Research Topics
Species | Caroline JacquesSummaryCountry: France Publications
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Publications
Two-step differential expression analysis reveals a new set of genes involved in thyroid oncocytic tumorsCaroline Jacques
Institut National de la Sante et de la Recherche Medicale, E0018, Laboratoire de Biochimie et Biologie Moleculaire, Centre Hospitalier Universitaire d Angers, 4 rue Larrey, F 49033 Angers, France
J Clin Endocrinol Metab 90:2314-20. 2005..Our results show an increased expression of genes involved in protein metabolism in oncocytoma, the significance of which requires investigation...
PGC-1-related coactivator and targets are upregulated in thyroid oncocytomaFrederique Savagner
INSERM EMI U 00 18, Laboratoire de Biochimie et Biologie Moleculaire, CHU, Angers, France
Biochem Biophys Res Commun 310:779-84. 2003..However, no mtDNA variant in the D-loop region appeared to be involved in oncocytic development. We conclude that overexpression of the PRC pathway is responsible for mitochondrial proliferation in the context of thyroid oncocytoma...
Nitric oxide and calcium participate in the fine regulation of mitochondrial biogenesis in follicular thyroid carcinoma cellsSoazig Le Pennec
Inserm UMR694, Centre Hospitalier Universitaire d Angers, F 49033 Angers, France
J Biol Chem 286:18229-39. 2011..This is the first demonstration that NO and calcium regulate mitochondrial biogenesis through the PRC pathway in thyroid cell lines...
mtDNA controls expression of the Death Associated Protein 3Caroline Jacques
From INSERM, U694, F 49033 Angers, France
Exp Cell Res 312:737-45. 2006..The absence of pro-apoptotic DAP3 in these mtDNA-less cells could explain their reduced apoptotic capacity. Our results suggest that the mtDNA content plays a role in cell apoptosis by mediating the expression of DAP3...
Dinitrophenol-induced mitochondrial uncoupling in vivo triggers respiratory adaptation in HepG2 cellsValerie Desquiret
Department of Biochemistry and Molecular Biology, INSERM UMR 694, 4 rue Larrey, F 49033 Angers Cedex, France
Biochim Biophys Acta 1757:21-30. 2006....
Structure and chromosomal distribution of human mitochondrial pseudogenesYves Tourmen
INSERM EMI U 00 18, Laboratoire de Biochimie et Biologie Moleculaire, CHU d Angers, Angers, F 49033, France
Genomics 80:71-7. 2002..Thus, these pseudogenes should be very useful in the study of ancient mtDNA and nuclear genome evolution...
