Florence Le Calvez-Kelm

Summary

Affiliation: International Agency for Research on Cancer
Country: France

Publications

  1. pmc MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells
    Maria Ouzounova
    Epigenetics Group, International Agency for Research on Cancer IARC, 150 rue Albert Thomas, Lyon, 69008, France
    BMC Genomics 14:139. 2013
  2. pmc Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study
    Florence Le Calvez-Kelm
    International Agency for Research on Cancer, 150 cours Albert Thomas, Lyon Cedex 08, F 69372, France
    Breast Cancer Res 13:R6. 2011
  3. pmc Detecting differential allelic expression using high-resolution melting curve analysis: application to the breast cancer susceptibility gene CHEK2
    Tú Nguyen-Dumont
    Genetic Cancer Susceptibility Group, IARC, 69372 Lyon, France
    BMC Med Genomics 4:39. 2011
  4. pmc Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the TP53 locus
    Sonia Garritano
    Department of Biology, Genetics via Derna 1, University of Pisa, Pisa, Italy
    BMC Genet 10:5. 2009
  5. pmc RAD51 and breast cancer susceptibility: no evidence for rare variant association in the Breast Cancer Family Registry study
    Florence Le Calvez-Kelm
    Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, France
    PLoS ONE 7:e52374. 2012
  6. ncbi request reprint Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells
    Hector Hernandez-Vargas
    Epigenetics Group, International Agency for Research on Cancer, Lyon, France
    Epigenetics 6:428-39. 2011
  7. doi request reprint Identification of a DNA methylome signature of esophageal squamous cell carcinoma and potential epigenetic biomarkers
    Sheila C S Lima
    International Agency for Research on Cancer, Lyon, France
    Epigenetics 6:1217-27. 2011
  8. pmc Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer
    Sean V Tavtigian
    International Agency for Research on Cancer, 69372 Lyon, France
    Am J Hum Genet 85:427-46. 2009
  9. pmc Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples
    Elodie Caboux
    Laboratory Services and Biobank, International Agency for Research on Cancer, Lyon, France
    PLoS ONE 8:e79826. 2013
  10. pmc Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors
    Hector Hernandez-Vargas
    Epigenetics Group, International Agency for Research on Cancer, Lyon, France
    PLoS ONE 5:e9749. 2010

Collaborators

  • Zdenko Herceg
  • Fabienne Lesueur
  • Alun Thomas
  • Pierre Hainaut
  • Janet Hall
  • Georgia Chenevix-Trench
  • Penelope M Webb
  • Maria Ouzounova
  • Simona Ognjanovic
  • Hector Hernandez-Vargas
  • Sean V Tavtigian
  • Sandrine McKay-Chopin
  • Geoffroy Durand
  • Catherine Voegele
  • Tú Nguyen-Dumont
  • Rosita Accardi
  • Sandra Ortiz-Cuaran
  • Elodie Caboux
  • Sheila C S Lima
  • Suleeporn Sangrajrang
  • Marie Pierre Lambert
  • Nathalie Forey
  • Melissa C Southey
  • Sonia Garritano
  • Birke Bartosch
  • Henri Gruffat
  • Thiravud Khuhaprema
  • Ikbal Fathallah
  • Bakary S Sylla
  • Graham Byrnes
  • Massimo Tommasino
  • Amelie Chabrier
  • Francoise Galateau-Salle
  • Giuseppe Mariggiò
  • Maria Paciencia
  • Evelyne Manet
  • John D Groopman
  • Nivonirina Robinot
  • James McKay
  • David Cox
  • Magdalena B Wozniak
  • Marlin D Friesen
  • Stephanie Villar
  • Chantal Matar
  • Jocelyne Michelon
  • Alain Puisieux
  • Lars P Jordheim
  • Cleber Dario Pinto Kruel
  • Olga Sinilnikova
  • Tatiana Simão
  • Luis Felipe Ribeiro Pinto
  • Géraldine Gouysse
  • Jean Yves Scoazec
  • Anne Hartmann
  • Esther M John
  • Peter J Oefner
  • Deepika de Silva
  • Irene L Andrulis
  • Federica Gemignani
  • Lydie Gioia
  • Graham B Byrnes
  • Mia Hashibe
  • Davit Babikyan
  • Maxime P Vallée
  • Shu Chun Chuang
  • John L Hopper
  • Barbara Herte
  • Sue Healey
  • David C Whiteman
  • Stefano Landi
  • Corinna Feuchtinger

Detail Information

Publications12

  1. pmc MicroRNA miR-30 family regulates non-attachment growth of breast cancer cells
    Maria Ouzounova
    Epigenetics Group, International Agency for Research on Cancer IARC, 150 rue Albert Thomas, Lyon, 69008, France
    BMC Genomics 14:139. 2013
    ..To explore the notion that miRNAs may have a role in sustaining BT-ICs, we performed a comprehensive profiling of miRNA expression in a model of putative BT-ICs enriched by non-attachment growth conditions...
  2. pmc Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study
    Florence Le Calvez-Kelm
    International Agency for Research on Cancer, 150 cours Albert Thomas, Lyon Cedex 08, F 69372, France
    Breast Cancer Res 13:R6. 2011
    ..This absence has been due in part to a lack of validated statistical methods for summarizing risk attributable to large numbers of individually rare missense substitutions...
  3. pmc Detecting differential allelic expression using high-resolution melting curve analysis: application to the breast cancer susceptibility gene CHEK2
    Tú Nguyen-Dumont
    Genetic Cancer Susceptibility Group, IARC, 69372 Lyon, France
    BMC Med Genomics 4:39. 2011
    ..We aimed to assess whether CHEK2 was subject to DAE in lymphoblastoid cell lines (LCLs) from high-risk breast cancer patients for whom no mutation in BRCA1 or BRCA2 had been identified...
  4. pmc Determining the effectiveness of High Resolution Melting analysis for SNP genotyping and mutation scanning at the TP53 locus
    Sonia Garritano
    Department of Biology, Genetics via Derna 1, University of Pisa, Pisa, Italy
    BMC Genet 10:5. 2009
    ..Recently, the use of new fluorescent dyes allowed the high-resolution analysis of DNA melting curves (HRM)...
  5. pmc RAD51 and breast cancer susceptibility: no evidence for rare variant association in the Breast Cancer Family Registry study
    Florence Le Calvez-Kelm
    Genetic Cancer Susceptibility Group, International Agency for Research on Cancer, Lyon, France
    PLoS ONE 7:e52374. 2012
    ..We thus postulated that RAD51 could harbor rare germline mutations that confer increased risk of breast cancer...
  6. ncbi request reprint Methylome analysis reveals Jak-STAT pathway deregulation in putative breast cancer stem cells
    Hector Hernandez-Vargas
    Epigenetics Group, International Agency for Research on Cancer, Lyon, France
    Epigenetics 6:428-39. 2011
    ..In addition, they favor the concept that the expression of cancer stem-like pathways and the establishment and maintenance of defining properties of cancer stem cells are orchestrated by epigenetic mechanisms...
  7. doi request reprint Identification of a DNA methylome signature of esophageal squamous cell carcinoma and potential epigenetic biomarkers
    Sheila C S Lima
    International Agency for Research on Cancer, Lyon, France
    Epigenetics 6:1217-27. 2011
    ..Methylome analysis is shown as a sensitive and powerful tool to identify molecular players in ESCC. These data should prove to be the reference for future studies identifying potential biomarkers and molecular targets in ESCC...
  8. pmc Rare, evolutionarily unlikely missense substitutions in ATM confer increased risk of breast cancer
    Sean V Tavtigian
    International Agency for Research on Cancer, 69372 Lyon, France
    Am J Hum Genet 85:427-46. 2009
    ....
  9. pmc Impact of delay to cryopreservation on RNA integrity and genome-wide expression profiles in resected tumor samples
    Elodie Caboux
    Laboratory Services and Biobank, International Agency for Research on Cancer, Lyon, France
    PLoS ONE 8:e79826. 2013
    ....
  10. pmc Hepatocellular carcinoma displays distinct DNA methylation signatures with potential as clinical predictors
    Hector Hernandez-Vargas
    Epigenetics Group, International Agency for Research on Cancer, Lyon, France
    PLoS ONE 5:e9749. 2010
    ..A better understanding of the global deregulation of methylation states and how they correlate with disease progression will aid in the design of strategies for earlier detection and better therapeutic decisions...
  11. pmc Epstein - Barr virus transforming protein LMP-1 alters B cells gene expression by promoting accumulation of the oncoprotein ΔNp73α
    Rosita Accardi
    International Agency for Research on Cancer, World Health Organization, Lyon, France
    PLoS Pathog 9:e1003186. 2013
    ..Together, these findings reveal a novel EBV mechanism that appears to play an important role in the transformation of primary B cells...
  12. doi request reprint Association between TP53 R249S mutation and polymorphisms in TP53 intron 1 in hepatocellular carcinoma
    Sandra Ortiz-Cuaran
    International Agency for Research on Cancer, Lyon, France
    Genes Chromosomes Cancer 52:912-9. 2013
    ..This domain contains two coding sequences overlapping with TP53 (WRAP53 and Hp53int1) suggesting that sequences in TP53 intron 1 encode transcripts that may modulate R249S mutation rate in HCC...