Research Topics
Genomes and GenesSpecies | Françoise VuillierSummaryAffiliation: Institut Pasteur Country: France Publications
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Detail Information
Publications
Functional monocyte-derived dendritic cells can be generated in chronic lymphocytic leukaemiaF Vuillier
Unité d Immuno Hématologie et d Immunopathologie, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris Cedex 15, France
Br J Haematol 115:831-44. 2001..Overall, these results indicate that it is possible to derive functionally competent DCs from circulating monocytes in CLL patients...
Idiotype-pulsed dendritic cells are able to induce antitumoral cytotoxic CD8 cells in chronic lymphocytic leukaemiaFrançoise Vuillier
Unité d Immuno Hématologie et d Immunopathologie, Institut Pasteur, Paris, France
Br J Haematol 120:243-50. 2003..The failure of cytolytic activity in patients with aggressive disease may be explained by a skewed maturation of memory CD8 cells...
Monocyte-derived dendritic cells in chronic lymphocytic leukemiaFrançoise Vuillier
Unité d Immuno Hématologie et d Immunopathologie, Institut Pasteur, 28 rue du Dr Roux, F 75724 Paris Cedex 15, France
Leuk Lymphoma 44:1267-73. 2003..After summarizing general properties of dendritic cells, this review focus on the approaches exploiting monocyte-derived dendritic cells in CLL, which should help design of novel treatment strategies in this disease...
Lower levels of surface B-cell-receptor expression in chronic lymphocytic leukemia are associated with glycosylation and folding defects of the mu and CD79a chainsFrançoise Vuillier
Unité d Immuno Hématologie et d Immunopathologie, Plate forme de Microscopie Electronique, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris Cedex 15, France
Blood 105:2933-40. 2005..These data show, for the first time, that lower levels of BCR surface expression observed in CLL are accounted for by an impaired glycosylation and folding of the mu and CD79a chains...
Different isoforms of BSAP regulate expression of AID in normal and chronic lymphocytic leukemia B cellsPablo Oppezzo
Unité d Immuno Hématologie et d Immunopathologie, Institut Pasteur, 28 rue Docteur Roux, 75015 Paris, France
Blood 105:2495-503. 2005..Overall, these results suggest that Pax-5/Delta-Ex8 could play an important role in the control of its own transcription and indirectly in AID expression and CSR...
Chronic lymphocytic leukemia B cells expressing AID display dissociation between class switch recombination and somatic hypermutationPablo Oppezzo
Unité d Immuno Hématologie et d Immunopathologie, Institut Pasteur, Paris, France
Blood 101:4029-32. 2003..Our results show a dissociation between SHM and CSR in CLL and suggest that, in this disease, AID would require additional help for carrying out the SHM process...
[Cell therapy by dendritic cells in chronic lymphoid leukemia: state of the art]Françoise Vuillier
Unité d Immuno Hématologie et d Immunopathologie, Institut Pasteur, 28 rue du Dr Roux, 75724 Paris, France
Bull Cancer 90:744-50. 2003..After summarizing general properties of dendritic cells, this review focus on the approaches exploiting monocyte-derived dendritic cells in CLL, which should help design of novel treatment strategies in this disease...
The LPL/ADAM29 expression ratio is a novel prognosis indicator in chronic lymphocytic leukemiaPablo Oppezzo
Unité d Immuno Hématologie et d Immunopathologie, Institut Pasteur, Paris, France
Blood 106:650-7. 2005..Overall, quantification of LPL and ADAM29 gene expression is a strong prognostic indicator in CLL, providing better prognostic assessment than ZAP-70 in advanced stages of the disease...
