Caroline Jacques

Summary

Country: France

Publications

  1. ncbi Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors
    Caroline Jacques
    Institut National de la Sante et de la Recherche Medicale, E0018, Laboratoire de Biochimie et Biologie Moleculaire, Centre Hospitalier Universitaire d Angers, 4 rue Larrey, F 49033 Angers, France
    J Clin Endocrinol Metab 90:2314-20. 2005
  2. doi DNA microarray and miRNA analyses reinforce the classification of follicular thyroid tumors
    Caroline Jacques
    Institut National de la Santé et de la Recherche Médicale U694, rue des Capucins, F 49033 Angers, France
    J Clin Endocrinol Metab 98:E981-9. 2013
  3. ncbi PGC-1-related coactivator and targets are upregulated in thyroid oncocytoma
    Frederique Savagner
    INSERM EMI U 00 18, Laboratoire de Biochimie et Biologie Moleculaire, CHU, Angers, France
    Biochem Biophys Res Commun 310:779-84. 2003
  4. pmc Nitric oxide and calcium participate in the fine regulation of mitochondrial biogenesis in follicular thyroid carcinoma cells
    Soazig Le Pennec
    Inserm UMR694, Centre Hospitalier Universitaire d Angers, F 49033 Angers, France
    J Biol Chem 286:18229-39. 2011
  5. ncbi mtDNA controls expression of the Death Associated Protein 3
    Caroline Jacques
    From INSERM, U694, F 49033 Angers, France
    Exp Cell Res 312:737-45. 2006
  6. ncbi Dinitrophenol-induced mitochondrial uncoupling in vivo triggers respiratory adaptation in HepG2 cells
    Valerie Desquiret
    Department of Biochemistry and Molecular Biology, INSERM UMR 694, 4 rue Larrey, F 49033 Angers Cedex, France
    Biochim Biophys Acta 1757:21-30. 2006
  7. doi Modulation of mitochondrial capacity and angiogenesis by red wine polyphenols via estrogen receptor, NADPH oxidase and nitric oxide synthase pathways
    Lucie Duluc
    LUNAM, France, INSERM, U1063, F 49100 Angers, France
    Int J Biochem Cell Biol 45:783-91. 2013
  8. ncbi Structure and chromosomal distribution of human mitochondrial pseudogenes
    Yves Tourmen
    INSERM EMI U 00 18, Laboratoire de Biochimie et Biologie Moleculaire, CHU d Angers, Angers, F 49033, France
    Genomics 80:71-7. 2002

Collaborators

Detail Information

Publications8

  1. ncbi Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumors
    Caroline Jacques
    Institut National de la Sante et de la Recherche Medicale, E0018, Laboratoire de Biochimie et Biologie Moleculaire, Centre Hospitalier Universitaire d Angers, 4 rue Larrey, F 49033 Angers, France
    J Clin Endocrinol Metab 90:2314-20. 2005
    ..Our results show an increased expression of genes involved in protein metabolism in oncocytoma, the significance of which requires investigation...
  2. doi DNA microarray and miRNA analyses reinforce the classification of follicular thyroid tumors
    Caroline Jacques
    Institut National de la Santé et de la Recherche Médicale U694, rue des Capucins, F 49033 Angers, France
    J Clin Endocrinol Metab 98:E981-9. 2013
    ..Focusing on mitochondrial function and thyroid tumorigenesis, we used an integrative approach to identify relevant biomarkers for borderline thyroid lesions...
  3. ncbi PGC-1-related coactivator and targets are upregulated in thyroid oncocytoma
    Frederique Savagner
    INSERM EMI U 00 18, Laboratoire de Biochimie et Biologie Moleculaire, CHU, Angers, France
    Biochem Biophys Res Commun 310:779-84. 2003
    ..However, no mtDNA variant in the D-loop region appeared to be involved in oncocytic development. We conclude that overexpression of the PRC pathway is responsible for mitochondrial proliferation in the context of thyroid oncocytoma...
  4. pmc Nitric oxide and calcium participate in the fine regulation of mitochondrial biogenesis in follicular thyroid carcinoma cells
    Soazig Le Pennec
    Inserm UMR694, Centre Hospitalier Universitaire d Angers, F 49033 Angers, France
    J Biol Chem 286:18229-39. 2011
    ..This is the first demonstration that NO and calcium regulate mitochondrial biogenesis through the PRC pathway in thyroid cell lines...
  5. ncbi mtDNA controls expression of the Death Associated Protein 3
    Caroline Jacques
    From INSERM, U694, F 49033 Angers, France
    Exp Cell Res 312:737-45. 2006
    ..The absence of pro-apoptotic DAP3 in these mtDNA-less cells could explain their reduced apoptotic capacity. Our results suggest that the mtDNA content plays a role in cell apoptosis by mediating the expression of DAP3...
  6. ncbi Dinitrophenol-induced mitochondrial uncoupling in vivo triggers respiratory adaptation in HepG2 cells
    Valerie Desquiret
    Department of Biochemistry and Molecular Biology, INSERM UMR 694, 4 rue Larrey, F 49033 Angers Cedex, France
    Biochim Biophys Acta 1757:21-30. 2006
    ....
  7. doi Modulation of mitochondrial capacity and angiogenesis by red wine polyphenols via estrogen receptor, NADPH oxidase and nitric oxide synthase pathways
    Lucie Duluc
    LUNAM, France, INSERM, U1063, F 49100 Angers, France
    Int J Biochem Cell Biol 45:783-91. 2013
    ..These results suggest a possible association between the modulation of mitochondrial capacity by LCP and its pro-angiogenic activity. These data provide evidence for a role of mitochondria in the regulation of angiogenesis by RWPC...
  8. ncbi Structure and chromosomal distribution of human mitochondrial pseudogenes
    Yves Tourmen
    INSERM EMI U 00 18, Laboratoire de Biochimie et Biologie Moleculaire, CHU d Angers, Angers, F 49033, France
    Genomics 80:71-7. 2002
    ..Thus, these pseudogenes should be very useful in the study of ancient mtDNA and nuclear genome evolution...