- Protein kinase C as a peripheral biomarker for Alzheimer's diseaseJean de Barry
Institut des Neurosciences Cellulaires et Integratives, CNRS, Strasbourg, France
Exp Gerontol 45:64-9. 2010..Such probes can be used to detect PKC alterations in red blood cells and thus to distinguish AD patients from healthy controls with unmatched specificity and sensitivity...
- Alteration of protein kinase C conformation in red blood cells: a potential marker for Alzheimer's disease but not for Parkinson's diseaseAgnes Janoshazi
Neurotransmission et Sécretion Neuroendocrine UPR2356 CNRS, Strasbourg, France
Neurobiol Aging 27:245-51. 2006..If PKC alteration is proven to be specific to AD as compared with other dementia, this method could be for a simple, low cost screening test among patients suspected of having AD and may have a strong predictive value...
- F-actin does not modulate the initial steps of the protein kinase C activation process in living nerve cellsVirginie Geeraert
Neurotransmission et Secretion Neuroendocrine, UPR 2356 CNRS, 5 rue B Pascal, F 67084 Strasbourg CEDEX, France
Exp Cell Res 289:222-36. 2003..These results suggest that the actin network is not involved in the initial steps of the PKC activation process in living nerve cells...
- The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine 2B receptor is a gain of proliferative functionsMaud Deraet
INSERM U616 Hospital Pitié Salpetrière, Bâtiment Pédiatrie, 47 Boulevard de l Hopital, 75651 Paris Cedex 13, France
Mol Pharmacol 67:983-91. 2005..All these modifications are relevant in pathophysiological vasoconstriction...