E Jacquemin

Summary

Country: France

Publications

  1. ncbi The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood
    E Jacquemin
    Hepatology Unit, Department of Pediatrics, and INSERM U 347, Hopital de Bicetre, Le Kremlin Bicetre, France
    Gastroenterology 120:1448-58. 2001
  2. ncbi Progressive familial intrahepatic cholestasis
    E Jacquemin
    Department of Pediatrics and INSERM U 347, Bicetre Hospital, Le Kremlin Bicetre, France
    J Gastroenterol Hepatol 14:594-9. 1999
  3. ncbi Progressive familial intrahepatic cholestasis. Genetic basis and treatment
    E Jacquemin
    Hepatology Unit, Department of Pediatrics, and INSERM U347, University of Paris Sud School of Medicine, Hopital de Bicetre, Le Kremlin Bicetre, France
    Clin Liver Dis 4:753-63. 2000
  4. ncbi Genetic cholestatic liver diseases: the example of progressive familial intrahepatic cholestasis and related disorders
    C Baussan
    Biochemistry 1 Unit, Bicetre University Hospital, Le Kremlin Bicetre, France
    Acta Gastroenterol Belg 67:179-83. 2004
  5. doi Congenital portosystemic shunts in children: recognition, evaluation, and management
    O Bernard
    hépatologie pédiatrique, Hopital Bicetre, AP HP, Universite Paris Sud, Le Kremlin Bicetre, France
    Semin Liver Dis 32:273-87. 2012
  6. ncbi Role of multidrug resistance 3 deficiency in pediatric and adult liver disease: one gene for three diseases
    E Jacquemin
    Hepatology Unit, Department of Pediatrics, and INSERM U 347, Centre Hospitalier Universitaire de Bicetre, Paris, France
    Semin Liver Dis 21:551-62. 2001
  7. ncbi Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy
    E Jacquemin
    Lancet 353:210-1. 1999
  8. ncbi Liver cell adenomas and portosystemic shunt
    V Dhalluin-Venier
    Service des maladies du foie et de l appareil digestif, CHU Bicetre, 78, rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Gastroenterol Clin Biol 32:164-6. 2008
  9. ncbi [Recommendations of the French Hepatology, Gastroenterology and Pediatric Nutrition Group. Current indications for digestive system endoscopy in children]
    J F Mougenot
    Service de Gastroentérologie pédiatrique, Hopital Robert Debre, 48, boulevard Serurier, 75935 Paris, France
    Arch Pediatr 9:942-4. 2002
  10. ncbi Respiratory chain deficiency in Alpers syndrome
    M Gauthier-Villars
    Department of Medical Genetics and INSERM U-393, , Paris, France
    Neuropediatrics 32:150-2. 2001

Collaborators

  • O Bernard
  • M Paul
  • J F Mougenot
  • Efienne M Sokal
  • M Hadchouel
  • P L Jansen
  • V Dhalluin-Venier
  • C Baussan
  • D Cresteil
  • M Gauthier-Villars
  • G Pelletier
  • C Buffet
  • A S Rangheard
  • M Fabre
  • J M de Vree
  • E Gonzales
  • N Raynaud
  • M Dumont
  • P Rustin
  • A Munnich
  • P de Lonlay
  • V Cormier-Daire
  • P Landrieu
  • M Burdelski
  • J F Deleuze
  • J Aten
  • E Sturm
  • R P Oude Elferink
  • M Desrochers
  • P J Bosma

Detail Information

Publications12

  1. ncbi The wide spectrum of multidrug resistance 3 deficiency: from neonatal cholestasis to cirrhosis of adulthood
    E Jacquemin
    Hepatology Unit, Department of Pediatrics, and INSERM U 347, Hopital de Bicetre, Le Kremlin Bicetre, France
    Gastroenterology 120:1448-58. 2001
    ..We have specified the features of progressive familial intrahepatic cholestasis type 3 and investigated in 31 patients whether a defect of the multidrug resistance 3 gene (MDR3) underlies this phenotype...
  2. ncbi Progressive familial intrahepatic cholestasis
    E Jacquemin
    Department of Pediatrics and INSERM U 347, Bicetre Hospital, Le Kremlin Bicetre, France
    J Gastroenterol Hepatol 14:594-9. 1999
    ..In the future, other therapies, such as cell and gene therapies, might be considered and could also represent an alternative to liver transplantation...
  3. ncbi Progressive familial intrahepatic cholestasis. Genetic basis and treatment
    E Jacquemin
    Hepatology Unit, Department of Pediatrics, and INSERM U347, University of Paris Sud School of Medicine, Hopital de Bicetre, Le Kremlin Bicetre, France
    Clin Liver Dis 4:753-63. 2000
    ....
  4. ncbi Genetic cholestatic liver diseases: the example of progressive familial intrahepatic cholestasis and related disorders
    C Baussan
    Biochemistry 1 Unit, Bicetre University Hospital, Le Kremlin Bicetre, France
    Acta Gastroenterol Belg 67:179-83. 2004
  5. doi Congenital portosystemic shunts in children: recognition, evaluation, and management
    O Bernard
    hépatologie pédiatrique, Hopital Bicetre, AP HP, Universite Paris Sud, Le Kremlin Bicetre, France
    Semin Liver Dis 32:273-87. 2012
    ..This leaves little or no place for liver transplantation in the management of these children...
  6. ncbi Role of multidrug resistance 3 deficiency in pediatric and adult liver disease: one gene for three diseases
    E Jacquemin
    Hepatology Unit, Department of Pediatrics, and INSERM U 347, Centre Hospitalier Universitaire de Bicetre, Paris, France
    Semin Liver Dis 21:551-62. 2001
    ..Therefore, at least three human liver diseases are due to a single gene deficiency. Patients with PFIC3 due to MDR3 deficiency may benefit from ursodeoxycholic acid therapy and could be good candidates for cell therapy in the future...
  7. ncbi Heterozygous non-sense mutation of the MDR3 gene in familial intrahepatic cholestasis of pregnancy
    E Jacquemin
    Lancet 353:210-1. 1999
  8. ncbi Liver cell adenomas and portosystemic shunt
    V Dhalluin-Venier
    Service des maladies du foie et de l appareil digestif, CHU Bicetre, 78, rue du General Leclerc, 94270 Le Kremlin Bicetre, France
    Gastroenterol Clin Biol 32:164-6. 2008
    ..Our patient had no known risk factors for liver cell adenomas. We discuss the hypothesis that disturbed hepatic vascularisation could promote the development of liver cell adenomas...
  9. ncbi [Recommendations of the French Hepatology, Gastroenterology and Pediatric Nutrition Group. Current indications for digestive system endoscopy in children]
    J F Mougenot
    Service de Gastroentérologie pédiatrique, Hopital Robert Debre, 48, boulevard Serurier, 75935 Paris, France
    Arch Pediatr 9:942-4. 2002
  10. ncbi Respiratory chain deficiency in Alpers syndrome
    M Gauthier-Villars
    Department of Medical Genetics and INSERM U-393, , Paris, France
    Neuropediatrics 32:150-2. 2001
    ....
  11. ncbi Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis
    P L Jansen
    Department of Gastroenterology, University Hospital Groningen, Groningen, The Netherlands
    Gastroenterology 117:1370-9. 1999
    ..We investigated expression of the bile salt export pump (BSEP) in liver samples from patients with a PFIC phenotype and correlated this with BSEP gene mutations...
  12. pmc Mutations in the MDR3 gene cause progressive familial intrahepatic cholestasis
    J M de Vree
    Department of Gastroenterology and Liver Diseases, Academic Medical Center F 0 116, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Proc Natl Acad Sci U S A 95:282-7. 1998
    ..The histopathological picture in these patients is very similar to that in the corresponding mdr2(-/-) mouse, in which mdr2 P-gp deficiency induces complete absence of phospholipid in bile...