1, Montpellier, France
J Affect Disord 120:226-30. 2010..In addition, suicidal acts may be best understood within a stress-vulnerability model. We hypothesized that more intense psychache during a major depressive episode would be a factor of vulnerability to suicidal behavior... - Catechol-O-methyltransferase polymorphism (COMT) in suicide attempters: a possible gender effect on anger traitsPatrick Baud
Department of Psychiatry, University Hospital of Geneva, Geneva, Switzerland
Am J Med Genet B Neuropsychiatr Genet 144:1042-7. 2007..These results are discussed in the light of recently published data on the effect of COMT Val158Met polymorphism on different cognitive and behavioral traits... - Impaired decision making in suicide attemptersFabrice Jollant
Department of Psychological Medicine and Psychiatry, Lapeyronie Hospital, , E 0361, France
Am J Psychiatry 162:304-10. 2005..CONCLUSIONS: Impaired decision making, possibly due to emotional dysfunction, may be a neuropsychological risk factor for suicidal behavior... - Prefrontal cortex dysfunction in patients with suicidal behaviorAurelie Raust
Department of Psychiatry, Chenevier Mondor Hospital, Assistance Publique Hopitaux de Paris, Creteil Cedex, France
Psychol Med 37:411-9. 2007..We investigated PFC-related neuropsychological function in patients with suicidal behavior, separating dorsolateral PFC (DLPFC)- and orbitofrontal cortex (OFC)-related functions... - No human tryptophan hydroxylase-2 gene R441H mutation in a large cohort of psychiatric patients and control subjectsRichard Delorme
Human Genetics and Cognitive Functions, Pasteur Institute, Paris, France
Biol Psychiatry 60:202-3. 2006..1.4% in control subjects)... - A history of major depressive disorder influences intent to die in violent suicide attemptersBernard Astruc
Department of Psychological Medicine and Psychiatry, Lapeyronie Hospital, CHU Montpellier, France
J Clin Psychiatry 65:690-5. 2004..Our results suggest that biological and genetic studies should take into account the method used to attempt suicide, intent to die, and history of MDD...